Ribose-Phosphate Pyrophosphokinase
"Ribose-Phosphate Pyrophosphokinase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the formation of phosphoribosyl pyrophosphate from ATP and ribose-5-phosphate. EC 2.7.6.1.
| Descriptor ID |
D012268
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| MeSH Number(s) |
D08.811.913.696.175.650
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| Concept/Terms |
Ribose-Phosphate Pyrophosphokinase- Ribose-Phosphate Pyrophosphokinase
- Pyrophosphokinase, Ribose-Phosphate
- Ribose Phosphate Pyrophosphokinase
- PRPP Synthetase
- Synthetase, PRPP
- PRibPP Synthetase
- Ribosephosphate Pyrophosphokinase
- Pyrophosphokinase, Ribosephosphate
- 5-Phospho-alpha-D-Ribose 1-Diphosphate Synthetase
- 1-Diphosphate Synthetase, 5-Phospho-alpha-D-Ribose
- 5 Phospho alpha D Ribose 1 Diphosphate Synthetase
- Synthetase, 5-Phospho-alpha-D-Ribose 1-Diphosphate
- Phosphoribosyl Pyrophosphate Synthetase
- Pyrophosphate Synthetase, Phosphoribosyl
- Synthetase, Phosphoribosyl Pyrophosphate
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Below are MeSH descriptors whose meaning is more general than "Ribose-Phosphate Pyrophosphokinase".
Below are MeSH descriptors whose meaning is more specific than "Ribose-Phosphate Pyrophosphokinase".
This graph shows the total number of publications written about "Ribose-Phosphate Pyrophosphokinase" by people in this website by year, and whether "Ribose-Phosphate Pyrophosphokinase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 2 | 0 | 2 |
| 1996 | 2 | 0 | 2 |
| 1998 | 1 | 0 | 1 |
| 1999 | 1 | 0 | 1 |
| 2000 | 1 | 0 | 1 |
| 2001 | 1 | 0 | 1 |
| 2003 | 1 | 0 | 1 |
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Below are the most recent publications written about "Ribose-Phosphate Pyrophosphokinase" by people in Profiles.
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Phosphoribosylpyrophosphate synthetase overactivity as a cause of uric acid overproduction in a young woman. Arthritis Rheum. 2003 Jul; 48(7):2036-41.
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Phosphoribosylpyrophosphate synthetase and the regulation of phosphoribosylpyrophosphate production in human cells. Prog Nucleic Acid Res Mol Biol. 2001; 69:115-48.
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Cell type-specific differential expression of human PRPP synthetase (PRPS) genes. Adv Exp Med Biol. 2000; 486:5-10.
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Accelerated transcription of PRPS1 in X-linked overactivity of normal human phosphoribosylpyrophosphate synthetase. J Biol Chem. 1999 Mar 12; 274(11):7482-8.
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Regulation of human PRS isoform expression. Adv Exp Med Biol. 1998; 431:215-20.
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Overexpression of the normal phosphoribosylpyrophosphate synthetase 1 isoform underlies catalytic superactivity of human phosphoribosylpyrophosphate synthetase. J Biol Chem. 1996 Aug 16; 271(33):19894-9.
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Determination of phosphoribosylpyrophosphate synthetase activity in human cells by a non-isotopic, one step method. Clin Chim Acta. 1996 Feb 09; 245(1):105-12.
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The genetic and functional basis of purine nucleotide feedback-resistant phosphoribosylpyrophosphate synthetase superactivity. J Clin Invest. 1995 Nov; 96(5):2133-41.
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Inhibition of human 5-phosphoribosyl-1-pyrophosphate synthetase by 4-amino-8-(beta-D-ribofuranosylamino)-pyrimido[5,4-d]pyrimidine-5'- monophosphate: evidence for interaction at the ADP allosteric site. Mol Pharmacol. 1995 Apr; 47(4):810-5.
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A simplified method for the determination of phosphoribosylpyrophosphate synthetase activity in hemolysates. Clin Chim Acta. 1994 Jan 14; 224(1):55-63.