"Phentolamine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A nonselective alpha-adrenergic antagonist. It is used in the treatment of hypertension and hypertensive emergencies, pheochromocytoma, vasospasm of RAYNAUD DISEASE and frostbite, clonidine withdrawal syndrome, impotence, and peripheral vascular disease.
Descriptor ID |
D010646
|
MeSH Number(s) |
D03.383.129.308.754
|
Concept/Terms |
Phentolamine Mesylate- Phentolamine Mesylate
- Mesylate, Phentolamine
- Phentolamine Methanesulfonate
- Methanesulfonate, Phentolamine
- Phentolamine Mesilate
- Mesilate, Phentolamine
|
Below are MeSH descriptors whose meaning is more general than "Phentolamine".
Below are MeSH descriptors whose meaning is more specific than "Phentolamine".
This graph shows the total number of publications written about "Phentolamine" by people in this website by year, and whether "Phentolamine" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1995 | 1 | 0 | 1 |
1997 | 0 | 1 | 1 |
2001 | 0 | 1 | 1 |
2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Phentolamine" by people in Profiles.
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Why drugs fail in clinical trials in pulmonary arterial hypertension, and strategies to succeed in the future. Pharmacol Ther. 2016 08; 164:195-203.
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Activation of extracellular signal-regulated kinases, NF-kappa B, and cyclic adenosine 5'-monophosphate response element-binding protein in lung neutrophils occurs by differing mechanisms after hemorrhage or endotoxemia. J Immunol. 2001 Jan 01; 166(1):522-30.
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Hemorrhage increases cytokine expression in lung mononuclear cells in mice: involvement of catecholamines in nuclear factor-kappaB regulation and cytokine expression. J Clin Invest. 1997 Apr 01; 99(7):1516-24.
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Papaverine-phentolamine and prostaglandin E1 versus papaverine-phentolamine alone for intracorporeal injection therapy: a clinical double-blind study. J Urol. 1995 Sep; 154(3):1017-9.
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Chart for preparation of dilutions of alpha-adrenergic agonists for intracavernous use in treatment of priapism. J Urol. 1995 Apr; 153(4):1182-3.
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Hemodynamic changes associated with obstructive sleep apnea followed by arousal in a porcine model. J Appl Physiol (1985). 1993 Oct; 75(4):1439-43.
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Objective double-blind evaluation of erectile function with intracorporeal papaverine in combination with phentolamine and/or prostaglandin E1. J Urol. 1992 Oct; 148(4):1181-3.
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Antinociception induced by electrical stimulation of spinally projecting noradrenergic neurons in the A7 catecholamine cell group of the rat. Pain. 1992 Mar; 48(3):449-461.
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Nocturnal penile tumescence predicting response to intracorporeal pharmacological erection testing. J Urol. 1988 Sep; 140(3):518-22.
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Autonomic response characteristics of porcine airway smooth muscle in vivo. J Appl Physiol (1985). 1985 Apr; 58(4):1176-88.