"Nitric Oxide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A free radical gas produced endogenously by a variety of mammalian cells, synthesized from ARGININE by NITRIC OXIDE SYNTHASE. Nitric oxide is one of the ENDOTHELIUM-DEPENDENT RELAXING FACTORS released by the vascular endothelium and mediates VASODILATION. It also inhibits platelet aggregation, induces disaggregation of aggregated platelets, and inhibits platelet adhesion to the vascular endothelium. Nitric oxide activates cytosolic GUANYLATE CYCLASE and thus elevates intracellular levels of CYCLIC GMP.
| Descriptor ID |
D009569
|
| MeSH Number(s) |
D01.339.387 D01.625.550.500 D01.625.700.500 D01.650.550.587.600
|
| Concept/Terms |
Nitric Oxide- Nitric Oxide
- Oxide, Nitric
- Nitrogen Monoxide
- Monoxide, Nitrogen
- Nitric Oxide, Endothelium-Derived
- Endothelium-Derived Nitric Oxide
- Nitric Oxide, Endothelium Derived
- Endogenous Nitrate Vasodilator
- Nitrate Vasodilator, Endogenous
- Vasodilator, Endogenous Nitrate
- Mononitrogen Monoxide
- Monoxide, Mononitrogen
|
Below are MeSH descriptors whose meaning is more general than "Nitric Oxide".
Below are MeSH descriptors whose meaning is more specific than "Nitric Oxide".
This graph shows the total number of publications written about "Nitric Oxide" by people in this website by year, and whether "Nitric Oxide" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 8 | 1 | 9 |
| 1996 | 9 | 4 | 13 |
| 1997 | 8 | 0 | 8 |
| 1998 | 6 | 3 | 9 |
| 1999 | 9 | 1 | 10 |
| 2000 | 6 | 7 | 13 |
| 2001 | 5 | 1 | 6 |
| 2002 | 7 | 3 | 10 |
| 2003 | 6 | 6 | 12 |
| 2004 | 4 | 3 | 7 |
| 2005 | 2 | 5 | 7 |
| 2006 | 3 | 7 | 10 |
| 2007 | 3 | 3 | 6 |
| 2008 | 3 | 3 | 6 |
| 2009 | 3 | 4 | 7 |
| 2010 | 8 | 5 | 13 |
| 2011 | 2 | 9 | 11 |
| 2012 | 4 | 5 | 9 |
| 2013 | 4 | 3 | 7 |
| 2014 | 2 | 7 | 9 |
| 2015 | 2 | 2 | 4 |
| 2016 | 0 | 4 | 4 |
| 2017 | 2 | 5 | 7 |
| 2018 | 1 | 6 | 7 |
| 2019 | 0 | 1 | 1 |
| 2020 | 2 | 1 | 3 |
| 2021 | 0 | 2 | 2 |
| 2022 | 2 | 1 | 3 |
| 2023 | 2 | 1 | 3 |
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Below are the most recent publications written about "Nitric Oxide" by people in Profiles.
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Association of Sputum Eosinophilia With Easily Measured Type-2 Inflammatory Biomarkers in Untreated Mild Persistent Asthma. J Allergy Clin Immunol Pract. 2024 04; 12(4):960-969.e6.
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Sub-1.4 cm3 capsule for detecting labile inflammatory biomarkers in situ. Nature. 2023 Aug; 620(7973):386-392.
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Non-viral nitric oxide-based gene therapy improves perfusion and liposomal doxorubicin sonopermeation in neuroblastoma models. Theranostics. 2023; 13(10):3402-3418.
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Microbial biofilms: An ecological tale of Jekyll and Hyde. Curr Biol. 2022 12 19; 32(24):R1349-R1351.
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Pulmonary Procedures During the COVID-19 Pandemic: A Work Group Report of the AAAAI Asthma Diagnosis and Treatment (ADT) Interest Section. J Allergy Clin Immunol Pract. 2022 06; 10(6):1474-1484.
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Inhaled Nitric Oxide for Fibrotic Interstitial Lung Disease: A Step Forward. Ann Am Thorac Soc. 2022 04; 19(4):536-538.
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Toll-like receptor-7/8 agonist kill Leishmania amazonensis by acting as pro-oxidant and pro-inflammatory agent. J Pharm Pharmacol. 2021 Aug 12; 73(9):1180-1190.
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Astrocytes propel neurovascular dysfunction during cerebral cavernous malformation lesion formation. J Clin Invest. 2021 07 01; 131(13).
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Efficacy of Nitric Oxide Administration in Attenuating Ischemia/Reperfusion Injury During Neonatal Cardiopulmonary Bypass. World J Pediatr Congenit Heart Surg. 2020 07; 11(4):417-423.
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A DNA-based fluorescent probe maps NOS3 activity with subcellular spatial resolution. Nat Chem Biol. 2020 06; 16(6):660-666.