 Nitric Oxide
"Nitric Oxide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A free radical gas produced endogenously by a variety of mammalian cells, synthesized from ARGININE by NITRIC OXIDE SYNTHASE. Nitric oxide is one of the ENDOTHELIUM-DEPENDENT RELAXING FACTORS released by the vascular endothelium and mediates VASODILATION. It also inhibits platelet aggregation, induces disaggregation of aggregated platelets, and inhibits platelet adhesion to the vascular endothelium. Nitric oxide activates cytosolic GUANYLATE CYCLASE and thus elevates intracellular levels of CYCLIC GMP.
| Descriptor ID |
D009569
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| MeSH Number(s) |
D01.339.387 D01.625.550.500 D01.625.700.500 D01.650.550.587.600
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| Concept/Terms |
Nitric Oxide- Nitric Oxide
- Oxide, Nitric
- Mononitrogen Monoxide
- Monoxide, Mononitrogen
- Nitrogen Monoxide
- Monoxide, Nitrogen
- Endogenous Nitrate Vasodilator
- Nitrate Vasodilator, Endogenous
- Vasodilator, Endogenous Nitrate
- Nitric Oxide, Endothelium-Derived
- Endothelium-Derived Nitric Oxide
- Nitric Oxide, Endothelium Derived
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Below are MeSH descriptors whose meaning is more general than "Nitric Oxide".
Below are MeSH descriptors whose meaning is more specific than "Nitric Oxide".
This graph shows the total number of publications written about "Nitric Oxide" by people in this website by year, and whether "Nitric Oxide" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1989 | 2 | 1 | 3 | | 1990 | 3 | 0 | 3 | | 1991 | 1 | 0 | 1 | | 1992 | 3 | 0 | 3 | | 1993 | 8 | 0 | 8 | | 1994 | 6 | 2 | 8 | | 1995 | 8 | 1 | 9 | | 1996 | 9 | 5 | 14 | | 1997 | 8 | 0 | 8 | | 1998 | 5 | 4 | 9 | | 1999 | 10 | 1 | 11 | | 2000 | 6 | 6 | 12 | | 2001 | 5 | 1 | 6 | | 2002 | 8 | 3 | 11 | | 2003 | 6 | 3 | 9 | | 2004 | 3 | 2 | 5 | | 2005 | 2 | 5 | 7 | | 2006 | 2 | 6 | 8 | | 2007 | 3 | 3 | 6 | | 2008 | 4 | 3 | 7 | | 2009 | 3 | 4 | 7 | | 2010 | 7 | 3 | 10 | | 2011 | 2 | 9 | 11 | | 2012 | 5 | 4 | 9 | | 2013 | 3 | 2 | 5 | | 2014 | 2 | 7 | 9 | | 2015 | 2 | 2 | 4 | | 2016 | 0 | 3 | 3 | | 2017 | 1 | 6 | 7 | | 2018 | 1 | 6 | 7 | | 2019 | 0 | 1 | 1 | | 2020 | 1 | 1 | 2 |
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Below are the most recent publications written about "Nitric Oxide" by people in Profiles.
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Jani MS, Zou J, Veetil AT, Krishnan Y. A DNA-based fluorescent probe maps NOS3 activity with subcellular spatial resolution. Nat Chem Biol. 2020 06; 16(6):660-666.
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Dick BP, McMahan R, Knowles T, Becker L, Gharib SA, Vaisar T, Wietecha T, O'Brien KD, Bornfeldt KE, Chait A, Kim F. Hematopoietic Cell-Expressed Endothelial Nitric Oxide Protects the Liver From Insulin Resistance. Arterioscler Thromb Vasc Biol. 2020 03; 40(3):670-681.
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Kim SY, Lee MS, Chang E, Jung S, Ko H, Lee E, Lee S, Kim CT, Kim IH, Kim Y. Tartary Buckwheat Extract Attenuated the Obesity-Induced Inflammation and Increased Muscle PGC-1a/SIRT1 Expression in High Fat Diet-Induced Obese Rats. Nutrients. 2019 Mar 18; 11(3).
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Cremasco V, Astarita JL, Grauel AL, Keerthivasan S, MacIsaac K, Woodruff MC, Wu M, Spel L, Santoro S, Amoozgar Z, Laszewski T, Migoni SC, Knoblich K, Fletcher AL, LaFleur M, Wucherpfennig KW, Pure E, Dranoff G, Carroll MC, Turley SJ. FAP Delineates Heterogeneous and Functionally Divergent Stromal Cells in Immune-Excluded Breast Tumors. Cancer Immunol Res. 2018 12; 6(12):1472-1485.
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Suzuki S, Togari H, Potenziano JL, Schreiber MD. Efficacy of inhaled nitric oxide in neonates with hypoxic respiratory failure and pulmonary hypertension: the Japanese experience. J Perinat Med. 2018 Aug 28; 46(6):657-663.
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Torgerson DG, Ballard PL, Keller RL, Oh SS, Huntsman S, Hu D, Eng C, Burchard EG, Ballard RA. Ancestry and genetic associations with bronchopulmonary dysplasia in preterm infants. . 2018 11 01; 315(5):L858-L869.
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Ballard RA, Ballard PL, Askie LM, Schreiber MD, Hibbs AM, Torgerson DG, Keller RL. Reply. J Pediatr. 2018 10; 201:300-301.
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Veetil AT, Jani MS, Krishnan Y. Chemical control over membrane-initiated steroid signaling with a DNA nanocapsule. Proc Natl Acad Sci U S A. 2018 09 18; 115(38):9432-9437.
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Fancher IS, Ahn SJ, Adamos C, Osborn C, Oh MJ, Fang Y, Reardon CA, Getz GS, Phillips SA, Levitan I. Hypercholesterolemia-Induced Loss of Flow-Induced Vasodilation and Lesion Formation in Apolipoprotein E-Deficient Mice Critically Depend on Inwardly Rectifying K+ Channels. J Am Heart Assoc. 2018 03 03; 7(5).
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Hiroi Y, Noma K, Kim HH, Sladojevic N, Tabit CE, Li Y, Soydan G, Salomone S, Moskowitz MA, Liao JK. Neuroprotection Mediated by Upregulation of Endothelial Nitric Oxide Synthase in Rho-Associated, Coiled-Coil-Containing Kinase 2 Deficient Mice. Circ J. 2018 03 23; 82(4):1195-1204.
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