Francisco Bezanilla to Ion Channel Gating
This is a "connection" page, showing publications Francisco Bezanilla has written about Ion Channel Gating.
Connection Strength
12.175
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Evolution of our understanding of the sodium channel fast inactivation: From Hodgkin and Huxley to the structural era. J Gen Physiol. 2026 Jul 06; 158(4).
Score: 0.790
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Quantifying activation delay and the Cole-More shift via current derivatives. Biophys J. 2026 02 03; 125(3):688-696.
Score: 0.767
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Molecular basis of sodium channel inactivation. Nat Commun. 2025 Nov 26; 16(1):10565.
Score: 0.766
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A sodium channel mutant removes fast inactivation with the inactivation particle bound. J Gen Physiol. 2025 01 06; 157(1).
Score: 0.715
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Tracking the movement of discrete gating charges in a voltage-gated potassium channel. Elife. 2021 11 15; 10.
Score: 0.579
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Metal Bridge in S4 Segment Supports Helix Transition in Shaker Channel. Biophys J. 2020 02 25; 118(4):922-933.
Score: 0.497
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Noncanonical mechanism of voltage sensor coupling to pore revealed by tandem dimers of Shaker. Nat Commun. 2019 08 08; 10(1):3584.
Score: 0.495
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Continuum Gating Current Models Computed with Consistent Interactions. Biophys J. 2019 01 22; 116(2):270-282.
Score: 0.473
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Gating currents. J Gen Physiol. 2018 07 02; 150(7):911-932.
Score: 0.458
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Single-molecule fluorimetry and gating currents inspire an improved optical voltage indicator. Elife. 2015 Nov 24; 4:e10482.
Score: 0.383
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Functional Site-Directed Fluorometry. Adv Exp Med Biol. 2015; 869:55-76.
Score: 0.360
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The gating charge should not be estimated by fitting a two-state model to a Q-V curve. J Gen Physiol. 2013 Dec; 142(6):575-8.
Score: 0.332
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Sensing charges of the Ciona intestinalis voltage-sensing phosphatase. J Gen Physiol. 2013 Nov; 142(5):543-55.
Score: 0.331
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Molecular mechanism for depolarization-induced modulation of Kv channel closure. J Gen Physiol. 2012 Nov; 140(5):481-93.
Score: 0.309
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Control of a final gating charge transition by a hydrophobic residue in the S2 segment of a K+ channel voltage sensor. Proc Natl Acad Sci U S A. 2011 Apr 19; 108(16):6444-9.
Score: 0.277
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Coupling between the voltage-sensing and phosphatase domains of Ci-VSP. J Gen Physiol. 2009 Jul; 134(1):5-14.
Score: 0.246
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A single charged voltage sensor is capable of gating the Shaker K+ channel. J Gen Physiol. 2009 May; 133(5):467-83.
Score: 0.243
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A common pathway for charge transport through voltage-sensing domains. Neuron. 2008 Feb 07; 57(3):345-51.
Score: 0.223
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Closed state structure of the pore revealed by uncoupled Shaker K+ channel. Nat Commun. 2025 Nov 19; 16(1):10180.
Score: 0.191
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The origin of subconductance levels in voltage-gated K+ channels. J Gen Physiol. 2005 Aug; 126(2):83-6.
Score: 0.187
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Energy landscape of a Kv channel revealed by temperature steps while perturbing its electromechanical coupling. Nat Commun. 2025 Apr 09; 16(1):3379.
Score: 0.183
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The voltage-sensor structure in a voltage-gated channel. Trends Biochem Sci. 2005 Apr; 30(4):166-8.
Score: 0.183
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Voltage-gated ion channels. IEEE Trans Nanobioscience. 2005 Mar; 4(1):34-48.
Score: 0.182
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Coupling interactions between voltage sensors of the sodium channel as revealed by site-specific measurements. J Gen Physiol. 2004 Mar; 123(3):217-30.
Score: 0.170
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A physical model of potassium channel activation: from energy landscape to gating kinetics. Biophys J. 2003 Jun; 84(6):3703-16.
Score: 0.161
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Tracking voltage-dependent conformational changes in skeletal muscle sodium channel during activation. J Gen Physiol. 2002 Nov; 120(5):629-45.
Score: 0.155
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Voltage sensor movements. J Gen Physiol. 2002 Oct; 120(4):465-73.
Score: 0.154
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Gating current noise produced by Brownian models of a voltage sensor. Biophys J. 2021 09 21; 120(18):3983-4001.
Score: 0.142
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Replacing voltage sensor arginines with citrulline provides mechanistic insight into charge versus shape. J Gen Physiol. 2018 07 02; 150(7):1017-1024.
Score: 0.114
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Nonsensing residues in S3-S4 linker's C terminus affect the voltage sensor set point in K+ channels. J Gen Physiol. 2018 02 05; 150(2):307-321.
Score: 0.111
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LRET Determination of Molecular Distances during pH Gating of the Mammalian Inward Rectifier Kir1.1b. Biophys J. 2018 01 09; 114(1):88-97.
Score: 0.111
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Biophysical Characterization of Genetically Encoded Voltage Sensor ASAP1: Dynamic Range Improvement. Biophys J. 2017 Nov 21; 113(10):2178-2181.
Score: 0.110
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Mechanism of functional interaction between potassium channel Kv1.3 and sodium channel NavBeta1 subunit. Sci Rep. 2017 03 28; 7:45310.
Score: 0.105
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Moving gating charges through the gating pore in a Kv channel voltage sensor. Proc Natl Acad Sci U S A. 2014 May 13; 111(19):E1950-9.
Score: 0.086
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S3-S4 linker length modulates the relaxed state of a voltage-gated potassium channel. Biophys J. 2013 Nov 19; 105(10):2312-22.
Score: 0.083
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Molecular bases for the asynchronous activation of sodium and potassium channels required for nerve impulse generation. Neuron. 2013 Aug 21; 79(4):651-7.
Score: 0.082
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IKs channels open slowly because KCNE1 accessory subunits slow the movement of S4 voltage sensors in KCNQ1 pore-forming subunits. Proc Natl Acad Sci U S A. 2013 Feb 12; 110(7):E559-66.
Score: 0.079
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An emerging consensus on voltage-dependent gating from computational modeling and molecular dynamics simulations. J Gen Physiol. 2012 Dec; 140(6):587-94.
Score: 0.078
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Intermediate state trapping of a voltage sensor. J Gen Physiol. 2012 Dec; 140(6):635-52.
Score: 0.078
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Gating currents from Kv7 channels carrying neuronal hyperexcitability mutations in the voltage-sensing domain. Biophys J. 2012 Mar 21; 102(6):1372-82.
Score: 0.074
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In search of a consensus model of the resting state of a voltage-sensing domain. Neuron. 2011 Dec 08; 72(5):713-20.
Score: 0.073
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Controlling the activity of a phosphatase and tensin homolog (PTEN) by membrane potential. J Biol Chem. 2011 May 20; 286(20):17945-53.
Score: 0.069
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Properties of deactivation gating currents in Shaker channels. Biophys J. 2011 Mar 02; 100(5):L28-30.
Score: 0.069
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The contribution of individual subunits to the coupling of the voltage sensor to pore opening in Shaker K channels: effect of ILT mutations in heterotetramers. J Gen Physiol. 2010 Nov; 136(5):555-68.
Score: 0.067
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Ion channels: from conductance to structure. Neuron. 2008 Nov 06; 60(3):456-68.
Score: 0.059
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S4-based voltage sensors have three major conformations. Proc Natl Acad Sci U S A. 2008 Nov 18; 105(46):17600-7.
Score: 0.058
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How membrane proteins sense voltage. Nat Rev Mol Cell Biol. 2008 Apr; 9(4):323-32.
Score: 0.056
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beta-Scorpion toxin modifies gating transitions in all four voltage sensors of the sodium channel. J Gen Physiol. 2007 Sep; 130(3):257-68.
Score: 0.054
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Detection of the opening of the bundle crossing in KcsA with fluorescence lifetime spectroscopy reveals the existence of two gates for ion conduction. J Gen Physiol. 2006 Nov; 128(5):569-81.
Score: 0.051
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Distance measurements reveal a common topology of prokaryotic voltage-gated ion channels in the lipid bilayer. Proc Natl Acad Sci U S A. 2006 Oct 24; 103(43):15865-70.
Score: 0.051
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Dynamical Nonequilibrium Molecular Dynamics Simulations Reveal Atomistic Steps of C-Type Inactivation in Cardiac hERG Channels. J Am Chem Soc. 2026 09 09; 148(35):37738-37750.
Score: 0.051
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Analysis of the optimal channel density of the squid giant axon using a reparameterized Hodgkin-Huxley model. J Neurophysiol. 2006 Aug; 96(2):959; author reply 960.
Score: 0.050
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Optical detection of rate-determining ion-modulated conformational changes of the ether-à-go-go K+ channel voltage sensor. Proc Natl Acad Sci U S A. 2005 Dec 20; 102(51):18718-23.
Score: 0.048
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Small vertical movement of a K+ channel voltage sensor measured with luminescence energy transfer. Nature. 2005 Aug 11; 436(7052):848-51.
Score: 0.047
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Gating charge displacement in voltage-gated ion channels involves limited transmembrane movement. Nature. 2005 Aug 11; 436(7052):852-6.
Score: 0.047
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Isoleucine gate blocks K+ conduction in C-type inactivation. Elife. 2024 Nov 12; 13.
Score: 0.045
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Gating of the bacterial sodium channel, NaChBac: voltage-dependent charge movement and gating currents. J Gen Physiol. 2004 Oct; 124(4):349-56.
Score: 0.044
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A proton pore in a potassium channel voltage sensor reveals a focused electric field. Nature. 2004 Feb 05; 427(6974):548-53.
Score: 0.042
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Structural biology. Force and voltage sensors in one structure. Science. 2002 Nov 22; 298(5598):1562-3.
Score: 0.039
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Resting state of the human proton channel dimer in a lipid bilayer. Proc Natl Acad Sci U S A. 2015 Nov 03; 112(44):E5926-35.
Score: 0.024
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Domain IV voltage-sensor movement is both sufficient and rate limiting for fast inactivation in sodium channels. J Gen Physiol. 2013 Aug; 142(2):101-12.
Score: 0.020
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Alpha-scorpion toxin impairs a conformational change that leads to fast inactivation of muscle sodium channels. J Gen Physiol. 2008 Aug; 132(2):251-63.
Score: 0.014
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Movement of 'gating charge' is coupled to ligand binding in a G-protein-coupled receptor. Nature. 2006 Nov 02; 444(7115):106-9.
Score: 0.013
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Silicon chip-based patch-clamp electrodes integrated with PDMS microfluidics. Biosens Bioelectron. 2004 Oct 15; 20(3):509-17.
Score: 0.011
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A fluorophore attached to nicotinic acetylcholine receptor beta M2 detects productive binding of agonist to the alpha delta site. Proc Natl Acad Sci U S A. 2004 Jul 06; 101(27):10195-200.
Score: 0.011