 Ligands
"Ligands" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A molecule that binds to another molecule, used especially to refer to a small molecule that binds specifically to a larger molecule, e.g., an antigen binding to an antibody, a hormone or neurotransmitter binding to a receptor, or a substrate or allosteric effector binding to an enzyme. Ligands are also molecules that donate or accept a pair of electrons to form a coordinate covalent bond with the central metal atom of a coordination complex. (From Dorland, 27th ed)
| Descriptor ID |
D008024
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| MeSH Number(s) |
D27.720.470.480
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Ligands".
Below are MeSH descriptors whose meaning is more specific than "Ligands".
This graph shows the total number of publications written about "Ligands" by people in this website by year, and whether "Ligands" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1984 | 0 | 1 | 1 | | 1986 | 0 | 1 | 1 | | 1987 | 0 | 1 | 1 | | 1988 | 0 | 2 | 2 | | 1989 | 0 | 2 | 2 | | 1990 | 0 | 1 | 1 | | 1993 | 0 | 1 | 1 | | 1994 | 0 | 4 | 4 | | 1995 | 0 | 4 | 4 | | 1996 | 0 | 6 | 6 | | 1997 | 0 | 8 | 8 | | 1998 | 1 | 6 | 7 | | 1999 | 0 | 7 | 7 | | 2000 | 0 | 8 | 8 | | 2001 | 0 | 10 | 10 | | 2002 | 0 | 16 | 16 | | 2003 | 0 | 21 | 21 | | 2004 | 0 | 13 | 13 | | 2005 | 2 | 15 | 17 | | 2006 | 0 | 13 | 13 | | 2007 | 0 | 17 | 17 | | 2008 | 0 | 12 | 12 | | 2009 | 1 | 20 | 21 | | 2010 | 1 | 9 | 10 | | 2011 | 0 | 8 | 8 | | 2012 | 2 | 15 | 17 | | 2013 | 0 | 11 | 11 | | 2014 | 0 | 12 | 12 | | 2015 | 0 | 13 | 13 | | 2016 | 0 | 12 | 12 | | 2017 | 1 | 10 | 11 | | 2018 | 0 | 12 | 12 | | 2019 | 0 | 8 | 8 | | 2020 | 1 | 16 | 17 | | 2021 | 0 | 8 | 8 | | 2022 | 0 | 9 | 9 |
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Below are the most recent publications written about "Ligands" by people in Profiles.
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Konstantinopoulos PA, Gockley AA, Xiong N, Krasner C, Horowitz N, Campos S, Wright AA, Liu JF, Shea M, Yeku O, Castro C, Polak M, Lee EK, Sawyer H, Bowes B, Moroney J, Cheng SC, Tayob N, Bouberhan S, Spriggs D, Penson RT, Fleming GF, Nucci MR, Matulonis UA. Evaluation of Treatment With Talazoparib and Avelumab in Patients With Recurrent Mismatch Repair Proficient Endometrial Cancer. JAMA Oncol. 2022 09 01; 8(9):1317-1322.
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Medina KL. Flt3 Signaling in B Lymphocyte Development and Humoral Immunity. Int J Mol Sci. 2022 Jun 30; 23(13).
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Rees HC, Gogacz W, Li NS, Koirala D, Piccirilli JA. Structural Basis for Fluorescence Activation by Pepper RNA. ACS Chem Biol. 2022 07 15; 17(7):1866-1875.
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Pandey SP, Bender MJ, McPherson AC, Phelps CM, Sanchez LM, Rana M, Hedden L, Sangani KA, Chen L, Shapira JH, Siller M, Goel C, Verdú EF, Jabri B, Chang A, Chandran UR, Mullett SJ, Wendell SG, Singhi AD, Tilstra JS, Pierre JF, Arteel GE, Hinterleitner R, Meisel M. Tet2 deficiency drives liver microbiome dysbiosis triggering Tc1 cell autoimmune hepatitis. Cell Host Microbe. 2022 07 13; 30(7):1003-1019.e10.
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Shao J, Gao L, Leung ML, Gallinger B, Inglese C, Meyn MS, Del Gaudio D, Das S, Li Z. Exome sequencing identifies PD-L2 as a potential predisposition gene for lymphoma. Hematol Oncol. 2022 Aug; 40(3):475-478.
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Hosfield DJ, Weber S, Li NS, Sauvage M, Joiner CF, Hancock GR, Sullivan EA, Ndukwe E, Han R, Cush S, Lainé M, Mader SC, Greene GL, Fanning SW. Stereospecific lasofoxifene derivatives reveal the interplay between estrogen receptor alpha stability and antagonistic activity in ESR1 mutant breast cancer cells. Elife. 2022 05 16; 11.
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Liu D, Thélot FA, Piccirilli JA, Liao M, Yin P. Sub-3-Å cryo-EM structure of RNA enabled by engineered homomeric self-assembly. Nat Methods. 2022 05; 19(5):576-585.
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Tseng YY, Sanders MA, Zhang H, Zhou L, Chou CY, Granneman JG. Structural and functional insights into ABHD5, a ligand-regulated lipase co-activator. Sci Rep. 2022 02 16; 12(1):2565.
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Batchu S, Hakim A, Henry OS, Madzo J, Atabek U, Spitz FR, Hong YK. Transcriptome-guided resolution of tumor microenvironment interactions in pheochromocytoma and paraganglioma subtypes. J Endocrinol Invest. 2022 May; 45(5):989-998.
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Wang J, Liu K, Xiao T, Liu P, Prinz RA, Xu X. Uric acid accumulation in DNA-damaged tumor cells induces NKG2D ligand expression and antitumor immunity by activating TGF-ß-activated kinase 1. Oncoimmunology. 2022; 11(1):2016159.
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