 Nitric Oxide
"Nitric Oxide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A free radical gas produced endogenously by a variety of mammalian cells, synthesized from ARGININE by NITRIC OXIDE SYNTHASE. Nitric oxide is one of the ENDOTHELIUM-DEPENDENT RELAXING FACTORS released by the vascular endothelium and mediates VASODILATION. It also inhibits platelet aggregation, induces disaggregation of aggregated platelets, and inhibits platelet adhesion to the vascular endothelium. Nitric oxide activates cytosolic GUANYLATE CYCLASE and thus elevates intracellular levels of CYCLIC GMP.
| Descriptor ID |
D009569
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| MeSH Number(s) |
D01.339.387 D01.625.550.500 D01.625.700.500 D01.650.550.587.600
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| Concept/Terms |
Nitric Oxide- Nitric Oxide
- Oxide, Nitric
- Mononitrogen Monoxide
- Monoxide, Mononitrogen
- Nitrogen Monoxide
- Monoxide, Nitrogen
- Endogenous Nitrate Vasodilator
- Nitrate Vasodilator, Endogenous
- Vasodilator, Endogenous Nitrate
- Nitric Oxide, Endothelium-Derived
- Endothelium-Derived Nitric Oxide
- Nitric Oxide, Endothelium Derived
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Below are MeSH descriptors whose meaning is more general than "Nitric Oxide".
Below are MeSH descriptors whose meaning is more specific than "Nitric Oxide".
This graph shows the total number of publications written about "Nitric Oxide" by people in this website by year, and whether "Nitric Oxide" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1989 | 2 | 0 | 2 | | 1990 | 2 | 0 | 2 | | 1991 | 1 | 0 | 1 | | 1992 | 3 | 0 | 3 | | 1993 | 8 | 0 | 8 | | 1994 | 6 | 2 | 8 | | 1995 | 8 | 1 | 9 | | 1996 | 8 | 4 | 12 | | 1997 | 8 | 0 | 8 | | 1998 | 6 | 4 | 10 | | 1999 | 9 | 1 | 10 | | 2000 | 6 | 7 | 13 | | 2001 | 4 | 1 | 5 | | 2002 | 8 | 3 | 11 | | 2003 | 6 | 5 | 11 | | 2004 | 4 | 2 | 6 | | 2005 | 1 | 4 | 5 | | 2006 | 2 | 6 | 8 | | 2007 | 3 | 2 | 5 | | 2008 | 3 | 3 | 6 | | 2009 | 2 | 4 | 6 | | 2010 | 5 | 4 | 9 | | 2011 | 1 | 8 | 9 | | 2012 | 5 | 4 | 9 | | 2013 | 3 | 2 | 5 | | 2014 | 2 | 6 | 8 | | 2015 | 2 | 2 | 4 | | 2016 | 0 | 4 | 4 | | 2017 | 1 | 6 | 7 | | 2018 | 1 | 6 | 7 | | 2019 | 0 | 1 | 1 | | 2020 | 2 | 1 | 3 | | 2021 | 0 | 1 | 1 | | 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Nitric Oxide" by people in Profiles.
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Khor YH, Adegunsoye A. Inhaled Nitric Oxide for Fibrotic Interstitial Lung Disease: A Step Forward. Ann Am Thorac Soc. 2022 04; 19(4):536-538.
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Lopez-Ramirez MA, Lai CC, Soliman SI, Hale P, Pham A, Estrada EJ, McCurdy S, Girard R, Verma R, Moore T, Lightle R, Hobson N, Shenkar R, Poulsen O, Haddad GG, Daneman R, Gongol B, Sun H, Lagarrigue F, Awad IA, Ginsberg MH. Astrocytes propel neurovascular dysfunction during cerebral cavernous malformation lesion formation. J Clin Invest. 2021 07 01; 131(13).
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Elzein C, Urbas C, Hughes B, Li Y, Lefaiver C, Ilbawi M, Vricella L. Efficacy of Nitric Oxide Administration in Attenuating Ischemia/Reperfusion Injury During Neonatal Cardiopulmonary Bypass. World J Pediatr Congenit Heart Surg. 2020 07; 11(4):417-423.
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Jani MS, Zou J, Veetil AT, Krishnan Y. A DNA-based fluorescent probe maps NOS3 activity with subcellular spatial resolution. Nat Chem Biol. 2020 06; 16(6):660-666.
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Dick BP, McMahan R, Knowles T, Becker L, Gharib SA, Vaisar T, Wietecha T, O'Brien KD, Bornfeldt KE, Chait A, Kim F. Hematopoietic Cell-Expressed Endothelial Nitric Oxide Protects the Liver From Insulin Resistance. Arterioscler Thromb Vasc Biol. 2020 03; 40(3):670-681.
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Kim SY, Lee MS, Chang E, Jung S, Ko H, Lee E, Lee S, Kim CT, Kim IH, Kim Y. Tartary Buckwheat Extract Attenuated the Obesity-Induced Inflammation and Increased Muscle PGC-1a/SIRT1 Expression in High Fat Diet-Induced Obese Rats. Nutrients. 2019 Mar 18; 11(3).
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Cremasco V, Astarita JL, Grauel AL, Keerthivasan S, MacIsaac K, Woodruff MC, Wu M, Spel L, Santoro S, Amoozgar Z, Laszewski T, Migoni SC, Knoblich K, Fletcher AL, LaFleur M, Wucherpfennig KW, Pure E, Dranoff G, Carroll MC, Turley SJ. FAP Delineates Heterogeneous and Functionally Divergent Stromal Cells in Immune-Excluded Breast Tumors. Cancer Immunol Res. 2018 12; 6(12):1472-1485.
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Suzuki S, Togari H, Potenziano JL, Schreiber MD. Efficacy of inhaled nitric oxide in neonates with hypoxic respiratory failure and pulmonary hypertension: the Japanese experience. J Perinat Med. 2018 Aug 28; 46(6):657-663.
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Torgerson DG, Ballard PL, Keller RL, Oh SS, Huntsman S, Hu D, Eng C, Burchard EG, Ballard RA. Ancestry and genetic associations with bronchopulmonary dysplasia in preterm infants. Am J Physiol Lung Cell Mol Physiol. 2018 11 01; 315(5):L858-L869.
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Ballard RA, Ballard PL, Askie LM, Schreiber MD, Hibbs AM, Torgerson DG, Keller RL. Reply. J Pediatr. 2018 10; 201:300-301.
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