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Maanasa Raghavan

TitleAssistant Professor
InstitutionUniversity of Chicago
DepartmentHuman Genetics
AddressChicago IL 60637
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    My group's research interests span questions and applications in multiple fields, including population genetics/genomics, anthropology, archaeology, and medical genetics. The big question driving our research is: ‘How have demographic, cultural, and environmental factors contributed over time to shaping the genetic profiles of present-day human populations?’ In order to address specific research questions embedded within this overarching goal, we use a combined approach that brings together genome-scale data from present-day and ancient humans and their biotic environment, especially domesticates and pathogens. Through the implementation of multiple complementary projects set within the global context, our research will ultimately contribute towards the understanding of the evolutionary mechanisms that underlie adaptations and diseases among human populations.
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    Collapse education and training
    University of Copenhagen, DenmarkPhD12/2011Paleogenomics (ancient DNA)
    University of Oxford, UKMSc09/2007Archaeological Sciences
    University of Toronto, CanadaBSc (Hons)06/2006Molecular Biology
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    2018 - 2023Neubauer Family Assistant Professors Program, University of Chicago

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    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Biddanda A, Bandyopadhyay E, de la Fuente Castro C, Witonsky D, Urban Aragon JA, Pasupuleti N, Moots HM, Fonseca R, Freilich S, Stanisavic J, Willis T, Menon A, Mustak MS, Kodira CD, Naren AP, Sikdar M, Rai N, Raghavan M. Distinct positions of genetic and oral histories: Perspectives from India. HGG Adv. 2024 May 07; 100305. PMID: 38720459.
    2. Ávila-Arcos MC, Raghavan M, Schlebusch C. Going local with ancient DNA: A review of human histories from regional perspectives. Science. 2023 10 06; 382(6666):53-58. PMID: 37797024.
      Citations: 2     Fields:    Translation:Humans
    3. de la Fuente Castro C, Raghavan M, Ávila-Arcos MC, Nieves-Colón MA. Recommendations for Sustainable Ancient DNA Research in the Global South: Voices From a New Generation of Paleogenomicists. Front Genet. 2022; 13:880170. PMID: 35559028; PMCID: PMC9086539.
      Citations: 10     
    4. Silva CP, de la Fuente Castro C, Raghavan M, González Zarzar T, Tonko-Huenucoy A, Martínez FI, Montalva N. The Articulation of Genomics, Mestizaje, and Indigenous Identities in Chile: A Case Study of the Social Implications of Genomic Research in Light of Current Research Practices. Front Genet. 2022; 13:817318. PMID: 35309125; PMCID: PMC8927767.
      Citations: 4     
    5. Raghavan M, Schroeder H, Malaspinas AS. An Ancient Genome from the Indus Valley Civilization. Cell. 2019 10 17; 179(3):586-588. PMID: 31626767.
      Citations: 1     Fields:    Translation:Humans
    6. Seersholm FV, Pedersen MW, Shokry H, Mak SS, Ruter A, Raghavan M, Fitzhugh W, Willerslev E, Meldgaard M, Kapel CM, Hansen AJ, Søe MJ, Kjær KH. DNA evidence of bowhead whale exploitation by Greenlandic Paleo-Inuit 4,000 years ago. Nat Commun. 2016 11 08; 7:13389. PMID: 27824339; PMCID: PMC5105157.
      Citations: 11     Fields:    Translation:HumansAnimals
    7. Harris K, Schiffels S, Rasmussen S, DeGiorgio M, Eriksson A, Metspalu M, Homburger JR, Wall J, Cornejo OE, Lindo J, Metspalu E, Henrickson C, Shringarpure SS, Karmin M, Tambets K, Xue Y, Warmuth V, Friend AD, Singarayer J, Valdes P, Balloux F, Davis LG, Smith CI, Grimes V, Pike KA, Deal M, Fuller BT, Osipova L, Voevoda MI, Posukh OL, Balanovsky O, Lavryashina M, Bogunov Y, Khusnutdinova E, Balanovska E, Fedorova S, Litvinov S, Malyarchuk B, Derenko M, Mosher MJ, Archer D, Cybulski J, Petzelt B, Mitchell J, Worl R, Norman PJ, Parham P, Kemp BM, Kivisild T, Tyler-Smith C, Sandhu MS, Crawford M, Villems R, Smith DG, Waters MR, Goebel T, Johnson JR, Malhi RS, Manica A, Durbin R, Bustamante CD, Song YS, Nielsen R, Raghavan M, Steinrücken M, Albrechtsen A, Valdiosera C, Ávila-Arcos MC, Malaspinas AS, Moltke I, Moreno-Mayar JV, Korneliussen TS, Pierre T, Rasmussen M, Campos PF, de Barros Damgaard P, Allentoft ME, Rodríguez-Varela R, Mansilla J, Seguin-Orlando A, Malmström H, Stafford T, Moreno-Estrada A, Bergström A, Leboreiro I, Vera JL, Rangel-Villalobos H, Pettener D, Luiselli D, Heyer E, Zollikofer CPE, Ponce de León MS, Arriaza B, Standen V, Luz MF, Ricaut F, Guidon N, Gubina M, Jakobsson M, Meltzer DJ, Willerslev E. POPULATION GENETICS. Genomic evidence for the Pleistocene and recent population history of Native Americans. Science. 2015 Aug 21; 349(6250):aab3884. PMID: 26198033; PMCID: PMC4733658.
      Citations: 167     Fields:    Translation:Humans
    8. Der Sarkissian C, Allentoft ME, Barnett R, Campos PF, Cappellini E, Ermini L, da Fonseca R, Hansen AJ, Korneliussen T, Margaryan A, Martin MD, Raghavan M, Rasmussen M, Velasco MS, Schroeder H, Schubert M, Seguin-Orlando A, Wales N, Gilbert MT, Willerslev E, Orlando L, Ávila-Arcos MC, Fernández R, Ginolhac A, Jónsson H, Moreno-Mayar JV. Ancient genomics. Philos Trans R Soc Lond B Biol Sci. 2015 Jan 19; 370(1660):20130387. PMID: 25487338; PMCID: PMC4275894.
      Citations: 35     Fields:    Translation:HumansAnimals
    9. Schubert M, Chang D, Der Sarkissian C, Ermini L, Albrechtsen A, Dupanloup I, Foucal A, Petersen B, Fumagalli M, Raghavan M, Seguin-Orlando A, Korneliussen TS, Velazquez AM, Stenderup J, Hoover CA, Rubin CJ, Alfarhan AH, Alquraishi SA, Al-Rasheid KA, MacHugh DE, Kalbfleisch T, MacLeod JN, Rubin EM, Sicheritz-Ponten T, Andersson L, Hofreiter M, Gilbert MT, Nielsen R, Excoffier L, Willerslev E, Shapiro B, Orlando L, Jónsson H, Ginolhac A, Marques-Bonet T. Prehistoric genomes reveal the genetic foundation and cost of horse domestication. Proc Natl Acad Sci U S A. 2014 Dec 30; 111(52):E5661-9. PMID: 25512547; PMCID: PMC4284583.
      Citations: 123     Fields:    Translation:HumansAnimals
    10. Lao O, Sagredo FS, Rasmussen S, Johnson PL, Li M, DeGiorgio M, Duggan AT, Wang Y, Sicheritz-Ponten T, Hodges E, Hannon GJ, Price TD, Heinemeier J, Olsen J, Kayser M, Higham T, Stoneking M, Malaspinas AS, Schroeder H, Rasmussen M, Raghavan M, Moltke I, Campos PF, Gonçalves VF, Albrechtsen A, Allentoft ME, Reis S, Bernardo DV, Bastos M, Stenderup J, Moreno-Mayar JV, Brunak S, Orlando L, Jensen JD, Nielsen R, Rodrigues-Carvalho C, Lahr MM, Neves WA, Pena SD, Willerslev E. Two ancient human genomes reveal Polynesian ancestry among the indigenous Botocudos of Brazil. Curr Biol. 2014 Nov 03; 24(21):R1035-7. PMID: 25455029; PMCID: PMC4370112.
      Citations: 27     Fields:    Translation:Humans
    11. Clemente FJ, Cardona A, Inchley CE, Peter BM, Jacobs G, Pagani L, Lawson DJ, Mitt M, DeGiorgio M, Faltyskova Z, Xue Y, Ayub Q, Szpak M, Eriksson A, Manica A, Raghavan M, Rasmussen M, Rasmussen S, Willerslev E, Vidal-Puig A, Tyler-Smith C, Villems R, Nielsen R, Metspalu M, Malyarchuk B, Derenko M, Kivisild T, Antão T, Vicente M, Mägi R. A Selective Sweep on a Deleterious Mutation in CPT1A in Arctic Populations. Am J Hum Genet. 2014 11 06; 95(5):584-589. PMID: 25449608; PMCID: PMC4225582.
      Citations: 48     Fields:    
    12. Juras A, Dabert M, Kushniarevich A, Raghavan M, Kosicki JZ, Metspalu E, Willerslev E, Piontek J, Malmström H. Ancient DNA reveals matrilineal continuity in present-day Poland over the last two millennia. PLoS One. 2014; 9(10):e110839. PMID: 25337992; PMCID: PMC4206425.
      Citations: 9     Fields:    Translation:HumansCells
    13. DeGiorgio M, Albrechtsen A, Moltke I, Appelt M, Friesen TM, Fitzhugh W, Rasmussen S, Olsen J, Melchior L, Fuller BT, Fahrni SM, Grimes V, Renouf MA, Cybulski J, Lynnerup N, Lahr MM, Britton K, Knecht R, Arneborg J, Metspalu M, Cornejo OE, Wang Y, Raghavan V, Hansen TV, Khusnutdinova E, Dneprovsky K, Andreasen C, Lange H, Hayes MG, Coltrain J, Spitsyn VA, Kivisild T, Villems R, Crawford MH, Nielsen FC, Heinemeier J, Bustamante C, O'Rourke DH, Nielsen R, Raghavan M, Skoglund P, Korneliussen TS, Grønnow B, Gulløv HC, Malmström H, Stafford T, Malaspinas AS, Rasmussen M, Pierre T, Götherström A, Orlando L, Dissing J, Meldgaard M, Jakobsson M, Gilbert MT, Willerslev E. The genetic prehistory of the New World Arctic. Science. 2014 Aug 29; 345(6200):1255832. PMID: 25170159.
      Citations: 91     Fields:    Translation:HumansCells
    14. Fabre PH, Vilstrup JT, Raghavan M, Sarkissian CD, Willerslev E, Douzery EJ, Orlando L. Rodents of the Caribbean: origin and diversification of hutias unravelled by next-generation museomics. Biol Lett. 2014 Jul; 10(7). PMID: 25115033; PMCID: PMC4126619.
      Citations: 23     Fields:    Translation:AnimalsCells
    15. Skoglund P, Raghavan M, Valdiosera C, Hall P, Tambets K, Apel J, Willerslev E, Jakobsson M, Malmström H, Omrak A, Günther T, Parik J, Sjögren KG, Storå J, Götherström A. Genomic diversity and admixture differs for Stone-Age Scandinavian foragers and farmers. Science. 2014 May 16; 344(6185):747-50. PMID: 24762536.
      Citations: 140     Fields:    Translation:Humans
    16. Graf KE, Metspalu M, Rasmussen S, Metspalu E, Karmin M, Tambets K, Rootsi S, Balanovska E, Balanovsky O, Khusnutdinova E, Litvinov S, Osipova LP, Fedorova SA, Voevoda MI, DeGiorgio M, Sicheritz-Ponten T, Demeshchenko S, Kivisild T, Villems R, Nielsen R, Raghavan M, Skoglund P, Albrechtsen A, Moltke I, Stafford TW, Orlando L, Mägi R, Campos PF, Brunak S, Jakobsson M, Willerslev E. Upper Palaeolithic Siberian genome reveals dual ancestry of Native Americans. Nature. 2014 Jan 02; 505(7481):87-91. PMID: 24256729; PMCID: PMC4105016.
      Citations: 281     Fields:    Translation:HumansAnimalsCells
    17. Zhang G, Froese D, Albrechtsen A, Stiller M, Schubert M, Cappellini E, Petersen B, Moltke I, Johnson PL, Fumagalli M, Vilstrup JT, Raghavan M, Korneliussen T, Malaspinas AS, Vogt J, Szklarczyk D, Kelstrup CD, Vinther J, Dolocan A, Stenderup J, Velazquez AM, Cahill J, Rasmussen M, Wang X, Min J, Zazula GD, Seguin-Orlando A, Mortensen C, Magnussen K, Thompson JF, Weinstock J, Gregersen K, Rubin CJ, Miller DC, Antczak DF, Bertelsen MF, Al-Rasheid KA, Ryder O, Andersson L, Mundy J, Krogh A, Gilbert MT, Sicheritz-Ponten T, Jensen LJ, Olsen JV, Hofreiter M, Nielsen R, Shapiro B, Wang J, Willerslev E, Orlando L, Ginolhac A, Røed KH, Eisenmann V, Brunak S, Kjær K. Recalibrating Equus evolution using the genome sequence of an early Middle Pleistocene horse. Nature. 2013 Jul 04; 499(7456):74-8. PMID: 23803765.
      Citations: 286     Fields:    Translation:Animals
    18. Vilstrup JT, Seguin-Orlando A, Stiller M, Ginolhac A, Raghavan M, Nielsen SC, Weinstock J, Froese D, Vasiliev SK, Ovodov ND, Clary J, Helgen KM, Fleischer RC, Cooper A, Shapiro B, Orlando L. Mitochondrial phylogenomics of modern and ancient equids. PLoS One. 2013; 8(2):e55950. PMID: 23437078; PMCID: PMC3577844.
      Citations: 49     Fields:    Translation:Animals
    19. Jenkins DL, Davis LG, Stafford TW, Campos PF, Hockett B, Jones GT, Cummings LS, Yost C, Connolly TJ, Yohe RM, Gibbons SC, Raghavan M, Rasmussen M, Paijmans JL, Hofreiter M, Kemp BM, Barta JL, Monroe C, Gilbert MT, Willerslev E. Clovis age Western Stemmed projectile points and human coprolites at the Paisley Caves. Science. 2012 Jul 13; 337(6091):223-8. PMID: 22798611.
      Citations: 25     Fields:    Translation:HumansAnimals
    20. Skoglund P, Raghavan M, Hall P, Willerslev E, Gilbert MT, Jakobsson M, Malmström H, Storå J, Götherström A. Origins and genetic legacy of Neolithic farmers and hunter-gatherers in Europe. Science. 2012 Apr 27; 336(6080):466-9. PMID: 22539720.
      Citations: 199     Fields:    Translation:Humans
    21. Orlando L, Ginolhac A, Raghavan M, Vilstrup J, Rasmussen M, Magnussen K, Steinmann KE, Kapranov P, Thompson JF, Zazula G, Froese D, Moltke I, Shapiro B, Hofreiter M, Al-Rasheid KA, Gilbert MT, Willerslev E. True single-molecule DNA sequencing of a pleistocene horse bone. Genome Res. 2011 Oct; 21(10):1705-19. PMID: 21803858; PMCID: PMC3202287.
      Citations: 51     Fields:    Translation:Animals
    22. Raghavan M, McCullagh JS, Lynnerup N, Hedges RE. Amino acid delta13C analysis of hair proteins and bone collagen using liquid chromatography/isotope ratio mass spectrometry: paleodietary implications from intra-individual comparisons. Rapid Commun Mass Spectrom. 2010 Mar 15; 24(5):541-8. PMID: 20131322.
      Citations: 9     Fields:    Translation:Humans
    23. Rasmussen M, Li Y, Lindgreen S, Pedersen JS, Albrechtsen A, Moltke I, Metspalu M, Metspalu E, Kivisild T, Gupta R, Bertalan M, Nielsen K, Gilbert MT, Wang Y, Raghavan M, Campos PF, Kamp HM, Wilson AS, Gledhill A, Tridico S, Bunce M, Lorenzen ED, Binladen J, Guo X, Zhao J, Zhang X, Zhang H, Li Z, Chen M, Orlando L, Kristiansen K, Bak M, Tommerup N, Bendixen C, Pierre TL, Meldgaard M, Andreasen C, Fedorova SA, Osipova LP, Higham TF, Ramsey CB, Hansen TV, Nielsen FC, Crawford MH, Villems R, Nielsen R, Krogh A, Wang J, Willerslev E, Grønnow B, Brunak S, Sicheritz-Pontén T. Ancient human genome sequence of an extinct Palaeo-Eskimo. Nature. 2010 Feb 11; 463(7282):757-62. PMID: 20148029; PMCID: PMC3951495.
      Citations: 283     Fields:    Translation:Humans
    24. Papageorgopoulou C, Rentsch K, Raghavan M, Hofmann MI, Colacicco G, Bianucci R, Gallien V, Rühli F. Preservation of cell structures in a medieval infant brain: a paleohistological, paleogenetic, radiological and physico-chemical study. Neuroimage. 2010 Apr 15; 50(3):893-901. PMID: 20080189.
      Citations: 4     Fields:    Translation:HumansCells
    25. Suter B, Fetchko MJ, Imhof R, Graham CI, Stoffel-Studer I, Zbinden C, Raghavan M, Lopez L, Beneti L, Hort J, Fillingham J, Greenblatt JF, Giaever G, Nislow C, Stagljar I. Examining protein protein interactions using endogenously tagged yeast arrays: the cross-and-capture system. Genome Res. 2007 Dec; 17(12):1774-82. PMID: 17989249; PMCID: PMC2099586.
      Citations: 8     Fields:    Translation:Animals
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