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Connection

Hening Lin to Structure-Activity Relationship

This is a "connection" page, showing publications Hening Lin has written about Structure-Activity Relationship.
Connection Strength

0.771
  1. A Mitochondria-Targeting SIRT3 Inhibitor with Activity against Diffuse Large B Cell Lymphoma. J Med Chem. 2024 09 12; 67(17):15428-15437.
    View in: PubMed
    Score: 0.200
  2. Novel Lysine-Based Thioureas as Mechanism-Based Inhibitors of Sirtuin 2 (SIRT2) with Anticancer Activity in a Colorectal Cancer Murine Model. J Med Chem. 2019 04 25; 62(8):4131-4141.
    View in: PubMed
    Score: 0.138
  3. Direct Comparison of SIRT2 Inhibitors: Potency, Specificity, Activity-Dependent Inhibition, and On-Target Anticancer Activities. ChemMedChem. 2018 09 19; 13(18):1890-1894.
    View in: PubMed
    Score: 0.132
  4. Thiosuccinyl peptides as Sirt5-specific inhibitors. J Am Chem Soc. 2012 Feb 01; 134(4):1922-5.
    View in: PubMed
    Score: 0.084
  5. Attenuation of NLRP3 Inflammasome Activation by Indirubin-Derived PROTAC Targeting HDAC6. ACS Chem Biol. 2021 12 17; 16(12):2746-2751.
    View in: PubMed
    Score: 0.041
  6. Indirubin Derivatives as Dual Inhibitors Targeting Cyclin-Dependent Kinase and Histone Deacetylase for Treating Cancer. J Med Chem. 2021 10 28; 64(20):15280-15296.
    View in: PubMed
    Score: 0.041
  7. High-Throughput Screening Identifies Ascorbyl Palmitate as a SIRT2 Deacetylase and Defatty-Acylase Inhibitor. ChemMedChem. 2021 11 19; 16(22):3484-3494.
    View in: PubMed
    Score: 0.041
  8. Cysteine derivatives as acetyl lysine mimics to inhibit zinc-dependent histone deacetylases for treating cancer. Eur J Med Chem. 2021 Dec 05; 225:113799.
    View in: PubMed
    Score: 0.041
  9. HDAC1 Governs Iron Homeostasis Independent of Histone Deacetylation in Iron-Overload Murine Models. Antioxid Redox Signal. 2018 05 01; 28(13):1224-1237.
    View in: PubMed
    Score: 0.031
  10. The bicyclic intermediate structure provides insights into the desuccinylation mechanism of human sirtuin 5 (SIRT5). J Biol Chem. 2012 Aug 17; 287(34):28307-14.
    View in: PubMed
    Score: 0.022
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.