 Ketamine
"Ketamine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
| Descriptor ID |
D007649
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| MeSH Number(s) |
D02.455.426.392.368.367.652
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| Concept/Terms |
Ketamine- Ketamine
- 2-(2-Chlorophenyl)-2-(methylamino)cyclohexanone
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Below are MeSH descriptors whose meaning is more general than "Ketamine".
Below are MeSH descriptors whose meaning is more specific than "Ketamine".
This graph shows the total number of publications written about "Ketamine" by people in this website by year, and whether "Ketamine" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1983 | 1 | 0 | 1 | | 1995 | 0 | 1 | 1 | | 1997 | 0 | 2 | 2 | | 1999 | 0 | 2 | 2 | | 2005 | 1 | 1 | 2 | | 2008 | 3 | 1 | 4 | | 2009 | 1 | 1 | 2 | | 2011 | 1 | 0 | 1 | | 2012 | 1 | 0 | 1 | | 2013 | 1 | 1 | 2 | | 2016 | 1 | 0 | 1 | | 2018 | 1 | 0 | 1 | | 2020 | 3 | 0 | 3 | | 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Ketamine" by people in Profiles.
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Murphy GS, Avram MJ, Greenberg SB, Benson J, Bilimoria S, Maher CE, Teister K, Szokol JW. Perioperative Methadone and Ketamine for Postoperative Pain Control in Spinal Surgical Patients: A Randomized, Double-blind, Placebo-controlled Trial. Anesthesiology. 2021 05 01; 134(5):697-708.
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Mehta SD, Smyth D, Vasilopoulos T, Friedman J, Sappenfield JW, Alex G. Ketamine infusion reduces narcotic requirements following gastric bypass surgery: a randomized controlled trial. Surg Obes Relat Dis. 2021 Apr; 17(4):737-743.
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Kalmoe MC, Janski AM, Zorumski CF, Nagele P, Palanca BJ, Conway CR. Ketamine and nitrous oxide: The evolution of NMDA receptor antagonists as antidepressant agents. J Neurol Sci. 2020 05 15; 412:116778.
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Grant JE, Chamberlain SR. Response of Refractory Gambling Disorder to Intravenous Ketamine. Prim Care Companion CNS Disord. 2020 01 16; 22(1).
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Wray NH, Schappi JM, Singh H, Senese NB, Rasenick MM. NMDAR-independent, cAMP-dependent antidepressant actions of ketamine. Mol Psychiatry. 2019 12; 24(12):1833-1843.
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Gad PN, Salyards GW, Garzel LM, Christe KL, Edgerton VR, Havton LA. Generalized convulsive seizures are associated with ketamine anesthesia in a rhesus macaque (Macaca mulatta) undergoing urodynamic studies and transcutaneous spinal cord stimulation. J Med Primatol. 2017 12; 46(6):359-363.
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Clinical Policy: Critical Issues in the Diagnosis and Management of the Adult Psychiatric Patient in the Emergency Department. Ann Emerg Med. 2017 Apr; 69(4):480-498.
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Rabi J, Minori J, Abad H, Lee R, Gittler M. Topical Ketamine 10% for Neuropathic Pain in Spinal Cord Injury Patients: An Open-Label Trial. Int J Pharm Compd. 2016 Nov-Dec; 20(6):517-520.
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Sabharwal V, Ramsay E, Martinez R, Shumate R, Khan F, Dave H, Iwuchukwu I, McGrade H. Propofol-ketamine combination therapy for effective control of super-refractory status epilepticus. Epilepsy Behav. 2015 Nov; 52(Pt A):264-6.
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Heilbrunn BR, Chang TP, Liu DR. A retrospective comparison of ketamine dosing regimens for pediatric procedural sedation. Eur J Emerg Med. 2015 Apr; 22(2):111-6.
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