"DNA Polymerase II" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A DNA-dependent DNA polymerase characterized in E. coli and other lower organisms. It may be present in higher organisms and has an intrinsic molecular activity only 5% of that of DNA Polymerase I. This polymerase has 3'-5' exonuclease activity, is effective only on duplex DNA with gaps or single-strand ends of less than 100 nucleotides as template, and is inhibited by sulfhydryl reagents. EC 2.7.7.7.
| Descriptor ID |
D004257
|
| MeSH Number(s) |
D08.811.913.696.445.308.300.230
|
| Concept/Terms |
DNA Polymerase II- DNA Polymerase II
- DNA Polymerase epsilon
- DNA-Dependent DNA Polymerase II
- DNA Dependent DNA Polymerase II
- DNA Pol II
|
Below are MeSH descriptors whose meaning is more general than "DNA Polymerase II".
Below are MeSH descriptors whose meaning is more specific than "DNA Polymerase II".
This graph shows the total number of publications written about "DNA Polymerase II" by people in this website by year, and whether "DNA Polymerase II" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 |
| 1997 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
| 2024 | 1 | 1 | 2 |
To return to the timeline,
click here.
Below are the most recent publications written about "DNA Polymerase II" by people in Profiles.
-
Comprehensive molecular characterization of early stage grade 3 endometrioid endometrial adenocarcinoma. Gynecol Oncol. 2024 Oct; 189:138-145.
-
Immune checkpoint inhibitors for POLE or POLD1 proofreading-deficient metastatic colorectal cancer. Ann Oncol. 2024 Jul; 35(7):643-655.
-
Clinical activity and safety of atezolizumab in patients with recurrent glioblastoma. J Neurooncol. 2018 Nov; 140(2):317-328.
-
HP1BP3, a Chromatin Retention Factor for Co-transcriptional MicroRNA Processing. Mol Cell. 2016 08 04; 63(3):420-32.
-
Association of Polymerase e-Mutated and Microsatellite-Instable Endometrial Cancers With Neoantigen Load, Number of Tumor-Infiltrating Lymphocytes, and Expression of PD-1 and PD-L1. JAMA Oncol. 2015 Dec; 1(9):1319-23.
-
Integrated genomic characterization of endometrial carcinoma. Nature. 2013 May 02; 497(7447):67-73.
-
Coupled transcription-splicing regulation of mutually exclusive splicing events at the 5' exons of protein 4.1R gene. Blood. 2009 Nov 05; 114(19):4233-42.
-
Highly transcribed RNA polymerase II genes are impediments to replication fork progression in Saccharomyces cerevisiae. Mol Cell. 2009 Jun 26; 34(6):722-34.
-
KGF facilitates repair of radiation-induced DNA damage in alveolar epithelial cells. Am J Physiol. 1997 Jun; 272(6 Pt 1):L1174-80.
-
Elevated DNA polymerase alpha, DNA polymerase beta, and DNA topoisomerase II in a melphalan-resistant rhabdomyosarcoma xenograft that is cross-resistant to nitrosoureas and topotecan. Cancer Res. 1994 Jul 01; 54(13):3487-93.