"S-Adenosylmethionine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Physiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all living organisms. It possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. (From Merck, 11th ed)
| Descriptor ID |
D012436
|
| MeSH Number(s) |
D02.886.030.676.180 D03.633.100.759.590.138.264 D12.125.166.676.180 D13.570.583.138.264 D13.570.800.096.264
|
| Concept/Terms |
S-Adenosylmethionine- S-Adenosylmethionine
- S Adenosylmethionine
- SAM-e
- AdoMet
- S-Adenosyl-L-Methionine
- S Adenosyl L Methionine
- Ademetionine
|
Below are MeSH descriptors whose meaning is more general than "S-Adenosylmethionine".
Below are MeSH descriptors whose meaning is more specific than "S-Adenosylmethionine".
This graph shows the total number of publications written about "S-Adenosylmethionine" by people in this website by year, and whether "S-Adenosylmethionine" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 2 | 2 |
| 2010 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 1 | 1 | 2 |
| 2018 | 3 | 0 | 3 |
| 2019 | 1 | 3 | 4 |
| 2020 | 1 | 0 | 1 |
| 2021 | 0 | 2 | 2 |
| 2022 | 1 | 0 | 1 |
| 2023 | 0 | 2 | 2 |
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Below are the most recent publications written about "S-Adenosylmethionine" by people in Profiles.
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Discovery of a Druggable, Cryptic Pocket in SARS-CoV-2 nsp16 Using Allosteric Inhibitors. ACS Infect Dis. 2023 10 13; 9(10):1918-1931.
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Lack of Association of C677T Methylenetetrahydrofolate Reductase Polymorphism with Breast Cancer Risk in Mali. Genet Res (Camb). 2023; 2023:4683831.
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mTORC1-independent translation control in mammalian cells by methionine adenosyltransferase 2A and S-adenosylmethionine. J Biol Chem. 2022 07; 298(7):102084.
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Dph3 Enables Aerobic Diphthamide Biosynthesis by Donating One Iron Atom to Transform a [3Fe-4S] to a [4Fe-4S] Cluster in Dph1-Dph2. J Am Chem Soc. 2021 06 30; 143(25):9314-9319.
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2'-O methylation of RNA cap in SARS-CoV-2 captured by serial crystallography. Proc Natl Acad Sci U S A. 2021 05 25; 118(21).
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Methyl-Metabolite Depletion Elicits Adaptive Responses to Support Heterochromatin Stability and Epigenetic Persistence. Mol Cell. 2020 04 16; 78(2):210-223.e8.
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Transsulfuration Activity Can Support Cell Growth upon Extracellular Cysteine Limitation. Cell Metab. 2019 11 05; 30(5):865-876.e5.
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The asymmetric function of Dph1-Dph2 heterodimer in diphthamide biosynthesis. J Biol Inorg Chem. 2019 09; 24(6):777-782.
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Proteomics reveals NNMT as a master metabolic regulator of cancer-associated fibroblasts. Nature. 2019 05; 569(7758):723-728.
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Altered Methionine Metabolism in Cancer Cells. Methods Mol Biol. 2019; 1866:13-26.