"Charybdotoxin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 37-amino acid residue peptide isolated from the scorpion Leiurus quinquestriatus hebraeus. It is a neurotoxin that inhibits calcium activated potassium channels.
| Descriptor ID |
D018999
|
| MeSH Number(s) |
D12.644.115 D20.888.065.830.150 D23.946.833.065.830.150
|
| Concept/Terms |
Charybdotoxin- Charybdotoxin
- CTX Toxin
- Toxin, CTX
- Quinquestriatus Toxin
- Toxin, Quinquestriatus
- ChTX
|
Below are MeSH descriptors whose meaning is more general than "Charybdotoxin".
Below are MeSH descriptors whose meaning is more specific than "Charybdotoxin".
This graph shows the total number of publications written about "Charybdotoxin" by people in this website by year, and whether "Charybdotoxin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 1996 | 0 | 1 | 1 |
| 2000 | 0 | 2 | 2 |
| 2003 | 1 | 1 | 2 |
| 2004 | 1 | 0 | 1 |
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Below are the most recent publications written about "Charybdotoxin" by people in Profiles.
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K+ channel inhibition accelerates intestinal epithelial cell wound healing. Wound Repair Regen. 2004 Sep-Oct; 12(5):565-74.
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Charybdotoxin binding in the I(Ks) pore demonstrates two MinK subunits in each channel complex. Neuron. 2003 Sep 25; 40(1):15-23.
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Small-conductance calcium-activated K+ channels are expressed in pancreatic islets and regulate glucose responses. Diabetes. 2003 Aug; 52(8):2000-6.
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The large conductance Ca2+-activated potassium channel (pSlo) of the cockroach Periplaneta americana: structure, localization in neurons and electrophysiology. Eur J Neurosci. 2003 Mar; 17(6):1197-212.
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Voltage-gated potassium channels in human ductus arteriosus. Lancet. 2000 Jul 08; 356(9224):134-7.
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A novel nervous system beta subunit that downregulates human large conductance calcium-dependent potassium channels. J Neurosci. 2000 May 15; 20(10):3563-70.
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A model of scorpion toxin binding to voltage-gated K+ channels. J Membr Biol. 1997 Aug 01; 158(3):187-96.
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Oxygen causes fetal pulmonary vasodilation through activation of a calcium-dependent potassium channel. Proc Natl Acad Sci U S A. 1996 Jul 23; 93(15):8089-94.
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Nitric oxide and cGMP cause vasorelaxation by activation of a charybdotoxin-sensitive K channel by cGMP-dependent protein kinase. Proc Natl Acad Sci U S A. 1994 Aug 02; 91(16):7583-7.