 Actins
"Actins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Filamentous proteins that are the main constituent of the thin filaments of muscle fibers. The filaments (known also as filamentous or F-actin) can be dissociated into their globular subunits; each subunit is composed of a single polypeptide 375 amino acids long. This is known as globular or G-actin. In conjunction with MYOSINS, actin is responsible for the contraction and relaxation of muscle.
| Descriptor ID |
D000199
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| MeSH Number(s) |
D05.750.078.730.250 D12.776.210.500.100 D12.776.220.525.255
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Actins".
Below are MeSH descriptors whose meaning is more specific than "Actins".
This graph shows the total number of publications written about "Actins" by people in this website by year, and whether "Actins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1982 | 1 | 0 | 1 | | 1983 | 0 | 1 | 1 | | 1986 | 1 | 1 | 2 | | 1987 | 1 | 1 | 2 | | 1988 | 1 | 0 | 1 | | 1990 | 2 | 1 | 3 | | 1991 | 1 | 2 | 3 | | 1992 | 1 | 2 | 3 | | 1993 | 2 | 5 | 7 | | 1994 | 0 | 2 | 2 | | 1995 | 0 | 3 | 3 | | 1996 | 0 | 4 | 4 | | 1997 | 1 | 6 | 7 | | 1998 | 1 | 2 | 3 | | 1999 | 3 | 5 | 8 | | 2000 | 4 | 8 | 12 | | 2001 | 4 | 9 | 13 | | 2002 | 3 | 5 | 8 | | 2003 | 3 | 10 | 13 | | 2004 | 13 | 8 | 21 | | 2005 | 8 | 15 | 23 | | 2006 | 11 | 8 | 19 | | 2007 | 3 | 4 | 7 | | 2008 | 4 | 13 | 17 | | 2009 | 5 | 5 | 10 | | 2010 | 13 | 6 | 19 | | 2011 | 5 | 11 | 16 | | 2012 | 4 | 3 | 7 | | 2013 | 5 | 7 | 12 | | 2014 | 11 | 10 | 21 | | 2015 | 7 | 5 | 12 | | 2016 | 4 | 6 | 10 | | 2017 | 5 | 5 | 10 | | 2018 | 3 | 8 | 11 | | 2019 | 4 | 4 | 8 | | 2020 | 3 | 1 | 4 |
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Below are the most recent publications written about "Actins" by people in Profiles.
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Bryan DS, Stack M, Krysztofiak K, Cichon U, Thomas DG, Surcel A, Schiffhauer ES, Beckett MA, Khodarev NN, Xue L, Poli EC, Pearson AT, Posner MC, Robinson DN, Rock RS, Weichselbaum RR. 4-Hydroxyacetophenone modulates the actomyosin cytoskeleton to reduce metastasis. Proc Natl Acad Sci U S A. 2020 09 08; 117(36):22423-22429.
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Zhang R, Lee DM, Jimah JR, Gerassimov N, Yang C, Kim S, Luvsanjav D, Winkelman J, Mettlen M, Abrams ME, Kalia R, Keene P, Pandey P, Ravaux B, Kim JH, Ditlev JA, Zhang G, Rosen MK, Frost A, Alto NM, Gardel M, Schmid SL, Svitkina TM, Hinshaw JE, Chen EH. Dynamin regulates the dynamics and mechanical strength of the actin cytoskeleton as a multifilament actin-bundling protein. Nat Cell Biol. 2020 06; 22(6):674-688.
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Cerqueira Campos F, Dennis C, Alégot H, Fritsch C, Isabella A, Pouchin P, Bardot O, Horne-Badovinac S, Mirouse V. Oriented basement membrane fibrils provide a memory for F-actin planar polarization via the Dystrophin-Dystroglycan complex during tissue elongation. Development. 2020 04 08; 147(7).
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Santos A, Shauchuk Y, Cichon U, Vavra KC, Rock RS. How Actin Tracks Affect Myosin Motors. Adv Exp Med Biol. 2020; 1239:183-197.
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Christensen JR, Craig EW, Glista MJ, Mueller DM, Li Y, Sees JA, Huang S, Suarez C, Mets LJ, Kovar DR, Avasthi P. Chlamydomonas reinhardtii formin FOR1 and profilin PRF1 are optimized for acute rapid actin filament assembly. Mol Biol Cell. 2019 12 15; 30(26):3123-3135.
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Arzash S, McCall PM, Feng J, Gardel ML, MacKintosh FC. Stress relaxation in F-actin solutions by severing. Soft Matter. 2019 Aug 21; 15(31):6300-6307.
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Freedman SL, Suarez C, Winkelman JD, Kovar DR, Voth GA, Dinner AR, Hocky GM. Mechanical and kinetic factors drive sorting of F-actin cross-linkers on bundles. Proc Natl Acad Sci U S A. 2019 08 13; 116(33):16192-16197.
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Philip JL, Xu X, Han M, Akhter SA, Razzaque MA. Regulation of cardiac fibroblast-mediated maladaptive ventricular remodeling by ß-arrestins. PLoS One. 2019; 14(7):e0219011.
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Christensen JR, Homa KE, Morganthaler AN, Brown RR, Suarez C, Harker AJ, O'Connell ME, Kovar DR. Cooperation between tropomyosin and a-actinin inhibits fimbrin association with actin filament networks in fission yeast. Elife. 2019 06 10; 8.
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Weirich KL, Dasbiswas K, Witten TA, Vaikuntanathan S, Gardel ML. Self-organizing motors divide active liquid droplets. Proc Natl Acad Sci U S A. 2019 06 04; 116(23):11125-11130.
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