"Disintegrins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of polypeptides purified from snake venoms, which contain the arginine-glycine-aspartic acid (RGD) sequence. The RGD tripeptide binds to integrin receptors and thus competitively inhibits normal integrin-ligand interactions. Disintegrins thus block adhesive functions and act as platelet aggregation inhibitors.
| Descriptor ID |
D019483
|
| MeSH Number(s) |
D12.644.138
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Disintegrins".
Below are MeSH descriptors whose meaning is more specific than "Disintegrins".
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Below are the most recent publications written about "Disintegrins" by people in Profiles.