 Lethal Dose 50
"Lethal Dose 50" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The dose amount of poisonous or toxic substance or dose of ionizing radiation required to kill 50% of the tested population.
| Descriptor ID |
D007928
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| MeSH Number(s) |
E05.940.402 G07.690.520
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Lethal Dose 50".
Below are MeSH descriptors whose meaning is more specific than "Lethal Dose 50".
This graph shows the total number of publications written about "Lethal Dose 50" by people in this website by year, and whether "Lethal Dose 50" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1986 | 0 | 1 | 1 | | 1993 | 0 | 1 | 1 | | 2003 | 0 | 1 | 1 | | 2008 | 0 | 1 | 1 | | 2009 | 0 | 2 | 2 | | 2014 | 0 | 1 | 1 |
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Below are the most recent publications written about "Lethal Dose 50" by people in Profiles.
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Guzman ML, Yang N, Sharma KK, Balys M, Corbett CA, Jordan CT, Becker MW, Steidl U, Abdel-Wahab O, Levine RL, Marcucci G, Roboz GJ, Hassane DC. Selective activity of the histone deacetylase inhibitor AR-42 against leukemia stem cells: a novel potential strategy in acute myelogenous leukemia. Mol Cancer Ther. 2014 Aug; 13(8):1979-90.
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Johnson MS, McFarland CA, Bazar MA, Quinn MJ, LaFiandra EM, Talent LG. Toxicity of octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine (HMX) in three vertebrate species. Arch Environ Contam Toxicol. 2010 Apr; 58(3):836-43.
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McFarland CA, Quinn MJ, Bazar MA, Talent LG, Johnson MS. Toxic effects of oral hexahydro-1,3,5-trinitro-1,3,5-triazine in the western fence lizard (Sceloporus occidentalis). Environ Toxicol Chem. 2009 May; 28(5):1043-50.
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Anderson DM, Ciletti NA, Lee-Lewis H, Elli D, Segal J, DeBord KL, Overheim KA, Tretiakova M, Brubaker RR, Schneewind O. Pneumonic plague pathogenesis and immunity in Brown Norway rats. Am J Pathol. 2009 Mar; 174(3):910-21.
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McFarland CA, Quinn MJ, Bazar MA, Remick AK, Talent LG, Johnson MS. Toxicity of oral exposure to 2,4,6-trinitrotoluene in the western fence lizard (Sceloporus occidentalis). Environ Toxicol Chem. 2008 May; 27(5):1102-11.
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Weiss WJ, Lenoy E, Murphy T, Tardio L, Burgio P, Projan SJ, Schneewind O, Alksne L. Effect of srtA and srtB gene expression on the virulence of Staphylococcus aureus in animal models of infection. J Antimicrob Chemother. 2004 Mar; 53(3):480-6.
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Prendergast BJ, Hotchkiss AK, Bilbo SD, Kinsey SG, Nelson RJ. Photoperiodic adjustments in immune function protect Siberian hamsters from lethal endotoxemia. J Biol Rhythms. 2003 Feb; 18(1):51-62.
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Wayte J, Silva AT, Krausz T, Cohen J. Observations on the role of tumor necrosis factor-alpha in a murine model of shock due to Streptococcus pyogenes. Crit Care Med. 1993 Aug; 21(8):1207-12.
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Sigdestad CP, Grdina DJ, Connor AM, Hanson WR. A comparison of radioprotection from three neutron sources and 60Co by WR-2721 and WR-151327. Radiat Res. 1986 May; 106(2):224-33.
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Bosin TR, Campaigne E, Dinner A, Rogers RB, Maickel RP. Comparative toxicological studies of indole, benzo[b] thiophene, and 1-methylindole derivatives. J Toxicol Environ Health. 1976 Jan; 1(3):515-20.
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