Phosphoribosyl Pyrophosphate
"Phosphoribosyl Pyrophosphate" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The key substance in the biosynthesis of histidine, tryptophan, and purine and pyrimidine nucleotides.
| Descriptor ID |
D010754
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| MeSH Number(s) |
D09.894.643.650
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Phosphoribosyl Pyrophosphate".
Below are MeSH descriptors whose meaning is more specific than "Phosphoribosyl Pyrophosphate".
This graph shows the total number of publications written about "Phosphoribosyl Pyrophosphate" by people in this website by year, and whether "Phosphoribosyl Pyrophosphate" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 1 | 0 | 1 |
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Below are the most recent publications written about "Phosphoribosyl Pyrophosphate" by people in Profiles.
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Phosphoribosylpyrophosphate synthetase and the regulation of phosphoribosylpyrophosphate production in human cells. Prog Nucleic Acid Res Mol Biol. 2001; 69:115-48.
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PRPP and purine nucleotide metabolism in human lymphoblasts with both PRPP synthetase superactivity and HGPRT deficiency. Adv Exp Med Biol. 1989; 253B:13-20.
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Neurodevelopmental impairment and deranged PRPP and purine nucleotide synthesis in inherited superactivity of PRPP synthetase. Adv Exp Med Biol. 1989; 253A:15-22.
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Regulation of purine synthesis de novo in human fibroblasts by purine nucleotides and phosphoribosylpyrophosphate. J Biol Chem. 1987 Oct 25; 262(30):14531-7.
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Superactivity of human phosphoribosyl pyrophosphate synthetase due to altered regulation by nucleotide inhibitors and inorganic phosphate. Biochim Biophys Acta. 1986 Jun 19; 882(2):168-76.
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Selective expression of phosphoribosylpyrophosphate synthetase superactivity in human lymphoblast lines. J Clin Invest. 1985 Oct; 76(4):1657-64.
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The enzymatic synthesis of 5-amino-4-imidazolecarboxamide riboside triphosphate (ZTP). Science. 1984 Mar 16; 223(4641):1193-5.
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Mitogenic enhancement of purine base phosphoribosylation in Swiss mouse 3T3 cells. Am J Physiol. 1983 Mar; 244(3):C288-96.
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Gout with superactive phosphoribosylpyrophosphate synthetase due to increased enzyme catalytic rate. J Lab Clin Med. 1982 Apr; 99(4):495-511.
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Regulation of 5-phosphoribosyl-1-pyrophosphate synthesis in human fibroblasts by the concentration of inorganic phosphate. Biochim Biophys Acta. 1981 Nov 18; 678(1):58-64.