 Actins
"Actins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Filamentous proteins that are the main constituent of the thin filaments of muscle fibers. The filaments (known also as filamentous or F-actin) can be dissociated into their globular subunits; each subunit is composed of a single polypeptide 375 amino acids long. This is known as globular or G-actin. In conjunction with MYOSINS, actin is responsible for the contraction and relaxation of muscle.
| Descriptor ID |
D000199
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| MeSH Number(s) |
D05.750.078.730.250 D12.776.210.500.100 D12.776.220.525.255
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Actins".
Below are MeSH descriptors whose meaning is more specific than "Actins".
This graph shows the total number of publications written about "Actins" by people in this website by year, and whether "Actins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1982 | 1 | 0 | 1 | | 1983 | 0 | 1 | 1 | | 1986 | 1 | 1 | 2 | | 1987 | 1 | 1 | 2 | | 1988 | 1 | 0 | 1 | | 1990 | 2 | 1 | 3 | | 1991 | 1 | 2 | 3 | | 1992 | 1 | 2 | 3 | | 1993 | 2 | 4 | 6 | | 1994 | 0 | 2 | 2 | | 1995 | 1 | 3 | 4 | | 1996 | 0 | 4 | 4 | | 1997 | 1 | 6 | 7 | | 1998 | 1 | 2 | 3 | | 1999 | 3 | 5 | 8 | | 2000 | 4 | 9 | 13 | | 2001 | 4 | 9 | 13 | | 2002 | 3 | 5 | 8 | | 2003 | 3 | 10 | 13 | | 2004 | 13 | 8 | 21 | | 2005 | 9 | 15 | 24 | | 2006 | 11 | 8 | 19 | | 2007 | 3 | 5 | 8 | | 2008 | 4 | 14 | 18 | | 2009 | 5 | 5 | 10 | | 2010 | 13 | 7 | 20 | | 2011 | 5 | 11 | 16 | | 2012 | 4 | 3 | 7 | | 2013 | 5 | 7 | 12 | | 2014 | 11 | 10 | 21 | | 2015 | 7 | 6 | 13 | | 2016 | 4 | 6 | 10 | | 2017 | 5 | 5 | 10 | | 2018 | 3 | 8 | 11 | | 2019 | 4 | 4 | 8 | | 2020 | 6 | 4 | 10 | | 2021 | 6 | 2 | 8 |
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Below are the most recent publications written about "Actins" by people in Profiles.
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Bashirzadeh Y, Redford SA, Lorpaiboon C, Groaz A, Moghimianavval H, Litschel T, Schwille P, Hocky GM, Dinner AR, Liu AP. Actin crosslinker competition and sorting drive emergent GUV size-dependent actin network architecture. Commun Biol. 2021 09 28; 4(1):1136.
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Qiu Y, Nguyen M, Hocky GM, Dinner AR, Vaikuntanathan S. A strong nonequilibrium bound for sorting of cross-linkers on growing biopolymers. Proc Natl Acad Sci U S A. 2021 09 21; 118(38).
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Rosenbloom AD, Kovar EW, Kovar DR, Loew LM, Pollard TD. Mechanism of actin filament nucleation. Biophys J. 2021 10 19; 120(20):4399-4417.
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Li Y, Munro E. Filament-guided filament assembly provides structural memory of filament alignment during cytokinesis. Dev Cell. 2021 09 13; 56(17):2486-2500.e6.
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Homa KE, Zsolnay V, Anderson CA, O'Connell ME, Neidt EM, Voth GA, Bidone TC, Kovar DR. Formin Cdc12's specific actin assembly properties are tailored for cytokinesis in fission yeast. Biophys J. 2021 08 03; 120(15):2984-2997.
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Scheff DR, Redford SA, Lorpaiboon C, Majumdar S, Dinner AR, Gardel ML. Actin filament alignment causes mechanical hysteresis in cross-linked networks. Soft Matter. 2021 Jun 09; 17(22):5499-5507.
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Yde SE, Kadzik RS, Kovar DR. Stir it up: The role of actin in mitochondrial mixing during mitosis. Dev Cell. 2021 04 19; 56(8):1080-1082.
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Weirich KL, Stam S, Munro E, Gardel ML. Actin bundle architecture and mechanics regulate myosin II force generation. Biophys J. 2021 05 18; 120(10):1957-1970.
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Fujimori D, Kinoshita J, Yamaguchi T, Nakamura Y, Gunjigake K, Ohama T, Sato K, Yamamoto M, Tsukamoto T, Nomura S, Ohta T, Fushida S. Established fibrous peritoneal metastasis in an immunocompetent mouse model similar to clinical immune microenvironment of gastric cancer. BMC Cancer. 2020 Oct 20; 20(1):1014.
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Kadzik RS, Homa KE, Kovar DR. F-Actin Cytoskeleton Network Self-Organization Through Competition and Cooperation. Annu Rev Cell Dev Biol. 2020 10 06; 36:35-60.
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