 Polyglutamic Acid
"Polyglutamic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A peptide that is a homopolymer of glutamic acid.
| Descriptor ID |
D011099
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| MeSH Number(s) |
D12.125.067.750.400.700 D12.125.119.450.400.700 D12.644.748
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Polyglutamic Acid".
Below are MeSH descriptors whose meaning is more specific than "Polyglutamic Acid".
This graph shows the total number of publications written about "Polyglutamic Acid" by people in this website by year, and whether "Polyglutamic Acid" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1980 | 1 | 0 | 1 | | 1981 | 1 | 0 | 1 | | 1982 | 2 | 0 | 2 | | 1983 | 1 | 0 | 1 | | 1985 | 1 | 0 | 1 | | 1996 | 1 | 0 | 1 | | 2000 | 1 | 0 | 1 | | 2008 | 0 | 1 | 1 | | 2010 | 1 | 0 | 1 | | 2012 | 1 | 0 | 1 | | 2015 | 0 | 1 | 1 | | 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Polyglutamic Acid" by people in Profiles.
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Rimmerman D, Leshchev D, Hsu DJ, Hong J, Abraham B, Henning R, Kosheleva I, Chen LX. Revealing Fast Structural Dynamics in pH-Responsive Peptides with Time-Resolved X-ray Scattering. J Phys Chem B. 2019 03 07; 123(9):2016-2021.
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Oh SY, Richter SG, Missiakas DM, Schneewind O. Glutamate Racemase Mutants of Bacillus anthracis. J Bacteriol. 2015 Jun; 197(11):1854-61.
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Lollo G, Rivera-Rodriguez GR, Bejaud J, Montier T, Passirani C, Benoit JP, García-Fuentes M, Alonso MJ, Torres D. Polyglutamic acid-PEG nanocapsules as long circulating carriers for the delivery of docetaxel. Eur J Pharm Biopharm. 2014 May; 87(1):47-54.
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Garufi G, Wang YT, Oh SY, Maier H, Missiakas DM, Schneewind O. Sortase-conjugation generates a capsule vaccine that protects guinea pigs against Bacillus anthracis. Vaccine. 2012 May 14; 30(23):3435-44.
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Kashiwaya K, Nakagawa H, Hosokawa M, Mochizuki Y, Ueda K, Piao L, Chung S, Hamamoto R, Eguchi H, Ohigashi H, Ishikawa O, Janke C, Shinomura Y, Nakamura Y. Involvement of the tubulin tyrosine ligase-like family member 4 polyglutamylase in PELP1 polyglutamylation and chromatin remodeling in pancreatic cancer cells. Cancer Res. 2010 May 15; 70(10):4024-33.
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Richter S, Anderson VJ, Garufi G, Lu L, Budzik JM, Joachimiak A, He C, Schneewind O, Missiakas D. Capsule anchoring in Bacillus anthracis occurs by a transpeptidation reaction that is inhibited by capsidin. Mol Microbiol. 2009 Jan; 71(2):404-20.
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Wesson JA, Worcester EM, Kleinman JG. Role of anionic proteins in kidney stone formation: interaction between model anionic polypeptides and calcium oxalate crystals. J Urol. 2000 Apr; 163(4):1343-8.
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Schilsky RL. Methotrexate: an effective agent for treating cancer and building careers. The polyglutamate era. Stem Cells. 1996 Jan; 14(1):29-32.
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Schilsky RL, Ordway FS. Insulin effects on methotrexate polyglutamate synthesis and enzyme binding in cultured human breast cancer cells. Cancer Chemother Pharmacol. 1985; 15(3):272-7.
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Schilsky RL, Jolivet J, Bailey BD, Chabner BA. Synthesis, binding and intracellular retention of methotrexate polyglutamates by cultured human breast cancer cells. Adv Exp Med Biol. 1983; 163:247-57.
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