The University of Chicago Header Logo

John Novembre

TitleProfessor
InstitutionUniversity of Chicago
DepartmentHuman Genetics
AddressChicago IL 60637
vCardDownload vCard

    Collapse Overview 
    Collapse overview
    The Novembre research group uses computational tools to study genetic diversity in natural populations. Our goal is to develop widely used statistical methods for intelligently extracting information from large-scale genomic data with the aim to improve understanding of: (1) basic genomic biology, (2) the biology of heritable disease traits, (3) the genetic basis of evolutionary processes, and (4) the history and evolution of various species, especially humans. From a disciplinary perspective, most of the ideas we use are from theoretical population genetics, statistical genetics, and computational statistics. Much of our work is invigorated by addressing data from emerging genotyping and sequencing technologies applied to large or particularly interesting population samples.

    Collapse Research 
    Collapse research activities and funding
    R35GM149521     (NOVEMBRE, JOHN)Jun 1, 2023 - May 31, 2028
    NIH
    Theory, Methods, and Resources for Understanding and Leveraging Spatial Variation in Population Genetic Data
    Role: Principal Investigator
    T32GM139782     (THORNTON, JOSEPH W)Jul 1, 2021 - Jun 30, 2026
    NIH
    Genetic Mechanisms and Evolution
    Role: Co-Principal Investigator
    R01HG010773     (HE, XIN)Sep 1, 2020 - Jun 30, 2024
    NIH
    Refining mutation rates and measures of purifying selection with an application to understanding the impact of non-coding variation on neuropsychiatric diseases
    Role: Co-Principal Investigator
    R01GM132383     (NOVEMBRE, JOHN)Apr 1, 2019 - Mar 31, 2023
    NIH
    Extending Tools for Visualization of Geographic Structure in Population Genomic Data
    Role: Principal Investigator
    U01CA198933     (NOVEMBRE, JOHN)Jun 1, 2015 - May 31, 2019
    NIH
    Tools for Visualization of Geographic Structure in Population Genomic Data
    Role: Principal Investigator
    R01GM108805     (CLARK, ANDREW G.)May 10, 2014 - Apr 30, 2019
    NIH
    Population Genetic Consequences of Recent Explosive Population Growth in Humans
    Role: Co-Principal Investigator
    R01HG007089     (NOVEMBRE, JOHN)Jan 1, 2013 - Dec 31, 2019
    NIH
    Haplotype-based analysis methods for population genomics
    Role: Principal Investigator

    Collapse Featured Content 
    Collapse Twitter

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Pearson NM, Novembre J. No evidence that ACE2 or TMPRSS2 drive population disparity in COVID risks. BMC Med. 2024 08 26; 22(1):337. PMID: 39183295; PMCID: PMC11346279.
      Citations:    Fields:    Translation:HumansCells
    2. Ober C, Joseph CLM, Novembre J. Population descriptors in asthma and allergy research: Time to regroup. J Allergy Clin Immunol. 2024 Jul; 154(1):79-81. PMID: 38642714.
      Citations:    Fields:    Translation:Humans
    3. Sohail M, Palma-Martínez MJ, Chong AY, Quinto-Cortés CD, Barberena-Jonas C, Medina-Muñoz SG, Ragsdale A, Delgado-Sánchez G, Cruz-Hervert LP, Ferreyra-Reyes L, Ferreira-Guerrero E, Mongua-Rodríguez N, Canizales-Quintero S, Jimenez-Kaufmann A, Moreno-Macías H, Aguilar-Salinas CA, Auckland K, Cortés A, Acuña-Alonzo V, Gignoux CR, Wojcik GL, Ioannidis AG, Fernández-Valverde SL, Hill AVS, Tusié-Luna MT, Mentzer AJ, Novembre J, García-García L, Moreno-Estrada A. Mexican Biobank advances population and medical genomics of diverse ancestries. Nature. 2023 Oct; 622(7984):775-783. PMID: 37821706; PMCID: PMC10600006.
      Citations: 21     Fields:    Translation:Humans
    4. Gloss AD, Steiner MC, Novembre J, Bergelson J. The design of mapping populations: Impacts of geographic scale on genetic architecture and mapping efficacy for defense and immunity. Curr Opin Plant Biol. 2023 08; 74:102399. PMID: 37307746; PMCID: PMC10441534.
      Citations:    Fields:    
    5. Cotter DJ, Hofgard EF, Novembre J, Szpiech ZA, Rosenberg NA. A rarefaction approach for measuring population differences in rare and common variation. Genetics. 2023 05 26; 224(2). PMID: 37075098; PMCID: PMC10213490.
      Citations: 1     Fields:    Translation:Humans
    6. Skeen HR, Willard DE, Jones AW, Winger BM, Gyllenhaal EF, Tsuru BR, Hackett SJ, Novembre J. Intestinal microbiota of Nearctic-Neotropical migratory birds vary more over seasons and years than between host species. Mol Ecol. 2023 06; 32(12):3290-3307. PMID: 36974685.
      Citations: 2     Fields:    Translation:Animals
    7. Muktupavela RA, Petr M, Korneliussen T, Novembre J, Racimo F, Ségurel L. Modeling the spatiotemporal spread of beneficial alleles using ancient genomes. Elife. 2022 12 20; 11. PMID: 36537881; PMCID: PMC9767474.
      Citations: 3     Fields:    Translation:Humans
    8. Novembre J, Stein C, Asgari S, Landstrom A, Lemke A, Li J, Mighton C, Taylor M, Tishkoff S, Gonzaga-Jauregui C. Addressing the challenges of polygenic scores in human genetic research. Am J Hum Genet. 2022 12 01; 109(12):2095-2100. PMID: 36459976; PMCID: PMC9808501.
      Citations: 17     Fields:    Translation:Humans
    9. Steiner MC, Novembre J. Population genetic models for the spatial spread of adaptive variants: A review in light of SARS-CoV-2 evolution. PLoS Genet. 2022 09; 18(9):e1010391. PMID: 36137003; PMCID: PMC9498967.
      Citations: 4     Fields:    Translation:HumansCellsPHPublic Health
    10. Biddanda A, Novembre J, Steinrücken M. Properties of 2-locus genealogies and linkage disequilibrium in temporally structured samples. Genetics. 2022 05 05; 221(1). PMID: 35294015; PMCID: PMC9245597.
      Citations: 2     Fields:    Translation:Humans
    11. Novembre J. The background and legacy of Lewontin's apportionment of human genetic diversity. Philos Trans R Soc Lond B Biol Sci. 2022 06 06; 377(1852):20200406. PMID: 35430890; PMCID: PMC9014184.
      Citations: 15     Fields:    Translation:Humans
    12. Lewis ACF, Molina SJ, Appelbaum PS, Dauda B, Di Rienzo A, Fuentes A, Fullerton SM, Garrison NA, Ghosh N, Hammonds EM, Jones DS, Kenny EE, Kraft P, Lee SS, Mauro M, Novembre J, Panofsky A, Sohail M, Neale BM, Allen DS. Getting genetic ancestry right for science and society. Science. 2022 04 15; 376(6590):250-252. PMID: 35420968; PMCID: PMC10135340.
      Citations: 73     Fields:    
    13. Lohmueller KE, Novembre J, Ortega-Del Vecchyo D. Haplotype-based inference of the distribution of fitness effects. Genetics. 2022 04 04; 220(4). PMID: 35100400; PMCID: PMC8982047.
      Citations: 2     Fields:    Translation:Humans
    14. Liu CC, Witonsky D, Gosling A, Lee JH, Ringbauer H, Hagan R, Patel N, Stahl R, Novembre J, Aldenderfer M, Warinner C, Di Rienzo A, Jeong C. Ancient genomes from the Himalayas illuminate the genetic history of Tibetans and their Tibeto-Burman speaking neighbors. Nat Commun. 2022 03 08; 13(1):1203. PMID: 35260549; PMCID: PMC8904508.
      Citations: 15     Fields:    Translation:Humans
    15. Greif G, Shin JY, Yoo SK, Seo JS, Robello C, Kim C, Novembre J, Naya H, Spangenberg L, Fariello MI, Arce D, Illanes G, Sans M. Indigenous Ancestry and Admixture in the Uruguayan Population. Front Genet. 2021; 12:733195. PMID: 34630523; PMCID: PMC8495321.
      Citations: 6     
    16. Ringbauer H, Novembre J, Steinrücken M. Parental relatedness through time revealed by runs of homozygosity in ancient DNA. Nat Commun. 2021 09 14; 12(1):5425. PMID: 34521843; PMCID: PMC8440622.
      Citations: 82     Fields:    Translation:Humans
    17. Marcus J, Ha W, Barber RF, Novembre J. Fast and flexible estimation of effective migration surfaces. Elife. 2021 07 30; 10. PMID: 34328078; PMCID: PMC8324296.
      Citations: 13     Fields:    Translation:Animals
    18. Zhang S, Johnson RA, Novembre J, Freeland E, Conley D. Public attitudes toward genetic risk scoring in medicine and beyond. Soc Sci Med. 2021 04; 274:113796. PMID: 33684700.
      Citations: 4     Fields:    Translation:Humans
    19. Biddanda A, Rice DP, Novembre J. A variant-centric perspective on geographic patterns of human allele frequency variation. Elife. 2020 12 22; 9. PMID: 33350384; PMCID: PMC7755386.
      Citations: 26     Fields:    Translation:Humans
    20. Peter BM, Petkova D, Novembre J. Genetic Landscapes Reveal How Human Genetic Diversity Aligns with Geography. Mol Biol Evol. 2020 04 01; 37(4):943-951. PMID: 31778174; PMCID: PMC7086171.
      Citations: 24     Fields:    Translation:Humans
    21. Marcus JH, Posth C, Ringbauer H, Lai L, Skeates R, Sidore C, Beckett J, Chiang CWK, Al-Asadi H, Dey K, Joseph TA, Liu CC, Radzeviciute R, Michel M, Gradoli MG, Rovina D, Bianucci R, Pompianu E, Guirguis M, Orquin RP, Tuross N, van Dommelen P, Haak W, Reich D, Schlessinger D, Cucca F, Krause J, Novembre J, Furtwängler A, Olivieri A, Der Sarkissian C, Marongiu P, Rubino S, Mazzarello V, La Fragola A, Serra RM, Bandiera P, Murgia C. Genetic history from the Middle Neolithic to present on the Mediterranean island of Sardinia. Nat Commun. 2020 02 24; 11(1):939. PMID: 32094358; PMCID: PMC7039977.
      Citations: 57     Fields:    Translation:HumansCells
    22. Liu CC, Shringarpure S, Lange K, Novembre J. Exploring Population Structure with Admixture Models and Principal Component Analysis. Methods Mol Biol. 2020; 2090:67-86. PMID: 31975164; PMCID: PMC8722024.
      Citations: 17     Fields:    Translation:Humans
    23. Schweizer RM, Stahler DR, Smith DW, Novembre J, Koch EM, Schweizer TM, Wayne RK. De Novo Mutation Rate Estimation in Wolves of Known Pedigree. Mol Biol Evol. 2019 Nov 01; 36(11):2536-2547. PMID: 31297530; PMCID: PMC6805234.
      Citations: 25     Fields:    
    24. Al-Asadi H, Dey KK, Novembre J, Stephens M. Inference and visualization of DNA damage patterns using a grade of membership model. Bioinformatics. 2019 04 15; 35(8):1292-1298. PMID: 30192911; PMCID: PMC6821257.
      Citations: 2     Fields:    Translation:Humans
    25. Al-Asadi H, Petkova D, Stephens M, Novembre J. Estimating recent migration and population-size surfaces. PLoS Genet. 2019 01; 15(1):e1007908. PMID: 30640906; PMCID: PMC6347299.
      Citations: 32     Fields:    Translation:Humans
    26. Dickson BG, Albano CM, Anantharaman R, Beier P, Fargione J, Graves TA, Gray ME, Hall KR, Lawler JJ, Leonard PB, Littlefield CE, McClure ML, Novembre J, Schloss CA, Schumaker NH, Shah VB, Theobald DM. Circuit-theory applications to connectivity science and conservation. Conserv Biol. 2019 04; 33(2):239-249. PMID: 30311266; PMCID: PMC6727660.
      Citations: 30     Fields:    Translation:Animals
    27. Lawler J, Beier P, Dickson B, Fargione J, Novembre J, Theobald D. A tribute to a true conservation innovator, Brad McRae, 1966-2017. Conserv Biol. 2019 Apr; 33(2):480-482. PMID: 30480336.
      Citations:    
    28. Lindo J, Haas R, Hofman C, Watson JT, Viviano Llave C, Witonsky D, Beall C, Warinner C, Novembre J, Aldenderfer M, Di Rienzo A, Apata M, Moraga M, Verdugo RA. The genetic prehistory of the Andean highlands 7000 years BP though European contact. Sci Adv. 2018 11; 4(11):eaau4921. PMID: 30417096; PMCID: PMC6224175.
      Citations: 53     Fields:    Translation:Humans
    29. Lawler J, Beier P, Dickson B, Fargione J, Novembre J, Theobald D. A tribute to a true conservation innovator, Brad McRae, 1966-2017. Conserv Biol. 2018 Oct 11. PMID: 30311257.
      Citations:    Fields:    
    30. Chiang CWK, Marcus JH, Sidore C, Biddanda A, Al-Asadi H, Zoledziewska M, Pitzalis M, Busonero F, Maschio A, Pistis G, Steri M, Angius A, Lohmueller KE, Abecasis GR, Schlessinger D, Cucca F, Novembre J. Genomic history of the Sardinian population. Nat Genet. 2018 10; 50(10):1426-1434. PMID: 30224645; PMCID: PMC6168346.
      Citations: 34     Fields:    Translation:Humans
    31. Jeong C, Witonsky DB, Basnyat B, Neupane M, Beall CM, Childs G, Craig SR, Novembre J, Di Rienzo A. Detecting past and ongoing natural selection among ethnically Tibetan women at high altitude in Nepal. PLoS Genet. 2018 09; 14(9):e1007650. PMID: 30188897; PMCID: PMC6143271.
      Citations: 35     Fields:    Translation:Humans
    32. Novembre J, Beier P, Fargione J, Lawler J, Selkoe K. Brad McRae (1966-2017). Mol Ecol. 2018 08; 27(15):3035-3036. PMID: 30133873.
      Citations:    Fields:    
    33. de Barros Damgaard P, Martiniano R, Kamm J, Kroonen G, Barjamovic G, Rasmussen S, Zacho C, Baimukhanov N, Zaibert V, Biddanda A, Loman V, Evdokimov V, Usmanova E, Hemphill B, Seguin-Orlando A, Yediay FE, Ullah I, Choin J, de la Fuente C, Ilardo M, Schroeder H, Moiseyev V, Gromov A, Polyakov A, Omura S, Ahmad H, McKenzie C, Margaryan A, Hameed A, Samad A, Gul N, Khokhar MH, Goriunova OI, Bazaliiskii VI, Novembre J, Weber AW, Orlando L, Allentoft ME, Nielsen R, Sikora M, Outram AK, Durbin R, Willerslev E, Moreno-Mayar JV, Peyrot M, Merz V, Merz I, Sjögren KG, Iversen KH, Senyurt SY, Kristiansen K. The first horse herders and the impact of early Bronze Age steppe expansions into Asia. Science. 2018 06 29; 360(6396). PMID: 29743352; PMCID: PMC6748862.
      Citations: 129     Fields:    Translation:HumansAnimalsCells
    34. Schweizer RM, Durvasula A, Smith J, Vohr SH, Stahler DR, Galaverni M, Thalmann O, Smith DW, Randi E, Ostrander EA, Green RE, Lohmueller KE, Novembre J, Wayne RK. Natural Selection and Origin of a Melanistic Allele in North American Gray Wolves. Mol Biol Evol. 2018 05 01; 35(5):1190-1209. PMID: 29688543; PMCID: PMC6455901.
      Citations: 17     Fields:    Translation:Animals
    35. Reppell M, Novembre J. Using pseudoalignment and base quality to accurately quantify microbial community composition. PLoS Comput Biol. 2018 04; 14(4):e1006096. PMID: 29659582; PMCID: PMC5945057.
      Citations: 8     Fields:    Translation:Humans
    36. Novembre J, Barton NH. Tread Lightly Interpreting Polygenic Tests of Selection. Genetics. 2018 Apr; 208(4):1351-1355. PMID: 29618592; PMCID: PMC5886544.
      Citations: 54     Fields:    
    37. Smith J, Coop G, Stephens M, Novembre J. Estimating Time to the Common Ancestor for a Beneficial Allele. Mol Biol Evol. 2018 04 01; 35(4):1003-1017. PMID: 29361025; PMCID: PMC5888984.
      Citations: 27     Fields:    Translation:Humans
    38. Serres-Armero A, Povolotskaya IS, Quilez J, Ramirez O, Santpere G, Kuderna LFK, Hernandez-Rodriguez J, Fernandez-Callejo M, Gomez-Sanchez D, Freedman AH, Fan Z, Novembre J, Navarro A, Boyko A, Wayne R, Lorente-Galdos B, Marques-Bonet T, Vilà C. Similar genomic proportions of copy number variation within gray wolves and modern dog breeds inferred from whole genome sequencing. BMC Genomics. 2017 Dec 19; 18(1):977. PMID: 29258433; PMCID: PMC5735816.
      Citations: 13     Fields:    Translation:AnimalsCells
    39. Jeong C, Peter BM, Basnyat B, Neupane M, Beall CM, Childs G, Craig SR, Novembre J, Di Rienzo A. Correction: A longitudinal cline characterizes the genetic structure of human populations in the Tibetan plateau. PLoS One. 2017; 12(8):e0183407. PMID: 28797074; PMCID: PMC5552323.
      Citations:    Fields:    
    40. Steri M, Orrù V, Idda ML, Pitzalis M, Pala M, Zara I, Sidore C, Faà V, Floris M, Deiana M, Asunis I, Porcu E, Mulas A, Piras MG, Lobina M, Lai S, Marongiu M, Serra V, Marongiu M, Sole G, Busonero F, Maschio A, Cusano R, Cuccuru G, Deidda F, Poddie F, Farina G, Dei M, Virdis F, Olla S, Satta MA, Pani M, Delitala A, Cocco E, Frau J, Coghe G, Lorefice L, Fenu G, Ferrigno P, Ban M, Barizzone N, Leone M, Guerini FR, Piga M, Firinu D, Kockum I, Lima Bomfim I, Olsson T, Alfredsson L, Suarez A, Carreira PE, Castillo-Palma MJ, Marcus JH, Congia M, Angius A, Melis M, Gonzalez A, Alarcón Riquelme ME, da Silva BM, Marchini M, Danieli MG, Del Giacco S, Mathieu A, Pani A, Montgomery SB, Rosati G, Hillert J, Sawcer S, D'Alfonso S, Todd JA, Novembre J, Abecasis GR, Whalen MB, Marrosu MG, Meloni A, Sanna S, Gorospe M, Schlessinger D, Fiorillo E, Zoledziewska M, Cucca F. Overexpression of the Cytokine BAFF and Autoimmunity Risk. N Engl J Med. 2017 04 27; 376(17):1615-1626. PMID: 28445677; PMCID: PMC5605835.
      Citations: 175     Fields:    Translation:HumansCells
    41. Jeong C, Peter BM, Basnyat B, Neupane M, Beall CM, Childs G, Craig SR, Novembre J, Di Rienzo A. A longitudinal cline characterizes the genetic structure of human populations in the Tibetan plateau. PLoS One. 2017; 12(4):e0175885. PMID: 28448508; PMCID: PMC5407838.
      Citations: 12     Fields:    Translation:Humans
    42. Pala M, Zappala Z, Marongiu M, Li X, Davis JR, Cusano R, Crobu F, Kukurba KR, Gloudemans MJ, Reinier F, Berutti R, Piras MG, Mulas A, Zoledziewska M, Marongiu M, Sorokin EP, Hess GT, Smith KS, Busonero F, Maschio A, Steri M, Sidore C, Sanna S, Fiorillo E, Bassik MC, Sawcer SJ, Battle A, Novembre J, Jones C, Angius A, Schlessinger D, Cucca F, Montgomery SB, Abecasis GR. Population- and individual-specific regulatory variation in Sardinia. Nat Genet. 2017 May; 49(5):700-707. PMID: 28394350; PMCID: PMC5411016.
      Citations: 22     Fields:    Translation:HumansCells
    43. Koch E, Novembre J. A Temporal Perspective on the Interplay of Demography and Selection on Deleterious Variation in Humans. G3 (Bethesda). 2017 03 10; 7(3):1027-1037. PMID: 28159863; PMCID: PMC5345704.
      Citations: 8     Fields:    Translation:Humans
    44. Marcus JH, Novembre J. Visualizing the geography of genetic variants. Bioinformatics. 2017 02 15; 33(4):594-595. PMID: 27742697; PMCID: PMC5408806.
      Citations: 60     Fields:    Translation:Humans
    45. Novembre J, Peter BM. Recent advances in the study of fine-scale population structure in humans. Curr Opin Genet Dev. 2016 Dec; 41:98-105. PMID: 27662060; PMCID: PMC5291306.
      Citations: 25     Fields:    Translation:Humans
    46. Chiang CW, Ralph P, Novembre J. Conflation of Short Identity-by-Descent Segments Bias Their Inferred Length Distribution. G3 (Bethesda). 2016 05 03; 6(5):1287-96. PMID: 26935417; PMCID: PMC4856080.
      Citations: 21     Fields:    Translation:Humans
    47. Freedman AH, Schweizer RM, Ortega-Del Vecchyo D, Han E, Davis BW, Gronau I, Galaverni M, Fan Z, Marx P, Lorente-Galdos B, Ramirez O, Hormozdiari F, Alkan C, Squire K, Geffen E, Kusak J, Boyko AR, Parker HG, Lee C, Tadigotla V, Siepel A, Bustamante CD, Harkins TT, Nelson SF, Marques-Bonet T, Ostrander EA, Wayne RK, Novembre J, Silva PM, Vilà C. Demographically-Based Evaluation of Genomic Regions under Selection in Domestic Dogs. PLoS Genet. 2016 Mar; 12(3):e1005851. PMID: 26943675; PMCID: PMC4778760.
      Citations: 42     Fields:    Translation:Animals
    48. Petkova D, Novembre J, Stephens M. Visualizing spatial population structure with estimated effective migration surfaces. Nat Genet. 2016 Jan; 48(1):94-100. PMID: 26642242; PMCID: PMC4696895.
      Citations: 174     Fields:    Translation:HumansAnimalsCells
    49. Zoledziewska M, Sidore C, Chiang CWK, Sanna S, Mulas A, Steri M, Busonero F, Marcus JH, Marongiu M, Maschio A, Ortega Del Vecchyo D, Floris M, Meloni A, Delitala A, Concas MP, Murgia F, Biino G, Vaccargiu S, Nagaraja R, Lohmueller KE, UK10K consortium, Timpson NJ, Soranzo N, Tachmazidou I, Dedoussis G, Zeggini E, Understanding Society Scientific Group, Jones C, Lyons R, Angius A, Novembre J, Schlessinger D, Cucca F, Uzzau S, Abecasis GR. Height-reducing variants and selection for short stature in Sardinia. Nat Genet. 2015 Nov; 47(11):1352-1356. PMID: 26366551; PMCID: PMC4627578.
      Citations: 52     Fields:    Translation:Humans
    50. Kessner D, Novembre J. Power analysis of artificial selection experiments using efficient whole genome simulation of quantitative traits. Genetics. 2015 Apr; 199(4):991-1005. PMID: 25672748; PMCID: PMC4391575.
      Citations: 29     Fields:    Translation:Animals
    51. Allentoft ME, Santpere G, Chiang CW, DeGiorgio M, Prado-Martinez J, Rasmussen S, Quilez J, Marigorta UM, Nielsen R, Netea MG, Novembre J, Sturm RA, Sabeti P, Willerslev E, Lalueza-Fox C, Olalde I, Sánchez-Quinto F, Rodríguez JA, Ramírez O, Fernández-Callejo M, Prada ME, Encinas JM, Marquès-Bonet T, Navarro A. Derived immune and ancestral pigmentation alleles in a 7,000-year-old Mesolithic European. Nature. 2014 Mar 13; 507(7491):225-8. PMID: 24463515; PMCID: PMC4269527.
      Citations: 153     Fields:    Translation:Humans
    52. Freedman AH, Gronau I, Schweizer RM, Ortega-Del Vecchyo D, Han E, Galaverni M, Fan Z, Marx P, Lorente-Galdos B, Beale H, Ramirez O, Hormozdiari F, Alkan C, Squire K, Geffen E, Kusak J, Boyko AR, Parker HG, Lee C, Tadigotla V, Wilton A, Siepel A, Bustamante CD, Harkins TT, Nelson SF, Ostrander EA, Wayne RK, Novembre J, Silva PM, Vilà C, Marques-Bonet T. Genome sequencing highlights the dynamic early history of dogs. PLoS Genet. 2014 Jan; 10(1):e1004016. PMID: 24453982; PMCID: PMC3894170.
      Citations: 232     Fields:    Translation:Animals
    53. Kessner D, Novembre J. forqs: forward-in-time simulation of recombination, quantitative traits and selection. Bioinformatics. 2014 Feb 15; 30(4):576-7. PMID: 24336146; PMCID: PMC3928523.
      Citations: 18     Fields:    Translation:Humans
    54. Han E, Sinsheimer JS, Novembre J. Characterizing bias in population genetic inferences from low-coverage sequencing data. Mol Biol Evol. 2014 Mar; 31(3):723-35. PMID: 24288159; PMCID: PMC3935184.
      Citations: 42     Fields:    Translation:HumansCells
    55. Rundel CW, Wunder MB, Alvarado AH, Ruegg KC, Harrigan R, Schuh A, Kelly JF, Siegel RB, DeSante DF, Smith TB, Novembre J. Novel statistical methods for integrating genetic and stable isotope data to infer individual-level migratory connectivity. Mol Ecol. 2013 Aug; 22(16):4163-4176. PMID: 23906339.
      Citations: 16     Fields:    Translation:AnimalsCells
    56. Kessner D, Turner TL, Novembre J. Maximum likelihood estimation of frequencies of known haplotypes from pooled sequence data. Mol Biol Evol. 2013 May; 30(5):1145-58. PMID: 23364324; PMCID: PMC3670732.
      Citations: 33     Fields:    Translation:HumansAnimals
    57. Nelson MR, Wegmann D, Ehm MG, Kessner D, St Jean P, Verzilli C, Shen J, Tang Z, Bacanu SA, Fraser D, Warren L, Aponte J, Zawistowski M, Liu X, Zhang H, Zhang Y, Li J, Li Y, Li L, Woollard P, Topp S, Hall MD, Nangle K, Wang J, Cardon LR, Whittaker JC, Chissoe SL, Novembre J, Mooser V, Abecasis G, Zöllner S. An abundance of rare functional variants in 202 drug target genes sequenced in 14,002 people. Science. 2012 Jul 06; 337(6090):100-4. PMID: 22604722; PMCID: PMC4319976.
      Citations: 367     Fields:    Translation:Humans
    58. Wegmann D, Kessner DE, Veeramah KR, Mathias RA, Nicolae DL, Yanek LR, Sun YV, Torgerson DG, Rafaels N, Mosley T, Becker LC, Ruczinski I, Beaty TH, Kardia SL, Meyers DA, Barnes KC, Becker DM, Freimer NB, Novembre J. Recombination rates in admixed individuals identified by ancestry-based inference. Nat Genet. 2011 Jul 20; 43(9):847-53. PMID: 21775992; PMCID: PMC8582322.
      Citations: 61     Fields:    Translation:Humans
    59. Novembre J, Ramachandran S. Perspectives on human population structure at the cusp of the sequencing era. Annu Rev Genomics Hum Genet. 2011; 12:245-74. PMID: 21801023.
      Citations: 42     Fields:    Translation:Humans
    60. Royal CD, Novembre J, Fullerton SM, Goldstein DB, Long JC, Bamshad MJ, Clark AG. Inferring genetic ancestry: opportunities, challenges, and implications. Am J Hum Genet. 2010 May 14; 86(5):661-73. PMID: 20466090; PMCID: PMC2869013.
      Citations: 94     Fields:    Translation:Humans
    61. Currat M, Ray N, Han E, Excoffier L, Novembre J, François O. Principal component analysis under population genetic models of range expansion and admixture. Mol Biol Evol. 2010 Jun; 27(6):1257-68. PMID: 20097660.
      Citations: 39     Fields:    Translation:Humans
    62. Novembre J, Di Rienzo A. Spatial patterns of variation due to natural selection in humans. Nat Rev Genet. 2009 Nov; 10(11):745-55. PMID: 19823195; PMCID: PMC3989104.
      Citations: 96     Fields:    Translation:HumansAnimals
    63. Alexander DH, Novembre J, Lange K. Fast model-based estimation of ancestry in unrelated individuals. Genome Res. 2009 Sep; 19(9):1655-64. PMID: 19648217; PMCID: PMC2752134.
      Citations: 3750     Fields:    Translation:Humans
    64. Novembre J, Johnson T, Bryc K, Boyko AR, Auton A, Indap A, King KS, Bergmann S, Nelson MR, Stephens M, Bustamante CD, Kutalik Z. Genes mirror geography within Europe. Nature. 2008 Nov 06; 456(7218):98-101. PMID: 18758442; PMCID: PMC2735096.
      Citations: 624     Fields:    Translation:Humans
    65. Novembre J, Stephens M. Interpreting principal component analyses of spatial population genetic variation. Nat Genet. 2008 May; 40(5):646-9. PMID: 18425127; PMCID: PMC3989108.
      Citations: 229     Fields:    Translation:Humans
    66. Novembre J, Galvani AP, Slatkin M. The geographic spread of the CCR5 Delta32 HIV-resistance allele. PLoS Biol. 2005 Nov; 3(11):e339. PMID: 16216086; PMCID: PMC1255740.
      Citations: 78     Fields:    Translation:HumansCells
    67. Novembre JA. Accounting for background nucleotide composition when measuring codon usage bias. Mol Biol Evol. 2002 Aug; 19(8):1390-4. PMID: 12140252.
      Citations: 135     Fields:    Translation:Cells
    Novembre's Networks
    Click the
    Explore
    buttons for more information and interactive visualizations!
    Concepts (209)
    Explore
    _
    Co-Authors (7)
    Explore
    _
    Similar People (60)
    Explore
    _
    Same Department Expand Description
    Explore
    _
    Physical Neighbors
    _