 Muscimol
"Muscimol" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A neurotoxic isoxazole isolated from species of AMANITA. It is obtained by decarboxylation of IBOTENIC ACID. Muscimol is a potent agonist of GABA-A RECEPTORS and is used mainly as an experimental tool in animal and tissue studies.
| Descriptor ID |
D009118
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| MeSH Number(s) |
D03.383.129.462.470 D23.946.587.587
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Muscimol".
Below are MeSH descriptors whose meaning is more specific than "Muscimol".
This graph shows the total number of publications written about "Muscimol" by people in this website by year, and whether "Muscimol" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1985 | 0 | 1 | 1 | | 1986 | 0 | 1 | 1 | | 1998 | 1 | 1 | 2 | | 1999 | 0 | 1 | 1 | | 2000 | 0 | 2 | 2 | | 2002 | 0 | 1 | 1 | | 2004 | 0 | 1 | 1 | | 2005 | 0 | 1 | 1 | | 2006 | 0 | 1 | 1 | | 2010 | 0 | 1 | 1 |
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Below are the most recent publications written about "Muscimol" by people in Profiles.
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Neugebauer NM, Miyauchi M, Sato T, Tadano J, Akal H, Ardehali H, Meltzer HY. Hippocampal GABAA antagonism reverses the novel object recognition deficit in sub-chronic phencyclidine-treated rats. Behav Brain Res. 2018 04 16; 342:11-18.
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Wei W, Hamby AM, Zhou K, Feller MB. Development of asymmetric inhibition underlying direction selectivity in the retina. Nature. 2011 Jan 20; 469(7330):402-6.
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Brink TS, Hellman KM, Lambert AM, Mason P. Raphe magnus neurons help protect reactions to visceral pain from interruption by cutaneous pain. J Neurophysiol. 2006 Dec; 96(6):3423-32.
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Mehaffey WH, Doiron B, Maler L, Turner RW. Deterministic multiplicative gain control with active dendrites. J Neurosci. 2005 Oct 26; 25(43):9968-77.
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Yuan CS, Mehendale S, Xiao Y, Aung HH, Xie JT, Ang-Lee MK. The gamma-aminobutyric acidergic effects of valerian and valerenic acid on rat brainstem neuronal activity. Anesth Analg. 2004 Feb; 98(2):353-8, table of contents.
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Yuan CS, Dey L, Wang A, Mehendale S, Xie JT, Aung HH, Ang-Lee MK. Kavalactones and dihydrokavain modulate GABAergic activity in a rat gastric-brainstem preparation. Planta Med. 2002 Dec; 68(12):1092-6.
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Hu JH, He XB, Wu Q, Yan YC, Koide SS. Subunit composition and function of GABAA receptors of rat spermatozoa. Neurochem Res. 2002 Mar; 27(3):195-9.
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Belton T, McCrea RA. Role of the cerebellar flocculus region in the coordination of eye and head movements during gaze pursuit. J Neurophysiol. 2000 Sep; 84(3):1614-26.
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Belton T, McCrea RA. Role of the cerebellar flocculus region in cancellation of the VOR during passive whole body rotation. J Neurophysiol. 2000 Sep; 84(3):1599-613.
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Belton T, McCrea RA. Contribution of the cerebellar flocculus to gaze control during active head movements. J Neurophysiol. 1999 Jun; 81(6):3105-9.
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