 Autophagy
"Autophagy" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The segregation and degradation of damaged or unwanted cytoplasmic constituents by autophagic vacuoles (cytolysosomes) composed of LYSOSOMES containing cellular components in the process of digestion; it plays an important role in BIOLOGICAL METAMORPHOSIS of amphibians, in the removal of bone by osteoclasts, and in the degradation of normal cell components in nutritional deficiency states.
| Descriptor ID |
D001343
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| MeSH Number(s) |
G04.299.139.399 G04.299.482.350.091
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| Concept/Terms |
Autophagy- Autophagy
- Autophagies
- Autophagocytosis
- Autophagy, Cellular
- Autophagies, Cellular
- Cellular Autophagies
- Cellular Autophagy
Programmed Cell Death, Type II- Programmed Cell Death, Type II
- Autophagic Programmed Cell Death
- Autophagic Cell Death
- Autophagic Cell Deaths
- Cell Death, Autophagic
- Cell Deaths, Autophagic
- Death, Autophagic Cell
- Deaths, Autophagic Cell
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Below are MeSH descriptors whose meaning is more general than "Autophagy".
Below are MeSH descriptors whose meaning is more specific than "Autophagy".
This graph shows the total number of publications written about "Autophagy" by people in this website by year, and whether "Autophagy" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1991 | 1 | 0 | 1 | | 2004 | 1 | 0 | 1 | | 2005 | 1 | 0 | 1 | | 2007 | 7 | 0 | 7 | | 2008 | 1 | 0 | 1 | | 2009 | 1 | 2 | 3 | | 2010 | 6 | 1 | 7 | | 2011 | 3 | 0 | 3 | | 2012 | 6 | 1 | 7 | | 2013 | 4 | 1 | 5 | | 2014 | 3 | 8 | 11 | | 2015 | 7 | 4 | 11 | | 2016 | 7 | 1 | 8 | | 2017 | 5 | 7 | 12 | | 2018 | 6 | 2 | 8 | | 2019 | 6 | 2 | 8 | | 2020 | 2 | 0 | 2 |
To return to the timeline, click here.
Below are the most recent publications written about "Autophagy" by people in Profiles.
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Patel NH, Xu J, Saleh T, Wu Y, Lima S, Gewirtz DA. Influence of nonprotective autophagy and the autophagic switch on sensitivity to cisplatin in non-small cell lung cancer cells. Biochem Pharmacol. 2020 05; 175:113896.
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Saleh T, Tyutyunyk-Massey L, Patel NH, Cudjoe EK, Alotaibi M, Gewirtz DA. Studies of Non-Protective Autophagy Provide Evidence that Recovery from Therapy-Induced Senescence is Independent of Early Autophagy. Int J Mol Sci. 2020 02 20; 21(4).
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Serman TM, Gack MU. Evasion of Innate and Intrinsic Antiviral Pathways by the Zika Virus. Viruses. 2019 10 22; 11(10).
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Sheng T, Sun Y, Sun J, Prinz RA, Peng D, Liu X, Xu X. Role of TGF-ß-activated kinase 1 (TAK1) activation in H5N1 influenza A virus-induced c-Jun terminal kinase activation and virus replication. Virology. 2019 11; 537:263-271.
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Liu W, Zhuang J, Jiang Y, Sun J, Prinz RA, Sun J, Jiao X, Xu X. Toll-like receptor signalling cross-activates the autophagic pathway to restrict Salmonella Typhimurium growth in macrophages. Cell Microbiol. 2019 12; 21(12):e13095.
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Liu X, Matrenec R, Gack MU, He B. Disassembly of the TRIM23-TBK1 Complex by the Us11 Protein of Herpes Simplex Virus 1 Impairs Autophagy. J Virol. 2019 09 01; 93(17).
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Zhou J, Waskowicz LR, Lim A, Liao XH, Lian B, Masamune H, Refetoff S, Tran B, Koeberl DD, Yen PM. A Liver-Specific Thyromimetic, VK2809, Decreases Hepatosteatosis in Glycogen Storage Disease Type Ia. Thyroid. 2019 08; 29(8):1158-1167.
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Anderson CM, Macleod KF. Autophagy and cancer cell metabolism. Int Rev Cell Mol Biol. 2019; 347:145-190.
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Zhang YG, Zhu X, Lu R, Messer JS, Xia Y, Chang EB, Sun J. Intestinal epithelial HMGB1 inhibits bacterial infection via STAT3 regulation of autophagy. Autophagy. 2019 11; 15(11):1935-1953.
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Jin HR, Du CH, Wang CZ, Yuan CS, Du W. Ginseng metabolite Protopanaxadiol induces Sestrin2 expression and AMPK activation through GCN2 and PERK. Cell Death Dis. 2019 04 05; 10(4):311.
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