"Kininogens" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Endogenous peptides present in most body fluids. Certain enzymes convert them to active KININS which are involved in inflammation, blood clotting, complement reactions, etc. Kininogens belong to the cystatin superfamily. They are cysteine proteinase inhibitors. HIGH-MOLECULAR-WEIGHT KININOGEN; (HMWK); is split by plasma kallikrein to produce BRADYKININ. LOW-MOLECULAR-WEIGHT KININOGEN; (LMWK); is split by tissue kallikrein to produce KALLIDIN.
| Descriptor ID |
D007704
|
| MeSH Number(s) |
D12.644.276.812.654 D12.776.124.125.635 D12.776.467.812.654 D12.776.811.420 D23.119.630 D23.469.050.375.425 D23.529.812.654
|
| Concept/Terms |
Kininogens- Kininogens
- Prokinins
- Prekinins
- Cystatins, Kininogen
- Kininogen Cystatins
|
Below are MeSH descriptors whose meaning is more general than "Kininogens".
Below are MeSH descriptors whose meaning is more specific than "Kininogens".
This graph shows the total number of publications written about "Kininogens" by people in this website by year, and whether "Kininogens" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 1 | 0 | 1 |
| 2019 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Kininogens" by people in Profiles.
-
Ablation of adipocyte creatine transport impairs thermogenesis and causes diet-induced obesity. Nat Metab. 2019; 1(3):360-370.
-
Kininogen gene (KNG) variation has a consistent effect on aldosterone response to antihypertensive drug therapy: the GERA study. Physiol Genomics. 2009 Sep 09; 39(1):56-60.
-
Quality assessment of heparin coatings by their binding capacities of coagulation and complement enzymes. J Biomater Appl. 2000 Jul; 15(1):8-22.
-
Plasma kallikrein during experimentally induced allergic rhinitis: role in kinin formation and contribution to TAME-esterase activity in nasal secretions. J Immunol. 1986 Aug 01; 137(3):977-82.
-
Inflammatory mediators in nasal secretions during induced rhinitis. Clin Allergy. 1986 Mar; 16(2):101-10.
-
Kininogens in nasal secretions after allergen challenge. Adv Exp Med Biol. 1986; 198 Pt B:189-92.
-
Influx of kininogens into nasal secretions after antigen challenge of allergic individuals. J Clin Invest. 1985 Jul; 76(1):191-7.