 Crossing Over, Genetic
"Crossing Over, Genetic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The reciprocal exchange of segments at corresponding positions along pairs of homologous CHROMOSOMES by symmetrical breakage and crosswise rejoining forming cross-over sites (HOLLIDAY JUNCTIONS) that are resolved during CHROMOSOME SEGREGATION. Crossing-over typically occurs during MEIOSIS but it may also occur in the absence of meiosis, for example, with bacterial chromosomes, organelle chromosomes, or somatic cell nuclear chromosomes.
| Descriptor ID |
D003434
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| MeSH Number(s) |
G05.355.760.615.200
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| Concept/Terms |
Crossing Over, Genetic- Crossing Over, Genetic
- Genetic Crossing Over
- Crossing-Over, Genetic
- Genetic Crossing-Over
- Crossing Over
- Crossing Overs
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Below are MeSH descriptors whose meaning is more general than "Crossing Over, Genetic".
Below are MeSH descriptors whose meaning is more specific than "Crossing Over, Genetic".
This graph shows the total number of publications written about "Crossing Over, Genetic" by people in this website by year, and whether "Crossing Over, Genetic" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1991 | 0 | 1 | 1 | | 1994 | 1 | 2 | 3 | | 1995 | 3 | 0 | 3 | | 1997 | 1 | 0 | 1 | | 1999 | 0 | 1 | 1 | | 2001 | 1 | 1 | 2 | | 2003 | 0 | 2 | 2 | | 2005 | 0 | 1 | 1 | | 2006 | 2 | 2 | 4 | | 2007 | 0 | 1 | 1 | | 2008 | 1 | 0 | 1 | | 2009 | 0 | 1 | 1 | | 2013 | 1 | 0 | 1 | | 2015 | 2 | 0 | 2 | | 2019 | 1 | 1 | 2 |
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Below are the most recent publications written about "Crossing Over, Genetic" by people in Profiles.
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Reitz D, Grubb J, Bishop DK. A mutant form of Dmc1 that bypasses the requirement for accessory protein Mei5-Sae3 reveals independent activities of Mei5-Sae3 and Rad51 in Dmc1 filament stability. PLoS Genet. 2019 12; 15(12):e1008217.
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Shinohara M, Bishop DK, Shinohara A. Distinct Functions in Regulation of Meiotic Crossovers for DNA Damage Response Clamp Loader Rad24(Rad17) and Mec1(ATR) Kinase. Genetics. 2019 12; 213(4):1255-1269.
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Williams AL, Genovese G, Dyer T, Altemose N, Truax K, Jun G, Patterson N, Myers SR, Curran JE, Duggirala R, Blangero J, Reich D, Przeworski M. Non-crossover gene conversions show strong GC bias and unexpected clustering in humans. Elife. 2015 Mar 25; 4.
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Shinohara M, Hayashihara K, Grubb JT, Bishop DK, Shinohara A. DNA damage response clamp 9-1-1 promotes assembly of ZMM proteins for formation of crossovers and synaptonemal complex. J Cell Sci. 2015 Apr 15; 128(8):1494-506.
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Lao JP, Cloud V, Huang CC, Grubb J, Thacker D, Lee CY, Dresser ME, Hunter N, Bishop DK. Meiotic crossover control by concerted action of Rad51-Dmc1 in homolog template bias and robust homeostatic regulation. PLoS Genet. 2013; 9(12):e1003978.
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Berchowitz LE, Hanlon SE, Lieb JD, Copenhaver GP. A positive but complex association between meiotic double-strand break hotspots and open chromatin in Saccharomyces cerevisiae. Genome Res. 2009 Dec; 19(12):2245-57.
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Fledel-Alon A, Wilson DJ, Broman K, Wen X, Ober C, Coop G, Przeworski M. Broad-scale recombination patterns underlying proper disjunction in humans. PLoS Genet. 2009 Sep; 5(9):e1000658.
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Coop G, Wen X, Ober C, Pritchard JK, Przeworski M. High-resolution mapping of crossovers reveals extensive variation in fine-scale recombination patterns among humans. Science. 2008 Mar 07; 319(5868):1395-8.
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McMahill MS, Sham CW, Bishop DK. Synthesis-dependent strand annealing in meiosis. PLoS Biol. 2007 Nov 06; 5(11):e299.
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Bishop DK. Multiple mechanisms of meiotic recombination. Cell. 2006 Dec 15; 127(6):1095-7.
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