"Bradykinin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A nonapeptide messenger that is enzymatically produced from KALLIDIN in the blood where it is a potent but short-lived agent of arteriolar dilation and increased capillary permeability. Bradykinin is also released from MAST CELLS during asthma attacks, from gut walls as a gastrointestinal vasodilator, from damaged tissues as a pain signal, and may be a neurotransmitter.
| Descriptor ID |
D001920
|
| MeSH Number(s) |
D12.644.276.812.169 D12.644.400.090 D12.644.456.193 D12.776.467.812.169 D12.776.631.650.090 D23.469.050.375.110 D23.529.812.169
|
| Concept/Terms |
Bradykinin- Bradykinin
- Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg
- Arg Pro Pro Gly Phe Ser Pro Phe Arg
|
Below are MeSH descriptors whose meaning is more general than "Bradykinin".
Below are MeSH descriptors whose meaning is more specific than "Bradykinin".
This graph shows the total number of publications written about "Bradykinin" by people in this website by year, and whether "Bradykinin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 |
| 1996 | 2 | 1 | 3 |
| 1997 | 0 | 3 | 3 |
| 1998 | 0 | 2 | 2 |
| 2000 | 1 | 1 | 2 |
| 2003 | 1 | 1 | 2 |
| 2005 | 0 | 2 | 2 |
| 2006 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
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Below are the most recent publications written about "Bradykinin" by people in Profiles.
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Defining modulatory inputs into CNS neuronal subclasses by functional pharmacological profiling. Proc Natl Acad Sci U S A. 2014 Apr 29; 111(17):6449-54.
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Comparison of activity characteristics of the cuneate nucleus and thoracic spinal neurons receiving noxious cardiac and/or somatic inputs in rats. Brain Res. 2010 Jul 30; 1346:102-11.
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Bradykinin is involved in the mediation of cardiac nociception during ischemia through upper thoracic spinal neurons. Curr Neurovasc Res. 2009 May; 6(2):89-94.
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Intraesophageal chemicals enhance responsiveness of upper thoracic spinal neurons to mechanical stimulation of esophagus in rats. Am J Physiol Gastrointest Liver Physiol. 2008 Mar; 294(3):G708-16.
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Gastrocardiac afferent convergence in upper thoracic spinal neurons: a central mechanism of postprandial angina pectoris. J Pain. 2007 Jun; 8(6):522-9.
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Characterization of thoracic spinal neurons with noxious convergent inputs from heart and lower airways in rats. Brain Res. 2007 Apr 13; 1141:84-91.
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Tyrosine phosphatase and cytochrome P450 activity are critical in regulating store-operated calcium channels in human fibroblasts. Exp Mol Med. 2006 Dec 31; 38(6):703-17.
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Bradykinin B2 receptors mediate pulmonary sympathetic afferents induced reflexes in rabbits. Life Sci. 2006 Mar 20; 78(17):1990-7.
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The chemokine stromal cell-derived factor-1 regulates the migration of sensory neuron progenitors. J Neurosci. 2005 Apr 20; 25(16):3995-4003.
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Role of the B1 kinin receptor in the regulation of cardiac function and remodeling after myocardial infarction. Hypertension. 2005 Apr; 45(4):747-53.