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Concept
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Rats, Inbred SHR
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Concept
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Rats, Inbred F344
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Concept
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Rats, Inbred WKY
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Concept
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Rats, Sprague-Dawley
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Concept
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Rats, Wistar
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Concept
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Rats, Inbred Strains
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Concept
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Rats
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Academic Article
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Long-term elevation of cyclooxygenase-2, but not lipoxygenase, in regions synaptically distant from spreading depression.
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Academic Article
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Neocortical spreading depression provokes the expression of c-fos protein-like immunoreactivity within trigeminal nucleus caudalis via trigeminovascular mechanisms.
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Academic Article
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Whole-cell chloride currents in rat astrocytes accompany changes in cell morphology.
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Academic Article
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Eicosanoids and nitric oxide influence induction of reactive gliosis from spreading depression in microglia but not astrocytes.
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Academic Article
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Cytoskeletal actin gates a Cl- channel in neocortical astrocytes.
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Academic Article
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Comment on Ingvardsen et al., PAIN, 72 (1997) 407-415.
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Academic Article
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Reactive astrocytosis from excitotoxic injury in hippocampal organ culture parallels that seen in vivo.
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Academic Article
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Prostaglandin E receptor subtypes in cultured rat microglia and their role in reducing lipopolysaccharide-induced interleukin-1beta production.
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Academic Article
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Neuronal nitric oxide synthase expression is induced in neocortical astrocytes after spreading depression.
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Academic Article
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Calcium waves precede electrophysiological changes of spreading depression in hippocampal organ cultures.
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Academic Article
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Prostaglandin E2 and 4-aminopyridine prevent the lipopolysaccharide-induced outwardly rectifying potassium current and interleukin-1beta production in cultured rat microglia.
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Academic Article
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Carbonic acid buffer species measured in real time with an intracellular microelectrode array.
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Academic Article
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Hippocampal spreading depression bilaterally activates the caudal trigeminal nucleus in rodents.
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Academic Article
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Intracellular pH rises and astrocytes swell after portacaval anastomosis in rats.
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Academic Article
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Spreading depression increases immunohistochemical staining of glial fibrillary acidic protein.
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Academic Article
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Homeostatic plasticity in hippocampal slice cultures involves changes in voltage-gated Na+ channel expression.
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Academic Article
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Optimization of multiplexed bead-based cytokine immunoassays for rat serum and brain tissue.
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Academic Article
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Optical current source density analysis in hippocampal organotypic culture shows that spreading depression occurs with uniquely reversing currents.
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Academic Article
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Ionic concomitants of astroglial transformation to reactive species.
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Academic Article
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Astrocytic acidosis in hyperglycemic and complete ischemia.
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Academic Article
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Cold pre-conditioning neuroprotection depends on TNF-a and is enhanced by blockade of interleukin-11.
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Academic Article
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Spreading depression sends microglia on Lévy flights.
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Academic Article
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Enhanced integrated stress response promotes myelinating oligodendrocyte survival in response to interferon-gamma.
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Academic Article
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Differential effects of low-dose endotoxin on the cerebral circulation during pregnancy.
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Academic Article
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Compartmentation of acid-base balance in brain during complete ischemia.
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Academic Article
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Pregnant serum induces neuroinflammation and seizure activity via TNFa.
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Academic Article
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Carbonic acid buffer changes during complete brain ischemia.
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Academic Article
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Strategies for study of neuroprotection from cold-preconditioning.
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Academic Article
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Insulin-like growth factor-1 lowers spreading depression susceptibility and reduces oxidative stress.
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Academic Article
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Hydrogen ion buffering during complete brain ischemia.
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Academic Article
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Bicarbonate and ammonia changes in brain during spreading depression.
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Academic Article
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Acid-induced changes of brain protein buffering.
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Academic Article
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Hydrogen ions kill brain at concentrations reached in ischemia.
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Academic Article
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The effects of extracellular acidosis on neurons and glia in vitro.
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Academic Article
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Characterization of inducible cyclooxygenase in rat brain.
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Academic Article
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Potassium, calcium, chloride and sodium changes in extracellular space during spreading depression in cerebellum [proceedings].
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Academic Article
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Monomeric IgG is neuroprotective via enhancing microglial recycling endocytosis and TNF-alpha.
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Academic Article
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Alkaline and acid transients in cerebellar microenvironment.
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Academic Article
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Light and electron microscopic evaluation of hydrogen ion-induced brain necrosis.
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Academic Article
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Intracellular pH of astrocytes increases rapidly with cortical stimulation.
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Academic Article
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In vivo measurement of regional brain and tumor pH using [14C]dimethyloxazolidinedione and quantitative autoradiography. II: Characterization of the extracellular fluid compartment using pH-sensitive microelectrodes and [14C]sucrose.
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Academic Article
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Focal elevations in neocortical interstitial K+ produced by stimulation of the fastigial nucleus in rat.
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Academic Article
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Dynamics of interstitial and intracellular pH in evolving brain infarct.
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Academic Article
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Intracellular pH transients of mammalian astrocytes.
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Academic Article
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Determination of extracellular bicarbonate and carbon dioxide concentrations in brain slices using carbonate and pH-selective microelectrodes.
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Academic Article
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Nanoparticle targeting to neurons in a rat hippocampal slice culture model.
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Academic Article
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Insulin-like growth factor-1 abrogates microglial oxidative stress and TNF-a responses to spreading depression.
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Academic Article
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IFN?-stimulated dendritic cell exosomes as a potential therapeutic for remyelination.
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Academic Article
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Youth and environmental enrichment generate serum exosomes containing miR-219 that promote CNS myelination.
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Academic Article
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Spreading depression requires microglia and is decreased by their M2a polarization from environmental enrichment.
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Academic Article
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Spreading depression transiently disrupts myelin via interferon-gamma signaling.
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Academic Article
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Phasic Treatment with Interferon Gamma Stimulates Release of Exosomes that Protect Against Spreading Depression.
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Academic Article
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Environmental Enrichment Stimulates Immune Cell Secretion of Exosomes that Promote CNS Myelination and May Regulate Inflammation.
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Academic Article
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Intranasally administered IGF-1 inhibits spreading depression in vivo.
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Academic Article
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Insulin-like growth factor-1 inhibits spreading depression-induced trigeminal calcitonin gene related peptide, oxidative stress & neuronal activation in rat.
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Academic Article
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Insulin-like growth factor-1 inhibits nitroglycerin-induced trigeminal activation of oxidative stress, calcitonin gene-related peptide and c-Fos expression.
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Academic Article
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IFN?-stimulated dendritic cell extracellular vesicles can be nasally administered to the brain and enter oligodendrocytes.
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Grant
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Exosome RNA-Therapeutics to Promote CNS Myelination
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Grant
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Environment Enrichment, Neuroprotection and Spreading Depression
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Grant
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Exosome RNA-Therapeutics to Promote CNS Myelination
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Grant
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Development of Nasal IGF-1 as a Migraine Therapeutic
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