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Connection

Jeffrey Rathmell to Glucose

This is a "connection" page, showing publications Jeffrey Rathmell has written about Glucose.
Connection Strength

5.960
  1. Suppression of Glut1 and Glucose Metabolism by Decreased Akt/mTORC1 Signaling Drives T Cell Impairment in B Cell Leukemia. J Immunol. 2016 09 15; 197(6):2532-40.
    View in: PubMed
    Score: 0.417
  2. Akt-dependent glucose metabolism promotes Mcl-1 synthesis to maintain cell survival and resistance to Bcl-2 inhibition. Cancer Res. 2011 Aug 01; 71(15):5204-13.
    View in: PubMed
    Score: 0.292
  3. Akt requires glucose metabolism to suppress puma expression and prevent apoptosis of leukemic T cells. J Biol Chem. 2011 Feb 18; 286(7):5921-33.
    View in: PubMed
    Score: 0.282
  4. Biochemistry. A glucose-to-gene link. Science. 2009 May 22; 324(5930):1021-2.
    View in: PubMed
    Score: 0.253
  5. Glucose metabolism attenuates p53 and Puma-dependent cell death upon growth factor deprivation. J Biol Chem. 2008 Dec 26; 283(52):36344-53.
    View in: PubMed
    Score: 0.244
  6. Glucose metabolism in lymphocytes is a regulated process with significant effects on immune cell function and survival. J Leukoc Biol. 2008 Oct; 84(4):949-57.
    View in: PubMed
    Score: 0.237
  7. Glucose uptake is limiting in T cell activation and requires CD28-mediated Akt-dependent and independent pathways. J Immunol. 2008 Apr 01; 180(7):4476-86.
    View in: PubMed
    Score: 0.234
  8. Mechanisms and methods in glucose metabolism and cell death. Methods Enzymol. 2008; 442:439-57.
    View in: PubMed
    Score: 0.230
  9. IL-7 promotes Glut1 trafficking and glucose uptake via STAT5-mediated activation of Akt to support T-cell survival. Blood. 2008 Feb 15; 111(4):2101-11.
    View in: PubMed
    Score: 0.228
  10. Glycogen synthase kinase 3alpha and 3beta mediate a glucose-sensitive antiapoptotic signaling pathway to stabilize Mcl-1. Mol Cell Biol. 2007 Jun; 27(12):4328-39.
    View in: PubMed
    Score: 0.217
  11. Cytokine stimulation promotes glucose uptake via phosphatidylinositol-3 kinase/Akt regulation of Glut1 activity and trafficking. Mol Biol Cell. 2007 Apr; 18(4):1437-46.
    View in: PubMed
    Score: 0.216
  12. Lymphocyte selection by starvation: glucose metabolism and cell death. Trends Immunol. 2006 Jan; 27(1):4-7.
    View in: PubMed
    Score: 0.198
  13. Plasma Cell Differentiation, Antibody Quality, and Initial Germinal Center B Cell Population Depend on Glucose Influx Rate. J Immunol. 2024 01 01; 212(1):43-56.
    View in: PubMed
    Score: 0.174
  14. The glucose transporter 2 regulates CD8+ T cell function via environment sensing. Nat Metab. 2023 Nov; 5(11):1969-1985.
    View in: PubMed
    Score: 0.172
  15. Akt-directed glucose metabolism can prevent Bax conformation change and promote growth factor-independent survival. Mol Cell Biol. 2003 Oct; 23(20):7315-28.
    View in: PubMed
    Score: 0.171
  16. CD28 costimulation drives tumor-infiltrating T cell glycolysis to promote inflammation. JCI Insight. 2020 08 20; 5(16).
    View in: PubMed
    Score: 0.138
  17. Combined deletion of Glut1 and Glut3 impairs lung adenocarcinoma growth. Elife. 2020 06 23; 9.
    View in: PubMed
    Score: 0.136
  18. Impaired enolase 1 glycolytic activity restrains effector functions of tumor-infiltrating CD8+ T cells. Sci Immunol. 2019 01 25; 4(31).
    View in: PubMed
    Score: 0.124
  19. Efferocytosis induces a novel SLC program to promote glucose uptake and lactate release. Nature. 2018 11; 563(7733):714-718.
    View in: PubMed
    Score: 0.122
  20. Differential glucose requirement in skin homeostasis and injury identifies a therapeutic target for psoriasis. Nat Med. 2018 05; 24(5):617-627.
    View in: PubMed
    Score: 0.117
  21. A Predictive Model for Selective Targeting of the Warburg Effect through GAPDH Inhibition with a Natural Product. Cell Metab. 2017 Oct 03; 26(4):648-659.e8.
    View in: PubMed
    Score: 0.113
  22. Nutrients and the microenvironment to feed a T cell army. Semin Immunol. 2016 10; 28(5):505-513.
    View in: PubMed
    Score: 0.105
  23. mTORC1 and mTORC2 Kinase Signaling and Glucose Metabolism Drive Follicular Helper T Cell Differentiation. Immunity. 2016 09 20; 45(3):540-554.
    View in: PubMed
    Score: 0.105
  24. Amino Acids Rather than Glucose Account for the Majority of Cell Mass in Proliferating Mammalian Cells. Dev Cell. 2016 Mar 07; 36(5):540-9.
    View in: PubMed
    Score: 0.101
  25. Novel therapeutic targets of tumor metabolism. Cancer J. 2015 Mar-Apr; 21(2):62-9.
    View in: PubMed
    Score: 0.094
  26. Glucose availability and glycolytic metabolism dictate glycosphingolipid levels. J Cell Biochem. 2015 Jan; 116(1):67-80.
    View in: PubMed
    Score: 0.093
  27. Metabolic reprogramming towards aerobic glycolysis correlates with greater proliferative ability and resistance to metabolic inhibition in CD8 versus CD4 T cells. PLoS One. 2014; 9(8):e104104.
    View in: PubMed
    Score: 0.091
  28. The glucose transporter Glut1 is selectively essential for CD4 T cell activation and effector function. Cell Metab. 2014 Jul 01; 20(1):61-72.
    View in: PubMed
    Score: 0.090
  29. Metabolic reprogramming is required for antibody production that is suppressed in anergic but exaggerated in chronically BAFF-exposed B cells. J Immunol. 2014 Apr 15; 192(8):3626-36.
    View in: PubMed
    Score: 0.088
  30. Matched and mismatched metabolic fuels in lymphocyte function. Semin Immunol. 2012 Dec; 24(6):405-13.
    View in: PubMed
    Score: 0.081
  31. Metabolic pathways in T cell fate and function. Trends Immunol. 2012 Apr; 33(4):168-73.
    View in: PubMed
    Score: 0.076
  32. Estrogen-related receptor-a is a metabolic regulator of effector T-cell activation and differentiation. Proc Natl Acad Sci U S A. 2011 Nov 08; 108(45):18348-53.
    View in: PubMed
    Score: 0.075
  33. TGF-beta: a new role for an old AktTOR. Dev Cell. 2009 Jul; 17(1):6-8.
    View in: PubMed
    Score: 0.064
  34. An essential role for the Glut1 PDZ-binding motif in growth factor regulation of Glut1 degradation and trafficking. Biochem J. 2009 Mar 01; 418(2):345-67.
    View in: PubMed
    Score: 0.062
  35. Autophagy provides nutrients but can lead to Chop-dependent induction of Bim to sensitize growth factor-deprived cells to apoptosis. Mol Biol Cell. 2009 Feb; 20(4):1180-91.
    View in: PubMed
    Score: 0.061
  36. Glucose metabolism as a target of histone deacetylase inhibitors. Mol Endocrinol. 2009 Mar; 23(3):388-401.
    View in: PubMed
    Score: 0.061
  37. Isoform-specific requirement for Akt1 in the developmental regulation of cellular metabolism during lactation. Cell Metab. 2006 Dec; 4(6):475-90.
    View in: PubMed
    Score: 0.053
  38. Metabolite profiling of human renal cell carcinoma reveals tissue-origin dominance in nutrient availability. Elife. 2024 May 24; 13.
    View in: PubMed
    Score: 0.045
  39. Neurons require glucose uptake and glycolysis in vivo. Cell Rep. 2023 04 25; 42(4):112335.
    View in: PubMed
    Score: 0.041
  40. Characterization of metabolic alterations of chronic lymphocytic leukemia in the lymph node microenvironment. Blood. 2022 08 11; 140(6):630-643.
    View in: PubMed
    Score: 0.040
  41. The CD28 signaling pathway regulates glucose metabolism. Immunity. 2002 Jun; 16(6):769-77.
    View in: PubMed
    Score: 0.039
  42. Cell-programmed nutrient partitioning in the tumour microenvironment. Nature. 2021 05; 593(7858):282-288.
    View in: PubMed
    Score: 0.036
  43. ERRa-Regulated Lactate Metabolism Contributes to Resistance to Targeted Therapies in Breast Cancer. Cell Rep. 2016 Apr 12; 15(2):323-35.
    View in: PubMed
    Score: 0.025
  44. MYC Disrupts the Circadian Clock and Metabolism in Cancer Cells. Cell Metab. 2015 Dec 01; 22(6):1009-19.
    View in: PubMed
    Score: 0.024
  45. HIF1a and HIF2a exert distinct nutrient preferences in renal cells. PLoS One. 2014; 9(5):e98705.
    View in: PubMed
    Score: 0.022
  46. Leptin metabolically licenses T cells for activation to link nutrition and immunity. J Immunol. 2014 Jan 01; 192(1):136-44.
    View in: PubMed
    Score: 0.022
  47. Akt1 and Akt2 are required for alphabeta thymocyte survival and differentiation. Proc Natl Acad Sci U S A. 2007 Jul 17; 104(29):12105-10.
    View in: PubMed
    Score: 0.014
  48. Metabolic regulation of oocyte cell death through the CaMKII-mediated phosphorylation of caspase-2. Cell. 2005 Oct 07; 123(1):89-103.
    View in: PubMed
    Score: 0.012
  49. Cytokine stimulation of aerobic glycolysis in hematopoietic cells exceeds proliferative demand. FASEB J. 2004 Aug; 18(11):1303-5.
    View in: PubMed
    Score: 0.011
  50. Homeostatic control of lymphocyte survival: potential origins and implications. Nat Immunol. 2002 Jun; 3(6):515-21.
    View in: PubMed
    Score: 0.010
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.