"Muscimol" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A neurotoxic isoxazole isolated from species of AMANITA. It is obtained by decarboxylation of IBOTENIC ACID. Muscimol is a potent agonist of GABA-A RECEPTORS and is used mainly as an experimental tool in animal and tissue studies.
Descriptor ID |
D009118
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MeSH Number(s) |
D03.383.129.462.470 D23.946.587.587
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Muscimol".
Below are MeSH descriptors whose meaning is more specific than "Muscimol".
This graph shows the total number of publications written about "Muscimol" by people in this website by year, and whether "Muscimol" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1998 | 1 | 1 | 2 |
1999 | 0 | 1 | 1 |
2000 | 0 | 2 | 2 |
2002 | 0 | 1 | 1 |
2003 | 1 | 0 | 1 |
2004 | 0 | 1 | 1 |
2005 | 0 | 1 | 1 |
2006 | 0 | 1 | 1 |
2010 | 0 | 2 | 2 |
2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Muscimol" by people in Profiles.
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Primate superior colliculus is causally engaged in abstract higher-order cognition. Nat Neurosci. 2024 Oct; 27(10):1999-2008.
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Hippocampal GABAA antagonism reverses the novel object recognition deficit in sub-chronic phencyclidine-treated rats. Behav Brain Res. 2018 04 16; 342:11-18.
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Development of asymmetric inhibition underlying direction selectivity in the retina. Nature. 2011 Jan 20; 469(7330):402-6.
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Behavioral characteristics and neural mechanisms mediating performance in a rodent version of the Balloon Analog Risk Task. Neuropsychopharmacology. 2010 Jul; 35(8):1797-806.
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Raphe magnus neurons help protect reactions to visceral pain from interruption by cutaneous pain. J Neurophysiol. 2006 Dec; 96(6):3423-32.
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Deterministic multiplicative gain control with active dendrites. J Neurosci. 2005 Oct 26; 25(43):9968-77.
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The gamma-aminobutyric acidergic effects of valerian and valerenic acid on rat brainstem neuronal activity. Anesth Analg. 2004 Feb; 98(2):353-358.
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Increases in food intake or food-seeking behavior induced by GABAergic, opioid, or dopaminergic stimulation of the nucleus accumbens: is it hunger? Psychopharmacology (Berl). 2004 Mar; 172(3):241-7.
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Kavalactones and dihydrokavain modulate GABAergic activity in a rat gastric-brainstem preparation. Planta Med. 2002 Dec; 68(12):1092-6.
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Subunit composition and function of GABAA receptors of rat spermatozoa. Neurochem Res. 2002 Mar; 27(3):195-9.