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Jeffrey Hubbell

TitleBarry L. MacLean Professor
InstitutionUniversity of Chicago
DepartmentPritzker Institute for Molecular Engineering
AddressChicago IL 60637
Email
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    Collapse Research 
    Collapse research activities and funding
    R21CA277414     (HUBBELL, JEFFREY A.)Aug 1, 2023 - Jul 31, 2025
    NIH
    Inducing Tumor Neoantigens Through RNA Editing for Cancer Immunotherapy
    Role: Principal Investigator
    DP3DK108215     (HUBBELL, JEFFREY A.)Sep 25, 2015 - Jul 31, 2019
    NIH
    Engineering Growth Factor-ECM Interactions to Heal Chronic Wounds in Type 1 Diabetes
    Role: Principal Investigator
    R01HL056297     (HUBBELL, JEFFREY A)May 1, 1996 - Apr 30, 2000
    NIH
    INTRAVASCULAR GELS FOR MODULATION OF ARTERIAL HEALING
    Role: Principal Investigator
    T32GM008346     (DERVAN, PETER B.)Sep 27, 1989 - Sep 30, 1999
    NIH
    PREDOCTORAL TRAINING IN BIOTECHNOLOGY
    Role: Co-Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. White MJV, Raczy MM, Budina E, Yuba E, Solanki A, Shim HN, Zhang ZJ, Gray LT, Cao S, Alpar AT, Hubbell JA. Engineering IL-10 and rapamycin to bind collagen leads to improved anti fibrotic efficacy in lung and kidney fibrosis. Sci Rep. 2025 Apr 17; 15(1):13279. PMID: 40246931; PMCID: PMC12006466.
      Citations:    Fields:    Translation:HumansAnimals
    2. Li N, Kang S, Liu Z, Wai S, Cheng Z, Dai Y, Solanki A, Li S, Li Y, Strzalka J, White MJV, Kim YH, Tian B, Hubbell JA, Wang S. Immune-compatible designs of semiconducting polymers for bioelectronics with suppressed foreign-body response. Nat Mater. 2025 Apr 17. PMID: 40247019.
      Citations:    Fields:    
    3. Gómez Medellín JE, Ung TWM, Wang T, Chang K, Cassano A, Kurtanich T, Reda JW, Shema KE, Stanic N, Slezak AJ, Vuong I, Chen B, Cao S, Alegre ML, Swartz MA, Hubbell JA. Liver-targeted allergen immunotherapy rapidly and safely induces antigen-specific tolerance to treat allergic airway disease in mice. Sci Transl Med. 2025 Apr 16; 17(794):eadl0406. PMID: 40238914.
      Citations: 1     Fields:    Translation:AnimalsCells
    4. Kang S, Mansurov A, Kurtanich T, Chun HR, Slezak AJ, Volpatti LR, Chang K, Wang T, Alpar AT, Refvik KC, Hansen OI, Borjas GJ, Berg BTK, Shim HN, Hultgren KT, Gomes S, Wang Y, Solanki A, Ishihara J, Swartz MA, Hubbell JA. Engineered GM-CSF polarizes protumorigenic tumor-associated macrophages to an antitumorigenic phenotype and potently synergizes with IL-12 immunotherapy. J Immunother Cancer. 2024 Dec 22; 12(12). PMID: 39794939; PMCID: PMC11667343.
      Citations:    Fields:    Translation:HumansAnimalsCells
    5. Vythlingam G, Larsson HM, Yeoh WS, Zainuddin SAM, Engelhardt EM, Sanmugam A, Ch'ng YL, Foong YX, Harto MKAW, Pinnagoda K, Chen HC, Radzi R, Hiew M, Khairuddin NH, Rajandram R, Sothilingam S, Rajendrarao TC, Hubbell JA, Frey P, Joshi PM, Kulkarni SB, Ong TA, Vythilingam G, Larsson HM, Yeoh WS, Zainuddin SAM, Engelhardt EM, Sanmugam A, Ch'ng YL, Foong YX, Harto MKAW, Pinnagoda K, Chen HC, Radzi R, Hiew M, Khairuddin NH, Rajandram R, Sothilingam S, Rajendrarao TC, Kamarul Zaman Tunku Zainol Abidin T, Hubbell JA, Frey P, Joshi PM, Kulkarni SB, Ong TA. Off-the-Shelf Implant to Bridge a Urethral Defect: Multicenter 8-Year Journey From Bench to Bed. Urology. 2025 Feb; 196:294-299. PMID: 39710073.
      Citations:    Fields:    Translation:HumansAnimals
    6. Sepulveda M, Kwan M, Chen L, Cassano A, Cao S, Wang R, Slezak AJ, Hubbell JA, Nagler CR, Alegre ML, Cao S. Delivery of butyrate to the lower gut by polymeric micelles prolongs survival of distal skin allografts. Am J Transplant. 2025 Apr; 25(4):695-705. PMID: 39566659; PMCID: PMC11972890.
      Citations:    Fields:    Translation:Animals
    7. White MJV, Ozkan M, Gomez-Medellin JE, Raczy MM, Koss KM, Solanki A, Zhang ZJ, Alpar AT, Naved BA, Wertheim J, Hubbell JA. Blocking antibodies against integrin-a3, -aM, and -aMß2 de-differentiate myofibroblasts, and improve lung fibrosis and kidney fibrosis. Sci Rep. 2024 09 16; 14(1):21623. PMID: 39284829; PMCID: PMC11405753.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    8. Schwager JM, Di Maggio N, Grosso A, Rasadurai A, Minder N, Hubbell JA, Kappos EA, Schaefer DJ, Briquez PS, Banfi A, Burger MG. Semaphorin 3A promotes the long-term persistence of human SVF-derived microvascular networks in engineered grafts. Front Bioeng Biotechnol. 2024; 12:1396450. PMID: 39234267; PMCID: PMC11371724.
      Citations: 1     
    9. Cao S, Budina E, Wang R, Sabados M, Mukherjee A, Solanki A, Nguyen M, Hultgren K, Dhar A, Hubbell JA. Injectable butyrate-prodrug micelles induce long-acting immune modulation and prevent autoimmune arthritis in mice. J Control Release. 2024 Aug; 372:281-294. PMID: 38876359.
      Citations: 1     Fields:    Translation:Animals
    10. Slezak AJ, Chang K, Beckman TN, Refvik KC, Alpar AT, Lauterbach AL, Solanki A, Kwon JW, Gomes S, Mansurov A, Hubbell JA. Cysteine-binding adjuvant enhances survival and promotes immune function in a murine model of acute myeloid leukemia. Blood Adv. 2024 04 09; 8(7):1747-1759. PMID: 38324726; PMCID: PMC10985806.
      Citations: 1     Fields:    Translation:HumansAnimals
    11. Cao S, Budina E, Raczy MM, Solanki A, Nguyen M, Beckman TN, Reda JW, Hultgren K, Ang PS, Slezak AJ, Hesser LA, Alpar AT, Refvik KC, Shores LS, Pillai I, Wallace RP, Dhar A, Watkins EA, Hubbell JA. A serine-conjugated butyrate prodrug with high oral bioavailability suppresses autoimmune arthritis and neuroinflammation in mice. Nat Biomed Eng. 2024 May; 8(5):611-627. PMID: 38561491; PMCID: PMC11161413.
      Citations: 5     Fields:    Translation:Animals
    12. Volpatti LR, de Matos SN, Borjas G, Reda J, Watkins EA, Zhou Z, Nguyen M, Solanki A, Fang Y, Hubbell JA. LDL-Binding IL-10 Reduces Vascular Inflammation in Atherosclerotic Mice. bioRxiv. 2024 Mar 06. PMID: 38496521; PMCID: PMC10942346.
      Citations:    
    13. Slezak A, Chang K, Hossainy S, Mansurov A, Rowan SJ, Hubbell JA, Guler MO. Therapeutic synthetic and natural materials for immunoengineering. Chem Soc Rev. 2024 Feb 19; 53(4):1789-1822. PMID: 38170619; PMCID: PMC11557218.
      Citations: 5     Fields:    
    14. Hubbell JA. Immunoengineering a Future of Molecular, Material, and Cellular Therapeutics. J Immunol. 2024 01 15; 212(2):167-168. PMID: 38166250.
      Citations:    Fields:    
    15. Cao S, Maulloo CD, Raczy MM, Sabados M, Slezak AJ, Nguyen M, Solanki A, Wallace RP, Shim HN, Wilson DS, Hubbell JA. Glycosylation-modified antigens as a tolerance-inducing vaccine platform prevent anaphylaxis in a pre-clinical model of food allergy. Cell Rep Med. 2024 01 16; 5(1):101346. PMID: 38128531; PMCID: PMC10829738.
      Citations: 3     Fields:    Translation:AnimalsCells
    16. Wallace RP, Refvik KC, Antane JT, Brünggel K, Tremain AC, Raczy MR, Alpar AT, Nguyen M, Solanki A, Slezak AJ, Watkins EA, Lauterbach AL, Cao S, Wilson DS, Hubbell JA. Synthetically mannosylated antigens induce antigen-specific humoral tolerance and reduce anti-drug antibody responses to immunogenic biologics. Cell Rep Med. 2024 01 16; 5(1):101345. PMID: 38128533; PMCID: PMC10829756.
      Citations: 3     Fields:    Translation:HumansCells
    17. Kang S, Mansurov A, Kurtanich T, Chun HR, Slezak AJ, Volpatti LR, Chang K, Wang T, Alpar AT, Refvik KC, Hansen OI, Borjas GJ, Shim HN, Hultgren KT, Gomes S, Solanki A, Ishihara J, Swartz MA, Hubbell JA. Engineered IL-7 synergizes with IL-12 immunotherapy to prevent T cell exhaustion and promote memory without exacerbating toxicity. Sci Adv. 2023 12; 9(48):eadh9879. PMID: 38019919; PMCID: PMC10686557.
      Citations: 8     Fields:    Translation:Humans
    18. Lauterbach AL, Wallace RP, Alpar AT, Refvik KC, Reda JW, Ishihara A, Beckman TN, Slezak AJ, Mizukami Y, Mansurov A, Gomes S, Ishihara J, Hubbell JA. Author Correction: Topically-applied collagen-binding serum albumin-fused interleukin-4 modulates wound microenvironment in non-healing wounds. NPJ Regen Med. 2023 Nov 02; 8(1):62. PMID: 37919358; PMCID: PMC10622512.
      Citations:    
    19. Wallace RP, Refvik KC, Antane JT, Tremain AC, Raczy MR, Alpar AT, Nguyen M, Solanki A, Slezak AJ, Watkins EA, Lauterbach AL, Cao S, Wilson DS, Hubbell JA, Brünggel K. Synthetically mannosylated antigens induce antigen-specific humoral tolerance and reduce anti-drug antibody responses to immunogenic biologics. bioRxiv. 2023 Sep 19. PMID: 37066302; PMCID: PMC10104138.
      Citations:    
    20. Lauterbach AL, Wallace RP, Alpar AT, Refvik KC, Reda JW, Ishihara A, Beckman TN, Slezak AJ, Mizukami Y, Mansurov A, Gomes S, Ishihara J, Hubbell JA. Topically-applied collagen-binding serum albumin-fused interleukin-4 modulates wound microenvironment in non-healing wounds. NPJ Regen Med. 2023 Sep 11; 8(1):49. PMID: 37696884; PMCID: PMC10495343.
      Citations: 1     
    21. Schnorenberg MR, Hawley KM, Thomas-Toth AT, Watkins EA, Tian Y, Ting JM, Leak LB, Kucera IM, Raczy MM, Kung AL, Hubbell JA, Tirrell MV, LaBelle JL. Targeted Polymersome Delivery of a Stapled Peptide for Drugging the Tumor Protein p53:BCL-2-Family Axis in Diffuse Large B-Cell Lymphoma. ACS Nano. 2023 12 12; 17(23):23374-23390. PMID: 37688780; PMCID: PMC10722602.
      Citations: 4     Fields:    Translation:HumansCells
    22. Tremain AC, Wallace RP, Lorentz KM, Thornley TB, Antane JT, Raczy MR, Reda JW, Alpar AT, Slezak AJ, Watkins EA, Maulloo CD, Budina E, Solanki A, Nguyen M, Bischoff DJ, Harrington JL, Mishra R, Conley GP, Marlin R, Dereuddre-Bosquet N, Gallouët AS, LeGrand R, Wilson DS, Kontos S, Hubbell JA. Synthetically glycosylated antigens for the antigen-specific suppression of established immune responses. Nat Biomed Eng. 2023 09; 7(9):1142-1155. PMID: 37679570.
      Citations: 15     Fields:    Translation:AnimalsCells
    23. Lauterbach AL, Slezak AJ, Wang R, Cao S, Raczy MM, Watkins EA, Jimenez CJM, Hubbell JA. Mannose-Decorated Co-Polymer Facilitates Controlled Release of Butyrate to Accelerate Chronic Wound Healing. Adv Healthc Mater. 2023 10; 12(26):e2300515. PMID: 37503634; PMCID: PMC11468131.
      Citations: 4     Fields:    Translation:Humans
    24. Li N, Li Y, Cheng Z, Liu Y, Dai Y, Kang S, Li S, Shan N, Wai S, Ziaja A, Wang Y, Strzalka J, Liu W, Zhang C, Gu X, Hubbell JA, Tian B, Wang S. Bioadhesive polymer semiconductors and transistors for intimate biointerfaces. Science. 2023 08 11; 381(6658):686-693. PMID: 37561870; PMCID: PMC10768720.
      Citations: 22     Fields:    Translation:Animals
    25. Goldberger Z, Hauert S, Chang K, Kurtanich T, Alpar AT, Repond G, Wang Y, Gomes S, Krishnakumar R, Siddarth P, Swartz MA, Hubbell JA, Briquez PS. Membrane-localized neoantigens predict the efficacy of cancer immunotherapy. Cell Rep Med. 2023 08 15; 4(8):101145. PMID: 37552990; PMCID: PMC10439248.
      Citations: 1     Fields:    Translation:HumansAnimals
    26. Li Y, Li N, Liu W, Prominski A, Kang S, Dai Y, Liu Y, Hu H, Wai S, Dai S, Cheng Z, Su Q, Cheng P, Wei C, Jin L, Hubbell JA, Tian B, Wang S. Achieving tissue-level softness on stretchable electronics through a generalizable soft interlayer design. Nat Commun. 2023 07 26; 14(1):4488. PMID: 37495580; PMCID: PMC10372055.
      Citations: 13     Fields:    Translation:Humans
    27. Grosso A, Lunger A, Burger MG, Briquez PS, Mai F, Hubbell JA, Schaefer DJ, Banfi A, Di Maggio N. VEGF dose controls the coupling of angiogenesis and osteogenesis in engineered bone. NPJ Regen Med. 2023 Mar 13; 8(1):15. PMID: 36914692; PMCID: PMC10011536.
      Citations: 17     
    28. Wang R, Cao S, Bashir MEH, Hesser LA, Su Y, Hong SMC, Thompson A, Culleen E, Sabados M, Dylla NP, Campbell E, Bao R, Nonnecke EB, Bevins CL, Wilson DS, Hubbell JA, Nagler CR. Treatment of peanut allergy and colitis in mice via the intestinal release of butyrate from polymeric micelles. Nat Biomed Eng. 2023 Jan; 7(1):38-55. PMID: 36550307; PMCID: PMC9870785.
      Citations: 35     Fields:    Translation:Animals
    29. Briquez PS, Rouhani SJ, Yu J, Pyzer AR, Trujillo J, Dugan HL, Stamper CT, Changrob S, Sperling AI, Wilson PC, Gajewski TF, Hubbell JA, Swartz MA. Severe COVID-19 induces autoantibodies against angiotensin II that correlate with blood pressure dysregulation and disease severity. Sci Adv. 2022 10 07; 8(40):eabn3777. PMID: 36206332; PMCID: PMC9544317.
      Citations: 20     Fields:    Translation:HumansCells
    30. Slezak AJ, Mansurov A, Raczy MM, Chang K, Alpar AT, Lauterbach AL, Wallace RP, Weathered RK, Medellin JEG, Battistella C, Gray LT, Marchell TM, Gomes S, Swartz MA, Hubbell JA. Tumor Cell-Surface Binding of Immune Stimulating Polymeric Glyco-Adjuvant via Cysteine-Reactive Pyridyl Disulfide Promotes Antitumor Immunity. ACS Cent Sci. 2022 Oct 26; 8(10):1435-1446. PMID: 36313164; PMCID: PMC9615125.
      Citations: 9     
    31. D'Amico R, Malucelli C, Uccelli A, Grosso A, Di Maggio N, Briquez PS, Hubbell JA, Wolff T, Mujagic E, Gianni-Barrera R, Banfi A, Gürke L. Therapeutic arteriogenesis by factor-decorated fibrin matrices promotes wound healing in diabetic mice. J Tissue Eng. 2022 Jan-Dec; 13:20417314221119615. PMID: 36093431; PMCID: PMC9452813.
      Citations: 4     
    32. Weiss AM, Hossainy S, Rowan SJ, Hubbell JA, Esser-Kahn AP. Immunostimulatory Polymers as Adjuvants, Immunotherapies, and Delivery Systems. Macromolecules. 2022 Aug 23; 55(16):6913-6937. PMID: 36034324; PMCID: PMC9404695.
      Citations: 17     Fields:    
    33. Burger MG, Grosso A, Briquez PS, Born GME, Lunger A, Schrenk F, Todorov A, Sacchi V, Hubbell JA, Schaefer DJ, Banfi A, Di Maggio N. Robust coupling of angiogenesis and osteogenesis by VEGF-decorated matrices for bone regeneration. Acta Biomater. 2022 09 01; 149:111-125. PMID: 35835287.
      Citations: 27     Fields:    Translation:HumansCells
    34. Liu J, Solanki A, White MJV, Hubbell JA, Briquez PS. Therapeutic use of a2-antiplasmin as an antifibrinolytic and hemostatic agent in surgery and regenerative medicine. NPJ Regen Med. 2022 Jun 30; 7(1):34. PMID: 35773290; PMCID: PMC9246914.
      Citations: 5     
    35. Mansurov A, Hosseinchi P, Chang K, Lauterbach AL, Gray LT, Alpar AT, Budina E, Slezak AJ, Kang S, Cao S, Solanki A, Gomes S, Williford JM, Swartz MA, Mendoza JL, Ishihara J, Hubbell JA. Masking the immunotoxicity of interleukin-12 by fusing it with a domain of its receptor via a tumour-protease-cleavable linker. Nat Biomed Eng. 2022 07; 6(7):819-829. PMID: 35534574; PMCID: PMC11155269.
      Citations: 25     Fields:    Translation:Animals
    36. Naved BA, Bonventre JV, Hubbell JA, Hukriede NA, Humphreys BD, Kesselman C, Valerius MT, McMahon AP, Shankland SJ, Wertheim JA, White MJV, de Caestecker MP, Drummond IA. Kidney repair and regeneration: perspectives of the NIDDK (Re)Building a Kidney consortium. Kidney Int. 2022 05; 101(5):845-853. PMID: 35276204; PMCID: PMC9045003.
      Citations: 20     Fields:    Translation:Humans
    37. White MJV, Briquez PS, White DAV, Hubbell JA. VEGF-A, PDGF-BB and HB-EGF engineered for promiscuous super affinity to the extracellular matrix improve wound healing in a model of type 1 diabetes. NPJ Regen Med. 2021 Nov 18; 6(1):76. PMID: 34795305; PMCID: PMC8602425.
      Citations: 25     
    38. Briquez PS, Rouhani SJ, Yu J, Pyzer AR, Trujillo J, Dugan HL, Stamper CT, Changrob S, Sperling AI, Wilson PC, Gajewski TF, Hubbell JA, Swartz MA. SARS-CoV-2 infection induces cross-reactive autoantibodies against angiotensin II. medRxiv. 2021 Nov 02. PMID: 34751272; PMCID: PMC8575143.
      Citations:    
    39. Yu SS, Hubbell JA, Swartz MA. Overcoming transport barriers to immunotherapy. Drug Deliv Transl Res. 2021 12; 11(6):2273-2275. PMID: 34718959; PMCID: PMC10994393.
      Citations:    Fields:    
    40. Gray LT, Raczy MM, Briquez PS, Marchell TM, Alpar AT, Wallace RP, Volpatti LR, Sasso MS, Cao S, Nguyen M, Mansurov A, Budina E, Watkins EA, Solanki A, Mitrousis N, Reda JW, Yu SS, Tremain AC, Wang R, Nicolaescu V, Furlong K, Dvorkin S, Manicassamy B, Randall G, Wilson DS, Kwissa M, Swartz MA, Hubbell JA. Generation of potent cellular and humoral immunity against SARS-CoV-2 antigens via conjugation to a polymeric glyco-adjuvant. Biomaterials. 2021 11; 278:121159. PMID: 34634664; PMCID: PMC8482845.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    41. Maulloo CD, Cao S, Watkins EA, Raczy MM, Solanki AS, Nguyen M, Reda JW, Shim HN, Wilson DS, Swartz MA, Hubbell JA. Lymph Node-Targeted Synthetically Glycosylated Antigen Leads to Antigen-Specific Immunological Tolerance. Front Immunol. 2021; 12:714842. PMID: 34630389; PMCID: PMC8498032.
      Citations: 7     Fields:    Translation:AnimalsCells
    42. Volpatti LR, Wallace RP, Cao S, Raczy MM, Wang R, Gray LT, Alpar AT, Briquez PS, Mitrousis N, Marchell TM, Sasso MS, Nguyen M, Mansurov A, Budina E, Solanki A, Watkins EA, Schnorenberg MR, Tremain AC, Reda JW, Nicolaescu V, Furlong K, Dvorkin S, Yu SS, Manicassamy B, LaBelle JL, Tirrell MV, Randall G, Kwissa M, Swartz MA, Hubbell JA. Polymersomes Decorated with the SARS-CoV-2 Spike Protein Receptor-Binding Domain Elicit Robust Humoral and Cellular Immunity. ACS Cent Sci. 2021 Aug 25; 7(8):1368-1380. PMID: 34466656; PMCID: PMC8315245.
      Citations: 15     
    43. Mansurov A, Lauterbach A, Budina E, Alpar AT, Hubbell JA, Ishihara J. Immunoengineering approaches for cytokine therapy. Am J Physiol Cell Physiol. 2021 08 01; 321(2):C369-C383. PMID: 34232748.
      Citations: 12     Fields:    Translation:HumansAnimals
    44. Certelli A, Valente P, Uccelli A, Grosso A, Di Maggio N, D'Amico R, Briquez PS, Hubbell JA, Wolff T, Mujagic E, Gianni-Barrera R, Banfi A, Gürke L. Robust Angiogenesis and Arteriogenesis in the Skin of Diabetic Mice by Transient Delivery of Engineered VEGF and PDGF-BB Proteins in Fibrin Hydrogels. Front Bioeng Biotechnol. 2021; 9:688467. PMID: 34277588; PMCID: PMC8281302.
      Citations: 18     
    45. Briquez PS, Tsai HM, Watkins EA, Hubbell JA. Engineered bridge protein with dual affinity for bone morphogenetic protein-2 and collagen enhances bone regeneration for spinal fusion. Sci Adv. 2021 06; 7(24). PMID: 34117071; PMCID: PMC8195475.
      Citations: 15     Fields:    Translation:Animals
    46. Volpatti LR, Wallace RP, Cao S, Raczy MM, Wang R, Gray LT, Alpar AT, Briquez PS, Mitrousis N, Marchell TM, Sasso MS, Nguyen M, Mansurov A, Budina E, Solanki A, Watkins EA, Schnorenberg MR, Tremain AC, Reda JW, Nicolaescu V, Furlong K, Dvorkin S, Yu SS, Manicassamy B, LaBelle JL, Tirrell MV, Randall G, Kwissa M, Swartz MA, Hubbell JA. Polymersomes decorated with SARS-CoV-2 spike protein receptor binding domain elicit robust humoral and cellular immunity. bioRxiv. 2021 Apr 08. PMID: 33851166; PMCID: PMC8043456.
      Citations:    
    47. Sasso MS, Mitrousis N, Wang Y, Briquez PS, Hauert S, Ishihara J, Hubbell JA, Swartz MA. Lymphangiogenesis-inducing vaccines elicit potent and long-lasting T cell immunity against melanomas. Sci Adv. 2021 03; 7(13). PMID: 33762337; PMCID: PMC7990326.
      Citations: 31     Fields:    Translation:AnimalsCells
    48. Yuba E, Budina E, Katsumata K, Ishihara A, Mansurov A, Alpar AT, Watkins EA, Hosseinchi P, Reda JW, Lauterbach AL, Nguyen M, Solanki A, Kageyama T, Swartz MA, Ishihara J, Hubbell JA. Suppression of Rheumatoid Arthritis by Enhanced Lymph Node Trafficking of Engineered Interleukin-10 in Murine Models. Arthritis Rheumatol. 2021 05; 73(5):769-778. PMID: 33169522; PMCID: PMC11095083.
      Citations: 12     Fields:    Translation:AnimalsCells
    49. Damo M, Wilson DS, Watkins EA, Hubbell JA. Soluble N-Acetylgalactosamine-Modified Antigens Enhance Hepatocyte-Dependent Antigen Cross-Presentation and Result in Antigen-Specific CD8+ T Cell Tolerance Development. Front Immunol. 2021; 12:555095. PMID: 33746941; PMCID: PMC7965950.
      Citations: 7     Fields:    Translation:AnimalsCells
    50. Watkins EA, Antane JT, Roberts JL, Lorentz KM, Zuerndorfer S, Dunaif AC, Bailey LJ, Tremain AC, Nguyen M, De Loera RC, Wallace RP, Weathered RK, Kontos S, Hubbell JA. Persistent antigen exposure via the eryptotic pathway drives terminal T cell dysfunction. Sci Immunol. 2021 02 26; 6(56). PMID: 33637595.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    51. Ishihara A, Ishihara J, Watkins EA, Tremain AC, Nguyen M, Solanki A, Katsumata K, Mansurov A, Budina E, Alpar AT, Hosseinchi P, Maillat L, Reda JW, Kageyama T, Swartz MA, Yuba E, Hubbell JA. Publisher Correction: Prolonged residence of an albumin-IL-4 fusion protein in secondary lymphoid organs ameliorates experimental autoimmune encephalomyelitis. Nat Biomed Eng. 2020 Nov; 4(11):1117. PMID: 33093659.
      Citations: 1     Fields:    
    52. Ishihara A, Ishihara J, Watkins EA, Tremain AC, Nguyen M, Solanki A, Katsumata K, Mansurov A, Budina E, Alpar AT, Hosseinchi P, Maillat L, Reda JW, Kageyama T, Swartz MA, Yuba E, Hubbell JA. Prolonged residence of an albumin-IL-4 fusion protein in secondary lymphoid organs ameliorates experimental autoimmune encephalomyelitis. Nat Biomed Eng. 2021 05; 5(5):387-398. PMID: 33046864.
      Citations: 16     Fields:    Translation:AnimalsCells
    53. Romero P, Donda A, Hubbell JA. An optimized antigen-protein fusion. Nat Biomed Eng. 2020 06; 4(6):583-584. PMID: 32533123.
      Citations: 4     Fields:    Translation:Cells
    54. Mansurov A, Ishihara J, Hosseinchi P, Potin L, Marchell TM, Ishihara A, Williford JM, Alpar AT, Raczy MM, Gray LT, Swartz MA, Hubbell JA. Collagen-binding IL-12 enhances tumour inflammation and drives the complete remission of established immunologically cold mouse tumours. Nat Biomed Eng. 2020 05; 4(5):531-543. PMID: 32284554; PMCID: PMC11095084.
      Citations: 92     Fields:    Translation:AnimalsCells
    55. Briquez PS, Hauert S, Gray LT, Alpar AT, Swartz MA, Hubbell JA, de Titta A. Engineering Targeting Materials for Therapeutic Cancer Vaccines. Front Bioeng Biotechnol. 2020; 8:19. PMID: 32117911; PMCID: PMC7026271.
      Citations: 13     
    56. Katsumata K, Ishihara J, Fukunaga K, Ishihara A, Yuba E, Budina E, Hubbell JA. Conferring extracellular matrix affinity enhances local therapeutic efficacy of anti-TNF-a antibody in a murine model of rheumatoid arthritis. Arthritis Res Ther. 2019 12 23; 21(1):298. PMID: 31870429; PMCID: PMC6929495.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    57. Williford JM, Ishihara J, Ishihara A, Mansurov A, Hosseinchi P, Marchell TM, Potin L, Swartz MA, Hubbell JA. Recruitment of CD103+ dendritic cells via tumor-targeted chemokine delivery enhances efficacy of checkpoint inhibitor immunotherapy. Sci Adv. 2019 12; 5(12):eaay1357. PMID: 31844672; PMCID: PMC6905870.
      Citations: 63     Fields:    Translation:HumansAnimalsCells
    58. Katsumata K, Ishihara J, Mansurov A, Ishihara A, Raczy MM, Yuba E, Hubbell JA. Targeting inflammatory sites through collagen affinity enhances the therapeutic efficacy of anti-inflammatory antibodies. Sci Adv. 2019 11; 5(11):eaay1971. PMID: 31723606; PMCID: PMC6834392.
      Citations: 23     Fields:    Translation:HumansAnimals
    59. Mochizuki M, Park AJ, Julier Z, Güç E, Briquez PS, Kuhn GA, Müller R, Swartz MA, Hubbell JA, Martino MM. Growth factors with enhanced syndecan binding generate tonic signalling and promote tissue healing. Nat Biomed Eng. 2020 04; 4(4):463-475. PMID: 31685999.
      Citations: 35     Fields:    Translation:HumansAnimalsCells
    60. Licht C, Rose JC, Anarkoli AO, Gehlen DB, Hubbell JA, De Laporte L, Blondel D, Roccio M, Haraszti T, Lutolf MP. Synthetic 3D PEG-Anisogel Tailored with Fibronectin Fragments Induce Aligned Nerve Extension. Biomacromolecules. 2019 11 11; 20(11):4075-4087. PMID: 31614080.
      Citations: 18     Fields:    Translation:HumansCells
    61. Sasaki K, Ishihara J, Ishihara A, Miura R, Mansurov A, Fukunaga K, Hubbell JA. Engineered collagen-binding serum albumin as a drug conjugate carrier for cancer therapy. Sci Adv. 2019 08; 5(8):eaaw6081. PMID: 31453327; PMCID: PMC6693903.
      Citations: 26     Fields:    Translation:AnimalsCells
    62. Wilson DS, Damo M, Raczy MM, Hubbell JA, Hirosue S, Brünggel K, Diaceri G, Quaglia-Thermes X. Synthetically glycosylated antigens induce antigen-specific tolerance and prevent the onset of diabetes. Nat Biomed Eng. 2019 10; 3(10):817-829. PMID: 31358881.
      Citations: 29     Fields:    Translation:AnimalsCells
    63. Ishihara J, Ishihara A, Starke RD, Peghaire CR, Smith KE, McKinnon TAJ, Sasaki K, White MJV, Fukunaga K, Laffan MA, Randi AM, Hubbell JA, Tabata Y, Lutolf MP. The heparin binding domain of von Willebrand factor binds to growth factors and promotes angiogenesis in wound healing. Blood. 2019 06 13; 133(24):2559-2569. PMID: 30975637; PMCID: PMC6566593.
      Citations: 51     Fields:    Translation:AnimalsCells
    64. Ishihara J, Ishihara A, Sasaki K, Lee SS, Williford JM, Yasui M, Abe H, Potin L, Hosseinchi P, Fukunaga K, Raczy MM, Gray LT, Mansurov A, Katsumata K, Fukayama M, Kron SJ, Swartz MA, Hubbell JA. Targeted antibody and cytokine cancer immunotherapies through collagen affinity. Sci Transl Med. 2019 04 10; 11(487). PMID: 30971453; PMCID: PMC6541444.
      Citations: 81     Fields:    Translation:HumansAnimalsCells
    65. Pinnagoda K, Zambelli PY, Hubbell JA, Vardar E, Vythilingam G, Engelhardt EM, Lutolf MP, Frey P, Larsson HM. A bioactive injectable bulking material; a potential therapeutic approach for stress urinary incontinence. Biomaterials. 2019 06; 206:41-48. PMID: 30925287.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    66. Hubbell JA, Swartz MA. Trojan horses for immunotherapy. Nat Nanotechnol. 2019 03; 14(3):196-197. PMID: 30692676.
      Citations: 5     Fields:    Translation:Humans
    67. Botelho NK, Tschumi BO, Hubbell JA, Swartz MA, Donda A, Romero P. Combination of Synthetic Long Peptides and XCL1 Fusion Proteins Results in Superior Tumor Control. Front Immunol. 2019; 10:294. PMID: 30863405; PMCID: PMC6399421.
      Citations: 19     Fields:    Translation:AnimalsCellsPHPublic Health
    68. Zielinski MS, Hubbell JA, Vardar E, Vythilingam G, Engelhardt EM, Frey P, Larsson HM. Quantitative intrinsic auto-cathodoluminescence can resolve spectral signatures of tissue-isolated collagen extracellular matrix. Commun Biol. 2019; 2:69. PMID: 30793047; PMCID: PMC6379429.
      Citations: 2     Translation:HumansAnimalsCells
    69. Lih E, Park W, Park KW, Chun SY, Kim H, Joung YK, Kwon TG, Hubbell JA, Han DK. A Bioinspired Scaffold with Anti-Inflammatory Magnesium Hydroxide and Decellularized Extracellular Matrix for Renal Tissue Regeneration. ACS Cent Sci. 2019 Mar 27; 5(3):458-467. PMID: 30937373; PMCID: PMC6439446.
      Citations: 34     
    70. Wang R, Kwissa M, Wilson DS, Hirosue S, Raczy MM, Bonilla-Ramirez L, Jeanbart L, Franetich JF, Broggi MAS, Diaceri G, Quaglia-Thermes X, Mazier D, Swartz MA, Hubbell JA. Antigens reversibly conjugated to a polymeric glyco-adjuvant induce protective humoral and cellular immunity. Nat Mater. 2019 02; 18(2):175-185. PMID: 30643235.
      Citations: 95     Fields:    Translation:Animals
    71. Ishihara J, Ishihara A, Potin L, Hosseinchi P, Fukunaga K, Damo M, Gajewski TF, Swartz MA, Hubbell JA. Improving Efficacy and Safety of Agonistic Anti-CD40 Antibody Through Extracellular Matrix Affinity. Mol Cancer Ther. 2018 11; 17(11):2399-2411. PMID: 30097487.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    72. Sothilingam S, Thambidorai RC, Kamarul T, Larsson HM, Vythilingam G, Pinnagoda K, Vardar E, Engelhardt EM, Hubbell JA, Frey P. Fiber density of collagen grafts impacts rabbit urethral regeneration. Sci Rep. 2018 07 03; 8(1):10057. PMID: 29968749; PMCID: PMC6030124.
      Citations: 5     Fields:    Translation:AnimalsCells
    73. Lih E, Kum CH, Park W, Chun SY, Cho Y, Joung YK, Park KS, Hong YJ, Ahn DJ, Kim BS, Kwon TG, Jeong MH, Hubbell JA, Han DK. Modified Magnesium Hydroxide Nanoparticles Inhibit the Inflammatory Response to Biodegradable Poly(lactide- co-glycolide) Implants. ACS Nano. 2018 07 24; 12(7):6917-6925. PMID: 29812907.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    74. Ishihara J, Ishihara A, Fukunaga K, Sasaki K, White MJV, Briquez PS, Hubbell JA. Laminin heparin-binding peptides bind to several growth factors and enhance diabetic wound healing. Nat Commun. 2018 06 04; 9(1):2163. PMID: 29867149; PMCID: PMC5986797.
      Citations: 76     Fields:    Translation:HumansAnimalsCells
    75. Guo AZ, Sevgen E, Sidky H, Whitmer JK, Hubbell JA, de Pablo JJ. Adaptive enhanced sampling by force-biasing using neural networks. J Chem Phys. 2018 Apr 07; 148(13):134108. PMID: 29626875.
      Citations: 5     Fields:    
    76. Manzoli V, Villa C, Bayer AL, Morales LC, Molano RD, Ricordi C, Hubbell JA, Tomei AA, Torrente Y. Immunoisolation of murine islet allografts in vascularized sites through conformal coating with polyethylene glycol. Am J Transplant. 2018 03; 18(3):590-603. PMID: 29068143; PMCID: PMC5820142.
      Citations: 24     Fields:    Translation:Animals
    77. Pinnagoda K, Vythilingam G, Hubbell JA, Vardar E, Larsson HM, Allazetta S, Engelhardt EM, Lutolf MP, Frey P. Microfluidic production of bioactive fibrin micro-beads embedded in crosslinked collagen used as an injectable bulking agent for urinary incontinence treatment. Acta Biomater. 2018 02; 67:156-166. PMID: 29197579.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    78. Ishihara J, Fukunaga K, Ishihara A, Potin L, Hosseinchi P, Swartz MA, Hubbell JA, Larsson HM, Galliverti G. Matrix-binding checkpoint immunotherapies enhance antitumor efficacy and reduce adverse events. Sci Transl Med. 2017 Nov 08; 9(415). PMID: 29118259.
      Citations: 75     Fields:    Translation:AnimalsCells
    79. Ollmann Saphire E, Kunz S, Galan-Navarro C, Rincon-Restrepo M, Zimmer G, Hubbell JA, Hirosue S, Swartz MA. Oxidation-sensitive polymersomes as vaccine nanocarriers enhance humoral responses against Lassa virus envelope glycoprotein. Virology. 2017 12; 512:161-171. PMID: 28963882.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    80. Baekkeskov S, Hubbell JA, Phelps EA. Bioengineering strategies for inducing tolerance in autoimmune diabetes. Adv Drug Deliv Rev. 2017 05 15; 114:256-265. PMID: 28625830.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    81. Phelps EA, Cianciaruso C, Santo-Domingo J, Pasquier M, Galliverti G, Piemonti L, Berishvili E, Burri O, Wiederkehr A, Hubbell JA, Baekkeskov S. Corrigendum: Advances in pancreatic islet monolayer culture on glass surfaces enable super-resolution microscopy and insights into beta cell ciliogenesis and proliferation. Sci Rep. 2017 05 09; 7:46801. PMID: 28485397; PMCID: PMC5422918.
      Citations:    Fields:    
    82. Larsson HM, Briquez PS, Lorentz KM, Frey P, Hubbell JA. Human Kunitz-type protease inhibitor engineered for enhanced matrix retention extends longevity of fibrin biomaterials. Biomaterials. 2017 Aug; 135:1-9. PMID: 28477492; PMCID: PMC5702589.
      Citations: 3     Fields:    Translation:Humans
    83. Piemonti L, Berishvili E, Phelps EA, Cianciaruso C, Santo-Domingo J, Pasquier M, Galliverti G, Burri O, Wiederkehr A, Hubbell JA, Baekkeskov S. Advances in pancreatic islet monolayer culture on glass surfaces enable super-resolution microscopy and insights into beta cell ciliogenesis and proliferation. Sci Rep. 2017 04 12; 7:45961. PMID: 28401888; PMCID: PMC5388888.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    84. Rincon-Restrepo M, Mayer A, Hauert S, Bonner DK, Phelps EA, Hubbell JA, Swartz MA, Hirosue S. Vaccine nanocarriers: Coupling intracellular pathways and cellular biodistribution to control CD4 vs CD8 T cell responses. Biomaterials. 2017 07; 132:48-58. PMID: 28407494.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    85. Kilarski WW, Güç E, Briquez PS, Foretay D, Fankhauser MA, Hubbell JA, Swartz MA. Local induction of lymphangiogenesis with engineered fibrin-binding VEGF-C promotes wound healing by increasing immune cell trafficking and matrix remodeling. Biomaterials. 2017 07; 131:160-175. PMID: 28410495.
      Citations: 56     Fields:    Translation:HumansAnimalsCells
    86. Dowling DJ, Scott EA, Scheid A, Bergelson I, Joshi S, Pietrasanta C, Brightman S, Sanchez-Schmitz G, Van Haren SD, Ninkovic J, Kats D, Guiducci C, Levy O, de Titta A, Bonner DK, Hirosue S, Swartz MA, Hubbell JA. Toll-like receptor 8 agonist nanoparticles mimic immunomodulating effects of the live BCG vaccine and enhance neonatal innate and adaptive immune responses. J Allergy Clin Immunol. 2017 Nov; 140(5):1339-1350. PMID: 28343701; PMCID: PMC5667586.
      Citations: 74     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    87. Oxburgh L, Carroll TJ, Cleaver O, Gossett DR, Hoshizaki DK, Hubbell JA, Humphreys BD, Jain S, Jensen J, Kaplan DL, Kesselman C, Ketchum CJ, Little MH, McMahon AP, Shankland SJ, Spence JR, Valerius MT, Wertheim JA, Wessely O, Zheng Y, Drummond IA. (Re)Building a Kidney. J Am Soc Nephrol. 2017 May; 28(5):1370-1378. PMID: 28096308; PMCID: PMC5407737.
      Citations: 33     Fields:    Translation:HumansCells
    88. Alibashe Ahmed M, Piemonti L, Cianciaruso C, Phelps EA, Pasquier M, Hamelin R, Demurtas D, Hirosue S, Swartz MA, De Palma M, Hubbell JA, Baekkeskov S. Primary Human and Rat ß-Cells Release the Intracellular Autoantigens GAD65, IA-2, and Proinsulin in Exosomes Together With Cytokine-Induced Enhancers of Immunity. Diabetes. 2017 02; 66(2):460-473. PMID: 27872147.
      Citations: 102     Fields:    Translation:HumansAnimalsCells
    89. Lee M, Ahn JI, Ahn JY, Yang WS, Lim JM, Lee ST, Hubbell JA. Difference in suitable mechanical properties of three-dimensional, synthetic scaffolds for self-renewing mouse embryonic stem cells of different genetic backgrounds. J Biomed Mater Res B Appl Biomater. 2017 Nov; 105(8):2261-2268. PMID: 27459401.
      Citations: 1     Fields:    Translation:AnimalsCells
    90. Thambidorai RC, Pinnagoda K, Larsson HM, Vythilingam G, Vardar E, Engelhardt EM, Hubbell JA, Frey P. Engineered acellular collagen scaffold for endogenous cell guidance, a novel approach in urethral regeneration. Acta Biomater. 2016 10 01; 43:208-217. PMID: 27450527.
      Citations: 25     Fields:    Translation:Animals
    91. Kanaani J, Nano R, Lavallard V, Billestrup N, Phelps EA, Cianciaruso C, Michael IP, Pasquier M, Hubbell JA, Baekkeskov S. Aberrant Accumulation of the Diabetes Autoantigen GAD65 in Golgi Membranes in Conditions of ER Stress and Autoimmunity. Diabetes. 2016 09; 65(9):2686-99. PMID: 27284108; PMCID: PMC5001175.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    92. Vardar E, Larsson HM, Engelhardt EM, Pinnagoda K, Briquez PS, Hubbell JA, Frey P. IGF-1-containing multi-layered collagen-fibrin hybrid scaffolds for bladder tissue engineering. Acta Biomater. 2016 09 01; 41:75-85. PMID: 27286676.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    93. Julier Z, de Titta A, Grimm AJ, Simeoni E, Swartz MA, Hubbell JA. Fibronectin EDA and CpG synergize to enhance antigen-specific Th1 and cytotoxic responses. Vaccine. 2016 05 05; 34(21):2453-2459. PMID: 27016652; PMCID: PMC4859824.
      Citations: 6     Fields:    Translation:AnimalsCellsPHPublic Health
    94. Zielinski MS, Choi JW, La Grange T, Modestino M, Hashemi SM, Pu Y, Birkhold S, Hubbell JA, Psaltis D. Hollow Mesoporous Plasmonic Nanoshells for Enhanced Solar Vapor Generation. Nano Lett. 2016 Apr 13; 16(4):2159-67. PMID: 26918518.
      Citations: 24     Fields:    
    95. Brubaker CE, Panagiotou V, Demurtas D, Bonner DK, Swartz MA, Hubbell JA. A Cationic Micelle Complex Improves CD8+ T Cell Responses in Vaccination Against Unmodified Protein Antigen. ACS Biomater Sci Eng. 2016 Feb 08; 2(2):231-240. PMID: 33418636.
      Citations: 7     Fields:    
    96. Damo M, Wilson DS, Simeoni E, Hubbell JA. TLR-3 stimulation improves anti-tumor immunity elicited by dendritic cell exosome-based vaccines in a murine model of melanoma. Sci Rep. 2015 Dec 03; 5:17622. PMID: 26631690; PMCID: PMC4668567.
      Citations: 63     Fields:    Translation:AnimalsCells
    97. Mitchell AC, Cochran JR, Briquez PS, Hubbell JA. Engineering growth factors for regenerative medicine applications. Acta Biomater. 2016 Jan; 30:1-12. PMID: 26555377; PMCID: PMC6067679.
      Citations: 120     Fields:    Translation:HumansAnimals
    98. Grimm AJ, Kontos S, Diaceri G, Quaglia-Thermes X, Hubbell JA. Memory of tolerance and induction of regulatory T cells by erythrocyte-targeted antigens. Sci Rep. 2015 Oct 29; 5:15907. PMID: 26511151; PMCID: PMC4625129.
      Citations: 47     Fields:    Translation:AnimalsCells
    99. Ballester M, Jeanbart L, de Titta A, Nembrini C, Hubbell JA, Swartz MA, Marsland BJ. Nanoparticle conjugation enhances the immunomodulatory effects of intranasally delivered CpG in house dust mite-allergic mice. Sci Rep. 2015 Sep 21; 5:14274. PMID: 26387548; PMCID: PMC4585708.
      Citations: 19     Fields:    Translation:AnimalsCells
    100. Briquez PS, Hubbell JA, Martino MM. Extracellular Matrix-Inspired Growth Factor Delivery Systems for Skin Wound Healing. Adv Wound Care (New Rochelle). 2015 Aug 01; 4(8):479-489. PMID: 26244104; PMCID: PMC4505763.
      Citations: 83     Fields:    
    101. Vardar E, Engelhardt EM, Larsson HM, Mouloungui E, Pinnagoda K, Hubbell JA, Frey P. Tubular Compressed Collagen Scaffolds for Ureteral Tissue Engineering in a Flow Bioreactor System. Tissue Eng Part A. 2015 Sep; 21(17-18):2334-45. PMID: 26065873.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    102. Henry H, Lorentz KM, Kontos S, Diaceri G, Hubbell JA. Engineered binding to erythrocytes induces immunological tolerance to E. coli asparaginase. Sci Adv. 2015 Jul; 1(6):e1500112. PMID: 26601215; PMCID: PMC4646778.
      Citations: 38     Fields:    
    103. Kontos S, Grimm AJ, Hubbell JA. Engineering antigen-specific immunological tolerance. Curr Opin Immunol. 2015 Aug; 35:80-8. PMID: 26163377.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    104. Brubaker CE, Velluto D, Demurtas D, Phelps EA, Hubbell JA. Crystalline Oligo(ethylene sulfide) Domains Define Highly Stable Supramolecular Block Copolymer Assemblies. ACS Nano. 2015 Jul 28; 9(7):6872-81. PMID: 26125494.
      Citations: 6     Fields:    Translation:AnimalsCells
    105. Najjar M, Manzoli V, Abreu M, Villa C, Molano RD, Torrente Y, Pileggi A, Inverardi L, Ricordi C, Hubbell JA, Tomei AA, Martino MM. Fibrin gels engineered with pro-angiogenic growth factors promote engraftment of pancreatic islets in extrahepatic sites in mice. Biotechnol Bioeng. 2015 Sep; 112(9):1916-26. PMID: 25786390.
      Citations: 25     Fields:    Translation:HumansAnimals
    106. Hubbell JA. Prescription for a pharmacyte. Sci Transl Med. 2015 Jun 10; 7(291):291fs23. PMID: 26062842.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    107. Kourtis IC, Swartz MA, Hubbell JA, Jeanbart L, van der Vlies AJ. 6-Thioguanine-loaded polymeric micelles deplete myeloid-derived suppressor cells and enhance the efficacy of T cell immunotherapy in tumor-bearing mice. Cancer Immunol Immunother. 2015 Aug; 64(8):1033-46. PMID: 25982370; PMCID: PMC4506469.
      Citations: 23     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    108. Maruyama K, Martino MM, Briquez PS, Hubbell JA. Extracellular matrix-inspired growth factor delivery systems for bone regeneration. Adv Drug Deliv Rev. 2015 Nov 01; 94:41-52. PMID: 25895621.
      Citations: 83     Fields:    Translation:HumansCells
    109. Brkic S, Bovo E, Burger M, Schaefer DJ, Wolff T, Gianni-Barrera R, Banfi A, Martino MM, Gürke L, Briquez PS, Larsson HM, Hubbell JA. Extracellular matrix and growth factor engineering for controlled angiogenesis in regenerative medicine. Front Bioeng Biotechnol. 2015; 3:45. PMID: 25883933; PMCID: PMC4381713.
      Citations: 72     
    110. Husseinil GA, Kherbeckl L, Pitt WG, Hubbell JA, Christensen DA, Velluto D. Kinetics of Ultrasonic Drug Delivery from Targeted Micelles. J Nanosci Nanotechnol. 2015 Mar; 15(3):2099-104. PMID: 26413626.
      Citations: 2     Fields:    Translation:Cells
    111. Julier Z, Martino MM, de Titta A, Jeanbart L, Hubbell JA. The TLR4 agonist fibronectin extra domain A is cryptic, exposed by elastase-2; use in a fibrin matrix cancer vaccine. Sci Rep. 2015 Feb 24; 5:8569. PMID: 25708982; PMCID: PMC4338432.
      Citations: 28     Fields:    Translation:AnimalsCells
    112. Lin YA, Cui H, Hubbell JA, Reis RL, Azevedo HS, Ferreira DS. Molecularly engineered self-assembling membranes for cell-mediated degradation. Adv Healthc Mater. 2015 Mar 11; 4(4):602-12. PMID: 25413155.
      Citations: 6     Fields:    Translation:HumansCells
    113. Zakrzewski JL, van den Brink MR, Hubbell JA. Overcoming immunological barriers in regenerative medicine. Nat Biotechnol. 2014 Aug; 32(8):786-94. PMID: 25093888; PMCID: PMC4409427.
      Citations: 66     Fields:    Translation:HumansAnimals
    114. Tomei AA, Manzoli V, Fraker CA, Giraldo J, Najjar M, Pileggi A, Molano RD, Ricordi C, Stabler CL, Velluto D, Hubbell JA. Device design and materials optimization of conformal coating for islets of Langerhans. Proc Natl Acad Sci U S A. 2014 Jul 22; 111(29):10514-9. PMID: 24982192; PMCID: PMC4115512.
      Citations: 82     Fields:    Translation:Animals
    115. Vila OF, Rubio N, Martino MM, Nebuloni L, Kuhn G, Pérez-Amodio S, Müller R, Hubbell JA, Blanco J. Bioluminescent and micro-computed tomography imaging of bone repair induced by fibrin-binding growth factors. Acta Biomater. 2014 Oct; 10(10):4377-89. PMID: 24905933.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    116. Sacchi V, Mittermayr R, Hartinger J, Wolbank S, Hofmann A, Largo RA, Marschall JS, Groppa E, Gianni-Barrera R, Ehrbar M, Redl H, Banfi A, Martino MM, Lorentz KM, Hubbell JA. Long-lasting fibrin matrices ensure stable and functional angiogenesis by highly tunable, sustained delivery of recombinant VEGF164. Proc Natl Acad Sci U S A. 2014 May 13; 111(19):6952-7. PMID: 24778233; PMCID: PMC4024904.
      Citations: 60     Fields:    Translation:HumansAnimalsCells
    117. Larsson HM, Gorostidi F, Hubbell JA, Barrandon Y, Frey P. Clonal, self-renewing and differentiating human and porcine urothelial cells, a novel stem cell population. PLoS One. 2014; 9(2):e90006. PMID: 24587183; PMCID: PMC3935977.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    118. Briquez PS, Tortelli F, Kilarski WW, Metzger S, Rice JJ, Kuhn GA, Swartz MA, Hubbell JA, Martino MM, Güç E, Müller R. Growth factors engineered for super-affinity to the extracellular matrix enhance tissue healing. Science. 2014 Feb 21; 343(6173):885-8. PMID: 24558160.
      Citations: 207     Fields:    Translation:HumansAnimalsCells
    119. Ballester M, de Titta A, Romero P, Hubbell JA, Swartz MA, Jeanbart L, Corthésy P. Enhancing efficacy of anticancer vaccines by targeted delivery to tumor-draining lymph nodes. Cancer Immunol Res. 2014 May; 2(5):436-47. PMID: 24795356.
      Citations: 93     Fields:    Translation:HumansAnimalsCells
    120. Ahn JI, Kim GA, Kwon HS, Ahn JY, Hubbell JA, Song YS, Lee ST, Lim JM. Culture of preantral follicles in poly(ethylene) glycol-based, three-dimensional hydrogel: a relationship between swelling ratio and follicular developments. J Tissue Eng Regen Med. 2015 Mar; 9(3):319-23. PMID: 24493269; PMCID: PMC4409103.
      Citations: 7     Fields:    Translation:AnimalsCells
    121. Ballester M, Julier Z, Nembrini C, Jeanbart L, Swartz MA, Hubbell JA, de Titta A, van der Vlies AJ. Nanoparticle conjugation of CpG enhances adjuvancy for cellular immunity and memory recall at low dose. Proc Natl Acad Sci U S A. 2013 Dec 03; 110(49):19902-7. PMID: 24248387; PMCID: PMC3856841.
      Citations: 127     Fields:    Translation:AnimalsCells
    122. Langer R, Hubbell JA. Translating materials design to the clinic. Nat Mater. 2013 Nov; 12(11):963-6. PMID: 24150414.
      Citations: 31     Fields:    Translation:HumansAnimals
    123. Pisano M, Briquez PS, Hubbell JA, Tortelli F, Martino MM. Fibronectin binding modulates CXCL11 activity and facilitates wound healing. PLoS One. 2013; 8(10):e79610. PMID: 24205388; PMCID: PMC3808276.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    124. Vokali E, Lund AW, Hubbell JA, Swartz MA, Thomas SN. Targeting the tumor-draining lymph node with adjuvanted nanoparticles reshapes the anti-tumor immune response. Biomaterials. 2014 Jan; 35(2):814-24. PMID: 24144906.
      Citations: 135     Fields:    Translation:AnimalsCells
    125. Kolb L, Lienemann PS, Hubbell JA, Ehrbar M, Lutolf MP, Mosiewicz KA, van der Vlies AJ, Martino MM. In situ cell manipulation through enzymatic hydrogel photopatterning. Nat Mater. 2013 Nov; 12(11):1072-8. PMID: 24121990.
      Citations: 115     Fields:    Translation:HumansAnimalsCells
    126. Rutkowski JM, Ihm JE, Lee ST, Kilarski WW, Greenwood VI, Pasquier MC, Quazzola A, Trono D, Hubbell JA, Swartz MA. VEGFR-3 neutralization inhibits ovarian lymphangiogenesis, follicle maturation, and murine pregnancy. Am J Pathol. 2013 Nov; 183(5):1596-1607. PMID: 24036251; PMCID: PMC3814520.
      Citations: 17     Fields:    Translation:AnimalsCells
    127. Lee K, Hubbell JA. Tissue, cell and engineering. Curr Opin Biotechnol. 2013 Oct; 24(5):827-9. PMID: 24018131.
      Citations: 4     Fields:    Translation:HumansAnimals
    128. Wandrey C, Hubbell JA, Hasegawa U, van der Vlies AJ. Preparation of well-defined ibuprofen prodrug micelles by RAFT polymerization. Biomacromolecules. 2013 Sep 09; 14(9):3314-20. PMID: 23937521.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    129. Brady AC, Pedraza E, Sukert S, Pileggi A, Ricordi C, Hubbell JA, Stabler CL, Martino MM. Proangiogenic hydrogels within macroporous scaffolds enhance islet engraftment in an extrahepatic site. Tissue Eng Part A. 2013 Dec; 19(23-24):2544-52. PMID: 23790218; PMCID: PMC3856929.
      Citations: 31     Fields:    Translation:Animals
    130. Traub S, Morgner J, Swartz MA, Hubbell JA, Eming SA, Martino MM, Höning S, Wickström SA. The promotion of endothelial cell attachment and spreading using FNIII10 fused to VEGF-A165. Biomaterials. 2013 Aug; 34(24):5958-68. PMID: 23683723.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    131. Hoffmann DC, Willenborg S, Koch M, Zwolanek D, Becker AK, Metzger S, Ehrbar M, Kurschat P, Hellmich M, Hubbell JA, Eming SA, Müller S. Proteolytic processing regulates placental growth factor activities. J Biol Chem. 2013 Jun 21; 288(25):17976-89. PMID: 23645683; PMCID: PMC3689943.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    132. Hirosue S, de Titta A, Kontos S, Stegmann T, Hubbell JA, Swartz MA, Kourtis IC. Peripherally administered nanoparticles target monocytic myeloid cells, secondary lymphoid organs and tumors in mice. PLoS One. 2013; 8(4):e61646. PMID: 23626707; PMCID: PMC3633981.
      Citations: 63     Fields:    Translation:AnimalsCells
    133. Rice JJ, Tortelli F, Hubbell JA, De Laporte L. Tenascin C promiscuously binds growth factors via its fifth fibronectin type III-like domain. PLoS One. 2013; 8(4):e62076. PMID: 23637968; PMCID: PMC3630135.
      Citations: 63     Fields:    Translation:HumansCells
    134. Scott EA, Dane KY, Swartz MA, Hubbell JA, Stano A. Tunable T cell immunity towards a protein antigen using polymersomes vs. solid-core nanoparticles. Biomaterials. 2013 Jun; 34(17):4339-46. PMID: 23478034.
      Citations: 50     Fields:    Translation:AnimalsCells
    135. Briquez PS, Ranga A, Lutolf MP, Hubbell JA, Martino MM. Heparin-binding domain of fibrin(ogen) binds growth factors and promotes tissue repair when incorporated within a synthetic matrix. Proc Natl Acad Sci U S A. 2013 Mar 19; 110(12):4563-8. PMID: 23487783; PMCID: PMC3607046.
      Citations: 198     Fields:    Translation:HumansAnimalsCells
    136. Nembrini C, Stano A, Hubbell JA, Maerkl SJ, Garcia-Cordero JL. A high-throughput nanoimmunoassay chip applied to large-scale vaccine adjuvant screening. Integr Biol (Camb). 2013 Apr; 5(4):650-8. PMID: 23443913.
      Citations: 26     Fields:    Translation:AnimalsCells
    137. Jang M, Lee ST, Kim JW, Yang JH, Yoon JK, Park JC, Ryoo HM, Ahn JY, Hubbell JA, Song YS, Lee G, Lim JM, van der Vlies AJ. A feeder-free, defined three-dimensional polyethylene glycol-based extracellular matrix niche for culture of human embryonic stem cells. Biomaterials. 2013 May; 34(14):3571-80. PMID: 23422594.
      Citations: 22     Fields:    Translation:HumansCells
    138. Kourtis IC, Dane KY, Hubbell JA, Kontos S. Engineering antigens for in situ erythrocyte binding induces T-cell deletion. Proc Natl Acad Sci U S A. 2013 Jan 02; 110(1):E60-8. PMID: 23248266; PMCID: PMC3538192.
      Citations: 101     Fields:    Translation:AnimalsCells
    139. Lee ST, Roccio M, Velluto D, Lutolf MP, Frey P, Hubbell JA, Larsson HM. Sorting live stem cells based on Sox2 mRNA expression. PLoS One. 2012; 7(11):e49874. PMID: 23209609; PMCID: PMC3507951.
      Citations: 16     Fields:    Translation:AnimalsCells
    140. Nembrini C, Swartz MA, Hubbell JA, Simeoni E, Stano A. Nanoparticle size influences the magnitude and quality of mucosal immune responses after intranasal immunization. Vaccine. 2012 Dec 14; 30(52):7541-6. PMID: 23103199.
      Citations: 33     Fields:    Translation:AnimalsCellsPHPublic Health
    141. Ventura M, Hubbell JA, Ossipov DA, Kisiel M, Martino MM, Hilborn J. Improving the osteogenic potential of BMP-2 with hyaluronic acid hydrogel modified with integrin-specific fibronectin fragment. Biomaterials. 2013 Jan; 34(3):704-12. PMID: 23103154.
      Citations: 36     Fields:    Translation:HumansAnimalsCells
    142. Yun JI, van der Vlies AJ, Kontos S, Jang M, Gong SP, Kim DY, Lim JM, Hubbell JA, Lee ST. Long-term maintenance of mouse embryonic stem cell pluripotency by manipulating integrin signaling within 3D scaffolds without active Stat3. Biomaterials. 2012 Dec; 33(35):8934-42. PMID: 22998814.
      Citations: 15     Fields:    Translation:AnimalsCells
    143. Hasegawa U, Hubbell JA, van der Vlies AJ. Reduction-sensitive tioguanine prodrug micelles. Mol Pharm. 2012 Oct 01; 9(10):2812-8. PMID: 22954101.
      Citations: 6     Fields:    Translation:HumansCells
    144. De Laporte L, Tortelli F, Briquez PS, Hubbell JA, Rice JJ, Martino MM. Engineering the regenerative microenvironment with biomaterials. Adv Healthc Mater. 2013 Jan; 2(1):57-71. PMID: 23184739.
      Citations: 122     Fields:    Translation:HumansAnimals
    145. Scott EA, O'Neil CP, Psaltis D, Hubbell JA, Vasdekis AE. Precision intracellular delivery based on optofluidic polymersome rupture. ACS Nano. 2012 Sep 25; 6(9):7850-7. PMID: 22900579.
      Citations: 35     Fields:    Translation:HumansCells
    146. Hirosue S, Hubbell JA, Swartz MA. Engineering approaches to immunotherapy. Sci Transl Med. 2012 Aug 22; 4(148):148rv9. PMID: 22914624.
      Citations: 97     Fields:    Translation:HumansAnimals
    147. Chilkoti A, Hubbell JA. Chemistry. Nanomaterials for drug delivery. Science. 2012 Jul 20; 337(6092):303-5. PMID: 22822138.
      Citations: 100     Fields:    Translation:HumansCells
    148. Arenas da Silva LF, Geutjes PJ, Oosterwijk E, Hubbell JA, Feitz WF, Frey P, Micol LA. In-vivo performance of high-density collagen gel tubes for urethral regeneration in a rabbit model. Biomaterials. 2012 Oct; 33(30):7447-55. PMID: 22795859.
      Citations: 22     Fields:    Translation:Animals
    149. Dane KY, O'Neil CP, Hirosue S, Swartz MA, Hubbell JA, Eby JK. Polymer micelles with pyridyl disulfide-coupled antigen travel through lymphatics and show enhanced cellular responses following immunization. Acta Biomater. 2012 Sep; 8(9):3210-7. PMID: 22698945.
      Citations: 15     Fields:    Translation:Animals
    150. Husseini GA, Velluto D, Kherbeck L, Pitt WG, Hubbell JA, Christensen DA. Investigating the acoustic release of doxorubicin from targeted micelles. Colloids Surf B Biointerfaces. 2013 Jan 01; 101:153-5. PMID: 22796785.
      Citations: 11     Fields:    
    151. Stano A, Gillard M, Maio-Liu AC, Swartz MA, Hubbell JA, Scott EA. Dendritic cell activation and T cell priming with adjuvant- and antigen-loaded oxidation-sensitive polymersomes. Biomaterials. 2012 Sep; 33(26):6211-9. PMID: 22658634.
      Citations: 81     Fields:    Translation:AnimalsCells
    152. Hauwel M, Bei W, Montet-Abou K, Meda P, Gardier S, Zammaretti P, Kraehenbuehl TP, Herrmann F, Hubbell JA, Jaconi ME, Vallée JP, Lepetit-Coiffé M. Embryonic stem cell-based cardiopatches improve cardiac function in infarcted rats. Stem Cells Transl Med. 2012 Mar; 1(3):248-60. PMID: 23197784; PMCID: PMC3659841.
      Citations: 11     Fields:    Translation:AnimalsCells
    153. Yu SS, Lau CM, Thomas SN, Jerome WG, Maron DJ, Dickerson JH, Hubbell JA, Giorgio TD. Size- and charge-dependent non-specific uptake of PEGylated nanoparticles by macrophages. Int J Nanomedicine. 2012; 7:799-813. PMID: 22359457; PMCID: PMC3284223.
      Citations: 55     Fields:    Translation:HumansCells
    154. Hubbell JA, Kontos S. Drug development: longer-lived proteins. Chem Soc Rev. 2012 Apr 07; 41(7):2686-95. PMID: 22310725.
      Citations: 17     Fields:    Translation:Humans
    155. Friedl P, Hubbell J, Livingston D, Mihich E. Twenty-third annual Pezcoller Symposium: engineering influences in cancer research. Cancer Res. 2012 Feb 15; 72(4):841-4. PMID: 22237623.
      Citations:    Fields:    Translation:HumansAnimalsCells
    156. Yang L, Frey P, Hubbell JA, Lorentz KM. Engineered insulin-like growth factor-1 for improved smooth muscle regeneration. Biomaterials. 2012 Jan; 33(2):494-503. PMID: 22014943.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    157. Stano A, Dane KY, Ballester M, Marsland BJ, Swartz MA, Hubbell JA, Nembrini C, van der Vlies AJ. Nanoparticle conjugation of antigen enhances cytotoxic T-cell responses in pulmonary vaccination. Proc Natl Acad Sci U S A. 2011 Nov 01; 108(44):E989-97. PMID: 21969597; PMCID: PMC3207697.
      Citations: 92     Fields:    Translation:AnimalsCells
    158. Thomas SN, Simeoni E, Swartz MA, Hubbell JA, Velluto D. PEG-b-PPS-b-PEI micelles and PEG-b-PPS/PEG-b-PPS-b-PEI mixed micelles as non-viral vectors for plasmid DNA: tumor immunotoxicity in B16F10 melanoma. Biomaterials. 2011 Dec; 32(36):9839-47. PMID: 21924769.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    159. Tortelli F, Mochizuki M, Traub S, Ben-David D, Kuhn GA, Livne E, Eming SA, Hubbell JA, Martino MM, Müller R. Engineering the growth factor microenvironment with fibronectin domains to promote wound and bone tissue healing. Sci Transl Med. 2011 Sep 14; 3(100):100ra89. PMID: 21918106.
      Citations: 203     Fields:    Translation:Animals
    160. Veneziale RW, Kishnani NS, Nelson J, Resendez JC, Frank DW, Cai XY, Xie L, Cullen C, Frugone CA, Rosenfeld C, Hubbell J, Maxwell SE, Sugarman BJ, Hutchins B, Maneval D, Treinen KA. Toxicity and exposure of an adenovirus containing human interferon alpha-2b following intracystic administration in cynomolgus monkeys. Gene Ther. 2012 Jul; 19(7):742-51. PMID: 21900961.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    161. Nembrini C, Tomei AA, Eby JK, O'Neil CP, Velluto D, Swartz MA, Inverardi L, Hubbell JA, Dane KY. Nano-sized drug-loaded micelles deliver payload to lymph node immune cells and prolong allograft survival. J Control Release. 2011 Dec 10; 156(2):154-60. PMID: 21864593.
      Citations: 45     Fields:    Translation:AnimalsCells
    162. Nembrini C, Dhar N, de Titta A, de Piano C, Pasquier M, Simeoni E, McKinney JD, Hubbell JA, Swartz MA, Ballester M, van der Vlies AJ. Nanoparticle conjugation and pulmonary delivery enhance the protective efficacy of Ag85B and CpG against tuberculosis. Vaccine. 2011 Sep 16; 29(40):6959-66. PMID: 21787826.
      Citations: 48     Fields:    Translation:AnimalsCells
    163. Hubbell JA, Eming SA. Extracellular matrix in angiogenesis: dynamic structures with translational potential. Exp Dermatol. 2011 Jul; 20(7):605-13. PMID: 21692861.
      Citations: 24     Fields:    Translation:HumansAnimalsCells
    164. Micol LA, Houis S, Wurm FM, Hubbell JA, Frey P, Engelhardt EM, Hilborn J. A collagen-poly(lactic acid-co-?-caprolactone) hybrid scaffold for bladder tissue regeneration. Biomaterials. 2011 Jun; 32(16):3969-76. PMID: 21377203.
      Citations: 28     Fields:    Translation:HumansAnimalsCells
    165. Yu SS, Scherer RL, Ortega RA, Bell CS, O'Neil CP, Hubbell JA, Giorgio TD. Enzymatic- and temperature-sensitive controlled release of ultrasmall superparamagnetic iron oxides (USPIOs). J Nanobiotechnology. 2011 Feb 27; 9:7. PMID: 21352596; PMCID: PMC3056743.
      Citations: 9     Fields:    
    166. Velluto D, Hubbell JA, Fontana A, Di Crescenzo A. Biocompatible dispersions of carbon nanotubes: a potential tool for intracellular transport of anticancer drugs. Nanoscale. 2011 Mar; 3(3):925-8. PMID: 21180768.
      Citations: 5     Fields:    Translation:HumansCells
    167. O'Neil CP, Reddy ST, Yu SS, Giorgio TD, Swartz MA, Hubbell JA, Thomas SN, van der Vlies AJ. Engineering complement activation on polypropylene sulfide vaccine nanoparticles. Biomaterials. 2011 Mar; 32(8):2194-203. PMID: 21183216.
      Citations: 46     Fields:    Translation:Animals
    168. Hasegawa U, O'Neil C, Angelova N, Hubbell JA, Wandrey C, van der Vlies AJ. Analytical ultracentrifugation to support the development of biomaterials and biomedical devices. Methods. 2011 May; 54(1):92-100. PMID: 21146611.
      Citations: 3     Fields:    
    169. Simeoni E, Wandrey C, Hubbell JA, Hasegawa U, van der Vlies AJ. Carbon monoxide-releasing micelles for immunotherapy. J Am Chem Soc. 2010 Dec 29; 132(51):18273-80. PMID: 21128648.
      Citations: 32     Fields:    Translation:Humans
    170. Martino MM, Swartz MA, Hubbell JA, Simeoni E, Stano A, van der Vlies AJ. PPS nanoparticles as versatile delivery system to induce systemic and broad mucosal immunity after intranasal administration. Vaccine. 2011 Jan 17; 29(4):804-12. PMID: 21094269.
      Citations: 22     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    171. Micol LA, Ananta M, Engelhardt EM, Mudera VC, Brown RA, Hubbell JA, Frey P. High-density collagen gel tubes as a matrix for primary human bladder smooth muscle cells. Biomaterials. 2011 Feb; 32(6):1543-8. PMID: 21074843.
      Citations: 14     Fields:    Translation:HumansCells
    172. Hubbell JA, Patterson J. SPARC-derived protease substrates to enhance the plasmin sensitivity of molecularly engineered PEG hydrogels. Biomaterials. 2011 Feb; 32(5):1301-10. PMID: 21040970.
      Citations: 38     Fields:    Translation:AnimalsCells
    173. Hubbell JA. Drug development: Longer-lived proteins. Nature. 2010 Oct 28; 467(7319):1051-2. PMID: 20981086.
      Citations: 2     Fields:    Translation:HumansAnimals
    174. Kraehenbuehl TP, Ferreira LS, Hayward AM, Nahrendorf M, Vasile E, Weissleder R, Langer R, Hubbell JA, van der Vlies AJ. Human embryonic stem cell-derived microvascular grafts for cardiac tissue preservation after myocardial infarction. Biomaterials. 2011 Feb; 32(4):1102-9. PMID: 21035182; PMCID: PMC6805145.
      Citations: 44     Fields:    Translation:HumansAnimalsCells
    175. Kourtis IC, Hubbell JA, Swartz MA, Hirosue S, van der Vlies AJ. Antigen delivery to dendritic cells by poly(propylene sulfide) nanoparticles with disulfide conjugated peptides: Cross-presentation and T cell activation. Vaccine. 2010 Nov 23; 28(50):7897-906. PMID: 20934457.
      Citations: 97     Fields:    Translation:AnimalsCells
    176. Angeloni S, Hubbell JA, Heinzelmann H, Popa AM, Bürgi T, Pugin R. Dynamic perspective on the function of thermoresponsive nanopores from in situ AFM and ATR-IR investigations. Langmuir. 2010 Oct 05; 26(19):15356-65. PMID: 20822117.
      Citations: 1     Fields:    
    177. Kontos S, Frey P, Hubbell JA, Lorentz KM. Engineered aprotinin for improved stability of fibrin biomaterials. Biomaterials. 2011 Jan; 32(2):430-8. PMID: 20864171.
      Citations: 32     Fields:    Translation:HumansAnimalsCells
    178. Hubbell JA, Kontos S. Improving protein pharmacokinetics by engineering erythrocyte affinity. Mol Pharm. 2010 Dec 06; 7(6):2141-7. PMID: 20831257.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    179. Bott K, Upton Z, Schrobback K, Ehrbar M, Hubbell JA, Lutolf MP, Rizzi SC. The effect of matrix characteristics on fibroblast proliferation in 3D gels. Biomaterials. 2010 Nov; 31(32):8454-64. PMID: 20684983.
      Citations: 105     Fields:    Translation:HumansCells
    180. Hubbell JA, Martino MM. The 12th-14th type III repeats of fibronectin function as a highly promiscuous growth factor-binding domain. FASEB J. 2010 Dec; 24(12):4711-21. PMID: 20671107.
      Citations: 151     Fields:    Translation:HumansCells
    181. Hubbell JA, Patterson J. Enhanced proteolytic degradation of molecularly engineered PEG hydrogels in response to MMP-1 and MMP-2. Biomaterials. 2010 Oct; 31(30):7836-45. PMID: 20667588.
      Citations: 239     Fields:    Translation:AnimalsCells
    182. Hubbell JA, Missirlis D. In vitro uptake of amphiphilic, hydrogel nanoparticles by J774A.1 cells. J Biomed Mater Res A. 2010 Jun 15; 93(4):1557-65. PMID: 20014289.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    183. Rizzi SC, Ehrbar M, Weber FE, Hubbell JA, Lutolf MP, Jo YS. Biomimetic PEG hydrogels crosslinked with minimal plasmin-sensitive tri-amino acid peptides. J Biomed Mater Res A. 2010 Jun 01; 93(3):870-7. PMID: 19701911.
      Citations: 17     Fields:    Translation:AnimalsCells
    184. Reddy ST, Velluto D, Colin P, Maillard A, Bensadoun JC, Hubbell JA, Renaud P, Mercanzini A. Controlled release nanoparticle-embedded coatings reduce the tissue reaction to neuroprostheses. J Control Release. 2010 Aug 03; 145(3):196-202. PMID: 20447428.
      Citations: 24     Fields:    Translation:Animals
    185. O'Neil CP, Hasegawa U, Hammond N, Hubbell JA, van der Vlies AJ. Synthesis of pyridyl disulfide-functionalized nanoparticles for conjugating thiol-containing small molecules, peptides, and proteins. Bioconjug Chem. 2010 Apr 21; 21(4):653-62. PMID: 20369815.
      Citations: 32     Fields:    Translation:Cells
    186. Ramseyer P, Micol LA, Engelhardt EM, Osterheld MC, Hubbell JA, Frey P. In vivo study of an injectable poly(acrylonitrile)-based hydrogel paste as a bulking agent for the treatment of urinary incontinence. Biomaterials. 2010 Jun; 31(17):4613-9. PMID: 20303170.
      Citations: 3     Fields:    Translation:Animals
    187. Vasdekis AE, O'Neil CP, Hubbell JA, Psaltis D. Microfluidic assays for DNA manipulation based on a block copolymer immobilization strategy. Biomacromolecules. 2010 Mar 08; 11(3):827-31. PMID: 20158193.
      Citations: 2     Fields:    Translation:Cells
    188. Stegberg E, Brown RA, Hubbell JA, Wurm FM, Adam M, Frey P, Engelhardt EM. Compressed collagen gel: a novel scaffold for human bladder cells. J Tissue Eng Regen Med. 2010 Feb; 4(2):123-30. PMID: 19842107.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    189. Pullin B, Hubbell JA, Klok HA, Lavanant L. A facile strategy for the modification of polyethylene substrates with non-fouling, bioactive poly(poly(ethylene glycol) methacrylate) brushes. Macromol Biosci. 2010 Jan 11; 10(1):101-8. PMID: 19890949.
      Citations: 4     Fields:    Translation:AnimalsCells
    190. Thomas SN, Swartz MA, Hubbell JA. Materials engineering for immunomodulation. Nature. 2009 Nov 26; 462(7272):449-60. PMID: 19940915.
      Citations: 187     Fields:    Translation:HumansAnimalsCells
    191. Yun JI, Jo YS, Mochizuki M, Kontos S, Ihm JE, Lim JM, Hubbell JA, Lee ST, van der Vlies AJ. Engineering integrin signaling for promoting embryonic stem cell self-renewal in a precisely defined niche. Biomaterials. 2010 Feb; 31(6):1219-26. PMID: 19926127.
      Citations: 60     Fields:    Translation:AnimalsCells
    192. Niedermann P, Heinzelmann H, Hubbell JA, Popa AM, Pugin R. Fabrication of nanopore arrays and ultrathin silicon nitride membranes by block-copolymer-assisted lithography. Nanotechnology. 2009 Dec 02; 20(48):485303. PMID: 19880976.
      Citations: 6     Fields:    
    193. Jo YS, Gantz J, Thacher TN, Antonijevic S, Cavadini S, Demurtas D, Stergiopulos N, Hubbell JA, van der Vlies AJ. Micelles for delivery of nitric oxide. J Am Chem Soc. 2009 Oct 14; 131(40):14413-8. PMID: 19764751.
      Citations: 17     Fields:    
    194. O'Neil CP, Velluto D, Fontana A, Adrian M, Dubochet J, Hubbell JA, Cerritelli S. Aggregation behavior of poly(ethylene glycol-bl-propylene sulfide) di- and triblock copolymers in aqueous solution. Langmuir. 2009 Oct 06; 25(19):11328-35. PMID: 19711914.
      Citations: 25     Fields:    Translation:Cells
    195. Suzuki T, Demurtas D, Finka A, Hubbell JA, O'Neil CP. A novel method for the encapsulation of biomolecules into polymersomes via direct hydration. Langmuir. 2009 Aug 18; 25(16):9025-9. PMID: 19621886.
      Citations: 21     Fields:    Translation:Animals
    196. Kraehenbuehl TP, Ferreira LS, Zammaretti P, Hubbell JA, Langer R. Cell-responsive hydrogel for encapsulation of vascular cells. Biomaterials. 2009 Sep; 30(26):4318-24. PMID: 19500842; PMCID: PMC4157733.
      Citations: 50     Fields:    Translation:HumansCells
    197. Hubbell JA, Rothenfluh DA. Integration column: biofunctional polymeric nanoparticles for spatio-temporal control of drug delivery and biomedical applications. Integr Biol (Camb). 2009 Jul; 1(7):446-51. PMID: 20023754.
      Citations: 5     Fields:    
    198. Bearinger JP, Stone G, Dugan LC, El Dasher B, Stockton C, Conway JW, Kuenzler T, Hubbell JA. Porphyrin-based photocatalytic nanolithography: a new fabrication tool for protein arrays. Mol Cell Proteomics. 2009 Aug; 8(8):1823-31. PMID: 19406753; PMCID: PMC2722779.
      Citations: 1     Fields:    Translation:Cells
    199. Velluto D, Wandrey C, Demurtas D, Dubochet J, Hubbell JA, O'Neil CP, van der Vlies AJ. Extracellular matrix binding mixed micelles for drug delivery applications. J Control Release. 2009 Jul 20; 137(2):146-51. PMID: 19332089.
      Citations: 11     Fields:    Translation:AnimalsCells
    200. Bearinger J, Dugan L, Wu L, Hill H, Christian A, Hubbell J. Chemical tethering of motile bacteria to silicon surfaces. Biotechniques. 2009 Mar; 46(3):209-16. PMID: 19317664; PMCID: PMC2693215.
      Citations: 7     Fields:    Translation:Cells
    201. Bearinger JP, Stone G, Hiddessen AL, Dugan LC, Wu L, Hailey P, Conway JW, Kuenzler T, Feller L, Cerritelli S, Hubbell JA. Phototocatalytic lithography of poly(propylene sulfide) block copolymers: toward high-throughput nanolithography for biomolecular arraying applications. Langmuir. 2009 Jan 20; 25(2):1238-44. PMID: 19113808; PMCID: PMC2663428.
      Citations: 1     Fields:    Translation:Cells
    202. Arrighi I, Mark S, Alvisi M, von Rechenberg B, Hubbell JA, Schense JC. Bone healing induced by local delivery of an engineered parathyroid hormone prodrug. Biomaterials. 2009 Mar; 30(9):1763-71. PMID: 19124152.
      Citations: 33     Fields:    Translation:HumansAnimals
    203. Mochizuki M, Rothenfluh DA, Rempel SA, Hubbell JA, Barker TH, Martino MM. Controlling integrin specificity and stem cell differentiation in 2D and 3D environments through regulation of fibronectin domain stability. Biomaterials. 2009 Feb; 30(6):1089-97. PMID: 19027948; PMCID: PMC2718049.
      Citations: 116     Fields:    Translation:HumansAnimalsCells
    204. Hubbell JA. Cellular matrices: Physiology in microfluidics. Nat Mater. 2008 Aug; 7(8):609-10. PMID: 18654581.
      Citations: 3     Fields:    Translation:Cells
    205. Feller L, Bearinger JP, Wu L, Hubbell JA, Textor M, Tosatti S. MICROPATTERNING OF GOLD SUBSTRATES BASED ON POLY(PROPYLENE SULFIDE-BL-ETHYLENE GLYCOL), (PPS-PEG) BACKGROUND PASSIVATION AND THE MOLECULAR-ASSEMBLY PATTERNING BY LIFT-OFF (MAPL) TECHNIQUE. Surf Sci. 2008 Jul 01; 602(13):2305-2310. PMID: 19578480; PMCID: PMC2610535.
      Citations: 1     
    206. Velluto D, Demurtas D, Hubbell JA. PEG-b-PPS diblock copolymer aggregates for hydrophobic drug solubilization and release: cyclosporin A as an example. Mol Pharm. 2008 Jul-Aug; 5(4):632-42. PMID: 18547055.
      Citations: 30     Fields:    Translation:Cells
    207. Zammaretti P, Schoenmakers RG, Lutolf MP, Jaconi ME, Hubbell JA, Kraehenbuehl TP, Van der Vlies AJ. Three-dimensional extracellular matrix-directed cardioprogenitor differentiation: systematic modulation of a synthetic cell-responsive PEG-hydrogel. Biomaterials. 2008 Jun; 29(18):2757-66. PMID: 18396331.
      Citations: 105     Fields:    Translation:AnimalsCells
    208. Bearinger JP, Stone G, Christian AT, Dugan L, Hiddessen AL, Wu KJ, Wu L, Hamilton J, Stockton C, Hubbell JA. Porphyrin-based photocatalytic lithography. Langmuir. 2008 May 06; 24(9):5179-84. PMID: 18380510; PMCID: PMC2515867.
      Citations: 5     Fields:    Translation:Cells
    209. Bermudez H, O'Neil CP, Hubbell JA, Rothenfluh DA. Biofunctional polymer nanoparticles for intra-articular targeting and retention in cartilage. Nat Mater. 2008 Mar; 7(3):248-54. PMID: 18246072.
      Citations: 132     Fields:    Translation:AnimalsCells
    210. Rehor A, Schmoekel H, Tirelli N, Hubbell JA. Functionalization of polysulfide nanoparticles and their performance as circulating carriers. Biomaterials. 2008 Apr; 29(12):1958-66. PMID: 18242691.
      Citations: 7     Fields:    Translation:AnimalsCells
    211. Hubbell JA, Reddy ST, Swartz MA. Lymphatic drainage function and its immunological implications: from dendritic cell homing to vaccine design. Semin Immunol. 2008 Apr; 20(2):147-56. PMID: 18201895.
      Citations: 54     Fields:    Translation:HumansAnimalsCells
    212. Steitz B, Finka A, O'Neil CP, Moniatte M, Giorgio TD, Hofmann H, Hubbell JA, Petri-Fink A, Salaklang J, van der Vlies AJ. Superparamagnetic nanoparticles as a powerful systems biology characterization tool in the physiological context. Angew Chem Int Ed Engl. 2008; 47(41):7857-60. PMID: 18792049.
      Citations: 4     Fields:    Translation:Cells
    213. Ehrbar M, Zeisberger SM, Raeber GP, Hubbell JA, Schnell C, Zisch AH. The role of actively released fibrin-conjugated VEGF for VEGF receptor 2 gene activation and the enhancement of angiogenesis. Biomaterials. 2008 Apr; 29(11):1720-9. PMID: 18155761.
      Citations: 49     Fields:    Translation:AnimalsCells
    214. Braschler T, Demierre N, Steitz B, Finka A, Hofmann H, Hubbell JA, Renaud P, Tornay R. Dielectrophoresis-based particle exchanger for the manipulation and surface functionalization of particles. Lab Chip. 2008 Feb; 8(2):267-73. PMID: 18231665.
      Citations: 12     Fields:    Translation:Cells
    215. Vilalta M, Matthies AM, Hubbell JA, Dimitriou H, Bianco P, Rubio N, Dégano IR, Bagó JR, Blanco J. Bioluminescence imaging of calvarial bone repair using bone marrow and adipose tissue-derived mesenchymal stem cells. Biomaterials. 2008 Feb; 29(4):427-37. PMID: 17950456.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    216. Segura T, Hubbell JA, Frey P, Adelöw C. The effect of enzymatically degradable poly(ethylene glycol) hydrogels on smooth muscle cell phenotype. Biomaterials. 2008 Jan; 29(3):314-26. PMID: 17953986.
      Citations: 34     Fields:    Translation:HumansCells
    217. Ehrbar M, Rizzi SC, Schoenmakers RG, Miguel BS, Hubbell JA, Weber FE, Lutolf MP. Biomolecular hydrogels formed and degraded via site-specific enzymatic reactions. Biomacromolecules. 2007 Oct; 8(10):3000-7. PMID: 17883273.
      Citations: 85     Fields:    Translation:HumansCells
    218. Simeoni E, Angeli V, Randolph GJ, O'Neil CP, Lee LK, Swartz MA, Hubbell JA, Reddy ST, van der Vlies AJ. Exploiting lymphatic transport and complement activation in nanoparticle vaccines. Nat Biotechnol. 2007 Oct; 25(10):1159-64. PMID: 17873867.
      Citations: 486     Fields:    Translation:AnimalsCells
    219. Raeber GP, Lutolf MP, Hubbell JA. Part II: Fibroblasts preferentially migrate in the direction of principal strain. Biomech Model Mechanobiol. 2008 Jun; 7(3):215-25. PMID: 17619206.
      Citations: 13     Fields:    Translation:HumansCells
    220. Lutolf MP, Hubbell JA, Raeber GP. Mechanisms of 3-D migration and matrix remodeling of fibroblasts within artificial ECMs. Acta Biomater. 2007 Sep; 3(5):615-29. PMID: 17572164.
      Citations: 36     Fields:    Translation:HumansCells
    221. Schmokel H, Hubbell JA, Segura T. RNA interference targeting hypoxia inducible factor 1alpha reduces post-operative adhesions in rats. J Surg Res. 2007 Aug; 141(2):162-70. PMID: 17561118.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    222. Velluto D, Hubbell JA, Cerritelli S. PEG-SS-PPS: reduction-sensitive disulfide block copolymer vesicles for intracellular drug delivery. Biomacromolecules. 2007 Jun; 8(6):1966-72. PMID: 17497921.
      Citations: 78     Fields:    Translation:AnimalsCells
    223. Mayer J, Hubbell JA, Raeber GP. Part I: A novel in-vitro system for simultaneous mechanical stimulation and time-lapse microscopy in 3D. Biomech Model Mechanobiol. 2008 Jun; 7(3):203-14. PMID: 17487518.
      Citations: 2     Fields:    Translation:HumansCells
    224. Walpoth BH, Zammaretti P, Cikirikcioglu M, Khabiri E, Djebaili MK, Pache JC, Tille JC, Aggoun Y, Morel D, Kalangos A, Hubbell JA, Zisch AH. Enhanced intimal thickening of expanded polytetrafluoroethylene grafts coated with fibrin or fibrin-releasing vascular endothelial growth factor in the pig carotid artery interposition model. J Thorac Cardiovasc Surg. 2007 May; 133(5):1163-70. PMID: 17467424.
      Citations: 15     Fields:    Translation:AnimalsCells
    225. Ehrbar M, Rizzi SC, Hlushchuk R, Djonov V, Zisch AH, Hubbell JA, Weber FE, Lutolf MP. Enzymatic formation of modular cell-instructive fibrin analogs for tissue engineering. Biomaterials. 2007 Sep; 28(26):3856-66. PMID: 17568666.
      Citations: 57     Fields:    Translation:HumansCells
    226. Hubbell JA, Segura T. Synthesis and in vitro characterization of an ABC triblock copolymer for siRNA delivery. Bioconjug Chem. 2007 May-Jun; 18(3):736-45. PMID: 17358044.
      Citations: 18     Fields:    Translation:HumansCells
    227. Hubbell JA. Matrix-bound growth factors in tissue repair. Swiss Med Wkly. 2007 Mar 02; 137 Suppl 155:72S-76S. PMID: 17874506.
      Citations: 1     Fields:    
    228. Vilalta M, Rodriguez J, Matthies AM, Srouji S, Livne E, Hubbell JA, Rubio N, Román I, Blanco J. Analysis of progenitor cell-scaffold combinations by in vivo non-invasive photonic imaging. Biomaterials. 2007 Jun; 28(17):2718-28. PMID: 17346789.
      Citations: 9     Fields:    Translation:AnimalsCells
    229. Reddy S, Velluto D, Colin P, Maillard A, Bensadoun JC, Bertsch A, Hubbell JA, Renaud P, Mercanzini A. Controlled release drug coatings on flexible neural probes. Annu Int Conf IEEE Eng Med Biol Soc. 2007; 2007:6613-6. PMID: 18003541.
      Citations: 1     Fields:    Translation:Animals
    230. Missirlis D, Hubbell JA, Tirelli N. Thermally-induced glass formation from hydrogel nanoparticles. Soft Matter. 2006 Nov 15; 2(12):1067-1075. PMID: 32680209.
      Citations: 3     Fields:    
    231. Rizzi SC, Ehrbar M, Halstenberg S, Raeber GP, Schmoekel HG, Weber FE, Hubbell JA, Hagenmüller H, Müller R. Recombinant protein-co-PEG networks as cell-adhesive and proteolytically degradable hydrogel matrixes. Part II: biofunctional characteristics. Biomacromolecules. 2006 Nov; 7(11):3019-29. PMID: 17096527.
      Citations: 52     Fields:    Translation:HumansAnimalsCells
    232. Swartz MA, Hubbell JA, Reddy ST. Targeting dendritic cells with biomaterials: developing the next generation of vaccines. Trends Immunol. 2006 Dec; 27(12):573-9. PMID: 17049307.
      Citations: 127     Fields:    Translation:HumansAnimalsCells
    233. Billinger M, Buddeberg F, Hubbell JA, Elbert DL, Schaffner T, Mettler D, Windecker S, Meier B, Hess OM. Polymer stent coating for prevention of neointimal hyperplasia. J Invasive Cardiol. 2006 Sep; 18(9):423-6; discussion 427. PMID: 16954581.
      Citations: 10     Fields:    Translation:Animals
    234. Kawamura R, Tirelli N, Hubbell JA, Missirlis D. Doxorubicin encapsulation and diffusional release from stable, polymeric, hydrogel nanoparticles. Eur J Pharm Sci. 2006 Oct 01; 29(2):120-9. PMID: 16904301.
      Citations: 42     Fields:    Translation:Cells
    235. Zihlmann P, Hubbell JA, Hall H, Reidy M. Activation of cell-survival transcription factor NFkappaB in L1Ig6-stimulated endothelial cells. J Biomed Mater Res A. 2006 Jun 01; 77(3):542-50. PMID: 16493660.
      Citations: 4     Fields:    Translation:HumansCells
    236. Hubbell JA. Non-viral gene delivery: multifunctional polyplexes as locally triggerable nonviral vectors. Gene Ther. 2006 Oct; 13(19):1371-2. PMID: 16541118.
      Citations: 1     Fields:    Translation:HumansAnimals
    237. Rehor A, Schmoekel HG, Hubbell JA, Swartz MA, Reddy ST. In vivo targeting of dendritic cells in lymph nodes with poly(propylene sulfide) nanoparticles. J Control Release. 2006 May 01; 112(1):26-34. PMID: 16529839.
      Citations: 250     Fields:    Translation:AnimalsCells
    238. Hall H, Wechsler S, Hubbell JA, Trentin D. Peptide-matrix-mediated gene transfer of an oxygen-insensitive hypoxia-inducible factor-1alpha variant for local induction of angiogenesis. Proc Natl Acad Sci U S A. 2006 Feb 21; 103(8):2506-11. PMID: 16477043; PMCID: PMC1413769.
      Citations: 43     Fields:    Translation:HumansAnimalsCells
    239. Lussi JW, Falconnet D, Hubbell JA, Textor M, Csucs G. Pattern stability under cell culture conditions--a comparative study of patterning methods based on PLL-g-PEG background passivation. Biomaterials. 2006 Apr; 27(12):2534-41. PMID: 16364431.
      Citations: 15     Fields:    Translation:AnimalsCells
    240. Karrer L, Duwe J, Zisch AH, Khabiri E, Cikirikcioglu M, Napoli A, Goessl A, Schaffner T, Hess OM, Carrel T, Kalangos A, Hubbell JA, Walpoth BH. PPS-PEG surface coating to reduce thrombogenicity of small diameter ePTFE vascular grafts. Int J Artif Organs. 2005 Oct; 28(10):993-1002. PMID: 16288437.
      Citations:    Fields:    Translation:Animals
    241. Napoli A, Bermudez H, Hubbell JA. Interfacial reactivity of block copolymers: understanding the amphiphile-to-hydrophile transition. Langmuir. 2005 Sep 27; 21(20):9149-53. PMID: 16171345.
      Citations: 5     Fields:    Translation:Cells
    242. Tae G, Kornfield JA, Hubbell JA. Sustained release of human growth hormone from in situ forming hydrogels using self-assembly of fluoroalkyl-ended poly(ethylene glycol). Biomaterials. 2005 Sep; 26(25):5259-66. PMID: 15792553.
      Citations: 17     Fields:    Translation:HumansCells
    243. Maynard HD, Hubbell JA. Discovery of a sulfated tetrapeptide that binds to vascular endothelial growth factor. Acta Biomater. 2005 Jul; 1(4):451-9. PMID: 16701826.
      Citations: 22     Fields:    Translation:Cells
    244. Lutolf MP, Hubbell JA, Raeber GP. Molecularly engineered PEG hydrogels: a novel model system for proteolytically mediated cell migration. Biophys J. 2005 Aug; 89(2):1374-88. PMID: 15923238; PMCID: PMC1366622.
      Citations: 201     Fields:    Translation:HumansCells
    245. Meinhart JG, Schense JC, Schima H, Gorlitzer M, Hubbell JA, Deutsch M, Zilla P. Enhanced endothelial cell retention on shear-stressed synthetic vascular grafts precoated with RGD-cross-linked fibrin. Tissue Eng. 2005 May-Jun; 11(5-6):887-95. PMID: 15998228.
      Citations: 15     Fields:    Translation:HumansCells
    246. Hubbell JA, Rizzi SC. Recombinant protein-co-PEG networks as cell-adhesive and proteolytically degradable hydrogel matrixes. Part I: Development and physicochemical characteristics. Biomacromolecules. 2005 May-Jun; 6(3):1226-38. PMID: 15877337.
      Citations: 42     Fields:    Translation:Cells
    247. Raeber G, Sennhauser U, Hubbell JA, Thurner P, Müller R. 3D morphology of cell cultures: a quantitative approach using micrometer synchrotron light tomography. Microsc Res Tech. 2005 Apr 15; 66(6):289-98. PMID: 16003782.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    248. Urech L, Bittermann AG, Hubbell JA, Hall H. Mechanical properties, proteolytic degradability and biological modifications affect angiogenic process extension into native and modified fibrin matrices in vitro. Biomaterials. 2005 Apr; 26(12):1369-79. PMID: 15482824.
      Citations: 24     Fields:    Translation:HumansCells
    249. Sauthier F, Hubbell JA, Hall H, Pittier R. Neurite extension and in vitro myelination within three-dimensional modified fibrin matrices. J Neurobiol. 2005 Apr; 63(1):1-14. PMID: 15616962.
      Citations: 24     Fields:    Translation:HumansAnimalsCells
    250. Weber CC, Cai H, Ehrbar M, Kubota H, Martiny-Baron G, Weber W, Djonov V, Weber E, Mallik AS, Fussenegger M, Frei K, Hubbell JA, Zisch AH. Effects of protein and gene transfer of the angiopoietin-1 fibrinogen-like receptor-binding domain on endothelial and vessel organization. J Biol Chem. 2005 Jun 10; 280(23):22445-53. PMID: 15781448.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    251. Missirlis D, Tirelli N, Hubbell JA. Amphiphilic hydrogel nanoparticles. Preparation, characterization, and preliminary assessment as new colloidal drug carriers. Langmuir. 2005 Mar 15; 21(6):2605-13. PMID: 15752059.
      Citations: 12     Fields:    
    252. van de Wetering P, Metters AT, Schoenmakers RG, Hubbell JA. Poly(ethylene glycol) hydrogels formed by conjugate addition with controllable swelling, degradation, and release of pharmaceutically active proteins. J Control Release. 2005 Feb 16; 102(3):619-27. PMID: 15681084.
      Citations: 47     Fields:    Translation:Humans
    253. Schmoekel HG, Weber FE, Schense JC, Schawalder P, Hubbell JA, Grätz KW. Bone repair with a form of BMP-2 engineered for incorporation into fibrin cell ingrowth matrices. Biotechnol Bioeng. 2005 Feb 05; 89(3):253-62. PMID: 15619323.
      Citations: 50     Fields:    Translation:AnimalsCells
    254. Ihm JE, Han KO, Hwang CS, Kang JH, Ahn KD, Han IK, Han DK, Hubbell JA, Cho CS. Poly (4-vinylimidazole) as nonviral gene carrier: in vitro and in vivo transfection. Acta Biomater. 2005 Mar; 1(2):165-72. PMID: 16701793.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    255. Trentin D, Hubbell J, Hall H. Non-viral gene delivery for local and controlled DNA release. J Control Release. 2005 Jan 20; 102(1):263-75. PMID: 15653151.
      Citations: 29     Fields:    Translation:HumansAnimalsCells
    256. Rehor A, Hubbell JA, Tirelli N. Oxidation-sensitive polymeric nanoparticles. Langmuir. 2005 Jan 04; 21(1):411-7. PMID: 15620332.
      Citations: 26     Fields:    
    257. Ehrbar M, Metters A, Zammaretti P, Hubbell JA, Zisch AH. Endothelial cell proliferation and progenitor maturation by fibrin-bound VEGF variants with differential susceptibilities to local cellular activity. J Control Release. 2005 Jan 03; 101(1-3):93-109. PMID: 15588897.
      Citations: 45     Fields:    Translation:HumansCells
    258. Fittkau MH, Zilla P, Bezuidenhout D, Lutolf MP, Human P, Hubbell JA, Davies N. The selective modulation of endothelial cell mobility on RGD peptide containing surfaces by YIGSR peptides. Biomaterials. 2005 Jan; 26(2):167-74. PMID: 15207463.
      Citations: 45     Fields:    Translation:HumansCells
    259. Metters A, Hubbell J. Network formation and degradation behavior of hydrogels formed by Michael-type addition reactions. Biomacromolecules. 2005 Jan-Feb; 6(1):290-301. PMID: 15638532.
      Citations: 90     Fields:    
    260. Schmoekel HG, Weber FE, Hurter K, Schense JC, Seiler G, Ryrz U, Spreng D, Schawalder P, Hubbell J. Enhancement of bone healing using non-glycosylated rhBMP-2 released from a fibrin matrix in dogs and cats. J Small Anim Pract. 2005 Jan; 46(1):17-21. PMID: 15682735.
      Citations: 7     Fields:    Translation:Animals
    261. Hubbell JA, Lutolf MP. Synthetic biomaterials as instructive extracellular microenvironments for morphogenesis in tissue engineering. Nat Biotechnol. 2005 Jan; 23(1):47-55. PMID: 15637621.
      Citations: 1184     Fields:    Translation:HumansAnimalsCells
    262. Cellesi F, Weber W, Fussenegger M, Hubbell JA, Tirelli N. Towards a fully synthetic substitute of alginate: optimization of a thermal gelation/chemical cross-linking scheme ("tandem" gelation) for the production of beads and liquid-core capsules. Biotechnol Bioeng. 2004 Dec 20; 88(6):740-9. PMID: 15532084.
      Citations: 6     Fields:    Translation:AnimalsCells
    263. Hall H, Hubbell JA. Matrix-bound sixth Ig-like domain of cell adhesion molecule L1 acts as an angiogenic factor by ligating alphavbeta3-integrin and activating VEGF-R2. Microvasc Res. 2004 Nov; 68(3):169-78. PMID: 15501236.
      Citations: 13     Fields:    Translation:AnimalsCells
    264. Hubbell JA. Tissue and cell engineering. Curr Opin Biotechnol. 2004 Oct; 15(5):381-2. PMID: 15464365.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    265. Cellesi F, Tirelli N, Hubbell JA. Towards a fully-synthetic substitute of alginate: development of a new process using thermal gelation and chemical cross-linking. Biomaterials. 2004 Sep; 25(21):5115-24. PMID: 15109835.
      Citations: 19     Fields:    Translation:HumansCells
    266. Zisch AH, Zeisberger SM, Ehrbar M, Djonov V, Weber CC, Ziemiecki A, Pasquale EB, Hubbell JA. Engineered fibrin matrices for functional display of cell membrane-bound growth factor-like activities: study of angiogenic signaling by ephrin-B2. Biomaterials. 2004 Jul; 25(16):3245-57. PMID: 14980419.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    267. Hubbell JA. Biomaterials science and high-throughput screening. Nat Biotechnol. 2004 Jul; 22(7):828-9. PMID: 15229544.
      Citations: 9     Fields:    Translation:Cells
    268. Napoli A, Boerakker MJ, Tirelli N, Nolte RJ, Sommerdijk NA, Hubbell JA. Glucose-oxidase based self-destructing polymeric vesicles. Langmuir. 2004 Apr 27; 20(9):3487-91. PMID: 15875368.
      Citations: 26     Fields:    Translation:Cells
    269. Pratt AB, Weber FE, Schmoekel HG, Hubbell JA, Müller R. Synthetic extracellular matrices for in situ tissue engineering. Biotechnol Bioeng. 2004 Apr 05; 86(1):27-36. PMID: 15007838.
      Citations: 48     Fields:    Translation:HumansAnimalsCells
    270. Ehrbar M, Djonov VG, Schnell C, Tschanz SA, Martiny-Baron G, Schenk U, Wood J, Burri PH, Hubbell JA, Zisch AH. Cell-demanded liberation of VEGF121 from fibrin implants induces local and controlled blood vessel growth. Circ Res. 2004 Apr 30; 94(8):1124-32. PMID: 15044320.
      Citations: 99     Fields:    Translation:HumansAnimalsCells
    271. Seliktar D, Zisch AH, Lutolf MP, Wrana JL, Hubbell JA. MMP-2 sensitive, VEGF-bearing bioactive hydrogels for promotion of vascular healing. J Biomed Mater Res A. 2004 Mar 15; 68(4):704-16. PMID: 14986325.
      Citations: 89     Fields:    Translation:HumansCells
    272. Schoenmakers RG, van de Wetering P, Elbert DL, Hubbell JA. The effect of the linker on the hydrolysis rate of drug-linked ester bonds. J Control Release. 2004 Mar 05; 95(2):291-300. PMID: 14980777.
      Citations: 34     Fields:    Translation:Cells
    273. Weber FE, Seiler G, von Rechenberg B, Schense JC, Schawalder P, Hubbell J, Schmökel HG. Treatment of nonunions with nonglycosylated recombinant human bone morphogenetic protein-2 delivered from a fibrin matrix. Vet Surg. 2004 Mar-Apr; 33(2):112-8. PMID: 15027972.
      Citations: 5     Fields:    Translation:Animals
    274. Schmoekel H, Schense JC, Weber FE, Hubbell JA, Grätz KW, Gnägi D, Müller R. Bone healing in the rat and dog with nonglycosylated BMP-2 demonstrating low solubility in fibrin matrices. J Orthop Res. 2004 Mar; 22(2):376-81. PMID: 15013099.
      Citations: 18     Fields:    Translation:AnimalsCellsCTClinical Trials
    275. Schwartz Z, Campbell C, Cochran DL, VandeVondele S, Hubbell JA, Denzer A, Simpson J, Wieland M, Lohmann CH, Textor M, Boyan BD, Tosatti S. RGD-containing peptide GCRGYGRGDSPG reduces enhancement of osteoblast differentiation by poly(L-lysine)-graft-poly(ethylene glycol)-coated titanium surfaces. J Biomed Mater Res A. 2004 Mar 01; 68(3):458-72. PMID: 14762925.
      Citations: 21     Fields:    Translation:HumansCells
    276. Park Y, Lutolf MP, Hubbell JA, Hunziker EB, Wong M. Bovine primary chondrocyte culture in synthetic matrix metalloproteinase-sensitive poly(ethylene glycol)-based hydrogels as a scaffold for cartilage repair. Tissue Eng. 2004 Mar-Apr; 10(3-4):515-22. PMID: 15165468.
      Citations: 65     Fields:    Translation:AnimalsCells
    277. Valentini M, Vaccaro A, Rehor A, Napoli A, Hubbell JA, Tirelli N. Diffusion NMR spectroscopy for the characterization of the size and interactions of colloidal matter: the case of vesicles and nanoparticles. J Am Chem Soc. 2004 Feb 25; 126(7):2142-7. PMID: 14971949.
      Citations: 9     Fields:    Translation:Cells
    278. Napoli A, Valentini M, Tirelli N, Hubbell JA, Müller M. Oxidation-responsive polymeric vesicles. Nat Mater. 2004 Mar; 3(3):183-9. PMID: 14991021.
      Citations: 165     Fields:    Translation:Cells
    279. Kim DH, Haake A, Sun Y, Neild AP, Ihm JE, Dual J, Hubbell JA, Ju BK, Nelson BJ. High-throughput cell manipulation using ultrasound fields. Conf Proc IEEE Eng Med Biol Soc. 2004; 2004:2571-4. PMID: 17270799.
      Citations: 2     Fields:    
    280. Hall H, Djonov V, Ehrbar M, Hoechli M, Hubbell JA. Heterophilic interactions between cell adhesion molecule L1 and alphavbeta3-integrin induce HUVEC process extension in vitro and angiogenesis in vivo. Angiogenesis. 2004; 7(3):213-23. PMID: 15609076.
      Citations: 6     Fields:    Translation:HumansCells
    281. Goessl A, Tirelli N, Hubbell JA. A hydrogel system for stimulus-responsive, oxygen-sensitive in situ gelation. J Biomater Sci Polym Ed. 2004; 15(7):895-904. PMID: 15318799.
      Citations: 6     Fields:    Translation:Cells
    282. Hall H, Bozic D, Michel K, Hubbell JA. N-terminal alpha-dystroglycan binds to different extracellular matrix molecules expressed in regenerating peripheral nerves in a protein-mediated manner and promotes neurite extension of PC12 cells. Mol Cell Neurosci. 2003 Dec; 24(4):1062-73. PMID: 14697669.
      Citations: 9     Fields:    Translation:AnimalsCells
    283. Tosatti S, De Paul SM, Askendal A, VandeVondele S, Hubbell JA, Tengvall P, Textor M. Peptide functionalized poly(L-lysine)-g-poly(ethylene glycol) on titanium: resistance to protein adsorption in full heparinized human blood plasma. Biomaterials. 2003 Dec; 24(27):4949-58. PMID: 14559008.
      Citations: 23     Fields:    Translation:Humans
    284. Zisch AH, Lutolf MP, Hubbell JA. Biopolymeric delivery matrices for angiogenic growth factors. Cardiovasc Pathol. 2003 Nov-Dec; 12(6):295-310. PMID: 14630296.
      Citations: 92     Fields:    Translation:Humans
    285. Zisch AH, Lutolf MP, Ehrbar M, Raeber GP, Rizzi SC, Davies N, Bezuidenhout D, Djonov V, Zilla P, Hubbell JA, Schmökel H. Cell-demanded release of VEGF from synthetic, biointeractive cell ingrowth matrices for vascularized tissue growth. FASEB J. 2003 Dec; 17(15):2260-2. PMID: 14563693.
      Citations: 162     Fields:    Translation:Animals
    286. Hubbell JA. Tissue and cell engineering. Curr Opin Biotechnol. 2003 Oct; 14(5):517-9. PMID: 14580582.
      Citations: 1     Fields:    
    287. Hubbell JA. Materials as morphogenetic guides in tissue engineering. Curr Opin Biotechnol. 2003 Oct; 14(5):551-8. PMID: 14580588.
      Citations: 71     Fields:    Translation:HumansAnimalsCells
    288. Kusonwiriyawong C, van de Wetering P, Hubbell JA, Merkle HP, Walter E. Evaluation of pH-dependent membrane-disruptive properties of poly(acrylic acid) derived polymers. Eur J Pharm Biopharm. 2003 Sep; 56(2):237-46. PMID: 12957638.
      Citations: 19     Fields:    Translation:HumansCells
    289. Heggli M, Tirelli N, Zisch A, Hubbell JA. Michael-type addition as a tool for surface functionalization. Bioconjug Chem. 2003 Sep-Oct; 14(5):967-73. PMID: 13129400.
      Citations: 8     Fields:    
    290. VandeVondele S, Hubbell JA, Vörös J. RGD-grafted poly-L-lysine-graft-(polyethylene glycol) copolymers block non-specific protein adsorption while promoting cell adhesion. Biotechnol Bioeng. 2003 Jun 30; 82(7):784-90. PMID: 12701144.
      Citations: 63     Fields:    Translation:HumansCells
    291. Hubbell JA, Textor M, Bearinger JP, Vörös J. Electrochemical optical waveguide lightmode spectroscopy (EC-OWLS): a pilot study using evanescent-field optical sensing under voltage control to monitor polycationic polymer adsorption onto indium tin oxide (ITO)-coated waveguide chips. Biotechnol Bioeng. 2003 May 20; 82(4):465-73. PMID: 12632403.
      Citations: 10     Fields:    Translation:Cells
    292. Lutolf MP, Hubbell JA. Synthesis and physicochemical characterization of end-linked poly(ethylene glycol)-co-peptide hydrogels formed by Michael-type addition. Biomacromolecules. 2003 May-Jun; 4(3):713-22. PMID: 12741789.
      Citations: 179     Fields:    
    293. Hubbell JA. Materials science. Enhancing drug function. Science. 2003 Apr 25; 300(5619):595-6. PMID: 12714733.
      Citations: 26     Fields:    Translation:Cells
    294. Lutolf MP, Weber FE, Schmoekel HG, Schense JC, Kohler T, Hubbell JA, Müller R. Repair of bone defects using synthetic mimetics of collagenous extracellular matrices. Nat Biotechnol. 2003 May; 21(5):513-8. PMID: 12704396.
      Citations: 200     Fields:    Translation:AnimalsCells
    295. Lutolf MP, Lauer-Fields JL, Schmoekel HG, Metters AT, Weber FE, Fields GB, Hubbell JA. Synthetic matrix metalloproteinase-sensitive hydrogels for the conduction of tissue regeneration: engineering cell-invasion characteristics. Proc Natl Acad Sci U S A. 2003 Apr 29; 100(9):5413-8. PMID: 12686696; PMCID: PMC154359.
      Citations: 470     Fields:    Translation:HumansAnimalsCells
    296. Bearinger JP, Terrettaz S, Michel R, Tirelli N, Vogel H, Textor M, Hubbell JA. Chemisorbed poly(propylene sulphide)-based copolymers resist biomolecular interactions. Nat Mater. 2003 Apr; 2(4):259-64. PMID: 12690400.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    297. Vernon B, Tirelli N, Haldimann D, Hubbell JA, Bächi T. Water-borne, in situ crosslinked biomaterials from phase-segregated precursors. J Biomed Mater Res A. 2003 Mar 01; 64(3):447-56. PMID: 12579558.
      Citations: 11     Fields:    Translation:Cells
    298. Tirelli N, Hubbell JA, Park YD. Photopolymerized hyaluronic acid-based hydrogels and interpenetrating networks. Biomaterials. 2003 Mar; 24(6):893-900. PMID: 12504509.
      Citations: 87     Fields:    Translation:HumansCells
    299. Halstenberg S, Panitch A, Rizzi S, Hall H, Hubbell JA. Biologically engineered protein-graft-poly(ethylene glycol) hydrogels: a cell adhesive and plasmin-degradable biosynthetic material for tissue repair. Biomacromolecules. 2002 Jul-Aug; 3(4):710-23. PMID: 12099815.
      Citations: 55     Fields:    Translation:HumansCells
    300. Winblade ND, Baumann M, Hoffman AS, Hubbell JA, Schmökel H. Sterically blocking adhesion of cells to biological surfaces with a surface-active copolymer containing poly(ethylene glycol) and phenylboronic acid. J Biomed Mater Res. 2002 Mar 15; 59(4):618-31. PMID: 11774323.
      Citations: 10     Fields:    
    301. Tirelli N, Lutolf MP, Napoli A, Hubbell JA. Poly(ethylene glycol) block copolymers. J Biotechnol. 2002 Mar; 90(1):3-15. PMID: 12069046.
      Citations: 8     Fields:    Translation:Cells
    302. Lutolf MP, Tirelli N, Cerritelli S, Cavalli L, Hubbell JA. Systematic modulation of Michael-type reactivity of thiols through the use of charged amino acids. Bioconjug Chem. 2001 Nov-Dec; 12(6):1051-6. PMID: 11716699.
      Citations: 86     Fields:    
    303. Hall H, Baechi T, Hubbell JA. Molecular properties of fibrin-based matrices for promotion of angiogenesis in vitro. Microvasc Res. 2001 Nov; 62(3):315-26. PMID: 11678634.
      Citations: 14     Fields:    Translation:HumansCells
    304. Elbert DL, Pratt AB, Lutolf MP, Halstenberg S, Hubbell JA. Protein delivery from materials formed by self-selective conjugate addition reactions. J Control Release. 2001 Sep 11; 76(1-2):11-25. PMID: 11532309.
      Citations: 62     Fields:    
    305. Zisch AH, Schenk U, Schense JC, Sakiyama-Elbert SE, Hubbell JA. Covalently conjugated VEGF--fibrin matrices for endothelialization. J Control Release. 2001 May 14; 72(1-3):101-13. PMID: 11389989.
      Citations: 89     Fields:    Translation:Humans
    306. Sakiyama-Elbert SE, Panitch A, Hubbell JA. Development of growth factor fusion proteins for cell-triggered drug delivery. FASEB J. 2001 May; 15(7):1300-2. PMID: 11344120.
      Citations: 39     Fields:    Translation:HumansAnimalsCells
    307. Kao WJ, Lee D, Schense JC, Hubbell JA. Fibronectin modulates macrophage adhesion and FBGC formation: the role of RGD, PHSRN, and PRRARV domains. J Biomed Mater Res. 2001 Apr; 55(1):79-88. PMID: 11426401.
      Citations: 29     Fields:    Translation:HumansCells
    308. Elbert DL, Hubbell JA. Conjugate addition reactions combined with free-radical cross-linking for the design of materials for tissue engineering. Biomacromolecules. 2001; 2(2):430-41. PMID: 11749203.
      Citations: 90     Fields:    Translation:HumansCells
    309. Sakiyama-Elbert SE, Hubbell JA. Controlled release of nerve growth factor from a heparin-containing fibrin-based cell ingrowth matrix. J Control Release. 2000 Oct 03; 69(1):149-58. PMID: 11018553.
      Citations: 106     Fields:    
    310. Benedikt P, Jockenhoevel S, Hoerstrup SP, Sakyama S, Hubbell JA, Turina M, Ye Q, Zünd G. Fibrin gel as a three dimensional matrix in cardiovascular tissue engineering. Eur J Cardiothorac Surg. 2000 May; 17(5):587-91. PMID: 10814924.
      Citations: 80     Fields:    Translation:HumansCells
    311. Sakiyama-Elbert SE, Hubbell JA. Development of fibrin derivatives for controlled release of heparin-binding growth factors. J Control Release. 2000 Apr 03; 65(3):389-402. PMID: 10699297.
      Citations: 136     Fields:    Translation:AnimalsCells
    312. Schense JC, Bloch J, Aebischer P, Hubbell JA. Enzymatic incorporation of bioactive peptides into fibrin matrices enhances neurite extension. Nat Biotechnol. 2000 Apr; 18(4):415-9. PMID: 10748522.
      Citations: 57     Fields:    Translation:AnimalsCells
    313. Schense JC, Hubbell JA. Three-dimensional migration of neurites is mediated by adhesion site density and affinity. J Biol Chem. 2000 Mar 10; 275(10):6813-8. PMID: 10702239.
      Citations: 34     Fields:    Translation:AnimalsCells
    314. An Y, Hubbell JA. Intraarterial protein delivery via intimally-adherent bilayer hydrogels. J Control Release. 2000 Feb 14; 64(1-3):205-15. PMID: 10640658.
      Citations: 16     Fields:    Translation:Animals
    315. Winblade ND, Nikolic ID, Hoffman AS, Hubbell JA. Blocking adhesion to cell and tissue surfaces by the chemisorption of a poly-L-lysine-graft-(poly(ethylene glycol); phenylboronic acid) copolymer. Biomacromolecules. 2000; 1(4):523-33. PMID: 11710177.
      Citations: 10     Fields:    Translation:Cells
    316. Barnhart MD, Hubbell JA, Muir WW, Sams RA, Bednarski RM. Pharmacokinetics, pharmacodynamics, and analgesic effects of morphine after rectal, intramuscular, and intravenous administration in dogs. Am J Vet Res. 2000 Jan; 61(1):24-8. PMID: 10630773.
      Citations: 7     Fields:    Translation:Animals
    317. Sakiyama SE, Schense JC, Hubbell JA. Incorporation of heparin-binding peptides into fibrin gels enhances neurite extension: an example of designer matrices in tissue engineering. FASEB J. 1999 Dec; 13(15):2214-24. PMID: 10593869.
      Citations: 44     Fields:    Translation:HumansAnimalsCells
    318. Hegre OD, Lamberti FV, Hager SR, Hill R, Scharp DS, Hubbell JA, Cruise GM. In vitro and in vivo performance of porcine islets encapsulated in interfacially photopolymerized poly(ethylene glycol) diacrylate membranes. Cell Transplant. 1999 May-Jun; 8(3):293-306. PMID: 10442742.
      Citations: 66     Fields:    Translation:Animals
    319. Hubbell JA. Bioactive biomaterials. Curr Opin Biotechnol. 1999 Apr; 10(2):123-9. PMID: 10209141.
      Citations: 75     Fields:    
    320. Lore AB, Hubbell JA, Bobb DS, Ballinger ML, Loftin KL, Smith JW, Smyers ME, Garcia HD, Bittner GD. Rapid induction of functional and morphological continuity between severed ends of mammalian or earthworm myelinated axons. J Neurosci. 1999 Apr 01; 19(7):2442-54. PMID: 10087059; PMCID: PMC6786066.
      Citations: 26     Fields:    Translation:AnimalsCells
    321. Hubbell JA. Biotechnology. A new-for-old urinary bladder. Nature. 1999 Mar 18; 398(6724):198-9. PMID: 10094041.
      Citations:    Fields:    Translation:Animals
    322. Sawhney AS, Hubbell JA. In situ photopolymerized hydrogels for vascular and peritoneal wound healing. Methods Mol Med. 1999; 18:85-100. PMID: 21370170.
      Citations:    Fields:    
    323. Schense JC, Hubbell JA. Cross-linking exogenous bifunctional peptides into fibrin gels with factor XIIIa. Bioconjug Chem. 1999 Jan-Feb; 10(1):75-81. PMID: 9893967.
      Citations: 58     Fields:    Translation:AnimalsCells
    324. Elbert DL, Hubbell JA. Reduction of fibrous adhesion formation by a copolymer possessing an affinity for anionic surfaces. J Biomed Mater Res. 1998 Oct; 42(1):55-65. PMID: 9740007.
      Citations: 10     Fields:    Translation:AnimalsCells
    325. Kao WJ, Hubbell JA. Murine macrophage behavior on peptide-grafted polyethyleneglycol-containing networks. Biotechnol Bioeng. 1998 Jul 05; 59(1):2-9. PMID: 10099308.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    326. Cruise GM, Scharp DS, Hubbell JA. Characterization of permeability and network structure of interfacially photopolymerized poly(ethylene glycol) diacrylate hydrogels. Biomaterials. 1998 Jul; 19(14):1287-94. PMID: 9720892.
      Citations: 164     Fields:    
    327. Herbert CB, Nagaswami C, Bittner GD, Hubbell JA, Weisel JW. Effects of fibrin micromorphology on neurite growth from dorsal root ganglia cultured in three-dimensional fibrin gels. J Biomed Mater Res. 1998 Jun 15; 40(4):551-9. PMID: 9599031.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    328. Cruise GM, Hegre OD, Scharp DS, Hubbell JA. A sensitivity study of the key parameters in the interfacial photopolymerization of poly(ethylene glycol) diacrylate upon porcine islets. Biotechnol Bioeng. 1998 Mar 20; 57(6):655-65. PMID: 10099245.
      Citations: 67     Fields:    Translation:Animals
    329. Elbert DL, Hubbell JA. Self-assembly and steric stabilization at heterogeneous, biological surfaces using adsorbing block copolymers. Chem Biol. 1998 Mar; 5(3):177-83. PMID: 9545428.
      Citations: 24     Fields:    Translation:HumansAnimalsCells
    330. Hern DL, Hubbell JA. Incorporation of adhesion peptides into nonadhesive hydrogels useful for tissue resurfacing. J Biomed Mater Res. 1998 Feb; 39(2):266-76. PMID: 9457557.
      Citations: 203     Fields:    Translation:HumansCells
    331. Noh I, Goodman SL, Hubbell JA. Chemical modification and photograft polymerization upon expanded poly(tetrafluoroethylene). J Biomater Sci Polym Ed. 1998; 9(5):407-26. PMID: 9648024.
      Citations: 4     Fields:    
    332. Han DK, Park KD, Hubbell JA, Kim YH. Surface characteristics and biocompatibility of lactide-based poly(ethylene glycol) scaffolds for tissue engineering. J Biomater Sci Polym Ed. 1998; 9(7):667-80. PMID: 9686334.
      Citations: 11     Fields:    Translation:HumansCells
    333. Hill RS, Cruise GM, Hager SR, Lamberti FV, Yu X, Garufis CL, Yu Y, Mundwiler KE, Cole JF, Hubbell JA, Hegre OD, Scharp DW. Immunoisolation of adult porcine islets for the treatment of diabetes mellitus. The use of photopolymerizable polyethylene glycol in the conformal coating of mass-isolated porcine islets. Ann N Y Acad Sci. 1997 Dec 31; 831:332-43. PMID: 9616725.
      Citations: 25     Fields:    Translation:Animals
    334. West JL, Hubbell JA. Separation of the arterial wall from blood contact using hydrogel barriers reduces intimal thickening after balloon injury in the rat: the roles of medial and luminal factors in arterial healing. Proc Natl Acad Sci U S A. 1996 Nov 12; 93(23):13188-93. PMID: 8917566; PMCID: PMC24068.
      Citations: 17     Fields:    Translation:AnimalsPHPublic Health
    335. Herbert CB, Hernandez AM, Hubbell JA. Platelet adhesion to polyurethane blended with polytetramethylene oxide. Biotechnol Bioeng. 1996 Oct 05; 52(1):81-8. PMID: 18629853.
      Citations:    Fields:    
    336. West JL, Chowdhury SM, Sawhney AS, Pathak CP, Dunn RC, Hubbell JA. Efficacy of adhesion barriers. Resorbable hydrogel, oxidized regenerated cellulose and hyaluronic acid. J Reprod Med. 1996 Mar; 41(3):149-54. PMID: 8778411.
      Citations: 2     Fields:    Translation:AnimalsPHPublic Health
    337. Chowdhury SM, Hubbell JA. Adhesion prevention with ancrod released via a tissue-adherent hydrogel. J Surg Res. 1996 Feb 15; 61(1):58-64. PMID: 8769943.
      Citations: 8     Fields:    Translation:Animals
    338. Herbert CB, Bittner GD, Hubbell JA. Effects of fibinolysis on neurite growth from dorsal root ganglia cultured in two- and three-dimensional fibrin gels. J Comp Neurol. 1996 Feb 12; 365(3):380-91. PMID: 8822177.
      Citations: 15     Fields:    Translation:AnimalsCells
    339. Frautschi JR, Eberhart RC, Hubbell JA, Clark BD, Gelfand JA. Alkylation of cellulosic membranes results in reduced complement activation. J Biomater Sci Polym Ed. 1996; 7(8):707-14. PMID: 8639479.
      Citations:    Fields:    Translation:HumansCells
    340. Hill-West JL, Dunn RC, Hubbell JA. Local release of fibrinolytic agents for adhesion prevention. J Surg Res. 1995 Dec; 59(6):759-63. PMID: 8538178.
      Citations: 16     Fields:    Translation:Animals
    341. West JL, Hubbell JA. Comparison of covalently and physically cross-linked polyethylene glycol-based hydrogels for the prevention of postoperative adhesions in a rat model. Biomaterials. 1995 Oct; 16(15):1153-6. PMID: 8562791.
      Citations: 14     Fields:    Translation:Animals
    342. Hubbell JA. Biomaterials in tissue engineering. Biotechnology (N Y). 1995 Jun; 13(6):565-76. PMID: 9634795.
      Citations: 148     Fields:    Translation:HumansCells
    343. Dumanian GA, Dascombe W, Hong C, Labadie K, Garrett K, Sawhney AS, Pathak CP, Hubbell JA, Johnson PC. A new photopolymerizable blood vessel glue that seals human vessel anastomoses without augmenting thrombogenicity. Plast Reconstr Surg. 1995 Apr; 95(5):901-7. PMID: 7708875.
      Citations: 5     Fields:    Translation:HumansCells
    344. Quinn CP, Pathak CP, Heller A, Hubbell JA. Photo-crosslinked copolymers of 2-hydroxyethyl methacrylate, poly(ethylene glycol) tetra-acrylate and ethylene dimethacrylate for improving biocompatibility of biosensors. Biomaterials. 1995 Mar; 16(5):389-96. PMID: 7662824.
      Citations: 24     Fields:    Translation:Animals
    345. Drumheller PD, Hubbell JA. Densely crosslinked polymer networks of poly(ethylene glycol) in trimethylolpropane triacrylate for cell-adhesion-resistant surfaces. J Biomed Mater Res. 1995 Feb; 29(2):207-15. PMID: 7738068.
      Citations: 13     Fields:    Translation:HumansCells
    346. Frautschi JR, Eberhart RC, Hubbell JA. Alkylated cellulosic membranes with enhanced albumin affinity: influence of competing proteins. J Biomater Sci Polym Ed. 1995; 7(7):563-75. PMID: 8924423.
      Citations: 2     Fields:    Translation:Cells
    347. Drumheller PD, Hubbell JA. Polymer networks with grafted cell adhesion peptides for highly biospecific cell adhesive substrates. Anal Biochem. 1994 Nov 01; 222(2):380-8. PMID: 7864362.
      Citations: 19     Fields:    Translation:Cells
    348. Quinn CP, Schmidtke DW, Lindquist SE, Pishko MV, Ye L, Katakis I, Hubbell JA, Heller A, Csöregi E. Design, characterization, and one-point in vivo calibration of a subcutaneously implanted glucose electrode. Anal Chem. 1994 Oct 01; 66(19):3131-8. PMID: 7978306.
      Citations: 6     Fields:    Translation:AnimalsCells
    349. Hill-West JL, Chowdhury SM, Dunn RC, Hubbell JA. Efficacy of a resorbable hydrogel barrier, oxidized regenerated cellulose, and hyaluronic acid in the prevention of ovarian adhesions in a rabbit model. Fertil Steril. 1994 Sep; 62(3):630-4. PMID: 8062961.
      Citations: 5     Fields:    Translation:AnimalsCells
    350. Hossainy SF, Hubbell JA. Molecular weight dependence of calcification of polyethylene glycol hydrogels. Biomaterials. 1994 Sep; 15(11):921-5. PMID: 7833441.
      Citations: 4     Fields:    Translation:Animals
    351. Sawhney AS, Pathak CP, van Rensburg JJ, Dunn RC, Hubbell JA. Optimization of photopolymerized bioerodible hydrogel properties for adhesion prevention. J Biomed Mater Res. 1994 Jul; 28(7):831-8. PMID: 8083251.
      Citations: 27     Fields:    Translation:Animals
    352. Sawhney AS, Pathak CP, Hubbell JA. Modification of islet of langerhans surfaces with immunoprotective poly(ethylene glycol) coatings via interfacial photopolymerization. Biotechnol Bioeng. 1994 Jul; 44(3):383-6. PMID: 18618756.
      Citations: 14     Fields:    
    353. Hill-West JL, Chowdhury SM, Slepian MJ, Hubbell JA. Inhibition of thrombosis and intimal thickening by in situ photopolymerization of thin hydrogel barriers. Proc Natl Acad Sci U S A. 1994 Jun 21; 91(13):5967-71. PMID: 8016098; PMCID: PMC44118.
      Citations: 29     Fields:    Translation:HumansAnimals
    354. Hubbell JA, Palsson BO, Papoutsakis ET. Preface: Tissue engineering and cell therapies: II. Biotechnol Bioeng. 1994 Apr 05; 43(8):683. PMID: 18615791.
      Citations: 2     Fields:    
    355. Drumheller PD, Elbert DL, Hubbell JA. Multifunctional poly(ethylene glycol) semi-interpenetrating polymer networks as highly selective adhesive substrates for bioadhesive peptide grafting. Biotechnol Bioeng. 1994 Apr 05; 43(8):772-80. PMID: 18615801.
      Citations: 9     Fields:    
    356. Hubbell JA, Palsson BO, Papoutsakis ET. Preface. Tissue engineering and cell therapies. Biotechnol Bioeng. 1994 Mar 25; 43(7):541. PMID: 18615753.
      Citations: 1     Fields:    
    357. Pathak CP, Sawhney AS, Quinn CP, Hubbell JA. Polyimide-polyethylene glycol block copolymers: synthesis, characterization, and initial evaluation as a biomaterial. J Biomater Sci Polym Ed. 1994; 6(4):313-23. PMID: 7841141.
      Citations: 3     Fields:    Translation:HumansCells
    358. Hill-West JL, Chowdhury SM, Sawhney AS, Pathak CP, Dunn RC, Hubbell JA. Prevention of postoperative adhesions in the rat by in situ photopolymerization of bioresorbable hydrogel barriers. Obstet Gynecol. 1994 Jan; 83(1):59-64. PMID: 8272310.
      Citations: 18     Fields:    Translation:AnimalsPHPublic Health
    359. Sawhney AS, Pathak CP, Hubbell JA. Interfacial photopolymerization of poly(ethylene glycol)-based hydrogels upon alginate-poly(l-lysine) microcapsules for enhanced biocompatibility. Biomaterials. 1993 Oct; 14(13):1008-16. PMID: 8286667.
      Citations: 30     Fields:    Translation:AnimalsCells
    360. Massia SP, Rao SS, Hubbell JA. Covalently immobilized laminin peptide Tyr-Ile-Gly-Ser-Arg (YIGSR) supports cell spreading and co-localization of the 67-kilodalton laminin receptor with alpha-actinin and vinculin. J Biol Chem. 1993 Apr 15; 268(11):8053-9. PMID: 8463322.
      Citations: 40     Fields:    Translation:HumansAnimalsCells
    361. Hossiany SF, Desai NP, Hubbell JA. Avoidance of photoactivation in the epifluorescence video microscopic observation of thrombosis. J Biomed Mater Res. 1992 Nov; 26(11):1535-42. PMID: 1447234.
      Citations:    Fields:    Translation:HumansCells
    362. Hubbell JA, Massia SP, Drumheller PD. Surface-grafted cell-binding peptides in tissue engineering of the vascular graft. Ann N Y Acad Sci. 1992 Oct 13; 665:253-8. PMID: 1416607.
      Citations: 5     Fields:    Translation:HumansCells
    363. Massia SP, Hubbell JA. Vascular endothelial cell adhesion and spreading promoted by the peptide REDV of the IIICS region of plasma fibronectin is mediated by integrin alpha 4 beta 1. J Biol Chem. 1992 Jul 15; 267(20):14019-26. PMID: 1629200.
      Citations: 53     Fields:    Translation:HumansCells
    364. Massia SP, Hubbell JA. Immobilized amines and basic amino acids as mimetic heparin-binding domains for cell surface proteoglycan-mediated adhesion. J Biol Chem. 1992 May 15; 267(14):10133-41. PMID: 1577783.
      Citations: 8     Fields:    Translation:Cells
    365. Massia SP, Hubbell JA. Tissue engineering in the vascular graft. Cytotechnology. 1992; 10(3):189-204. PMID: 1369235.
      Citations: 3     Fields:    Translation:HumansCells
    366. Desai NP, Hubbell JA. Tissue response to intraperitoneal implants of polyethylene oxide-modified polyethylene terephthalate. Biomaterials. 1992; 13(8):505-10. PMID: 1385984.
      Citations: 3     Fields:    Translation:Animals
    367. Sawhney AS, Hubbell JA. Poly(ethylene oxide)-graft-poly(L-lysine) copolymers to enhance the biocompatibility of poly(L-lysine)-alginate microcapsule membranes. Biomaterials. 1992; 13(12):863-70. PMID: 1457680.
      Citations: 17     Fields:    Translation:AnimalsCells
    368. Desai NP, Hossainy SF, Hubbell JA. Surface-immobilized polyethylene oxide for bacterial repellence. Biomaterials. 1992; 13(7):417-20. PMID: 1385983.
      Citations: 17     Fields:    Translation:HumansCells
    369. Massia SP, Hubbell JA. An RGD spacing of 440 nm is sufficient for integrin alpha V beta 3-mediated fibroblast spreading and 140 nm for focal contact and stress fiber formation. J Cell Biol. 1991 Sep; 114(5):1089-100. PMID: 1714913; PMCID: PMC2289117.
      Citations: 139     Fields:    Translation:HumansCells
    370. Desai NP, Hubbell JA. Biological responses to polyethylene oxide modified polyethylene terephthalate surfaces. J Biomed Mater Res. 1991 Jul; 25(7):829-43. PMID: 1833405.
      Citations: 24     Fields:    Translation:HumansCells
    371. Hubbell JA, Massia SP, Desai NP, Drumheller PD. Endothelial cell-selective materials for tissue engineering in the vascular graft via a new receptor. Biotechnology (N Y). 1991 Jun; 9(6):568-72. PMID: 1369319.
      Citations: 48     Fields:    Translation:HumansCells
    372. Desai NP, Hubbell JA. Solution technique to incorporate polyethylene oxide and other water-soluble polymers into surfaces of polymeric biomaterials. Biomaterials. 1991 Mar; 12(2):144-53. PMID: 1831675.
      Citations: 16     Fields:    Translation:Cells
    373. Massia SP, Hubbell JA. Human endothelial cell interactions with surface-coupled adhesion peptides on a nonadhesive glass substrate and two polymeric biomaterials. J Biomed Mater Res. 1991 Feb; 25(2):223-42. PMID: 1829082.
      Citations: 28     Fields:    Translation:HumansCells
    374. Wagner WR, Hubbell JA. Local thrombin synthesis and fibrin formation in an in vitro thrombosis model result in platelet recruitment and thrombus stabilization on collagen in heparinized blood. J Lab Clin Med. 1990 Nov; 116(5):636-50. PMID: 2104522.
      Citations: 12     Fields:    Translation:HumansCells
    375. Sawhney AS, Hubbell JA. Rapidly degraded terpolymers of dl-lactide, glycolide, and epsilon-caprolactone with increased hydrophilicity by copolymerization with polyethers. J Biomed Mater Res. 1990 Oct; 24(10):1397-411. PMID: 2283356.
      Citations: 10     Fields:    
    376. Massia SP, Hubbell JA. Covalent surface immobilization of Arg-Gly-Asp- and Tyr-Ile-Gly-Ser-Arg-containing peptides to obtain well-defined cell-adhesive substrates. Anal Biochem. 1990 Jun; 187(2):292-301. PMID: 2382830.
      Citations: 44     Fields:    Translation:HumansCells
    377. Massia SP, Hubbell JA. Covalently attached GRGD on polymer surfaces promotes biospecific adhesion of mammalian cells. Ann N Y Acad Sci. 1990; 589:261-70. PMID: 2141461.
      Citations: 16     Fields:    Translation:AnimalsCells
    378. Desai NP, Hubbell JA. The short-term blood biocompatibility of poly(hydroxyethyl methacrylate-co-methyl methacrylate) in an in vitro flow system measured by digital videomicroscopy. J Biomater Sci Polym Ed. 1989; 1(2):123-46. PMID: 2488848.
      Citations:    Fields:    
    379. Hubbell JA, McIntire LV. Visualization and analysis of mural thrombogenesis on collagen, polyurethane and nylon. Biomaterials. 1986 Sep; 7(5):354-63. PMID: 3778995.
      Citations: 24     Fields:    Translation:HumansCells
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