 Actinin
"Actinin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A protein factor that regulates the length of R-actin. It is chemically similar, but immunochemically distinguishable from actin.
| Descriptor ID |
D000185
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| MeSH Number(s) |
D05.750.078.730.248 D12.776.210.500.095 D12.776.220.525.250
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Actinin".
Below are MeSH descriptors whose meaning is more specific than "Actinin".
This graph shows the total number of publications written about "Actinin" by people in this website by year, and whether "Actinin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 1 | 0 | 1 | | 2008 | 1 | 1 | 2 | | 2010 | 2 | 0 | 2 | | 2011 | 1 | 0 | 1 | | 2012 | 1 | 1 | 2 | | 2014 | 1 | 1 | 2 | | 2016 | 2 | 1 | 3 | | 2017 | 0 | 1 | 1 | | 2019 | 1 | 2 | 3 |
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Below are the most recent publications written about "Actinin" by people in Profiles.
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Freedman SL, Suarez C, Winkelman JD, Kovar DR, Voth GA, Dinner AR, Hocky GM. Mechanical and kinetic factors drive sorting of F-actin cross-linkers on bundles. Proc Natl Acad Sci U S A. 2019 08 13; 116(33):16192-16197.
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Christensen JR, Homa KE, Morganthaler AN, Brown RR, Suarez C, Harker AJ, O'Connell ME, Kovar DR. Cooperation between tropomyosin and a-actinin inhibits fimbrin association with actin filament networks in fission yeast. Elife. 2019 06 10; 8.
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Harker AJ, Katkar HH, Bidone TC, Aydin F, Voth GA, Applewhite DA, Kovar DR. Ena/VASP processive elongation is modulated by avidity on actin filaments bundled by the filopodia cross-linker fascin. Mol Biol Cell. 2019 03 21; 30(7):851-862.
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Hissa B, Oakes PW, Pontes B, RamÃrez-San Juan G, Gardel ML. Cholesterol depletion impairs contractile machinery in neonatal rat cardiomyocytes. Sci Rep. 2017 03 03; 7:43764.
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Sugiura T, Hibino N, Breuer CK, Shinoka T. Tissue-engineered cardiac patch seeded with human induced pluripotent stem cell derived cardiomyocytes promoted the regeneration of host cardiomyocytes in a rat model. J Cardiothorac Surg. 2016 Dec 01; 11(1):163.
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Winkelman JD, Suarez C, Hocky GM, Harker AJ, Morganthaler AN, Christensen JR, Voth GA, Bartles JR, Kovar DR. Fascin- and a-Actinin-Bundled Networks Contain Intrinsic Structural Features that Drive Protein Sorting. Curr Biol. 2016 10 24; 26(20):2697-2706.
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Li Y, Christensen JR, Homa KE, Hocky GM, Fok A, Sees JA, Voth GA, Kovar DR. The F-actin bundler a-actinin Ain1 is tailored for ring assembly and constriction during cytokinesis in fission yeast. Mol Biol Cell. 2016 06 01; 27(11):1821-33.
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Sharma S, Mayank AK, Nailwal H, Tripathi S, Patel JR, Bowzard JB, Gaur P, Donis RO, Katz JM, Cox NJ, Lal RB, Farooqi H, Sambhara S, Lal SK. Influenza A viral nucleoprotein interacts with cytoskeleton scaffolding protein a-actinin-4 for viral replication. FEBS J. 2014 Jul; 281(13):2899-914.
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Burnette DT, Shao L, Ott C, Pasapera AM, Fischer RS, Baird MA, Der Loughian C, Delanoe-Ayari H, Paszek MJ, Davidson MW, Betzig E, Lippincott-Schwartz J. A contractile and counterbalancing adhesion system controls the 3D shape of crawling cells. J Cell Biol. 2014 Apr 14; 205(1):83-96.
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Falzone TT, Lenz M, Kovar DR, Gardel ML. Assembly kinetics determine the architecture of a-actinin crosslinked F-actin networks. Nat Commun. 2012 May 29; 3:861.
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