"Acetylcholinesterase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the hydrolysis of ACETYLCHOLINE to CHOLINE and acetate. In the CNS, this enzyme plays a role in the function of peripheral neuromuscular junctions. EC 3.1.1.7.
| Descriptor ID |
D000110
|
| MeSH Number(s) |
D08.811.277.352.100.170.176
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Acetylcholinesterase".
Below are MeSH descriptors whose meaning is more specific than "Acetylcholinesterase".
This graph shows the total number of publications written about "Acetylcholinesterase" by people in this website by year, and whether "Acetylcholinesterase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 2 | 1 | 3 |
| 1995 | 1 | 0 | 1 |
| 1996 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 4 | 4 |
| 2003 | 0 | 2 | 2 |
| 2004 | 1 | 1 | 2 |
| 2008 | 0 | 2 | 2 |
| 2009 | 0 | 1 | 1 |
| 2011 | 0 | 2 | 2 |
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Acetylcholinesterase" by people in Profiles.
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Variations in Acetylcholinesterase Activity within Human Cortical Pyramidal Neurons Across Age and Cognitive Trajectories. Cereb Cortex. 2018 04 01; 28(4):1329-1337.
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Identification and Expression of Acetylcholinesterase in Octopus vulgaris Arm Development and Regeneration: a Conserved Role for ACHE? Mol Neurobiol. 2015 Aug; 52(1):45-56.
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Chemical analog-to-digital signal conversion based on robust threshold chemistry and its evaluation in the context of microfluidics-based quantitative assays. J Am Chem Soc. 2013 Oct 02; 135(39):14775-83.
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Synaptic basal lamina-associated congenital myasthenic syndromes. Ann N Y Acad Sci. 2012 Dec; 1275:36-48.
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LG2 agrin mutation causing severe congenital myasthenic syndrome mimics functional characteristics of non-neural (z-) agrin. Hum Genet. 2012 Jul; 131(7):1123-35.
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Coordinated regulation of cholinergic motor neuron traits through a conserved terminal selector gene. Nat Neurosci. 2011 Nov 27; 15(2):205-14.
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Predicting protein function and binding profile via matching of local evolutionary and geometric surface patterns. J Mol Biol. 2009 Mar 27; 387(2):451-64.
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Behavioral evaluation of rats following low-level inhalation exposure to sarin. Pharmacol Biochem Behav. 2009 Feb; 91(4):517-25.
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Essential roles of the acetylcholine receptor gamma-subunit in neuromuscular synaptic patterning. Development. 2008 Jun; 135(11):1957-67.
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Imidacloprid induces neurobehavioral deficits and increases expression of glial fibrillary acidic protein in the motor cortex and hippocampus in offspring rats following in utero exposure. J Toxicol Environ Health A. 2008; 71(2):119-30.