"Ligands" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A molecule that binds to another molecule, used especially to refer to a small molecule that binds specifically to a larger molecule, e.g., an antigen binding to an antibody, a hormone or neurotransmitter binding to a receptor, or a substrate or allosteric effector binding to an enzyme. Ligands are also molecules that donate or accept a pair of electrons to form a coordinate covalent bond with the central metal atom of a coordination complex. (From Dorland, 27th ed)
| Descriptor ID |
D008024
|
| MeSH Number(s) |
D27.720.470.480
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Ligands".
Below are MeSH descriptors whose meaning is more specific than "Ligands".
This graph shows the total number of publications written about "Ligands" by people in this website by year, and whether "Ligands" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 6 | 6 |
| 1997 | 0 | 8 | 8 |
| 1998 | 1 | 6 | 7 |
| 1999 | 0 | 7 | 7 |
| 2000 | 0 | 9 | 9 |
| 2001 | 0 | 10 | 10 |
| 2002 | 0 | 15 | 15 |
| 2003 | 0 | 21 | 21 |
| 2004 | 0 | 14 | 14 |
| 2005 | 2 | 14 | 16 |
| 2006 | 1 | 13 | 14 |
| 2007 | 0 | 17 | 17 |
| 2008 | 0 | 12 | 12 |
| 2009 | 1 | 22 | 23 |
| 2010 | 1 | 9 | 10 |
| 2011 | 0 | 7 | 7 |
| 2012 | 2 | 19 | 21 |
| 2013 | 0 | 10 | 10 |
| 2014 | 0 | 13 | 13 |
| 2015 | 0 | 13 | 13 |
| 2016 | 0 | 14 | 14 |
| 2017 | 1 | 11 | 12 |
| 2018 | 0 | 15 | 15 |
| 2019 | 0 | 9 | 9 |
| 2020 | 1 | 19 | 20 |
| 2021 | 0 | 9 | 9 |
| 2022 | 0 | 19 | 19 |
| 2023 | 0 | 13 | 13 |
| 2024 | 0 | 7 | 7 |
| 2025 | 0 | 6 | 6 |
| 2026 | 0 | 6 | 6 |
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Below are the most recent publications written about "Ligands" by people in Profiles.
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The teneurin TEN-1 and its ligand LRON-11 support microbiota-induced neuroprotection and mechanosensory function in C. elegans. Curr Biol. 2026 Oct 05; 36(19):5068-5078.e6.
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Docking-score landscapes shape active-learning performance across Vina, Glide, and SILCS. J Comput Aided Mol Des. 2026 Sep 11; 40(1).
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Ligand-tuned extracellular domain dynamics are correlated with signaling states in an adhesion GPCR. Sci Adv. 2026 Aug 14; 12(33):eaea8715.
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Structural basis for domain coupling in heteromeric glycine receptors revealed by an atypical allosteric agonist. Sci Adv. 2026 Feb 13; 12(7):eaeb2036.
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Adhesion G protein-coupled receptors. Pharmacol Rev. 2026 May; 78(3):100116.
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The Role of Architectural Forces in Ion Selectivity. Adv Exp Med Biol. 2026; 1497:3-18.
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A dendritic guidance receptor functions in both ligand dependent and independent modes. PLoS Genet. 2025 Dec; 21(12):e1011942.
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Functional Relevance of CASP16 Nucleic Acid Predictions as Evaluated by Structure Providers. Proteins. 2026 Jan; 94(1):51-78.
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Mechanistic studies of small molecule ligands selective to RNA single G bulges. Nucleic Acids Res. 2025 Jun 20; 53(12).
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Telomerase reverse transcriptase degradation via a rationally designed covalent proteolysis targeting chimera. Bioorg Med Chem Lett. 2025 Sep 01; 125-126:130286.