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Godley, Lucy
One or more keywords matched the following items that are connected to
Godley, Lucy
Item Type
Name
Concept
Methyltransferases
Concept
DNA (Cytosine-5-)-Methyltransferases
Academic Article
Cancer cells express aberrant DNMT3B transcripts encoding truncated proteins.
Academic Article
A phase I biological study of MG98, an oligodeoxynucleotide antisense to DNA methyltransferase 1, in patients with high-risk myelodysplasia and acute myeloid leukemia.
Academic Article
Coordinated cancer germline antigen promoter and global DNA hypomethylation in ovarian cancer: association with the BORIS/CTCF expression ratio and advanced stage.
Academic Article
DNA methyltransferase 1 and DNA methylation patterning contribute to germinal center B-cell differentiation.
Academic Article
Truncated DNMT3B isoform DNMT3B7 suppresses growth, induces differentiation, and alters DNA methylation in human neuroblastoma.
Academic Article
Molecular biology. Preference by exclusion.
Academic Article
Dnmt3a is essential for hematopoietic stem cell differentiation.
Academic Article
DNMT3B7, a truncated DNMT3B isoform expressed in human tumors, disrupts embryonic development and accelerates lymphomagenesis.
Academic Article
Dnmt3b is a haploinsufficient tumor suppressor gene in Myc-induced lymphomagenesis.
Academic Article
Large conserved domains of low DNA methylation maintained by Dnmt3a.
Academic Article
DNMT3B7 expression promotes tumor progression to a more aggressive phenotype in breast cancer cells.
Academic Article
The mechanistic role of DNA methylation in myeloid leukemogenesis.
Academic Article
5-hydroxymethylcytosine in cancer: significance in diagnosis and therapy.
Academic Article
Epigenetic Control of Apolipoprotein E Expression Mediates Gender-Specific Hematopoietic Regulation.
Academic Article
Increased DNA methylation of Dnmt3b targets impairs leukemogenesis.
Academic Article
Regulation of telomeric function by DNA methylation differs between humans and mice.
Academic Article
RBL2 bi-allelic truncating variants cause severe motor and cognitive impairment without evidence for abnormalities in DNA methylation or telomeric function.
Academic Article
Single-cell multi-omics of human clonal hematopoiesis reveals that DNMT3A R882 mutations perturb early progenitor states through selective hypomethylation.
Grant
The Role of DNMT3B in the DNA Methylation of Cancer Cells
Search Criteria
Methyltransferases