"Reactive Oxygen Species" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Molecules or ions formed by the incomplete one-electron reduction of oxygen. These reactive oxygen intermediates include SINGLET OXYGEN; SUPEROXIDES; PEROXIDES; HYDROXYL RADICAL; and HYPOCHLOROUS ACID. They contribute to the microbicidal activity of PHAGOCYTES, regulation of SIGNAL TRANSDUCTION and GENE EXPRESSION, and the oxidative damage to NUCLEIC ACIDS; PROTEINS; and LIPIDS.
| Descriptor ID |
D017382
|
| MeSH Number(s) |
D01.339.431 D01.650.775
|
| Concept/Terms |
Reactive Oxygen Species- Reactive Oxygen Species
- Oxygen Species, Reactive
- Active Oxygen
- Oxygen, Active
- Oxygen Radicals
- Pro-Oxidants
- Pro Oxidants
|
Below are MeSH descriptors whose meaning is more general than "Reactive Oxygen Species".
Below are MeSH descriptors whose meaning is more specific than "Reactive Oxygen Species".
This graph shows the total number of publications written about "Reactive Oxygen Species" by people in this website by year, and whether "Reactive Oxygen Species" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1997 | 1 | 0 | 1 |
| 1998 | 1 | 0 | 1 |
| 1999 | 4 | 2 | 6 |
| 2000 | 3 | 1 | 4 |
| 2001 | 1 | 6 | 7 |
| 2002 | 4 | 9 | 13 |
| 2003 | 2 | 6 | 8 |
| 2004 | 5 | 5 | 10 |
| 2005 | 4 | 1 | 5 |
| 2006 | 8 | 11 | 19 |
| 2007 | 8 | 7 | 15 |
| 2008 | 4 | 10 | 14 |
| 2009 | 6 | 12 | 18 |
| 2010 | 8 | 18 | 26 |
| 2011 | 11 | 21 | 32 |
| 2012 | 6 | 13 | 19 |
| 2013 | 3 | 16 | 19 |
| 2014 | 4 | 14 | 18 |
| 2015 | 3 | 10 | 13 |
| 2016 | 2 | 16 | 18 |
| 2017 | 5 | 11 | 16 |
| 2018 | 5 | 12 | 17 |
| 2019 | 3 | 6 | 9 |
| 2020 | 1 | 10 | 11 |
| 2021 | 4 | 8 | 12 |
| 2022 | 0 | 5 | 5 |
| 2023 | 0 | 8 | 8 |
| 2024 | 1 | 6 | 7 |
| 2025 | 2 | 3 | 5 |
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Below are the most recent publications written about "Reactive Oxygen Species" by people in Profiles.
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The integrated stress response promotes macrophage inflammation and migration in autoimmune diabetes. Cell Commun Signal. 2025 Aug 20; 23(1):374.
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Nanoscale Donor-Acceptor Covalent Organic Frameworks for Mitochondria-Targeted Sonodynamic Therapy and Antitumor Immunity. J Am Chem Soc. 2025 Jul 23; 147(29):25622-25634.
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Transforming malignant tumors into vulnerable phenotypes via nanoscale coordination polymer mediated cell senescence and photodynamic therapy. Biomaterials. 2025 Nov; 322:123355.
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Reactive Oxygen Species (ROS) in Metabolic Disease-Don't Shoot the Metabolic Messenger. Int J Mol Sci. 2025 Mar 14; 26(6).
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Dynamic PRDX S-acylation modulates ROS stress and signaling. Cell Chem Biol. 2025 Mar 20; 32(3):511-519.e5.
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Digitonin-Loaded Nanoscale Metal-Organic Framework for Mitochondria-Targeted Radiotherapy-Radiodynamic Therapy and Disulfidptosis. Adv Mater. 2025 Dec; 37(52):e2405494.
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A Glutathione-Consuming Bimetallic Nano-Bomb with the Combination of Photothermal and Chemodynamic Therapy for Tumors: An in vivo and in vitro Study. Int J Nanomedicine. 2024; 19:8541-8553.
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Loss of Fic causes progressive neurodegeneration in a Drosophila model of hereditary spastic paraplegia. Biochim Biophys Acta Mol Basis Dis. 2024 10; 1870(7):167348.
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Neuroprotective and Anti-Inflammatory Activities of Hybrid Small-Molecule SA-10 in Ischemia/Reperfusion-Induced Retinal Neuronal Injury Models. Cells. 2024 02 25; 13(5).
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Amifostine ameliorates bleomycin-induced murine pulmonary fibrosis via NAD+/SIRT1/AMPK pathway-mediated effects on mitochondrial function and cellular metabolism. Eur J Med Res. 2024 Jan 20; 29(1):68.