 Affinity Labels
"Affinity Labels" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Analogs of those substrates or compounds which bind naturally at the active sites of proteins, enzymes, antibodies, steroids, or physiological receptors. These analogs form a stable covalent bond at the binding site, thereby acting as inhibitors of the proteins or steroids.
| Descriptor ID |
D000345
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| MeSH Number(s) |
D27.720.470.410.080
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| Concept/Terms |
Affinity Labels- Affinity Labels
- Labels, Affinity
- Affinity Labeling Reagents
- Labeling Reagents, Affinity
- Reagents, Affinity Labeling
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Below are MeSH descriptors whose meaning is more general than "Affinity Labels".
Below are MeSH descriptors whose meaning is more specific than "Affinity Labels".
This graph shows the total number of publications written about "Affinity Labels" by people in this website by year, and whether "Affinity Labels" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1985 | 0 | 1 | 1 | | 1988 | 0 | 2 | 2 | | 1989 | 0 | 1 | 1 | | 1992 | 0 | 4 | 4 | | 1998 | 0 | 1 | 1 | | 2009 | 0 | 1 | 1 |
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Below are the most recent publications written about "Affinity Labels" by people in Profiles.
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Huang J, Nagy SS, Koide A, Rock RS, Koide S. A peptide tag system for facile purification and single-molecule immobilization. Biochemistry. 2009 Dec 22; 48(50):11834-6.
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Ernsberger P, Kou YR, Prabhakar NR. Carotid body I1-imidazoline receptors: binding, visualization and modulatory function. Respir Physiol. 1998 Jun; 112(3):239-51.
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Platanias LC, Pfeffer LM, Barton KP, Vardiman JW, Golomb HM, Colamonici OR. Expression of the IFN alpha receptor in hairy cell leukaemia. Br J Haematol. 1992 Nov; 82(3):541-6.
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Glucksmann MA, Markiewicz P, Malone C, Rothman-Denes LB. Specific sequences and a hairpin structure in the template strand are required for N4 virion RNA polymerase promoter recognition. Cell. 1992 Aug 07; 70(3):491-500.
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Hartman J, Huang Z, Rado TA, Peng S, Jilling T, Muccio DD, Sorscher EJ. Recombinant synthesis, purification, and nucleotide binding characteristics of the first nucleotide binding domain of the cystic fibrosis gene product. J Biol Chem. 1992 Apr 05; 267(10):6455-8.
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Fleming GF, Amato JM, Agresti M, Safa AR. Megestrol acetate reverses multidrug resistance and interacts with P-glycoprotein. Cancer Chemother Pharmacol. 1992; 29(6):445-9.
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Podkowinski J, Gornicki P. Neighbourhood of the central fold of the tRNA molecule bound to the E. coli ribosome--affinity labeling studies with modified tRNAs carrying photoreactive probes attached to the dihydrouridine loop. Nucleic Acids Res. 1991 Feb 25; 19(4):801-8.
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Safa AR, Agresti M, Tamai I, Mehta ND, Vahabi S. The alpha 1-adrenergic photoaffinity probe [125I]arylazidoprazosin binds to a specific peptide of P-glycoprotein in multidrug-resistant cells. Biochem Biophys Res Commun. 1990 Jan 15; 166(1):259-66.
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Harlow KW, Smith DN, Katzenellenbogen JA, Greene GL, Katzenellenbogen BS. Identification of cysteine 530 as the covalent attachment site of an affinity-labeling estrogen (ketononestrol aziridine) and antiestrogen (tamoxifen aziridine) in the human estrogen receptor. J Biol Chem. 1989 Oct 15; 264(29):17476-85.
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Safa AR, Mehta ND, Agresti M. Photoaffinity labeling of P-glycoprotein in multidrug resistant cells with photoactive analogs of colchicine. Biochem Biophys Res Commun. 1989 Aug 15; 162(3):1402-8.
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