 Diphenhydramine
"Diphenhydramine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.
| Descriptor ID |
D004155
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| MeSH Number(s) |
D02.092.471.320 D02.455.426.559.389.115.250
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| Concept/Terms |
Diphenhydramine- Diphenhydramine
- Diphenylhydramine
- Benzhydramine
- Diphenylhydramin
- 2-Diphenylmethoxy-N,N-dimethylethylamine
- Benhydramin
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Below are MeSH descriptors whose meaning is more general than "Diphenhydramine".
Below are MeSH descriptors whose meaning is more specific than "Diphenhydramine".
This graph shows the total number of publications written about "Diphenhydramine" by people in this website by year, and whether "Diphenhydramine" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1988 | 1 | 0 | 1 | | 1989 | 0 | 1 | 1 | | 1992 | 1 | 0 | 1 | | 1993 | 0 | 3 | 3 | | 1996 | 1 | 0 | 1 | | 1998 | 0 | 1 | 1 | | 1999 | 1 | 1 | 2 | | 2000 | 0 | 1 | 1 | | 2003 | 1 | 0 | 1 | | 2008 | 0 | 1 | 1 | | 2013 | 1 | 0 | 1 | | 2017 | 1 | 0 | 1 | | 2018 | 1 | 1 | 2 |
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Below are the most recent publications written about "Diphenhydramine" by people in Profiles.
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Conte WL, Arndt N, Cipriani VP, Dellaria A, Javed A. Reduction in ocrelizumab-induced infusion reactions by a modified premedication protocol. Mult Scler Relat Disord. 2019 Jan; 27:397-399.
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Wang C, Chopade SA, Guo Y, Early JT, Tang B, Wang E, Hillmyer MA, Lodge TP, Sun CC. Preparation, Characterization, and Formulation Development of Drug-Drug Protic Ionic Liquids of Diphenhydramine with Ibuprofen and Naproxen. Mol Pharm. 2018 09 04; 15(9):4190-4201.
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Wang C, Hu S, Sun CC. Expedited Development of Diphenhydramine Orally Disintegrating Tablet through Integrated Crystal and Particle Engineering. Mol Pharm. 2017 10 02; 14(10):3399-3408.
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Gunderson EW, Kirkpatrick MG, Willing LM, Holstege CP. Intranasal substituted cathinone "bath salts" psychosis potentially exacerbated by diphenhydramine. J Addict Med. 2013 May-Jun; 7(3):163-8.
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Jang DH, Manini AF, Trueger NS, Duque D, Nestor NB, Nelson LS, Hoffman RS. Status epilepticus and wide-complex tachycardia secondary to diphenhydramine overdose. Clin Toxicol (Phila). 2010 Nov; 48(9):945-8.
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Dubow JS, Panush SR, Rezak M, Leikin J. Acute dystonic reaction associated with foscarnet administration. Am J Ther. 2008 Mar-Apr; 15(2):184-6.
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Stucka KR, Mycyk MB, Leikin JB, Pallasch EM. Rhabdomyolysis associated with unintentional antihistamine overdose in a child. Pediatr Emerg Care. 2003 Feb; 19(1):25-6.
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Lynch JP, Renz CL, Laroche D, Moss J. Value of baseline levels in assessing tryptase release. Inflamm Res. 2000 Apr; 49 Suppl 1:S23-4.
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Burda A, Webster K, Leikin JB, Chan SB, Stokes KA. Nefazadone-induced acute dystonic reaction. Vet Hum Toxicol. 1999 Oct; 41(5):321-2.
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Renz CL, Thurn JD, Finn HA, Lynch JP, Moss J. Antihistamine prophylaxis permits rapid vancomycin infusion. Crit Care Med. 1999 Sep; 27(9):1732-7.
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