"Terfenadine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A selective histamine H1-receptor antagonist devoid of central nervous system depressant activity. The drug was used for ALLERGY but withdrawn due to causing LONG QT SYNDROME.
| Descriptor ID |
D016593
|
| MeSH Number(s) |
D02.455.426.559.389.115.800 D03.383.621.855
|
| Concept/Terms |
Terfenadine- Terfenadine
- Terfenidine
- alpha-(4-(1,1-Dimethylethyl)phenyl)-4-(hydroxydiphenylmethyl)-1-piperdinebutanol
|
Below are MeSH descriptors whose meaning is more general than "Terfenadine".
Below are MeSH descriptors whose meaning is more specific than "Terfenadine".
This graph shows the total number of publications written about "Terfenadine" by people in this website by year, and whether "Terfenadine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 |
| 1995 | 1 | 0 | 1 |
| 1996 | 1 | 0 | 1 |
| 2001 | 0 | 1 | 1 |
| 2002 | 1 | 0 | 1 |
| 2004 | 1 | 0 | 1 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Terfenadine" by people in Profiles.
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Why fexofenadine is considered as a truly non-sedating antihistamine with no brain penetration: a systematic review. Curr Med Res Opin. 2024 Aug; 40(8):1297-1309.
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Comparison of the combinations of fexofenadine-pseudoephedrine and loratadine-montelukast in the treatment of seasonal allergic rhinitis. Ann Allergy Asthma Immunol. 2004 Jan; 92(1):73-9.
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Effects of fexofenadine on the early response to nasal allergen challenge. Ann Allergy Asthma Immunol. 2002 Dec; 89(6):578-84.
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Absence of nasal mucosal atrophy with fluticasone aqueous nasal spray. Arch Otolaryngol Head Neck Surg. 2001 Feb; 127(2):193-9.
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Effects of loratadine and terfenadine on the induced nasal allergic reaction. Arch Otolaryngol Head Neck Surg. 1996 Mar; 122(3):309-16.
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Terfenadine increases the QT interval in isolated guinea pig heart. J Cardiovasc Pharmacol. 1995 Jan; 25(1):30-4.
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The effect of terfenadine on unilateral nasal challenge with allergen. J Allergy Clin Immunol. 1994 Mar; 93(3):594-605.
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Effects of antihistamines on inflammatory mediators. Ann Allergy. 1993 Sep; 71(3):292-5.
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The effect of antihistamines on the immediate allergic response: a comparative review. Otolaryngol Head Neck Surg. 1993 Jun; 108(6):723-30.
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Comparison of the secretory response of the nasal mucosa to methacholine and histamine. J Appl Physiol (1985). 1993 Jun; 74(6):2661-71.