 Quinacrine
"Quinacrine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.
| Descriptor ID |
D011796
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| MeSH Number(s) |
D03.494.046.250.760
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Quinacrine".
Below are MeSH descriptors whose meaning is more specific than "Quinacrine".
This graph shows the total number of publications written about "Quinacrine" by people in this website by year, and whether "Quinacrine" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1984 | 0 | 1 | 1 | | 1989 | 1 | 0 | 1 | | 1993 | 0 | 1 | 1 | | 1996 | 0 | 1 | 1 | | 2002 | 0 | 1 | 1 | | 2003 | 0 | 1 | 1 |
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Below are the most recent publications written about "Quinacrine" by people in Profiles.
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Wallin C, Abbas AK, Tranberg M, Weber SG, Wigström H, Sandberg M. Searching for mechanisms of N-methyl-D-aspartate-induced glutathione efflux in organotypic hippocampal cultures. Neurochem Res. 2003 Feb; 28(2):281-91.
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Di A, Krupa B, Bindokas VP, Chen Y, Brown ME, Palfrey HC, Naren AP, Kirk KL, Nelson DJ. Quantal release of free radicals during exocytosis of phagosomes. Nat Cell Biol. 2002 Apr; 4(4):279-85.
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Caggiano AO, Breder CD, Kraig RP. Long-term elevation of cyclooxygenase-2, but not lipoxygenase, in regions synaptically distant from spreading depression. J Comp Neurol. 1996 Dec 16; 376(3):447-62.
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Becker BN, Cheng HF, Burns KD, Harris RC. Polarized rabbit type 1 angiotensin II receptors manifest differential rates of endocytosis and recycling. Am J Physiol. 1995 Oct; 269(4 Pt 1):C1048-56.
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White SR, Strek ME, Kulp GV, Spaethe SM, Burch RA, Neeley SP, Leff AR. Regulation of human eosinophil degranulation and activation by endogenous phospholipase A2. J Clin Invest. 1993 May; 91(5):2118-25.
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Favus MJ, Tembe V, Tanklefsky MD, Ambrosic KA, Nellans HN. Effects of quinacrine on calcium active transport by rat intestinal epithelium. Am J Physiol. 1989 Nov; 257(5 Pt 1):G818-22.
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Vicentini LM, Miller RJ, Villereal ML. Evidence for a role of phospholipase activity in the serum stimulation of Na+ influx in human fibroblasts. J Biol Chem. 1984 Jun 10; 259(11):6912-9.
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Golomb HM, Vardiman JW, Rowley JD, Testa JR, Mintz U. Correlation of clinical findings with quinacrine-banded chromosomes in 90 adults with acute nonlymphocytic leukemia: an eight-year study (1970-1977). N Engl J Med. 1978 Sep 21; 299(12):613-9.
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Sellyei M, Vass L, Krausz T. Non-random appearance of Y-chromatin-like fluorescence in the nuclei of thyroid and brain and its chromosomal background. Humangenetik. 1975; 27(4):339-42.
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Golomb HM, Bahr GF. Correlation of the fluorescent banding pattern and ultrastructure of a human chromosome. Exp Cell Res. 1974 Mar 15; 84(1):121-6.
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