"Autophagy" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The segregation and degradation of cytoplasmic constituents by AUTOPHAGOSOMES and their digestion by LYSOSOMES. It plays an important role in BIOLOGICAL METAMORPHOSIS and in the removal of bone by OSTEOCLASTS. Defective autophagy is associated with various diseases, including NEURODEGENERATIVE DISEASES and cancer.
| Descriptor ID |
D001343
|
| MeSH Number(s) |
G04.146.399 G04.417.350.091
|
| Concept/Terms |
Autophagy- Autophagy
- Autophagies
- Macro-autophagy
- Macro autophagy
- Macro-autophagies
- Autophagy, Cellular
- Autophagies, Cellular
- Cellular Autophagies
- Cellular Autophagy
- Macroautophagy
- Macroautophagies
- Autophagocytosis
Programmed Cell Death, Type II- Programmed Cell Death, Type II
- Autophagic Cell Death
- Autophagic Cell Deaths
- Cell Death, Autophagic
- Cell Deaths, Autophagic
- Death, Autophagic Cell
- Deaths, Autophagic Cell
- Autophagic Programmed Cell Death
|
Below are MeSH descriptors whose meaning is more general than "Autophagy".
Below are MeSH descriptors whose meaning is more specific than "Autophagy".
This graph shows the total number of publications written about "Autophagy" by people in this website by year, and whether "Autophagy" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 1 | 0 | 1 |
| 2005 | 1 | 0 | 1 |
| 2007 | 7 | 0 | 7 |
| 2008 | 1 | 0 | 1 |
| 2009 | 1 | 2 | 3 |
| 2010 | 6 | 1 | 7 |
| 2011 | 3 | 1 | 4 |
| 2012 | 6 | 1 | 7 |
| 2013 | 5 | 1 | 6 |
| 2014 | 3 | 7 | 10 |
| 2015 | 7 | 4 | 11 |
| 2016 | 6 | 1 | 7 |
| 2017 | 5 | 7 | 12 |
| 2018 | 4 | 2 | 6 |
| 2019 | 5 | 1 | 6 |
| 2020 | 7 | 1 | 8 |
| 2021 | 6 | 5 | 11 |
| 2022 | 0 | 3 | 3 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Autophagy" by people in Profiles.
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Perturbation of endoplasmic reticulum proteostasis triggers tissue injury in the thyroid gland. JCI Insight. 2023 06 22; 8(12).
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Inside the ß Cell: Molecular Stress Response Pathways in Diabetes Pathogenesis. Endocrinology. 2022 Nov 14; 164(1).
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Docosahexaenoic Acid Suppresses Oxidative Stress-Induced Autophagy and Cell Death via the AMPK-Dependent Signaling Pathway in Immortalized Fischer Rat Schwann Cells 1. Int J Mol Sci. 2022 Apr 15; 23(8).
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In search of autophagy biomarkers in breast cancer: Receptor status and drug agnostic transcriptional changes during autophagy flux in cell lines. PLoS One. 2022; 17(1):e0262134.
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Early DNA damage detection and cellular autophagy as drivers of stress-adaptive H2S production: A paradox resolved. Cell Chem Biol. 2021 12 16; 28(12):1665-1668.
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Tubular lysosomes harbor active ion gradients and poise macrophages for phagocytosis. Proc Natl Acad Sci U S A. 2021 10 12; 118(41).
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Autophagy-mitophagy induction attenuates cardiovascular inflammation in a murine model of Kawasaki disease vasculitis. JCI Insight. 2021 09 22; 6(18).
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METTL14 facilitates global genome repair and suppresses skin tumorigenesis. Proc Natl Acad Sci U S A. 2021 08 31; 118(35).
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Autophagy in major human diseases. EMBO J. 2021 10 01; 40(19):e108863.
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Inhibition of the sonic hedgehog pathway activates TGF-ß-activated kinase (TAK1) to induce autophagy and suppress apoptosis in thyroid tumor cells. Cell Death Dis. 2021 05 08; 12(5):459.