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One or more keywords matched the following items that are connected to Becker, Michael
Item TypeName
Concept Gout
Concept Gout Suppressants
Academic Article Does diuretic use increase the risk of recurrent gout flares?
Academic Article We can make gout management more successful now.
Academic Article Update on emerging urate-lowering therapies.
Academic Article Women with gout: efficacy and safety of urate-lowering with febuxostat and allopurinol.
Academic Article Neurodevelopmental impairment and deranged PRPP and purine nucleotide synthesis in inherited superactivity of PRPP synthetase.
Academic Article Clinical aspects of monosodium urate monohydrate crystal deposition disease (gout).
Academic Article Phosphoribosylpyrophosphate synthetase overactivity as a cause of uric acid overproduction in a young woman.
Academic Article Effects of febuxostat versus allopurinol and placebo in reducing serum urate in subjects with hyperuricemia and gout: a 28-week, phase III, randomized, double-blind, parallel-group trial.
Academic Article Outcome measures for acute and chronic gout.
Academic Article Febuxostat compared with allopurinol in patients with hyperuricemia and gout.
Academic Article Tophaceous gout: quantitative evaluation by direct physical measurement.
Academic Article Compliance with allopurinol therapy among managed care enrollees with gout: a retrospective analysis of administrative claims.
Academic Article Febuxostat, a novel nonpurine selective inhibitor of xanthine oxidase: a twenty-eight-day, multicenter, phase II, randomized, double-blind, placebo-controlled, dose-response clinical trial examining safety and efficacy in patients with gout.
Academic Article The urate-lowering efficacy and safety of febuxostat in the treatment of the hyperuricemia of gout: the CONFIRMS trial.
Academic Article What do I need to know about gout?
Academic Article Tophus measurement as an outcome measure for clinical trials of chronic gout: progress and research priorities.
Academic Article Serum urate in chronic gout--will it be the first validated soluble biomarker in rheumatology?
Academic Article Efficacy and tolerability of pegloticase for the treatment of chronic gout in patients refractory to conventional treatment: two randomized controlled trials.
Academic Article Reduction of plasma urate levels following treatment with multiple doses of pegloticase (polyethylene glycol-conjugated uricase) in patients with treatment-failure gout: results of a phase II randomized study.
Academic Article Clinical efficacy and safety of successful longterm urate lowering with febuxostat or allopurinol in subjects with gout.
Academic Article Quality of life and disability in patients with treatment-failure gout.
Academic Article Patient-reported outcomes in chronic gout: a report from OMERACT 10.
Academic Article Treating hyperuricemia of gout: safety and efficacy of febuxostat and allopurinol in older versus younger subjects.
Academic Article Inherited superactivity of phosphoribosylpyrophosphate synthetase: association of uric acid overproduction and sensorineural deafness.
Academic Article Outcome evaluations in gout.
Academic Article Determinants of the clinical outcomes of gout during the first year of urate-lowering therapy.
Academic Article Bringing it all together: a novel approach to the development of response criteria for chronic gout clinical trials.
Academic Article Urate transporters: transforming the face of hyperuricemia and gout.
Academic Article Diabetes and gout: efficacy and safety of febuxostat and allopurinol.
Academic Article Infusion-related reactions with pegloticase, a recombinant uricase for the treatment of chronic gout refractory to conventional therapy.
Academic Article Tophus burden reduction with pegloticase: results from phase 3 randomized trials and open-label extension in patients with chronic gout refractory to conventional therapy.
Academic Article Long-term management of gout: nonpharmacologic and pharmacologic therapies.
Academic Article Pegloticase immunogenicity: the relationship between efficacy and antibody development in patients treated for refractory chronic gout.
Academic Article Long-term safety of pegloticase in chronic gout refractory to conventional treatment.
Academic Article An open-label, 6-month study of allopurinol safety in gout: The LASSO study.
Academic Article Impact of Febuxostat on Renal Function in Gout Patients With Moderate-to-Severe Renal Impairment.
Academic Article Summary of the 2015 Purine and Pyrimidine Society/Purine Metabolic Patients Association H. Anne Simmonds Memorial Lecture.
Academic Article Lesinurad Combined With Allopurinol: A Randomized, Double-Blind, Placebo-Controlled Study in Gout Patients With an Inadequate Response to Standard-of-Care Allopurinol (a US-Based Study).
Academic Article Genetic aspects of gout.
Academic Article Identification of distinct PRS1 mutations in two patients with X-linked phosphoribosylpyrophosphate synthetase superactivity.
Academic Article Increased PP-ribose-P synthetase activity: a genetic abnormality leading to excessive purine production and gout.
Academic Article Recent advances in the identification of enzyme abnormalities underlying excessive purine synthesis in man.
Academic Article Rheumatology.
Academic Article A modified Delphi exercise to determine the extent of consensus with OMERACT outcome domains for studies of acute and chronic gout.
Academic Article Gout with purine overproduction due to increased phosphoribosylpyrophosphate synthetase activity.
Academic Article Human phosphoribosylpyrophosphate synthetase: increased enzyme specific activity in a family with gout and excessive purine synthesis.
Academic Article Efficacy and safety of febuxostat extended release and immediate release in patients with gout and moderate renal impairment: phase II placebo-controlled study.
Academic Article Febuxostat in the treatment of gout: 5-yr findings of the FOCUS efficacy and safety study.
Academic Article Diminished affinity for purine substrates as a basis for gout with mild deficiency of hypoxanthine-guanine phosphoribosyltransferase.
Academic Article A revised estimate of the burden of illness of gout.
Academic Article Inflammation: a possible mechanism for a causative role of hyperuricemia/gout in cardiovascular disease.
Academic Article Magnetic resonance imaging in the quantitative assessment of gouty tophi.
Academic Article Cardiovascular Safety of Febuxostat or Allopurinol in Patients with Gout.
Academic Article Gout with superactive phosphoribosylpyrophosphate synthetase due to increased enzyme catalytic rate.
Academic Article Diagnostic evaluation of phosphoribosylpyrophosphate synthetase activities in hemolysates.
Academic Article Purine overproduction in man associated with increased phosphoribosylpyrophosphate synthetase activity.
Academic Article Evaluation of the role of 5-phosphoribosyl-alpha-1-pyrophosphate synthetase in congenital hyperuricemia and gout: a simple isotopic assay and an activity stain for the enzyme.
Academic Article Patterns of phosphoribosylpyrophosphate and ribose-5-phosphate concentration and generation in fibroblasts from patients with gout and purine overproduction.
Academic Article Fibroblast phosphoribosylpyrophosphate and ribose-5-phosphate concentration and generation in gout with purine overproduction.
Academic Article Work productivity loss due to flares in patients with chronic gout refractory to conventional therapy.
Academic Article Efficacy and Safety of Febuxostat Extended and Immediate Release in Patients With Gout and Renal Impairment: A Phase III Placebo-Controlled Study.
Academic Article Evaluation of the Relationship Between Serum Urate Levels, Clinical Manifestations of Gout, and Death From Cardiovascular Causes in Patients Receiving Febuxostat or Allopurinol in an Outcomes Trial.
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  • Gout