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Connection

Francisco Bezanilla to Ion Channel Gating

This is a "connection" page, showing publications Francisco Bezanilla has written about Ion Channel Gating.
Connection Strength

10.079
  1. Tracking the movement of discrete gating charges in a voltage-gated potassium channel. Elife. 2021 11 15; 10.
    View in: PubMed
    Score: 0.674
  2. Metal Bridge in S4 Segment Supports Helix Transition in Shaker Channel. Biophys J. 2020 02 25; 118(4):922-933.
    View in: PubMed
    Score: 0.579
  3. Noncanonical mechanism of voltage sensor coupling to pore revealed by tandem dimers of Shaker. Nat Commun. 2019 08 08; 10(1):3584.
    View in: PubMed
    Score: 0.575
  4. Continuum Gating Current Models Computed with Consistent Interactions. Biophys J. 2019 01 22; 116(2):270-282.
    View in: PubMed
    Score: 0.550
  5. Gating currents. J Gen Physiol. 2018 07 02; 150(7):911-932.
    View in: PubMed
    Score: 0.532
  6. Single-molecule fluorimetry and gating currents inspire an improved optical voltage indicator. Elife. 2015 Nov 24; 4:e10482.
    View in: PubMed
    Score: 0.445
  7. Functional Site-Directed Fluorometry. Adv Exp Med Biol. 2015; 869:55-76.
    View in: PubMed
    Score: 0.418
  8. The gating charge should not be estimated by fitting a two-state model to a Q-V curve. J Gen Physiol. 2013 Dec; 142(6):575-8.
    View in: PubMed
    Score: 0.387
  9. Sensing charges of the Ciona intestinalis voltage-sensing phosphatase. J Gen Physiol. 2013 Nov; 142(5):543-55.
    View in: PubMed
    Score: 0.385
  10. Molecular mechanism for depolarization-induced modulation of Kv channel closure. J Gen Physiol. 2012 Nov; 140(5):481-93.
    View in: PubMed
    Score: 0.359
  11. Control of a final gating charge transition by a hydrophobic residue in the S2 segment of a K+ channel voltage sensor. Proc Natl Acad Sci U S A. 2011 Apr 19; 108(16):6444-9.
    View in: PubMed
    Score: 0.323
  12. Coupling between the voltage-sensing and phosphatase domains of Ci-VSP. J Gen Physiol. 2009 Jul; 134(1):5-14.
    View in: PubMed
    Score: 0.286
  13. A single charged voltage sensor is capable of gating the Shaker K+ channel. J Gen Physiol. 2009 May; 133(5):467-83.
    View in: PubMed
    Score: 0.282
  14. A common pathway for charge transport through voltage-sensing domains. Neuron. 2008 Feb 07; 57(3):345-51.
    View in: PubMed
    Score: 0.259
  15. The origin of subconductance levels in voltage-gated K+ channels. J Gen Physiol. 2005 Aug; 126(2):83-6.
    View in: PubMed
    Score: 0.218
  16. The voltage-sensor structure in a voltage-gated channel. Trends Biochem Sci. 2005 Apr; 30(4):166-8.
    View in: PubMed
    Score: 0.213
  17. Voltage-gated ion channels. IEEE Trans Nanobioscience. 2005 Mar; 4(1):34-48.
    View in: PubMed
    Score: 0.212
  18. Coupling interactions between voltage sensors of the sodium channel as revealed by site-specific measurements. J Gen Physiol. 2004 Mar; 123(3):217-30.
    View in: PubMed
    Score: 0.197
  19. A physical model of potassium channel activation: from energy landscape to gating kinetics. Biophys J. 2003 Jun; 84(6):3703-16.
    View in: PubMed
    Score: 0.187
  20. Tracking voltage-dependent conformational changes in skeletal muscle sodium channel during activation. J Gen Physiol. 2002 Nov; 120(5):629-45.
    View in: PubMed
    Score: 0.180
  21. Voltage sensor movements. J Gen Physiol. 2002 Oct; 120(4):465-73.
    View in: PubMed
    Score: 0.179
  22. Gating current noise produced by Brownian models of a voltage sensor. Biophys J. 2021 09 21; 120(18):3983-4001.
    View in: PubMed
    Score: 0.166
  23. Replacing voltage sensor arginines with citrulline provides mechanistic insight into charge versus shape. J Gen Physiol. 2018 07 02; 150(7):1017-1024.
    View in: PubMed
    Score: 0.133
  24. Nonsensing residues in S3-S4 linker's C terminus affect the voltage sensor set point in K+ channels. J Gen Physiol. 2018 02 05; 150(2):307-321.
    View in: PubMed
    Score: 0.129
  25. LRET Determination of Molecular Distances during pH Gating of the Mammalian Inward Rectifier Kir1.1b. Biophys J. 2018 01 09; 114(1):88-97.
    View in: PubMed
    Score: 0.129
  26. Biophysical Characterization of Genetically Encoded Voltage Sensor ASAP1: Dynamic Range Improvement. Biophys J. 2017 Nov 21; 113(10):2178-2181.
    View in: PubMed
    Score: 0.127
  27. Mechanism of functional interaction between potassium channel Kv1.3 and sodium channel NavBeta1 subunit. Sci Rep. 2017 03 28; 7:45310.
    View in: PubMed
    Score: 0.122
  28. Moving gating charges through the gating pore in a Kv channel voltage sensor. Proc Natl Acad Sci U S A. 2014 May 13; 111(19):E1950-9.
    View in: PubMed
    Score: 0.100
  29. S3-S4 linker length modulates the relaxed state of a voltage-gated potassium channel. Biophys J. 2013 Nov 19; 105(10):2312-22.
    View in: PubMed
    Score: 0.097
  30. Molecular bases for the asynchronous activation of sodium and potassium channels required for nerve impulse generation. Neuron. 2013 Aug 21; 79(4):651-7.
    View in: PubMed
    Score: 0.095
  31. IKs channels open slowly because KCNE1 accessory subunits slow the movement of S4 voltage sensors in KCNQ1 pore-forming subunits. Proc Natl Acad Sci U S A. 2013 Feb 12; 110(7):E559-66.
    View in: PubMed
    Score: 0.092
  32. An emerging consensus on voltage-dependent gating from computational modeling and molecular dynamics simulations. J Gen Physiol. 2012 Dec; 140(6):587-94.
    View in: PubMed
    Score: 0.091
  33. Intermediate state trapping of a voltage sensor. J Gen Physiol. 2012 Dec; 140(6):635-52.
    View in: PubMed
    Score: 0.091
  34. Gating currents from Kv7 channels carrying neuronal hyperexcitability mutations in the voltage-sensing domain. Biophys J. 2012 Mar 21; 102(6):1372-82.
    View in: PubMed
    Score: 0.086
  35. In search of a consensus model of the resting state of a voltage-sensing domain. Neuron. 2011 Dec 08; 72(5):713-20.
    View in: PubMed
    Score: 0.085
  36. Controlling the activity of a phosphatase and tensin homolog (PTEN) by membrane potential. J Biol Chem. 2011 May 20; 286(20):17945-53.
    View in: PubMed
    Score: 0.080
  37. Properties of deactivation gating currents in Shaker channels. Biophys J. 2011 Mar 02; 100(5):L28-30.
    View in: PubMed
    Score: 0.080
  38. The contribution of individual subunits to the coupling of the voltage sensor to pore opening in Shaker K channels: effect of ILT mutations in heterotetramers. J Gen Physiol. 2010 Nov; 136(5):555-68.
    View in: PubMed
    Score: 0.078
  39. Ion channels: from conductance to structure. Neuron. 2008 Nov 06; 60(3):456-68.
    View in: PubMed
    Score: 0.068
  40. S4-based voltage sensors have three major conformations. Proc Natl Acad Sci U S A. 2008 Nov 18; 105(46):17600-7.
    View in: PubMed
    Score: 0.068
  41. How membrane proteins sense voltage. Nat Rev Mol Cell Biol. 2008 Apr; 9(4):323-32.
    View in: PubMed
    Score: 0.065
  42. beta-Scorpion toxin modifies gating transitions in all four voltage sensors of the sodium channel. J Gen Physiol. 2007 Sep; 130(3):257-68.
    View in: PubMed
    Score: 0.063
  43. Detection of the opening of the bundle crossing in KcsA with fluorescence lifetime spectroscopy reveals the existence of two gates for ion conduction. J Gen Physiol. 2006 Nov; 128(5):569-81.
    View in: PubMed
    Score: 0.059
  44. Distance measurements reveal a common topology of prokaryotic voltage-gated ion channels in the lipid bilayer. Proc Natl Acad Sci U S A. 2006 Oct 24; 103(43):15865-70.
    View in: PubMed
    Score: 0.059
  45. Analysis of the optimal channel density of the squid giant axon using a reparameterized Hodgkin-Huxley model. J Neurophysiol. 2006 Aug; 96(2):959; author reply 960.
    View in: PubMed
    Score: 0.058
  46. Optical detection of rate-determining ion-modulated conformational changes of the ether-à-go-go K+ channel voltage sensor. Proc Natl Acad Sci U S A. 2005 Dec 20; 102(51):18718-23.
    View in: PubMed
    Score: 0.056
  47. Small vertical movement of a K+ channel voltage sensor measured with luminescence energy transfer. Nature. 2005 Aug 11; 436(7052):848-51.
    View in: PubMed
    Score: 0.055
  48. Gating charge displacement in voltage-gated ion channels involves limited transmembrane movement. Nature. 2005 Aug 11; 436(7052):852-6.
    View in: PubMed
    Score: 0.055
  49. Gating of the bacterial sodium channel, NaChBac: voltage-dependent charge movement and gating currents. J Gen Physiol. 2004 Oct; 124(4):349-56.
    View in: PubMed
    Score: 0.051
  50. A proton pore in a potassium channel voltage sensor reveals a focused electric field. Nature. 2004 Feb 05; 427(6974):548-53.
    View in: PubMed
    Score: 0.049
  51. Structural biology. Force and voltage sensors in one structure. Science. 2002 Nov 22; 298(5598):1562-3.
    View in: PubMed
    Score: 0.045
  52. Resting state of the human proton channel dimer in a lipid bilayer. Proc Natl Acad Sci U S A. 2015 Nov 03; 112(44):E5926-35.
    View in: PubMed
    Score: 0.028
  53. Domain IV voltage-sensor movement is both sufficient and rate limiting for fast inactivation in sodium channels. J Gen Physiol. 2013 Aug; 142(2):101-12.
    View in: PubMed
    Score: 0.024
  54. Alpha-scorpion toxin impairs a conformational change that leads to fast inactivation of muscle sodium channels. J Gen Physiol. 2008 Aug; 132(2):251-63.
    View in: PubMed
    Score: 0.017
  55. Movement of 'gating charge' is coupled to ligand binding in a G-protein-coupled receptor. Nature. 2006 Nov 02; 444(7115):106-9.
    View in: PubMed
    Score: 0.015
  56. Silicon chip-based patch-clamp electrodes integrated with PDMS microfluidics. Biosens Bioelectron. 2004 Oct 15; 20(3):509-17.
    View in: PubMed
    Score: 0.013
  57. A fluorophore attached to nicotinic acetylcholine receptor beta M2 detects productive binding of agonist to the alpha delta site. Proc Natl Acad Sci U S A. 2004 Jul 06; 101(27):10195-200.
    View in: PubMed
    Score: 0.013
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.