 Cyclic GMP
"Cyclic GMP" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Guanosine cyclic 3',5'-(hydrogen phosphate). A guanine nucleotide containing one phosphate group which is esterified to the sugar moiety in both the 3'- and 5'-positions. It is a cellular regulatory agent and has been described as a second messenger. Its levels increase in response to a variety of hormones, including acetylcholine, insulin, and oxytocin and it has been found to activate specific protein kinases. (From Merck Index, 11th ed)
| Descriptor ID |
D006152
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| MeSH Number(s) |
D03.438.759.646.454.160 D13.695.462.275 D13.695.667.454.160 D13.695.827.426.160
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| Concept/Terms |
Cyclic GMP- Cyclic GMP
- GMP, Cyclic
- Guanosine Cyclic Monophosphate
- Cyclic Monophosphate, Guanosine
- Monophosphate, Guanosine Cyclic
- Guanosine Cyclic 3',5'-Monophosphate
- 3',5'-Monophosphate, Guanosine Cyclic
- Cyclic 3',5'-Monophosphate, Guanosine
- Guanosine Cyclic 3,5 Monophosphate
- Guanosine Cyclic-3',5'-Monophosphate
- Cyclic-3',5'-Monophosphate, Guanosine
- Guanosine Cyclic 3',5' Monophosphate
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Below are MeSH descriptors whose meaning is more general than "Cyclic GMP".
Below are MeSH descriptors whose meaning is more specific than "Cyclic GMP".
This graph shows the total number of publications written about "Cyclic GMP" by people in this website by year, and whether "Cyclic GMP" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1988 | 0 | 1 | 1 | | 1989 | 1 | 1 | 2 | | 1990 | 0 | 2 | 2 | | 1991 | 0 | 1 | 1 | | 1992 | 1 | 0 | 1 | | 1993 | 1 | 2 | 3 | | 1994 | 2 | 0 | 2 | | 1995 | 2 | 2 | 4 | | 1996 | 1 | 1 | 2 | | 1997 | 0 | 3 | 3 | | 1998 | 0 | 3 | 3 | | 1999 | 1 | 3 | 4 | | 2000 | 0 | 2 | 2 | | 2001 | 1 | 0 | 1 | | 2002 | 0 | 3 | 3 | | 2003 | 0 | 1 | 1 | | 2004 | 2 | 0 | 2 | | 2006 | 0 | 1 | 1 | | 2007 | 1 | 0 | 1 | | 2008 | 2 | 0 | 2 | | 2010 | 0 | 1 | 1 | | 2011 | 2 | 2 | 4 | | 2012 | 1 | 1 | 2 | | 2014 | 1 | 4 | 5 |
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Below are the most recent publications written about "Cyclic GMP" by people in Profiles.
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Berne C, Ellison CK, Agarwal R, Severin GB, Fiebig A, Morton RI, Waters CM, Brun YV. Feedback regulation of Caulobacter crescentus holdfast synthesis by flagellum assembly via the holdfast inhibitor HfiA. Mol Microbiol. 2018 10; 110(2):219-238.
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Hong Q, Ma ZC, Huang H, Wang YG, Tan HL, Xiao CR, Liang QD, Zhang HT, Gao Y. Antithrombotic activities of ferulic acid via intracellular cyclic nucleotide signaling. Eur J Pharmacol. 2016 Apr 15; 777:1-8.
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Dasgupta A, Bowman L, D'Arsigny CL, Archer SL. Soluble guanylate cyclase: a new therapeutic target for pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension. Clin Pharmacol Ther. 2015 Jan; 97(1):88-102.
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Wilkins MR, Aldashev AA, Wharton J, Rhodes CJ, Vandrovcova J, Kasperaviciute D, Bhosle SG, Mueller M, Geschka S, Rison S, Kojonazarov B, Morrell NW, Neidhardt I, Surmeli NB, Surmeli NB, Aitman TJ, Stasch JP, Behrends S, Marletta MA. a1-A680T variant in GUCY1A3 as a candidate conferring protection from pulmonary hypertension among Kyrgyz highlanders. Circ Cardiovasc Genet. 2014 Dec; 7(6):920-9.
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Xu Y, Pan J, Sun J, Ding L, Ruan L, Reed M, Yu X, Klabnik J, Lin D, Li J, Chen L, Zhang C, Zhang H, O'Donnell JM. Inhibition of phosphodiesterase 2 reverses impaired cognition and neuronal remodeling caused by chronic stress. Neurobiol Aging. 2015 Feb; 36(2):955-70.
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Iannone L, Zhao L, Dubois O, Duluc L, Rhodes CJ, Wharton J, Wilkins MR, Leiper J, Wojciak-Stothard B. miR-21/DDAH1 pathway regulates pulmonary vascular responses to hypoxia. Biochem J. 2014 Aug 15; 462(1):103-12.
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Liu X, Xie F, Zamah AM, Cao B, Conti M. Multiple pathways mediate luteinizing hormone regulation of cGMP signaling in the mouse ovarian follicle. Biol Reprod. 2014 Jul; 91(1):9.
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Xu Y, Pan J, Chen L, Zhang C, Sun J, Li J, Nguyen L, Nair N, Zhang H, O'Donnell JM. Phosphodiesterase-2 inhibitor reverses corticosterone-induced neurotoxicity and related behavioural changes via cGMP/PKG dependent pathway. Int J Neuropsychopharmacol. 2013 May; 16(4):835-47.
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Farrow KN, Lee KJ, Perez M, Schriewer JM, Wedgwood S, Lakshminrusimha S, Smith CL, Steinhorn RH, Schumacker PT. Brief hyperoxia increases mitochondrial oxidation and increases phosphodiesterase 5 activity in fetal pulmonary artery smooth muscle cells. Antioxid Redox Signal. 2012 Aug 01; 17(3):460-70.
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Rajan S, Torres J, Thompson MS, Philipson LH. SUMO downregulates GLP-1-stimulated cAMP generation and insulin secretion. Am J Physiol Endocrinol Metab. 2012 Mar 15; 302(6):E714-23.
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