 Ciguatoxins
"Ciguatoxins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Polycyclic ethers produced by Gambierdiscus (DINOFLAGELLATES) from gambiertoxins, which are ingested by fish which in turn may be ingested by humans who are susceptible to the CIGUATERA POISONING.
| Descriptor ID |
D002922
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| MeSH Number(s) |
D02.355.291.205 D23.946.580.160
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Ciguatoxins".
Below are MeSH descriptors whose meaning is more specific than "Ciguatoxins".
This graph shows the total number of publications written about "Ciguatoxins" by people in this website by year, and whether "Ciguatoxins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 1 | 0 | 1 | | 2013 | 1 | 0 | 1 | | 2016 | 2 | 0 | 2 |
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Below are the most recent publications written about "Ciguatoxins" by people in Profiles.
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MartÃnez-Morales E, Kopljar I, Rainier JD, Tytgat J, Snyders DJ, Labro AJ. Gambierol and n-alkanols inhibit Shaker Kv channel via distinct binding sites outside the K(+) pore. Toxicon. 2016 Sep 15; 120:57-60.
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Kopljar I, Grottesi A, de Block T, Rainier JD, Tytgat J, Labro AJ, Snyders DJ. Voltage-sensor conformation shapes the intra-membrane drug binding site that determines gambierol affinity in Kv channels. Neuropharmacology. 2016 08; 107:160-167.
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Kopljar I, Labro AJ, de Block T, Rainier JD, Tytgat J, Snyders DJ. The ladder-shaped polyether toxin gambierol anchors the gating machinery of Kv3.1 channels in the resting state. J Gen Physiol. 2013 Mar; 141(3):359-69.
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Kopljar I, Labro AJ, Cuypers E, Johnson HW, Rainier JD, Tytgat J, Snyders DJ. A polyether biotoxin binding site on the lipid-exposed face of the pore domain of Kv channels revealed by the marine toxin gambierol. Proc Natl Acad Sci U S A. 2009 Jun 16; 106(24):9896-901.
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