| Item Type | Name |
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Concept
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Epidemiologic Methods
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Concept
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Models, Molecular
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Concept
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Models, Cardiovascular
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Concept
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Models, Genetic
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Concept
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Models, Theoretical
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Concept
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Linear Models
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Concept
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Proportional Hazards Models
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Concept
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Models, Animal
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Concept
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Models, Statistical
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Concept
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Logistic Models
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Concept
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Disease Models, Animal
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Concept
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Models, Biological
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Academic Article
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Accurate inference of relationships in sib-pair linkage studies.
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Academic Article
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Allele-sharing models: LOD scores and accurate linkage tests.
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Academic Article
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Genetic inheritance of body mass index in African-American and African families.
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Academic Article
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Genome-wide linkage analyses of total serum IgE using variance components analysis in asthmatic families.
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Academic Article
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Challenges in identifying genetic variation affecting susceptibility to type 2 diabetes: examples from studies of the calpain-10 gene.
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Academic Article
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A statistical method for identification of polymorphisms that explain a linkage result.
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Academic Article
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Genetic Analysis Workshop II: results of segregation analyses using POINTER and linkage analyses using LIPED.
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Academic Article
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The allelic architecture of human disease genes: common disease-common variant...or not?
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Academic Article
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Coverage and characteristics of the Affymetrix GeneChip Human Mapping 100K SNP set.
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Academic Article
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Genetic studies of variation in Rayleigh and photometric matches in normal trichromats.
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Academic Article
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Insulin gene mutations as a cause of permanent neonatal diabetes.
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Academic Article
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Polygenic virulence factors involved in pathogenesis of 1997 Hong Kong H5N1 influenza viruses in mice.
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Academic Article
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No bias in linkage analysis.
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Academic Article
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Rational inferences about departures from Hardy-Weinberg equilibrium.
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Academic Article
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The insulin gene and susceptibility to IDDM.
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Academic Article
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Are genome-wide association studies all that we need to dissect the genetic component of complex human diseases?
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Academic Article
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Segregation and linkage analyses of bipolar and major depressive illnesses in multigenerational pedigrees.
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Academic Article
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Lack of association between common single nucleotide polymorphisms in the TERT-CLPTM1L locus and breast cancer in women of African ancestry.
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Academic Article
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Meta-analysis of 23 type 2 diabetes linkage studies from the International Type 2 Diabetes Linkage Analysis Consortium.
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Academic Article
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Mixed effects modeling of proliferation rates in cell-based models: consequence for pharmacogenomics and cancer.
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Academic Article
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The detection of major loci by segregation and linkage analysis: a simulation study.
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Academic Article
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Segregation analysis of speech and language disorders.
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Academic Article
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Restriction fragment polymorphisms of the HLA-DR, HLA-DQ, and insulin gene regions in IDDM: the GAW5 data.
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Academic Article
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Power and sample size calculations for SNP association studies with censored time-to-event outcomes.
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Academic Article
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The 1200 patients project: creating a new medical model system for clinical implementation of pharmacogenomics.
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Academic Article
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Linkage analysis for psychiatric disorders. I. Basic concepts.
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Academic Article
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Lack of significant person-to-person spread of swine influenza-like virus following fatal infection in an immunocompromised child.
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Academic Article
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Variants affecting exon skipping contribute to complex traits.
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Academic Article
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Linkage analysis for psychiatric disorders. II. Methodological considerations.
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Academic Article
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Ascertainment considerations in the analysis of affected sib shared haplotype data.
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Academic Article
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Stuttering: a complex behavioral disorder for our times?
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Academic Article
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Some effects of selection strategies on linkage analysis.
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Academic Article
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Inheritance of human platelet thermolabile phenol sulfotransferase (TL PST) activity.
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Academic Article
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A genome-wide approach to identify genetic variants that contribute to etoposide-induced cytotoxicity.
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Academic Article
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Reconstructability analysis as a tool for identifying gene-gene interactions in studies of human diseases.
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Academic Article
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Germline polymorphisms discovered via a cell-based, genome-wide approach predict platinum response in head and neck cancers.
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Academic Article
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Genetic architecture of microRNA expression: implications for the transcriptome and complex traits.
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Academic Article
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Segregation analyses of stuttering.
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Academic Article
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Characterization of the rat mutant dystonic (dt): a new animal model of dystonia musculorum deformans.
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Academic Article
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The total influenza vaccine failure of 1947 revisited: major intrasubtypic antigenic change can explain failure of vaccine in a post-World War II epidemic.
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Academic Article
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Genetic compatibility and virulence of reassortants derived from contemporary avian H5N1 and human H3N2 influenza A viruses.
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Academic Article
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Lack of transmission of H5N1 avian-human reassortant influenza viruses in a ferret model.
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Academic Article
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Effectiveness of influenza vaccination of day care children in reducing influenza-related morbidity among household contacts.
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Academic Article
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Which patients stop working because of rheumatoid arthritis? Results of five years' follow up in 732 patients from the Early RA Study (ERAS).
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Academic Article
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Mortality associated with influenza and respiratory syncytial virus in the United States.
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Academic Article
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A two-amino acid change in the hemagglutinin of the 1918 influenza virus abolishes transmission.
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Academic Article
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Network models of genome-wide association studies uncover the topological centrality of protein interactions in complex diseases.
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Academic Article
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An exponential combination procedure for set-based association tests in sequencing studies.
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Academic Article
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Comprehensive genetic analysis of cytarabine sensitivity in a cell-based model identifies polymorphisms associated with outcome in AML patients.
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Academic Article
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Pandemic versus epidemic influenza mortality: a pattern of changing age distribution.
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Academic Article
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Genome-wide interrogation of longitudinal FEV1 in children with asthma.
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Academic Article
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Genetic variation is the major determinant of individual differences in leukocyte endothelial adhesion.
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Academic Article
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Poly-omic prediction of complex traits: OmicKriging.
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Academic Article
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Clinical drug response can be predicted using baseline gene expression levels and in vitro drug sensitivity in cell lines.
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Academic Article
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A nondegenerate code of deleterious variants in Mendelian loci contributes to complex disease risk.
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Academic Article
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Use of highly pathogenic avian influenza A(H5N1) gain-of-function studies for molecular-based surveillance and pandemic preparedness.
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Academic Article
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Characterization of drug-resistant influenza A(H7N9) variants isolated from an oseltamivir-treated patient in Taiwan.
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Academic Article
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Pathogenesis, transmissibility, and ocular tropism of a highly pathogenic avian influenza A (H7N3) virus associated with human conjunctivitis.
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Academic Article
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Receptor specificity of influenza A H3N2 viruses isolated in mammalian cells and embryonated chicken eggs.
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Academic Article
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Genome-wide association studies in pharmacogenomics: successes and lessons.
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Academic Article
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A mouse model for the evaluation of pathogenesis and immunity to influenza A (H5N1) viruses isolated from humans.
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Academic Article
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A haplotype-based framework for group-wise transmission/disequilibrium tests for rare variant association analysis.
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Academic Article
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The antigenicity and evolution of influenza H1 haemagglutinin, from 1950-1957 and 1977-1983: two pathways from one gene.
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Academic Article
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The chromosome 3q25 genomic region is associated with measures of adiposity in newborns in a multi-ethnic genome-wide association study.
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Academic Article
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Structural and functional bases for broad-spectrum neutralization of avian and human influenza A viruses.
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Academic Article
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Structural architecture of SNP effects on complex traits.
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Academic Article
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Cross-tissue and tissue-specific eQTLs: partitioning the heritability of a complex trait.
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Academic Article
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Transmission and pathogenesis of swine-origin 2009 A(H1N1) influenza viruses in ferrets and mice.
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Academic Article
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Quantitative allelic test--a fast test for very large association studies.
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Academic Article
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Transformation of a rural community for active living.
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Academic Article
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Identifying plausible genetic models based on association and linkage results: application to type 2 diabetes.
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Academic Article
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Structural stability of influenza A(H1N1)pdm09 virus hemagglutinins.
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Academic Article
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Genetic inactivation of p62 leads to accumulation of hyperphosphorylated tau and neurodegeneration.
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Academic Article
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Characterization of reverse genetics-derived cold-adapted master donor virus A/Leningrad/134/17/57 (H2N2) and reassortants with H5N1 surface genes in a mouse model.
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Academic Article
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Survey of the Heritability and Sparse Architecture of Gene Expression Traits across Human Tissues.
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Academic Article
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Cancer biomarker discovery is improved by accounting for variability in general levels of drug sensitivity in pre-clinical models.
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Academic Article
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Bedside Back to Bench: Building Bridges between Basic and Clinical Genomic Research.
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Academic Article
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Exploring the phenotypic consequences of tissue specific gene expression variation inferred from GWAS summary statistics.
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Academic Article
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Classification of common human diseases derived from shared genetic and environmental determinants.
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Academic Article
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Integrative genetic analysis suggests that skin color modifies the genetic architecture of melanoma.
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Academic Article
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Human Heat shock protein 40 (Hsp40/DnaJB1) promotes influenza A virus replication by assisting nuclear import of viral ribonucleoproteins.
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Academic Article
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LNK deficiency promotes acute aortic dissection and rupture.
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Academic Article
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65 years of influenza surveillance by a World Health Organization-coordinated global network.
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Academic Article
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Relationship between very low low-density lipoprotein cholesterol concentrations not due to statin therapy and risk of type 2 diabetes: A US-based cross-sectional observational study using electronic health records.
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Academic Article
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Gene and MicroRNA Perturbations of Cellular Response to Pemetrexed Implicate Biological Networks and Enable Imputation of Response in Lung Adenocarcinoma.
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Academic Article
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Critical Evaluation of Data Requires Rigorous but Broadly Based Statistical Inference.
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Academic Article
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A Bayesian framework that integrates multi-omics data and gene networks predicts risk genes from schizophrenia GWAS data.
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Academic Article
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Phenome-based approach identifies RIC1-linked Mendelian syndrome through zebrafish models, biobank associations and clinical studies.
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Academic Article
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A Transcriptome-Wide Association Study Identifies Candidate Susceptibility Genes for Pancreatic Cancer Risk.
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Academic Article
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A unified framework for joint-tissue transcriptome-wide association and Mendelian randomization analysis.
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Academic Article
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Three dimensional modeling of biologically relevant fluid shear stress in human renal tubule cells mimics in vivo transcriptional profiles.
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Academic Article
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A transcriptome-wide association study of Alzheimer's disease using prediction models of relevant tissues identifies novel candidate susceptibility genes.
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Academic Article
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Discovery and implications of polygenicity of common diseases.
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Academic Article
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Improving the computation efficiency of polygenic risk score modeling: faster in Julia.
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Concept
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Epidemiological Monitoring
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Academic Article
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Improving polygenic risk prediction in admixed populations by explicitly modeling ancestral-differential effects via GAUDI.
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