"Leucine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An essential branched-chain amino acid important for hemoglobin formation.
| Descriptor ID |
D007930
|
| MeSH Number(s) |
D12.125.070.637 D12.125.142.441
|
| Concept/Terms |
Leucine- Leucine
- L-Leucine
- Leucine, L-Isomer
- L-Isomer Leucine
- Leucine, L Isomer
|
Below are MeSH descriptors whose meaning is more general than "Leucine".
Below are MeSH descriptors whose meaning is more specific than "Leucine".
This graph shows the total number of publications written about "Leucine" by people in this website by year, and whether "Leucine" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 3 | 3 |
| 1996 | 2 | 0 | 2 |
| 1997 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 3 | 3 |
| 2000 | 1 | 1 | 2 |
| 2001 | 1 | 1 | 2 |
| 2003 | 1 | 1 | 2 |
| 2005 | 0 | 2 | 2 |
| 2007 | 0 | 1 | 1 |
| 2009 | 0 | 3 | 3 |
| 2012 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 1 | 1 | 2 |
| 2020 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Leucine" by people in Profiles.
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Iron drives anabolic metabolism through active histone demethylation and mTORC1. Nat Cell Biol. 2023 Oct; 25(10):1478-1494.
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High expression of maternal embryonic leucine-zipper kinase (MELK) impacts clinical outcomes in patients with ovarian cancer and its inhibition suppresses ovarian cancer cells growth ex vivo. J Gynecol Oncol. 2020 Nov; 31(6):e93.
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Serum amino acid concentrations and clinical outcomes in smokers: SPIROMICS metabolomics study. Sci Rep. 2019 08 06; 9(1):11367.
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Randomized Controlled Trial of a Leucine-Metformin-Sildenafil Combination (NS-0200) on Weight and Metabolic Parameters. Obesity (Silver Spring). 2019 01; 27(1):59-67.
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Randomised clinical trial: a leucine-metformin-sildenafil combination (NS-0200) vs placebo in patients with non-alcoholic fatty liver disease. Aliment Pharmacol Ther. 2018 06; 47(12):1639-1651.
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Different Roles of N-Terminal and C-Terminal Domains in Calmodulin for Activation of Bacillus anthracis Edema Factor. Toxins (Basel). 2015 Jul 13; 7(7):2598-614.
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Exploring the conformational transitions of biomolecular systems using a simple two-state anisotropic network model. PLoS Comput Biol. 2014 Apr; 10(4):e1003521.
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Pharmaconutrition review: physiological mechanisms. JPEN J Parenter Enteral Nutr. 2013 Sep; 37(5 Suppl):51S-65S.
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Nampt secreted from cardiomyocytes promotes development of cardiac hypertrophy and adverse ventricular remodeling. Am J Physiol Heart Circ Physiol. 2013 Feb 01; 304(3):H415-26.
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Autosomal-dominant retinitis pigmentosa caused by a mutation in SNRNP200, a gene required for unwinding of U4/U6 snRNAs. Am J Hum Genet. 2009 Nov; 85(5):617-27.