"Protein Conformation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The characteristic 3-dimensional shape of a protein, including the secondary, supersecondary (motifs), tertiary (domains) and quaternary structure of the peptide chain. PROTEIN STRUCTURE, QUATERNARY describes the conformation assumed by multimeric proteins (aggregates of more than one polypeptide chain).
| Descriptor ID |
D011487
|
| MeSH Number(s) |
G02.111.570.820.709
|
| Concept/Terms |
Protein Conformation- Protein Conformation
- Conformation, Protein
- Conformations, Protein
- Protein Conformations
|
Below are MeSH descriptors whose meaning is more general than "Protein Conformation".
Below are MeSH descriptors whose meaning is more specific than "Protein Conformation".
This graph shows the total number of publications written about "Protein Conformation" by people in this website by year, and whether "Protein Conformation" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 20 | 21 |
| 1995 | 1 | 10 | 11 |
| 1996 | 5 | 13 | 18 |
| 1997 | 5 | 8 | 13 |
| 1998 | 4 | 16 | 20 |
| 1999 | 1 | 18 | 19 |
| 2000 | 0 | 16 | 16 |
| 2001 | 0 | 15 | 15 |
| 2002 | 3 | 22 | 25 |
| 2003 | 1 | 27 | 28 |
| 2004 | 3 | 30 | 33 |
| 2005 | 2 | 29 | 31 |
| 2006 | 0 | 31 | 31 |
| 2007 | 5 | 24 | 29 |
| 2008 | 2 | 24 | 26 |
| 2009 | 3 | 25 | 28 |
| 2010 | 4 | 22 | 26 |
| 2011 | 3 | 18 | 21 |
| 2012 | 2 | 24 | 26 |
| 2013 | 5 | 14 | 19 |
| 2014 | 4 | 17 | 21 |
| 2015 | 2 | 22 | 24 |
| 2016 | 1 | 30 | 31 |
| 2017 | 1 | 15 | 16 |
| 2018 | 3 | 30 | 33 |
| 2019 | 4 | 13 | 17 |
| 2020 | 0 | 14 | 14 |
| 2021 | 2 | 17 | 19 |
| 2022 | 1 | 5 | 6 |
| 2023 | 0 | 1 | 1 |
| 2024 | 0 | 5 | 5 |
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Below are the most recent publications written about "Protein Conformation" by people in Profiles.
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A Method for Treating Significant Conformational Changes in Alchemical Free Energy Simulations of Protein-Ligand Binding. J Chem Theory Comput. 2024 Oct 08; 20(19):8609-8623.
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Serial X-ray liquidography: multi-dimensional assay framework for exploring biomolecular structural dynamics with microgram quantities. Nat Commun. 2024 Jul 26; 15(1):6287.
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Structural analysis of the dynamic ribosome-translocon complex. Elife. 2024 Jun 18; 13.
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Functional protein dynamics in a crystal. Nat Commun. 2024 Apr 15; 15(1):3244.
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Engineered antigen-binding fragments for enhanced crystallization of antibody:antigen complexes. Protein Sci. 2024 Jan; 33(1):e4824.
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Conformation-specific Synthetic Antibodies Discriminate Multiple Functional States of the Ion Channel CorA. J Mol Biol. 2023 09 01; 435(17):168192.
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Architecture of the cytoplasmic face of the nuclear pore. Science. 2022 06 10; 376(6598):eabm9129.
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Structural basis for the mechanisms of human presequence protease conformational switch and substrate recognition. Nat Commun. 2022 04 05; 13(1):1833.
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Challenges and Advantages of Accounting for Backbone Flexibility in Prediction of Protein-Protein Complexes. J Chem Theory Comput. 2022 Mar 08; 18(3):2016-2032.
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Intrinsically Disordered Proteins: Critical Components of the Wetware. Chem Rev. 2022 03 23; 122(6):6614-6633.