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One or more keywords matched the following items that are connected to Gajewski, Thomas F.
Item TypeName
Concept Interleukin-2
Concept Interleukin-1
Concept Interleukin-3
Concept Interleukin-6
Concept Receptors, Interleukin-6
Concept Receptors, Interleukin-2
Concept Interleukin-4
Concept Interleukin-12
Concept Interleukin-23
Concept Interleukin-23 Subunit p19
Academic Article B7-1 but not B7-2 efficiently costimulates CD8+ T lymphocytes in the P815 tumor system in vitro.
Academic Article Liver of MRL/lpr mice contain interleukin-4-producing lymphocytes and accessory cells that support the proliferation of Th2 helper T lymphocyte clones.
Academic Article Endogenous IL-12 is necessary for rejection of P815 tumor variants in vivo.
Academic Article Antigen-specific regression of established tumors induced by active immunization with irradiated IL-12- but not B7-1-transfected tumor cells.
Academic Article Blocked Ras activation in anergic CD4+ T cells.
Academic Article Interleukin-12-secreting human papillomavirus type 16-transformed cells provide a potent cancer vaccine that generates E7-directed immunity.
Academic Article Cutting edge: differentiation of antitumor CTL in vivo requires host expression of Stat1.
Academic Article CD28 is not required for c-Jun N-terminal kinase activation in T cells.
Academic Article Improved efficacy of dendritic cell vaccines and successful immunization with tumor antigen peptide-pulsed peripheral blood mononuclear cells by coadministration of recombinant murine interleukin-12.
Academic Article Flt-3 ligand and sequential FL/interleukin-2 in patients with metastatic renal carcinoma: clinical and biologic activity.
Academic Article Immunization of HLA-A2+ melanoma patients with MAGE-3 or MelanA peptide-pulsed autologous peripheral blood mononuclear cells plus recombinant human interleukin 12.
Academic Article Cutting edge: spontaneous rejection of poorly immunogenic P1.HTR tumors by Stat6-deficient mice.
Academic Article Immunization with Melan-A peptide-pulsed peripheral blood mononuclear cells plus recombinant human interleukin-12 induces clinical activity and T-cell responses in advanced melanoma.
Academic Article Integrating IL-12 into therapeutic cancer vaccines.
Academic Article Epitope spreading upon P815 tumor rejection triggered by vaccination with the single class I MHC-restricted peptide P1A.
Academic Article Differential Ras signaling via the antigen receptor and IL-2 receptor in primary T lymphocytes.
Academic Article Actin cytoskeleton regulates calcium dynamics and NFAT nuclear duration.
Academic Article Depletion of normal B cells with rituximab as an adjunct to IL-2 therapy for renal cell carcinoma and melanoma.
Academic Article CD4+ murine T cell clones that express high levels of immunoglobulin binding belong to the interleukin 4-producing T helper cell type 2 subset.
Academic Article Murine Th1 and Th2 clones proliferate optimally in response to distinct antigen-presenting cell populations.
Academic Article Phase 2 study of the g209-2M melanoma peptide vaccine and low-dose interleukin-2 in advanced melanoma: Cancer and Leukemia Group B 509901.
Academic Article Evidence implicating utilization of different T cell receptor-associated signaling pathways by TH1 and TH2 clones.
Academic Article Tumor progression despite massive influx of activated CD8(+) T cells in a patient with malignant melanoma ascites.
Academic Article The HLA-A2-restricted PSMA peptide LLHETDSAV is poorly immunogenic in patients with metastatic prostate cancer.
Academic Article Anti-proliferative effect of IFN-gamma in immune regulation. IV. Murine CTL clones produce IL-3 and GM-CSF, the activity of which is masked by the inhibitory action of secreted IFN-gamma.
Academic Article A randomized phase II trial of interleukin-2 in combination with four different doses of bryostatin-1 in patients with renal cell carcinoma.
Academic Article Cross-priming of T cells to intracranial tumor antigens elicits an immune response that fails in the effector phase but can be augmented with local immunotherapy.
Academic Article Evidence implicating the Ras pathway in multiple CD28 costimulatory functions in CD4+ T cells.
Academic Article Nakahara memorial lecture. Regulation of T lymphocyte responses: interactions among receptors.
Academic Article Glucose availability regulates IFN-gamma production and p70S6 kinase activation in CD8+ effector T cells.
Academic Article Regulation of T-cell activation: differences among T-cell subsets.
Academic Article An adenoviral vector for probing promoter activity in primary immune cells.
Academic Article Costimulation with B7-1, IL-6, and IL-12 is sufficient for primary generation of murine antitumor cytolytic T lymphocytes in vitro.
Academic Article Anti-proliferative effect of IFN-gamma in immune regulation. I. IFN-gamma inhibits the proliferation of Th2 but not Th1 murine helper T lymphocyte clones.
Academic Article Differential activation of Th1 and Th2 CD4+ cells by murine brain microvessel endothelial cells and smooth muscle/pericytes.
Academic Article Anergic T-lymphocyte clones have altered inositol phosphate, calcium, and tyrosine kinase signaling pathways.
Academic Article An adenoviral vector encoding dominant negative Cbl lowers the threshold for T cell activation in post-thymic T cells.
Academic Article "Anergy" of TH0 helper T lymphocytes induces downregulation of TH1 characteristics and a transition to a TH2-like phenotype.
Academic Article Anti-proliferative effect of IFN-gamma in immune regulation. II. IFN-gamma inhibits the proliferation of murine bone marrow cells stimulated with IL-3, IL-4, or granulocyte-macrophage colony-stimulating factor.
Academic Article Interleukin 2 and concanavalin A stimulate interferon-gamma production in a murine cytolytic T cell clone by different pathways.
Academic Article Control of T lymphocyte signal transduction through clonal anergy.
Academic Article A phase II study of bryostatin-1 and paclitaxel in patients with advanced non-small cell lung cancer.
Academic Article Formation of a central supramolecular activation cluster is not required for activation of naive CD8+ T cells.
Academic Article Farnesyltransferase inhibitors inhibit T-cell cytokine production at the posttranscriptional level.
Academic Article Antiproliferative effect of IFN-gamma in immune regulation. III. Differential selection of TH1 and TH2 murine helper T lymphocyte clones using recombinant IL-2 and recombinant IFN-gamma.
Academic Article Phase II study of immunomodulation with granulocyte-macrophage colony-stimulating factor, interleukin-2, and rituximab following autologous stem cell transplant in patients with relapsed or refractory lymphomas.
Academic Article Phase II study of the Src kinase inhibitor saracatinib (AZD0530) in metastatic melanoma.
Academic Article Mechanism of tumor rejection with doublets of CTLA-4, PD-1/PD-L1, or IDO blockade involves restored IL-2 production and proliferation of CD8(+) T cells directly within the tumor microenvironment.
Academic Article The EGR2 targets LAG-3 and 4-1BB describe and regulate dysfunctional antigen-specific CD8+ T cells in the tumor microenvironment.
Academic Article Secondary resistance to immunotherapy associated with ?-catenin pathway activation or PTEN loss in metastatic melanoma.
Academic Article Insights from immuno-oncology: the Society for Immunotherapy of Cancer Statement on access to IL-6-targeting therapies for COVID-19.
Academic Article COVIDOSE: A Phase II Clinical Trial of Low-Dose Tocilizumab in the Treatment of Noncritical COVID-19 Pneumonia.
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