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James O'Donnell

TitlePostdoctoral Fellow
InstitutionUniversity of Chicago
DepartmentMedicine
AddressChicago IL 60637
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Liew CW, Xu S, Wang X, McCann M, Whang Kong H, Carley AC, Pang J, Fantuzzi G, O'Donnell JM, Lewandowski ED. Multiphasic Regulation of Systemic and Peripheral Organ Metabolic Responses to Cardiac Hypertrophy. Circ Heart Fail. 2017 Apr; 10(4). PMID: 28404627; PMCID: PMC5466817.
      Citations: 12     Fields:    Translation:AnimalsCells
    2. Subbaiah PV, Dammanahalli KJ, Yang P, Bi J, O'Donnell JM. Enhanced incorporation of dietary DHA into lymph phospholipids by altering its molecular carrier. Biochim Biophys Acta. 2016 Aug; 1861(8 Pt A):723-9. PMID: 27178174; PMCID: PMC4911702.
      Citations: 13     Fields:    Translation:Animals
    3. Tian Y, Gawlak G, O'Donnell JJ, Mambetsariev I, Birukova AA. Modulation of Endothelial Inflammation by Low and High Magnitude Cyclic Stretch. PLoS One. 2016; 11(4):e0153387. PMID: 27128976; PMCID: PMC4851399.
      Citations: 13     Fields:    Translation:HumansCells
    4. Gawlak G, Son S, Tian Y, O'Donnell JJ, Birukov KG, Birukova AA. Chronic high-magnitude cyclic stretch stimulates EC inflammatory response via VEGF receptor 2-dependent mechanism. Am J Physiol Lung Cell Mol Physiol. 2016 06 01; 310(11):L1062-70. PMID: 26993523; PMCID: PMC4935472.
      Citations: 12     Fields:    Translation:HumansCells
    5. Tian Y, Gawlak G, O'Donnell JJ, Birukova AA, Birukov KG. Activation of Vascular Endothelial Growth Factor (VEGF) Receptor 2 Mediates Endothelial Permeability Caused by Cyclic Stretch. J Biol Chem. 2016 May 06; 291(19):10032-45. PMID: 26884340; PMCID: PMC4858957.
      Citations: 38     Fields:    Translation:HumansCells
    6. O'Donnell JM, Fasano MJ, Lewandowski ED. Resolving confounding enrichment kinetics due to overlapping resonance signals from 13C-enriched long chain fatty acid oxidation and uptake within intact hearts. Magn Reson Med. 2015 Aug; 74(2):330-5. PMID: 25199499; PMCID: PMC4362871.
      Citations: 1     Fields:    Translation:AnimalsCells
    7. Xu Y, Pan J, Sun J, Ding L, Ruan L, Reed M, Yu X, Klabnik J, Lin D, Li J, Chen L, Zhang C, Zhang H, O'Donnell JM. Inhibition of phosphodiesterase 2 reverses impaired cognition and neuronal remodeling caused by chronic stress. Neurobiol Aging. 2015 Feb; 36(2):955-70. PMID: 25442113; PMCID: PMC4315741.
      Citations: 44     Fields:    Translation:AnimalsCells
    8. Tian Y, Tian X, Gawlak G, O'Donnell JJ, Sacks DB, Birukova AA. IQGAP1 regulates endothelial barrier function via EB1-cortactin cross talk. Mol Cell Biol. 2014 Sep 15; 34(18):3546-58. PMID: 25022754; PMCID: PMC4135611.
      Citations: 24     Fields:    Translation:HumansCells
    9. Cowan C, Muraleedharan CK, O'Donnell JJ, Singh PK, Lum H, Kumar A, Xu S. MicroRNA-146 inhibits thrombin-induced NF-?B activation and subsequent inflammatory responses in human retinal endothelial cells. Invest Ophthalmol Vis Sci. 2014 Jul 01; 55(8):4944-51. PMID: 24985472.
      Citations: 41     Fields:    Translation:HumansCells
    10. O'Donnell JJ, Birukova AA, Beyer EC, Birukov KG. Gap junction protein connexin43 exacerbates lung vascular permeability. PLoS One. 2014; 9(6):e100931. PMID: 24967639; PMCID: PMC4072707.
      Citations: 40     Fields:    Translation:HumansCells
    11. Gawlak G, Tian Y, O'Donnell JJ, Tian X, Birukova AA, Birukov KG. Paxillin mediates stretch-induced Rho signaling and endothelial permeability via assembly of paxillin-p42/44MAPK-GEF-H1 complex. FASEB J. 2014 Jul; 28(7):3249-60. PMID: 24706358; PMCID: PMC4062829.
      Citations: 21     Fields:    Translation:HumansCells
    12. O'Donnell JT, Marks DH, Danese P, O'Donnell JJ. Drug-induced liver disease: primer for the primary care physician. Dis Mon. 2014 Feb; 60(2):55-104. PMID: 24507900.
      Citations: 6     Fields:    Translation:Humans
    13. Wang ZZ, Zhang Y, Liu YQ, Zhao N, Zhang YZ, Yuan L, An L, Li J, Wang XY, Qin JJ, Wilson SP, O'Donnell JM, Zhang HT, Li YF. RNA interference-mediated phosphodiesterase 4D splice variants knock-down in the prefrontal cortex produces antidepressant-like and cognition-enhancing effects. Br J Pharmacol. 2013 Feb; 168(4):1001-14. PMID: 23003922; PMCID: PMC3631387.
      Citations: 29     Fields:    Translation:HumansAnimalsCells
    14. O'Donnell JM, Kalichira A, Bi J, Lewandowski ED. In vivo, cardiac-specific knockdown of a target protein, malic enzyme-1, in rat via adenoviral delivery of DNA for non-native miRNA. Curr Gene Ther. 2012 Dec; 12(6):454-62. PMID: 22974418; PMCID: PMC3651674.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    15. O'Donnell JJ, O'Donnell JT, Juettner VM. Clinical pharmacology for the primary care physician. Dis Mon. 2012 Oct; 58(10):558-610. PMID: 22999026.
      Citations:    Fields:    Translation:Humans
    16. Xu Y, Pan J, Chen L, Zhang C, Sun J, Li J, Nguyen L, Nair N, Zhang H, O'Donnell JM. Phosphodiesterase-2 inhibitor reverses corticosterone-induced neurotoxicity and related behavioural changes via cGMP/PKG dependent pathway. Int J Neuropsychopharmacol. 2013 May; 16(4):835-47. PMID: 22850435.
      Citations: 28     Fields:    Translation:AnimalsCells
    17. O'Donnell JJ, Zhuge Y, Holian O, Cheng F, Thomas LL, Forsyth CB, Lum H. Loss of p120 catenin upregulates transcription of pro-inflammatory adhesion molecules in human endothelial cells. Microvasc Res. 2011 Sep; 82(2):105-12. PMID: 21554891; PMCID: PMC3149739.
      Citations: 6     Fields:    Translation:HumansCells
    18. Zhang J, O'Donnell JJ, Holian O, Vincent PA, Kim KS, Lum H. P120 catenin represses transcriptional activity through Kaiso in endothelial cells. Microvasc Res. 2010 Sep; 80(2):233-9. PMID: 20382170; PMCID: PMC2917640.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    19. O'Donnell JM, Pound K, Xu X, Lewandowski ED. SERCA1 expression enhances the metabolic efficiency of improved contractility in post-ischemic heart. J Mol Cell Cardiol. 2009 Nov; 47(5):614-21. PMID: 19744494; PMCID: PMC2818126.
      Citations: 11     Fields:    Translation:AnimalsCells
    20. O'Donnell JM, Fields A, Xu X, Chowdhury SA, Geenen DL, Bi J. Limited functional and metabolic improvements in hypertrophic and healthy rat heart overexpressing the skeletal muscle isoform of SERCA1 by adenoviral gene transfer in vivo. Am J Physiol Heart Circ Physiol. 2008 Dec; 295(6):H2483-94. PMID: 18952713; PMCID: PMC2614552.
      Citations: 15     Fields:    Translation:AnimalsCells
    21. Hochart H, Jenkins PV, Preston RJ, Smith OP, White B, O'Donnell J. Concentration-dependent roles for heparin in modifying lipopolysaccharide-induced activation of mononuclear cells in whole blood. Thromb Haemost. 2008 Mar; 99(3):570-5. PMID: 18327406.
      Citations: 14     Fields:    Translation:HumansCells
    22. Hajjhussein H, Suvarna NU, Gremillion C, Chandler LJ, O'Donnell JM. Changes in NMDA receptor-induced cyclic nucleotide synthesis regulate the age-dependent increase in PDE4A expression in primary cortical cultures. Brain Res. 2007 May 29; 1149:58-68. PMID: 17407767; PMCID: PMC2720317.
      Citations: 6     Fields:    Translation:AnimalsCells
    23. Hollestelle MJ, Donkor C, Mantey EA, Chakravorty SJ, Craig A, Akoto AO, O'Donnell J, van Mourik JA, Bunn J. von Willebrand factor propeptide in malaria: evidence of acute endothelial cell activation. Br J Haematol. 2006 Jun; 133(5):562-9. PMID: 16681646.
      Citations: 59     Fields:    Translation:HumansCells
    24. O'Donnell JM, Lewandowski ED. Efficient, cardiac-specific adenoviral gene transfer in rat heart by isolated retrograde perfusion in vivo. Gene Ther. 2005 Jun; 12(12):958-64. PMID: 15789062.
      Citations: 12     Fields:    Translation:AnimalsCells
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