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Noura Choudhury

TitleAssistant Professor
InstitutionUniversity of Chicago
DepartmentMedicine-Hematology and Oncology
AddressChicago IL 60637
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    Dr. Noura Choudhury is a highly skilled and compassionate medical oncologist dedicated to providing exceptional care to patients with thoracic and head and neck malignancies. Dr. Choudhury is also a clinical and translational investigator, with a particular focus in small cell lung cancer. Her expertise is grounded in years of dedicated experience, which allows her to provide personalized care that addresses each patient’s unique needs.

    Using a patient-centered approach to care, Dr. Choudhury ensures that each treatment plan is tailored to her patients’ specific condition, symptoms, lifestyle and healthcare goals. By integrating the latest advancements in cancer care, she strives to enhance the overall well-being of her patients. She has expertise in standard of care treatments such as chemotherapy, immunotherapy and targeted therapies, as well as novel therapeutics such as bispecific T cell engagers, antibody drug conjugates and bispecific antibodies.

    In additional to her clinical work, Dr. Choudhury actively develops clinical trials, contributing to the advancement of cancer treatment. She is national Principal Investigator of an investigator-initiated National Cancer Institute (NCI) phase I/II study in small cell lung cancer, as well as the principal investigator of multiple phase I clinical trials, including first-in-human studies of novel therapeutics. She is a translational physician scientist who strives to bring discoveries in the laboratory to patients in the clinic. Her involvement in leading-edge research allows her to offer her patients access to new therapies and innovative treatments, improving their outcomes and quality of life. Her work also focuses on identifying mechanisms of response and resistance to novel treatment strategies. She is an author on numerous publications, with her work has been published in The Lancet, Clinical Cancer Research, Journal of Thoracic Oncology, Journal of Clinical Oncology, Annals of Oncology, among others.

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Rosenberg AJ, Izumchenko E, Juloori A, Katipally R, Cursio J, Choudhury N, Gooi Z, Blair E, Chin J, Hasina R, Vannier A, Starus A, Jones FS, Gramiccioni EL, Miao Y, Haraf DJ, Vokes EE, Pearson AT, Agrawal N. Early dynamics of circulating tumor HPV-DNA with neoadjuvant chemotherapy and response-adapted de-escalation in human papillomavirus-associated oropharyngeal cancer. Clin Cancer Res. 2025 May 27. PMID: 40423530.
      Citations:    Fields:    Translation:HumansCells
    2. Morgensztern D, Ready N, Johnson ML, Dowlati A, Choudhury N, Carbone DP, Schaefer E, Arnold SM, Puri S, Piotrowska Z, Hegde A, Chiang AC, Iams W, Tolcher A, Nosaki K, Kozuki T, Li T, Santana-Davila R, Akamatsu H, Murakami H, Yokouchi H, Wang S, Zha J, Li R, Robinson RR, Hingorani P, Jeng EE, Furqan M. A Phase I First-in-Human Study of ABBV-011, a Seizure-Related Homolog Protein 6-Targeting Antibody-Drug Conjugate, in Patients with Small Cell Lung Cancer. Clin Cancer Res. 2024 Nov 15; 30(22):5042-5052. PMID: 39287821; PMCID: PMC11565168.
      Citations: 15     Fields:    Translation:HumansCTClinical Trials
    3. Choudhury NJ, Lai WV, Makhnin A, Heller G, Eng J, Li B, Preeshagul I, Santini FC, Offin M, Ng K, Paik P, Larsen C, Ginsberg MS, Lau Y, Zhang X, Baine MK, Rekhtman N, Rudin CM. A Phase I/II Study of Valemetostat (DS-3201b), an EZH1/2 Inhibitor, in Combination with Irinotecan in Patients with Recurrent Small-Cell Lung Cancer. Clin Cancer Res. 2024 Sep 03; 30(17):3697-3703. PMID: 38940666; PMCID: PMC11371507.
      Citations: 11     Fields:    Translation:HumansCTClinical Trials
    4. Choudhury NJ, Lavery JA, Brown S, de Bruijn I, Jee J, Tran TN, Rizvi H, Arbour KC, Whiting K, Shen R, Hellmann M, Bedard PL, Yu C, Leighl N, LeNoue-Newton M, Micheel C, Warner JL, Ginsberg MS, Plodkowski A, Girshman J, Sawan P, Pillai S, Sweeney SM, Kehl KL, Panageas KS, Schultz N, Schrag D, Riely GJ, AACR GENIE BPC Core Team. The GENIE BPC NSCLC Cohort: A Real-World Repository Integrating Standardized Clinical and Genomic Data for 1,846 Patients with Non-Small Cell Lung Cancer. Clin Cancer Res. 2023 09 01; 29(17):3418-3428. PMID: 37223888; PMCID: PMC10472103.
      Citations: 13     Fields:    Translation:Humans
    5. Rudin CM, Balli D, Lai WV, Richards AL, Nguyen E, Egger JV, Choudhury NJ, Sen T, Chow A, Poirier JT, Geese WJ, Hellmann MD, Forslund A. Clinical Benefit From Immunotherapy in Patients With SCLC Is Associated With Tumor Capacity for Antigen Presentation. J Thorac Oncol. 2023 09; 18(9):1222-1232. PMID: 37210008; PMCID: PMC10524620.
      Citations: 42     Fields:    Translation:HumansCTClinical Trials
    6. Solomon JP, Yang SR, Choudhury NJ, Ptashkin RN, Eslamdoost N, Falcon CJ, Martin A, Plodkowski A, Wilhelm C, Shen R, Ladanyi M, Berger M, Zhang Y, Drilon A, Arcila ME. Bioinformatically Expanded Next-Generation Sequencing Analysis Optimizes Identification of Therapeutically Relevant MET Copy Number Alterations in >50,000 Tumors. Clin Cancer Res. 2022 11 01; 28(21):4649-4659. PMID: 36044468; PMCID: PMC9633455.
      Citations: 7     Fields:    Translation:Humans
    7. Choudhury NJ, Makhnin A, Tobi YY, Daly RM, Preeshagul IR, Iqbal AN, Ahn LS, Hayes SA, Heller G, Kris MG, Riely GJ, Yu HA. Pilot Study of Dacomitinib for Patients With Metastatic EGFR-Mutant Lung Cancers With Disease Progression After Initial Treatment With Osimertinib. JCO Precis Oncol. 2021; 5. PMID: 34250398; PMCID: PMC8232442.
      Citations: 10     Fields:    Translation:HumansCTClinical Trials
    8. Lin JJ, Choudhury NJ, Yoda S, Zhu VW, Johnson TW, Sakhtemani R, Dagogo-Jack I, Digumarthy SR, Lee C, Do A, Peterson J, Prutisto-Chang K, Malik W, Hubbeling HG, Langenbucher A, Schoenfeld AJ, Falcon CJ, Temel JS, Sequist LV, Yeap BY, Lennerz JK, Shaw AT, Lawrence MS, Ou SI, Hata AN, Drilon A, Gainor JF. Spectrum of Mechanisms of Resistance to Crizotinib and Lorlatinib in ROS1 Fusion-Positive Lung Cancer. Clin Cancer Res. 2021 05 15; 27(10):2899-2909. PMID: 33685866; PMCID: PMC8127383.
      Citations: 74     Fields:    Translation:HumansCells
    9. Choudhury NJ, Schoenfeld AJ, Flynn J, Falcon CJ, Rizvi H, Rudin CM, Kris MG, Arcila ME, Heller G, Yu HA, Ladanyi M, Riely GJ. Response to Standard Therapies and Comprehensive Genomic Analysis for Patients with Lung Adenocarcinoma with EGFR Exon 20 Insertions. Clin Cancer Res. 2021 05 15; 27(10):2920-2927. PMID: 33685865; PMCID: PMC8127357.
      Citations: 31     Fields:    Translation:Humans
    10. Choudhury NJ, Eghtesad M, Kadri S, Cursio J, Ritterhouse L, Segal J, Husain A, Patel JD. Fewer actionable mutations but higher tumor mutational burden characterizes NSCLC in black patients at an urban academic medical center. Oncotarget. 2019 Oct 08; 10(56):5817-5823. PMID: 31645901; PMCID: PMC6791384.
      Citations: 12     Fields:    
    11. Liu H, Zha Y, Choudhury N, Malnassy G, Fulton N, Green M, Park JH, Nakamura Y, Larson RA, Salazar AM, Odenike O, Gajewski TF, Stock W. WT1 peptide vaccine in Montanide in contrast to poly ICLC, is able to induce WT1-specific immune response with TCR clonal enrichment in myeloid leukemia. Exp Hematol Oncol. 2018; 7:1. PMID: 29344432; PMCID: PMC5765712.
      Citations: 12     
    12. Choudhury NJ, Campanile A, Antic T, Yap KL, Fitzpatrick CA, Wade JL, Karrison T, Stadler WM, Nakamura Y, O'Donnell PH. Afatinib Activity in Platinum-Refractory Metastatic Urothelial Carcinoma in Patients With ERBB Alterations. J Clin Oncol. 2016 06 20; 34(18):2165-71. PMID: 27044931; PMCID: PMC5569685.
      Citations: 95     Fields:    Translation:HumansCTClinical Trials
    13. Choudhury N, Nakamura Y. Importance of immunopharmacogenomics in cancer treatment: Patient selection and monitoring for immune checkpoint antibodies. Cancer Sci. 2016 Feb; 107(2):107-15. PMID: 26678880; PMCID: PMC4768396.
      Citations: 16     Fields:    Translation:Humans
    14. Choudhury NJ, Kiyotani K, Yap KL, Campanile A, Antic T, Yew PY, Steinberg G, Park JH, Nakamura Y, O'Donnell PH. Low T-cell Receptor Diversity, High Somatic Mutation Burden, and High Neoantigen Load as Predictors of Clinical Outcome in Muscle-invasive Bladder Cancer. Eur Urol Focus. 2016 Oct; 2(4):445-452. PMID: 28723478.
      Citations: 51     Fields:    
    15. Xu J, Prosperi JR, Choudhury N, Olopade OI, Goss KH. ß-Catenin is required for the tumorigenic behavior of triple-negative breast cancer cells. PLoS One. 2015; 10(2):e0117097. PMID: 25658419; PMCID: PMC4319896.
      Citations: 109     Fields:    Translation:HumansAnimalsCells
    16. Choudhury N, Khanwalkar A, Kraninger J, Vohra A, Jones K, Reddy S. Peer mentorship in student-run free clinics: the impact on preclinical education. Fam Med. 2014 Mar; 46(3):204-8. PMID: 24652639.
      Citations: 7     Fields:    Translation:Humans
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