"Interleukin-4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A soluble factor produced by activated T-LYMPHOCYTES that induces the expression of MHC CLASS II GENES and FC RECEPTORS on B-LYMPHOCYTES and causes their proliferation and differentiation. It also acts on T-lymphocytes, MAST CELLS, and several other hematopoietic lineage cells.
| Descriptor ID |
D015847
|
| MeSH Number(s) |
D12.644.276.374.465.186 D12.776.467.374.465.178 D23.529.374.465.186
|
| Concept/Terms |
Interleukin-4- Interleukin-4
- Interleukin 4
- B-Cell Growth Factor-1
- B Cell Growth Factor 1
- B-Cell Growth Factor-I
- B Cell Growth Factor I
- B-Cell Proliferating Factor
- B Cell Proliferating Factor
- B-Cell Stimulating Factor-1
- B Cell Stimulating Factor 1
- B-Cell Stimulatory Factor 1
- B-Cell Stimulatory Factor-1
- BCGF-1
- Binetrakin
- BSF-1
- IL-4
- IL4
- Mast Cell Growth Factor-2
- Mast Cell Growth Factor 2
- MCGF-2
- B Cell Stimulatory Factor-1
- B Cell Stimulatory Factor 1
|
Below are MeSH descriptors whose meaning is more general than "Interleukin-4".
Below are MeSH descriptors whose meaning is more specific than "Interleukin-4".
This graph shows the total number of publications written about "Interleukin-4" by people in this website by year, and whether "Interleukin-4" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 2 | 3 |
| 1995 | 1 | 0 | 1 |
| 1996 | 1 | 1 | 2 |
| 1997 | 2 | 4 | 6 |
| 1998 | 0 | 3 | 3 |
| 1999 | 0 | 5 | 5 |
| 2001 | 2 | 0 | 2 |
| 2002 | 1 | 3 | 4 |
| 2003 | 0 | 8 | 8 |
| 2004 | 1 | 4 | 5 |
| 2005 | 2 | 0 | 2 |
| 2006 | 1 | 2 | 3 |
| 2007 | 1 | 4 | 5 |
| 2008 | 0 | 4 | 4 |
| 2009 | 2 | 1 | 3 |
| 2010 | 0 | 3 | 3 |
| 2011 | 0 | 3 | 3 |
| 2012 | 0 | 4 | 4 |
| 2013 | 0 | 1 | 1 |
| 2014 | 1 | 1 | 2 |
| 2015 | 0 | 3 | 3 |
| 2016 | 2 | 1 | 3 |
| 2017 | 3 | 3 | 6 |
| 2018 | 1 | 2 | 3 |
| 2019 | 0 | 1 | 1 |
| 2020 | 2 | 0 | 2 |
| 2021 | 2 | 1 | 3 |
| 2022 | 0 | 2 | 2 |
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click here.
Below are the most recent publications written about "Interleukin-4" by people in Profiles.
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IL-13/IL-4 signaling contributes to fibrotic progression of the myeloproliferative neoplasms. Blood. 2022 12 29; 140(26):2805-2817.
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Genome-wide association study identifies kallikrein 5 in type 2 inflammation-low asthma. J Allergy Clin Immunol. 2022 10; 150(4):972-978.e7.
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Pseudocell Tracer-A method for inferring dynamic trajectories using scRNAseq and its application to B cells undergoing immunoglobulin class switch recombination. PLoS Comput Biol. 2021 05; 17(5):e1008094.
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Wnt signaling enhances macrophage responses to IL-4 and promotes resolution of atherosclerosis. Elife. 2021 03 15; 10.
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Dysregulated microRNA expression in IL-4 transgenic mice, an animal model of atopic dermatitis. Arch Dermatol Res. 2021 Dec; 313(10):837-846.
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Prolonged residence of an albumin-IL-4 fusion protein in secondary lymphoid organs ameliorates experimental autoimmune encephalomyelitis. Nat Biomed Eng. 2021 05; 5(5):387-398.
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IL-1Rahigh-IL-4low-IL-13low: A Novel Plasma Cytokine Signature Associated with Olfactory Dysfunction in Older US Adults. Chem Senses. 2020 05 29; 45(5):407-414.
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Landscape of stimulation-responsive chromatin across diverse human immune cells. Nat Genet. 2019 10; 51(10):1494-1505.
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Transcriptional profiling identifies novel regulators of macrophage polarization. PLoS One. 2018; 13(12):e0208602.
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IL-4 dysregulates microRNAs involved in inflammation, angiogenesis and apoptosis in epidermal keratinocytes. Microbiol Immunol. 2018 Nov; 62(11):732-736.