 Receptors, Adrenergic, alpha
"Receptors, Adrenergic, alpha" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
One of the two major pharmacological subdivisions of adrenergic receptors that were originally defined by the relative potencies of various adrenergic compounds. The alpha receptors were initially described as excitatory receptors that post-junctionally stimulate SMOOTH MUSCLE contraction. However, further analysis has revealed a more complex picture involving several alpha receptor subtypes and their involvement in feedback regulation.
| Descriptor ID |
D011942
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| MeSH Number(s) |
D12.776.543.750.070.300.300.300 D12.776.543.750.100.150.300.300 D12.776.543.750.720.300.300.300.300
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| Concept/Terms |
Receptors, Adrenergic, alpha- Receptors, Adrenergic, alpha
- Receptors, alpha-Adrenergic
- Receptors, alpha Adrenergic
- Receptor, Adrenergic, alpha
- Adrenergic alpha-Receptors
- Adrenergic alpha Receptors
- alpha-Receptors, Adrenergic
- alpha-Adrenergic Receptors
- alpha Adrenergic Receptors
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Adrenergic, alpha".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Biogenic Amine [D12.776.543.750.070]
- Receptors, Catecholamine [D12.776.543.750.070.300]
- Receptors, Adrenergic [D12.776.543.750.070.300.300]
- Receptors, Adrenergic, alpha [D12.776.543.750.070.300.300.300]
- Receptors, G-Protein-Coupled [D12.776.543.750.100]
- Receptors, Catecholamine [D12.776.543.750.100.150]
- Receptors, Adrenergic [D12.776.543.750.100.150.300]
- Receptors, Adrenergic, alpha [D12.776.543.750.100.150.300.300]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Biogenic Amine [D12.776.543.750.720.300]
- Receptors, Catecholamine [D12.776.543.750.720.300.300]
- Receptors, Adrenergic [D12.776.543.750.720.300.300.300]
- Receptors, Adrenergic, alpha [D12.776.543.750.720.300.300.300.300]
Below are MeSH descriptors whose meaning is more specific than "Receptors, Adrenergic, alpha".
This graph shows the total number of publications written about "Receptors, Adrenergic, alpha" by people in this website by year, and whether "Receptors, Adrenergic, alpha" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1981 | 2 | 0 | 2 | | 1982 | 1 | 1 | 2 | | 1983 | 1 | 0 | 1 | | 1985 | 1 | 0 | 1 | | 1986 | 1 | 0 | 1 | | 1987 | 2 | 0 | 2 | | 1988 | 1 | 0 | 1 | | 1989 | 0 | 1 | 1 | | 1991 | 2 | 0 | 2 | | 1992 | 1 | 0 | 1 | | 1998 | 1 | 0 | 1 | | 1999 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Receptors, Adrenergic, alpha" by people in Profiles.
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Chen EP, Akhter SA, Bittner HB, Koch WJ, Davis RD, Van Trigt P. Molecular and functional mechanisms of right ventricular adaptation in chronic pulmonary hypertension. Ann Thorac Surg. 1999 Apr; 67(4):1053-8.
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Akhter SA, Luttrell LM, Rockman HA, Iaccarino G, Lefkowitz RJ, Koch WJ. Targeting the receptor-Gq interface to inhibit in vivo pressure overload myocardial hypertrophy. Science. 1998 Apr 24; 280(5363):574-7.
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Maginniss LA, Connolly H, Samsel RW, Schumacker PT. Adrenergic vasoconstriction augments tissue O2 extraction during reductions in O2 delivery. J Appl Physiol (1985). 1994 Apr; 76(4):1454-61.
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Liao JK, Homcy CJ. Specific receptor-guanine nucleotide binding protein interaction mediates the release of endothelium-derived relaxing factor. Circ Res. 1992 May; 70(5):1018-26.
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Kou YR, Ernsberger P, Cragg PA, Cherniack NS, Prabhakar NR. Role of alpha 2-adrenergic receptors in the carotid body response to isocapnic hypoxia. Respir Physiol. 1991 Mar; 83(3):353-64.
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Hsieh WT, Barrick JL, Hoehe MR, Gershon ES. A notI RFLP in the human alpha 2-C4 adrenergic receptor locus (ADRA2RL2) detected by PFGE. Nucleic Acids Res. 1991 Jan 11; 19(1):198.
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Conway S, Richardson L, Speciale S, Moherek R, Mauceri H, Krulich L. Interaction between norepinephrine and serotonin in the neuroendocrine control of growth hormone release in the rat. Endocrinology. 1990 Feb; 126(2):1022-30.
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Baroody F, Proud D, Kagey-Sobotka A, Freidhoff L, Norman PS, Lichtenstein LM, Naclerio RM. The effects of H1 antihistamines on the early allergic response. Ann Allergy. 1989 Dec; 63(6 Pt 2):551-5.
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Kroeger EA, Bergen JM, Mitchell RW. Effect of active sensitization on canine airway smooth muscle responsiveness to adrenergic and cholinergic mechanisms in vitro. Prog Clin Biol Res. 1988; 263:219-30.
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Mastrianni JA, Ingenito AJ. On the relationship between clonidine hypotension and brain beta-endorphin in the spontaneously hypertensive rat: studies with alpha adrenergic and opiate blockers. J Pharmacol Exp Ther. 1987 Jul; 242(1):378-87.
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