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Concept
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Chromosomes, Human, Pair 2
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Concept
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Chromosomes, Human, Pair 6
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Concept
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Chromosomes, Human, Pair 1
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Concept
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Chromosomes, Human, Pair 13
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Concept
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Chromosomes, Human, Pair 4
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Concept
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Chromosomes, Human, Pair 5
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Concept
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Chromosomes, Human, Pair 7
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Concept
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Chromosomes, Human, Pair 17
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Concept
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Chromosomes, Human, Pair 19
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Concept
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Chromosomes, Human, Pair 9
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Concept
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Herpesvirus 4, Human
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Concept
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Humans
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Concept
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Human Body
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Concept
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Genome, Human
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Concept
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Pheromones, Human
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Concept
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Chromosomes, Human
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Concept
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Chromosomes, Human, Pair 16
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Concept
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Chromosomes, Human, X
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Concept
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Chromosomes, Human, Y
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Academic Article
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Mononuclear-cell immunisation in prevention of recurrent miscarriages: a randomised trial.
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Academic Article
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Transmission disequilibrium of maternally-inherited CTLA-4 microsatellite alleles in idiopathic recurrent miscarriage.
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Academic Article
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HLA-G1 protein expression is not essential for fetal survival.
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Academic Article
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Broad and narrow heritabilities of quantitative traits in a founder population.
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Academic Article
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Paternally inherited HLA alleles are associated with women's choice of male odor.
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Academic Article
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Quantitative-trait homozygosity and association mapping and empirical genomewide significance in large, complex pedigrees: fasting serum-insulin level in the Hutterites.
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Academic Article
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A null mutation in HLA-G is not associated with preeclampsia or intrauterine growth retardation.
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Academic Article
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A second-generation genomewide screen for asthma-susceptibility alleles in a founder population.
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Academic Article
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Novel case-control test in a founder population identifies P-selectin as an atopy-susceptibility locus.
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Academic Article
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Variation in the HLA-G promoter region influences miscarriage rates.
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Academic Article
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Sequence variation in the promoter region of the cholinergic receptor muscarinic 3 gene and asthma and atopy.
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Academic Article
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Are common disease susceptibility alleles the same in outbred and founder populations?
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Academic Article
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Genetic variation in immunoregulatory pathways and atopic phenotypes in infancy.
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Academic Article
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Genome-wide association study identifies ITGB3 as a QTL for whole blood serotonin.
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Academic Article
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The genetic dissection of complex traits in a founder population.
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Academic Article
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Linkage disequilibrium and age estimates of a deletion polymorphism (1597DeltaC) in HLA-G suggest non-neutral evolution.
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Academic Article
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Human body scents: conscious perceptions and biological effects.
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Academic Article
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Sex-specific genetic architecture of whole blood serotonin levels.
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Academic Article
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Multilocus linkage disequilibrium mapping by the decay of haplotype sharing with samples of related individuals.
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Academic Article
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Cutting edge: polymorphisms in the ICOS promoter region are associated with allergic sensitization and Th2 cytokine production.
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Academic Article
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ITGB3 shows genetic and expression interaction with SLC6A4.
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Academic Article
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Evidence of balancing selection at the HLA-G promoter region.
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Academic Article
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Does HLA-dependent chimerism underlie the pathogenesis of juvenile dermatomyositis?
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Academic Article
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Heritability estimation of sex-specific effects on human quantitative traits.
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Academic Article
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Correlation of intergenerational family sizes suggests a genetic component of reproductive fitness.
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Academic Article
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High-resolution mapping of crossovers reveals extensive variation in fine-scale recombination patterns among humans.
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Academic Article
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Best linear unbiased allele-frequency estimation in complex pedigrees.
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Academic Article
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Effects of dog ownership and genotype on immune development and atopy in infancy.
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Academic Article
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Sex-specific genetic architecture of human disease.
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Academic Article
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CFTR mutations and reproductive outcomes in a population isolate.
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Academic Article
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Variation in ITGB3 has sex-specific associations with plasma lipoprotein(a) and whole blood serotonin levels in a population-based sample.
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Academic Article
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Drawing the history of the Hutterite population on a genetic landscape: inference from Y-chromosome and mtDNA genotypes.
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Academic Article
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Genome-wide association study of plasma lipoprotein(a) levels identifies multiple genes on chromosome 6q.
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Academic Article
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Colloquium papers: Heritability of reproductive fitness traits in a human population.
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Academic Article
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Sequencing the IL4 locus in African Americans implicates rare noncoding variants in asthma susceptibility.
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Academic Article
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HLA-G and immune tolerance in pregnancy.
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Academic Article
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Shades of gray: a comparison of linkage disequilibrium between Hutterites and Europeans.
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Academic Article
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The sex-specific genetic architecture of quantitative traits in humans.
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Academic Article
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Fine mapping and positional candidate studies on chromosome 5p13 identify multiple asthma susceptibility loci.
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Academic Article
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Gene-environment interactions in human disease: nuisance or opportunity?
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Academic Article
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Allele-specific targeting of microRNAs to HLA-G and risk of asthma.
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Academic Article
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Integrin beta 3 genotype influences asthma and allergy phenotypes in the first 6 years of life.
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Academic Article
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The genetics of asthma and allergic disease: a 21st century perspective.
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Academic Article
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The effects of EBV transformation on gene expression levels and methylation profiles.
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Academic Article
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IFNG genotype and sex interact to influence the risk of childhood asthma.
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Academic Article
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Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations.
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Academic Article
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Accurate imputation of rare and common variants in a founder population from a small number of sequenced individuals.
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Academic Article
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Genome-wide ancestry association testing identifies a common European variant on 6q14.1 as a risk factor for asthma in African American subjects.
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Academic Article
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Genetic analysis of HLA in the U.S. Schmiedenleut Hutterites.
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Academic Article
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Increased protein-coding mutations in the mitochondrial genome of African American women with preeclampsia.
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Academic Article
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Estimating the human mutation rate using autozygosity in a founder population.
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Academic Article
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Genome-wide association studies of asthma indicate opposite immunopathogenesis direction from autoimmune diseases.
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Academic Article
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Adverse effects of human leukocyte antigen-DR sharing on fertility: a cohort study in a human isolate.
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Academic Article
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The combination of a genome-wide association study of lymphocyte count and analysis of gene expression data reveals novel asthma candidate genes.
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Academic Article
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Variation in conserved non-coding sequences on chromosome 5q and susceptibility to asthma and atopy.
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Academic Article
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Evaluating the evidence for transmission distortion in human pedigrees.
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Academic Article
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Sex-specific genetic architecture of asthma-associated quantitative trait loci in a founder population.
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Academic Article
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Rising prevalence of asthma is sex-specific in a US farming population.
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Academic Article
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Genome-wide association study identifies candidate genes for male fertility traits in humans.
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Academic Article
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Variation in ITGB3 is associated with whole-blood serotonin level and autism susceptibility.
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Academic Article
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Resequencing candidate genes implicates rare variants in asthma susceptibility.
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Academic Article
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HLA-DQA1 and HLA-DQB1 haplotypes in aborted fetuses and couples with recurrent spontaneous abortion.
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Academic Article
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MHC class II compatibility in aborted fetuses and term infants of couples with recurrent spontaneous abortion.
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Academic Article
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Effect of variation in CHI3L1 on serum YKL-40 level, risk of asthma, and lung function.
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Academic Article
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Sequence variations at the human leukocyte antigen-linked olfactory receptor cluster do not influence female preferences for male odors.
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Academic Article
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Exome sequencing reveals a novel mutation for autosomal recessive non-syndromic mental retardation in the TECR gene on chromosome 19p13.
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Academic Article
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A population-based study of autosomal-recessive disease-causing mutations in a founder population.
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Academic Article
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Shared HLA antigens and reproductive performance among Hutterites.
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Academic Article
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HLA and mate choice in humans.
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Academic Article
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Estimation of variance components of quantitative traits in inbred populations.
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Academic Article
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Major loci influencing serum triglyceride levels on 2q14 and 9p21 localized by homozygosity-by-descent mapping in a large Hutterite pedigree.
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Academic Article
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Evidence for extensive transmission distortion in the human genome.
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Academic Article
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Association studies for asthma and atopic diseases: a comprehensive review of the literature.
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Academic Article
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Fine mapping and positional candidate studies identify HLA-G as an asthma susceptibility gene on chromosome 6p21.
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Academic Article
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Gene-environment interaction effects on the development of immune responses in the 1st year of life.
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Academic Article
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Variation in ITGB3 is associated with asthma and sensitization to mold allergen in four populations.
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Academic Article
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Rethinking genetic models of asthma: the role of environmental modifiers.
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Academic Article
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A genome-wide screen for hyposmia susceptibility Loci.
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Academic Article
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Fine mapping of a locus for nonsyndromic mental retardation on chromosome 19p13.
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Academic Article
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A genomewide screen for chronic rhinosinusitis genes identifies a locus on chromosome 7q.
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Academic Article
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The CFTR Met 470 allele is associated with lower birth rates in fertile men from a population isolate.
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Academic Article
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A common spinal muscular atrophy deletion mutation is present on a single founder haplotype in the US Hutterites.
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Academic Article
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Further replication studies of the EVE Consortium meta-analysis identifies 2 asthma risk loci in European Americans.
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Academic Article
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Low fetal loss rates after ultrasound-proved viability in early pregnancy.
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Academic Article
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The miscarriage-associated HLA-G -725G allele influences transcription rates in JEG-3 cells.
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Academic Article
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HLA-G genotypes and pregnancy outcome in couples with unexplained recurrent miscarriage.
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Academic Article
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Maternal microchimerism protects against the development of asthma.
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Academic Article
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Rhinovirus wheezing illness and genetic risk of childhood-onset asthma.
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Academic Article
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The maternal HLA-G 1597?C null mutation is associated with increased risk of pre-eclampsia and reduced HLA-G expression during pregnancy in African-American women.
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Academic Article
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A meta-analysis of genome-wide association studies for serum total IgE in diverse study populations.
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Academic Article
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Maternal asthma and microRNA regulation of soluble HLA-G in the airway.
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Academic Article
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The CTLA-4 gene is expressed in placental fibroblasts.
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Academic Article
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Inbreeding effects on fertility in humans: evidence for reproductive compensation.
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Academic Article
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Genome-wide interaction studies reveal sex-specific asthma risk alleles.
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Academic Article
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Effect of inbreeding avoidance on Hardy-Weinberg expectations: examples of neutral and selected loci.
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Academic Article
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HLA and pregnancy: the paradox of the fetal allograft.
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Academic Article
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HLA-G polymorphisms: neutral evolution or novel function?
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Academic Article
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Population genetic studies of HLA-E: evidence for selection.
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Academic Article
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Population genetic studies of HLA-G: allele frequencies and linkage disequilibrium with HLA-A1.
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Academic Article
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Human leukocyte antigen matching and fetal loss: results of a 10 year prospective study.
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Academic Article
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Whole-genome sequencing of individuals from a founder population identifies candidate genes for asthma.
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Academic Article
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The effect of freeze-thaw cycles on gene expression levels in lymphoblastoid cell lines.
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Academic Article
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An estimate of the average number of recessive lethal mutations carried by humans.
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Academic Article
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Evolutionary forward genomics reveals novel insights into the genes and pathways dysregulated in recurrent early pregnancy loss.
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Academic Article
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PRIMAL: Fast and accurate pedigree-based imputation from sequence data in a founder population.
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Academic Article
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Seasonal variation in human gut microbiome composition.
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Academic Article
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Genome-wide association study of lung function phenotypes in a founder population.
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Academic Article
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Host genetic variation influences gene expression response to rhinovirus infection.
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Academic Article
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Ethnic-specific associations of rare and low-frequency DNA sequence variants with asthma.
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Academic Article
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Genome-Wide Association Studies of the Human Gut Microbiota.
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Academic Article
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Genome-Wide Methylation Study Identifies an IL-13-induced Epigenetic Signature in Asthmatic Airways.
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Academic Article
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Leveraging gene-environment interactions and endotypes for asthma gene discovery.
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Academic Article
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Asthma Genetics in the Post-GWAS Era.
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Academic Article
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Expression Quantitative Trait Locus Mapping Studies in Mid-secretory Phase Endometrial Cells Identifies HLA-F and TAP2 as Fecundability-Associated Genes.
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Academic Article
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Innate Immunity and Asthma Risk in Amish and Hutterite Farm Children.
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Academic Article
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Integrated analyses of gene expression and genetic association studies in a founder population.
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Academic Article
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DNA methylation in lung cells is associated with asthma endotypes and genetic risk.
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Academic Article
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Host genetic variation in mucosal immunity pathways influences the upper airway microbiome.
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Academic Article
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Rare non-coding variants are associated with plasma lipid traits in a founder population.
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Academic Article
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A decade of research on the 17q12-21 asthma locus: Piecing together the puzzle.
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Academic Article
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Parent of origin gene expression in a founder population identifies two new candidate imprinted genes at known imprinted regions.
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Academic Article
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Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.
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Academic Article
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Effects of an Fc?RIIA polymorphism on leukocyte gene expression and cytokine responses to anti-CD3 and anti-CD28 antibodies.
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Academic Article
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Immune development and environment: lessons from Amish and Hutterite children.
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Academic Article
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Global DNA methylation changes spanning puberty are near predicted estrogen-responsive genes and enriched for genes involved in endocrine and immune processes.
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Academic Article
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Parent-of-origin effects on quantitative phenotypes in a large Hutterite pedigree.
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Academic Article
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Shared and distinct genetic risk factors for childhood-onset and adult-onset asthma: genome-wide and transcriptome-wide studies.
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Academic Article
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Associations between fungal and bacterial microbiota of airways and asthma endotypes.
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Academic Article
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T-cell phenotypes are associated with serum IgE levels in Amish and Hutterite children.
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Academic Article
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Associations of autozygosity with a broad range of human phenotypes.
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Academic Article
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Advances in asthma and allergic disease genetics: Is bigger always better?
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Academic Article
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Transcriptional programming and T cell receptor repertoires distinguish human lung and lymph node memory T cells.
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Academic Article
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Transcriptional programming and T cell receptor repertoires distinguish human lung and lymph node memory T cells.
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Academic Article
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Association of HLA-DRB1*09:01 with tIgE levels among African-ancestry individuals with asthma.
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Academic Article
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Club Cell TRPV4 Serves as a Damage Sensor Driving Lung Allergic Inflammation.
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Academic Article
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Association of respiratory allergy, asthma, and expression of the SARS-CoV-2 receptor ACE2.
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Academic Article
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Expression quantitative trait locus fine mapping of the 17q12-21 asthma locus in African American children: a genetic association and gene expression study.
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Academic Article
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Epigenome-wide association study of DNA methylation and adult asthma in the Agricultural Lung Health Study.
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Academic Article
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Epigenetic landscape links upper airway microbiota in infancy with allergic rhinitis at 6 years of age.
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Academic Article
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Cytokine-induced molecular responses in airway smooth muscle cells inform genome-wide association studies of asthma.
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Academic Article
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Altered transcriptional and chromatin responses to rhinovirus in bronchial epithelial cells from adults with asthma.
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Academic Article
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Transcriptome and regulatory maps of decidua-derived stromal cells inform gene discovery in preterm birth.
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Academic Article
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FUT2-ABO epistasis increases the risk of early childhood asthma and Streptococcus pneumoniae respiratory illnesses.
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Academic Article
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Two-stage genome-wide association study of chronic rhinosinusitis and disease subphenotypes highlights mucosal immunity contributing to risk.
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Academic Article
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Sex-specific differences in peripheral blood leukocyte transcriptional response to LPS are enriched for HLA region and X chromosome genes.
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Academic Article
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A-to-I editing of miR-200b-3p in airway cells is associated with moderate-to-severe asthma.
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Academic Article
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Longitudinal data reveal strong genetic and weak non-genetic components of ethnicity-dependent blood DNA methylation levels.
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Academic Article
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Chromosome 17q12-21 Variants Are Associated with Multiple Wheezing Phenotypes in Childhood.
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Academic Article
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Genome-wide association study identifies TNFSF15 associated with childhood asthma.
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Academic Article
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Extensive pleiotropism and allelic heterogeneity mediate metabolic effects of IRX3 and IRX5.
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Academic Article
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Establishment of human induced trophoblast stem-like cells from term villous cytotrophoblasts.
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Academic Article
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A functional genomics pipeline identifies pleiotropy and cross-tissue effects within obesity-associated GWAS loci.
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Academic Article
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Multiethnic genome-wide and HLA association study of total serum IgE level.
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Academic Article
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Multi-omics colocalization with genome-wide association studies reveals a context-specific genetic mechanism at a childhood onset asthma risk locus.
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Academic Article
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Asthma-associated genetic variants induce IL33 differential expression through an enhancer-blocking regulatory region.
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Academic Article
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Inducible expression quantitative trait locus analysis of the MUC5AC gene in asthma in urban populations of children.
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Academic Article
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Genome-wide study of early and severe childhood asthma identifies interaction between CDHR3 and GSDMB.
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Academic Article
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New Insights Relating Gasdermin B to the Onset of Childhood Asthma.
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Academic Article
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Fine-mapping studies distinguish genetic risks for childhood- and adult-onset asthma in the HLA region.
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Academic Article
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DNA methylation signatures in airway cells from adult children of asthmatic mothers reflect subtypes of severe asthma.
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Academic Article
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African-specific alleles modify risk for asthma at the 17q12-q21 locus in African Americans.
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Academic Article
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Discerning asthma endotypes through comorbidity mapping.
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Academic Article
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Multi-omic association study identifies DNA methylation-mediated genotype and smoking exposure effects on lung function in children living in urban settings.
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Academic Article
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A functional genomics pipeline to identify high-value asthma and allergy CpGs in the human methylome.
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Grant
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Airway inflammation and HLA-G in asthma
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