 Prealbumin
"Prealbumin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A tetrameric protein, molecular weight between 50,000 and 70,000, consisting of 4 equal chains, and migrating on electrophoresis in 3 fractions more mobile than serum albumin. Its concentration ranges from 7 to 33 per cent in the serum, but levels decrease in liver disease.
| Descriptor ID |
D011228
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| MeSH Number(s) |
D12.776.034.841.450 D12.776.124.727.450
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Prealbumin".
Below are MeSH descriptors whose meaning is more specific than "Prealbumin".
This graph shows the total number of publications written about "Prealbumin" by people in this website by year, and whether "Prealbumin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1984 | 0 | 1 | 1 | | 1986 | 1 | 0 | 1 | | 1989 | 1 | 0 | 1 | | 1996 | 1 | 0 | 1 | | 2002 | 1 | 0 | 1 | | 2007 | 1 | 0 | 1 | | 2008 | 0 | 1 | 1 | | 2012 | 1 | 0 | 1 | | 2014 | 0 | 1 | 1 |
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Below are the most recent publications written about "Prealbumin" by people in Profiles.
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Thenappan T, Fedson S, Rich J, Murks C, Husain A, Pogoriler J, Anderson AS. Isolated heart transplantation for familial transthyretin (TTR) V122I cardiac amyloidosis. Amyloid. 2014 Jun; 21(2):120-3.
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Monk JA, Sims NA, Dziegielewska KM, Weiss RE, Ramsay RG, Richardson SJ. Delayed development of specific thyroid hormone-regulated events in transthyretin null mice. Am J Physiol Endocrinol Metab. 2013 Jan 01; 304(1):E23-31.
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Noborn F, O'Callaghan P, Hermansson E, Zhang X, Ancsin JB, Damas AM, Dacklin I, Presto J, Johansson J, Saraiva MJ, Lundgren E, Kisilevsky R, Westermark P, Li JP. Heparan sulfate/heparin promotes transthyretin fibrillization through selective binding to a basic motif in the protein. Proc Natl Acad Sci U S A. 2011 Apr 05; 108(14):5584-9.
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Wan DC, Kwan MD, Gupta DM, Wang Z, Slater BJ, Panetta NJ, Morrell NT, Longaker MT. Global age-dependent differences in gene expression in response to calvarial injury. J Craniofac Surg. 2008 Sep; 19(5):1292-301.
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Choi SH, Leight SN, Lee VM, Li T, Wong PC, Johnson JA, Saraiva MJ, Sisodia SS. Accelerated Abeta deposition in APPswe/PS1deltaE9 mice with hemizygous deletions of TTR (transthyretin). J Neurosci. 2007 Jun 27; 27(26):7006-10.
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Prendergast BJ, Mosinger B, Kolattukudy PE, Nelson RJ. Hypothalamic gene expression in reproductively photoresponsive and photorefractory Siberian hamsters. Proc Natl Acad Sci U S A. 2002 Dec 10; 99(25):16291-6.
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Refetoff S, Marinov VS, Tunca H, Byrne MM, Sunthornthepvarakul T, Weiss RE. A new family with hyperthyroxinemia caused by transthyretin Val109 misdiagnosed as thyrotoxicosis and resistance to thyroid hormone--a clinical research center study. J Clin Endocrinol Metab. 1996 Sep; 81(9):3335-40.
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Rhodes CJ, Brennan SO, Hutton JC. Proalbumin to albumin conversion by a proinsulin processing endopeptidase of insulin secretory granules. J Biol Chem. 1989 Aug 25; 264(24):14240-5.
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Refetoff S, Dwulet FE, Benson MD. Reduced affinity for thyroxine in two of three structural thyroxine-binding prealbumin variants associated with familial amyloidotic polyneuropathy. J Clin Endocrinol Metab. 1986 Dec; 63(6):1432-7.
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Pearl GS, Check IJ, Hunter RL. Agarose electrophoresis and immunonephelometric quantitation of cerebrospinal fluid immunoglobulins: criteria for application in the diagnosis of neurologic disease. Am J Clin Pathol. 1984 May; 81(5):575-80.
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