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Shahab Akhter

TitleASSOCIATE PROFESSOR
InstitutionUniversity of Chicago
DepartmentSurgery
AddressChicago IL 60637
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    Collapse Research 
    Collapse research activities and funding
    R01HL107949     (AKHTER, SHAHAB A)Jun 1, 2011 - Jun 30, 2016
    NIH
    Inhibition of GRK2 to Prevent Ventricular Remodeling and Heart Failure After CABG
    Role: Principal Investigator
    K08HL081472     (AKHTER, SHAHAB A)Sep 29, 2005 - Jul 31, 2010
    NIH
    Myocardial Regulation of betaARK1 by Protein Kinase C
    Role: Principal Investigator
    F32HL009436     (AKHTER, SHAHAB A)Oct 7, 1996
    NIH
    GG MEDIATED PATHWAYS AND VENTRICULAR HYPE
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Fu Y, Oh S, Quinn S, Bethea JP, Mendes OJ, Kindell L, Irish W, Akhter SA, Peine BS. Impact of timing of urgent coronary artery bypass grafting following coronary angiography on acute kidney injury. J Thorac Cardiovasc Surg. 2024 Aug; 168(2):533-542. PMID: 37356474.
      Citations:    Fields:    Translation:Humans
    2. Rogers AL, Akhter SA. Platelet Function Testing-Based Timing of Urgent Coronary Artery Bypass Grafting After Treatment With P2Y12 Inhibitors. Ann Thorac Surg. 2023 05; 115(5):1331-1332. PMID: 36115388.
      Citations:    Fields:    Translation:Humans
    3. Berdaweel IA, Hart AA, Jatis AJ, Karlan N, Akhter SA, Gaine ME, Smith RM, Anderson EJ. A Genotype-Phenotype Analysis of Glutathione Peroxidase 4 in Human Atrial Myocardium and Its Association with Postoperative Atrial Fibrillation. Antioxidants (Basel). 2022 Apr 06; 11(4). PMID: 35453406; PMCID: PMC9026099.
      Citations: 1     
    4. Degner BC, Akhter SA, Allman RD, Rogers AL, Popowicz P, Fang X, Bell RA, Bates MJ. Response to Letter to the Editor-Analysis of racial disparities in acute type A aortic dissection repair at a rural tertiary academic medical center. J Card Surg. 2022 01; 37(1):263-264. PMID: 34643291.
      Citations:    Fields:    Translation:Humans
    5. Allman RD, Rogers AL, Popowicz P, Fang X, Bell RA, Bates MJ, Akhter SA, Degner BC. Analysis of racial disparities in acute type A aortic dissection repair at a rural tertiary academic medical center. J Card Surg. 2021 Nov; 36(11):4238-4242. PMID: 34499373.
      Citations:    Fields:    Translation:Humans
    6. Rogers AL, Allman RD, Fang X, Kindell LC, Nifong LW, Degner BC, Akhter SA. Thromboelastography-Platelet Mapping Allows Safe and Earlier Urgent Coronary Artery Bypass Grafting. Ann Thorac Surg. 2022 04; 113(4):1119-1125. PMID: 34437860.
      Citations: 2     Fields:    Translation:HumansCells
    7. Nelson MM, Efird JT, Kew KA, Katunga LA, Monroe TB, Doorn JA, Beatty CN, Shi Q, Akhter SA, Alwair H, Robidoux J, Anderson EJ. Enhanced Catecholamine Flux and Impaired Carbonyl Metabolism Disrupt Cardiac Mitochondrial Oxidative Phosphorylation in Diabetes Patients. Antioxid Redox Signal. 2021 08 01; 35(4):235-251. PMID: 33066717; PMCID: PMC8262387.
      Citations: 9     Fields:    Translation:HumansCells
    8. Dali DC, Jhamb S, Powell CS, Akhter SA. Combined surgical treatment of symptomatic carotid, coronary and mesenteric occlusive disease. J Surg Case Rep. 2020 Feb; 2020(2):rjz392. PMID: 32064075; PMCID: PMC7015075.
      Citations: 1     
    9. Sengodan P, Kharazi A, Akhter SA, Nekkanti R. Rare Presentation of a Ruptured Sinus of Valsalva Aneurysm. CASE (Phila). 2020 Feb; 4(1):43-46. PMID: 32090190; PMCID: PMC7026451.
      Citations: 4     
    10. Philip JL, Xu X, Han M, Akhter SA, Razzaque MA. Regulation of cardiac fibroblast-mediated maladaptive ventricular remodeling by ß-arrestins. PLoS One. 2019; 14(7):e0219011. PMID: 31269046; PMCID: PMC6609028.
      Citations: 8     Fields:    Translation:AnimalsCells
    11. Razzaque MA, Xu X, Han M, Badami A, Akhter SA. Inhibition of Postinfarction Ventricular Remodeling by High Molecular Weight Polyethylene Glycol. J Surg Res. 2018 12; 232:171-178. PMID: 30463715.
      Citations: 2     Fields:    Translation:AnimalsCells
    12. Philip JL, Zens T, Lozonschi L, De Oliveira NC, Osaki S, Kohmoto T, Akhter SA, Tang PC. Outcomes of surgical aortic valve replacement for mixed aortic valve disease. J Thorac Dis. 2018 Jul; 10(7):4042-4051. PMID: 30174847; PMCID: PMC6106000.
      Citations: 4     
    13. Efird JT, Jindal C, Kiser AC, Akhter SA, Crane PB, Kypson AP, Sverdlov AL, Davies SW, Kindell LC, Anderson EJ. Increased risk of atrial fibrillation among patients undergoing coronary artery bypass graft surgery while receiving nitrates and antiplatelet agents. J Int Med Res. 2018 Aug; 46(8):3183-3194. PMID: 29808744; PMCID: PMC6134635.
      Citations: 1     Fields:    Translation:Humans
    14. Tang PC, DiMusto PD, De Oliveira NC, Rademacher BL, Philip JL, Akhter SA, Acher CW. Natural history of the proximal aorta in patients with descending thoracic aortic disease. J Vasc Surg. 2018 06; 67(6):1659-1663. PMID: 29276106; PMCID: PMC6942929.
      Citations:    Fields:    Translation:Humans
    15. Kohmoto T, Osaki S, Kaufman DB, Leverson G, DeOliveira N, Akhter SA, Ulschmid S, Lozonschi L, Lushaj EB. Cardiac Surgery Outcomes in Abdominal Solid Organ Transplant Recipients. Ann Thorac Surg. 2018 03; 105(3):757-762. PMID: 29174777.
      Citations: 3     Fields:    Translation:Humans
    16. Lozonschi L, Kohmoto T, Osaki S, De Oliveira NC, Dhingra R, Akhter SA, Tang PC. Coronary bypass in left ventricular dysfunction and differential cardiac recovery. Asian Cardiovasc Thorac Ann. 2017 Nov; 25(9):586-593. PMID: 29153000.
      Citations: 1     Fields:    Translation:Humans
    17. Philip JL, De Oliveira NC, Akhter SA, Rademacher BL, Goodavish CB, DiMusto PD, Tang PC. Cluster analysis of acute ascending aortic dissection provides novel insight into mechanisms of distal progression. J Thorac Dis. 2017 Sep; 9(9):2966-2973. PMID: 29221269; PMCID: PMC5708434.
      Citations: 2     
    18. Tang PC, Akhter SA, Osaki S, Lozonschi L, Kohmoto T, De Oliveira NC. Coronary Events in Patients Presenting for Repair of Acute Type A Aortic Dissection. Aorta (Stamford). 2017 Jun; 5(3):71-79. PMID: 29675439; PMCID: PMC5899605.
      Citations:    
    19. DiMusto PD, Rademacher BL, Philip JL, Akhter SA, Goodavish CB, De Oliveira NC, Tang PC. Acute retrograde type A aortic dissection: morphologic analysis and clinical implications. J Surg Res. 2017 06 01; 213:39-45. PMID: 28601330; PMCID: PMC6942928.
      Citations: 2     Fields:    Translation:Humans
    20. Lushaj EB, Dhingra R, Chindhy S, Akhter S, Kohmoto T, Ulschmid S, Osaki S, Badami A, Lozonschi L. To use or not to use? Amiodarone before heart transplantation. Surgery. 2017 05; 161(5):1273-1278. PMID: 27876282.
      Citations: 3     Fields:    Translation:Humans
    21. Tang PC, Badami A, Akhter SA, Osaki S, Lozonschi L, Kohmoto T, De Oliveira N. Efficacy of Aortic Valve Resuspension in Establishing Valve Competence in Acute Type A Dissections. Ann Thorac Surg. 2017 May; 103(5):1460-1466. PMID: 27863732.
      Citations: 4     Fields:    Translation:Humans
    22. Malhotra R, D'Souza KM, Staron ML, Birukov KG, Bodi I, Akhter SA. Gaq-mediated activation of GRK2 by mechanical stretch in cardiac myocytes. THE ROLE OF PROTEIN KINASE C. J Biol Chem. 2016 Jul 01; 291(27):14390. PMID: 27371566; PMCID: PMC4933195.
      Citations:    Fields:    
    23. Lushaj E, Julliard W, Akhter S, Leverson G, Maloney J, Cornwell RD, Meyer KC, DeOliveira N. Timing and Frequency of Unplanned Readmissions After Lung Transplantation Impact Long-Term Survival. Ann Thorac Surg. 2016 Aug; 102(2):378-84. PMID: 27154148.
      Citations: 4     Fields:    Translation:Humans
    24. Schmocker RK, Vanness DJ, Macke RA, Akhter SA, Maloney JD, Blasberg JD. Outpatient air leak management after lobectomy: a CMS cost analysis. J Surg Res. 2016 06 15; 203(2):390-7. PMID: 27363648; PMCID: PMC4926869.
      Citations: 7     Fields:    Translation:Humans
    25. Akhter SA. Continuous-flow left ventricular assist devices and bleeding events: Is there a biological role for decreasing pump speed? J Thorac Cardiovasc Surg. 2016 Jun; 151(6):1755-6. PMID: 26971386.
      Citations: 1     Fields:    Translation:Humans
    26. Afroz F, Rasool MT, Nasreen S, Lone MM, Wani ML, Akhter S, Zaffar S, Yousuf S, Akhter A. Cancer cervix: An uncommon malignancy in Kashmir, India. Indian J Cancer. 2016 Jan-Mar; 53(1):77-9. PMID: 27146748.
      Citations:    Fields:    Translation:Humans
    27. Theccanat T, Philip JL, Razzaque AM, Ludmer N, Li J, Xu X, Akhter SA. Regulation of cellular oxidative stress and apoptosis by G protein-coupled receptor kinase-2; The role of NADPH oxidase 4. Cell Signal. 2016 Mar; 28(3):190-203. PMID: 26631573; PMCID: PMC4837949.
      Citations: 25     Fields:    Translation:AnimalsCells
    28. Philip JL, Razzaque MA, Han M, Li J, Theccanat T, Xu X, Akhter SA. Regulation of mitochondrial oxidative stress by ß-arrestins in cultured human cardiac fibroblasts. Dis Model Mech. 2015 Dec; 8(12):1579-89. PMID: 26449263; PMCID: PMC4728312.
      Citations: 16     Fields:    Translation:HumansCells
    29. Akhter SA. Invited Commentary. Ann Thorac Surg. 2015 Oct; 100(4):1297. PMID: 26434431.
      Citations:    Fields:    Translation:Humans
    30. Badami A, Fehrenbach Prell EA, Murray MA, Johnson MR, Akhter SA, Lozonschi L, Osaki S, Lushaj E, Kohmoto T. A novel approach to prevent post-operative ileus after continuous-flow left ventricular assist device implantation: A retrospective cohort study. Int J Surg. 2015 Aug; 20:135-9. PMID: 26118604.
      Citations: 1     Fields:    Translation:Humans
    31. Akhter SA, Badami A, Murray M, Kohmoto T, Lozonschi L, Osaki S, Lushaj EB. Hospital Readmissions After Continuous-Flow Left Ventricular Assist Device Implantation: Incidence, Causes, and Cost Analysis. Ann Thorac Surg. 2015 Sep; 100(3):884-9. PMID: 26095106.
      Citations: 43     Fields:    Translation:Humans
    32. Lushaj EB, Badami A, Osaki S, Murray M, Leverson G, Lozonschi L, Akhter S, Kohmoto T. Impact of age on outcomes following continuous-flow left ventricular assist device implantation. Interact Cardiovasc Thorac Surg. 2015 Jun; 20(6):743-8. PMID: 25770085.
      Citations: 8     Fields:    Translation:Humans
    33. Dean D, Kallel F, Ewald GA, Tatooles A, Sheridan BC, Brewer RJ, Caldeira C, Farrar DJ, Akhter SA, SSI Registry Investigators. Reduction in driveline infection rates: Results from the HeartMate II Multicenter Driveline Silicone Skin Interface (SSI) Registry. J Heart Lung Transplant. 2015 Jun; 34(6):781-9. PMID: 25735901.
      Citations: 19     Fields:    Translation:Humans
    34. Russo MJ, Valeroso TB, Anderson AS, Rich JD, Jeevanandam V, Akhter SA, Singh A. Modified HeartMate II driveline externalization technique significantly decreases incidence of infection and improves long-term survival. ASAIO J. 2014 Nov-Dec; 60(6):613-6. PMID: 25072552.
      Citations: 10     Fields:    Translation:Humans
    35. Xu X, Philip JL, Razzaque MA, Lloyd JW, Muller CM, Akhter SA. High-molecular-weight polyethylene glycol inhibits myocardial ischemia-reperfusion injury in vivo. J Thorac Cardiovasc Surg. 2015 Feb; 149(2):588-93. PMID: 25455467; PMCID: PMC4459731.
      Citations: 10     Fields:    Translation:AnimalsCells
    36. Gemel J, Levy AE, Simon AR, Bennett KB, Ai X, Akhter S, Beyer EC. Connexin40 abnormalities and atrial fibrillation in the human heart. J Mol Cell Cardiol. 2014 Nov; 76:159-68. PMID: 25200600; PMCID: PMC4250516.
      Citations: 38     Fields:    Translation:HumansCells
    37. Li J, Philip JL, Xu X, Theccanat T, Abdur Razzaque M, Akhter SA. ß-Arrestins regulate human cardiac fibroblast transformation and collagen synthesis in adverse ventricular remodeling. J Mol Cell Cardiol. 2014 Nov; 76:73-83. PMID: 25134464; PMCID: PMC4250404.
      Citations: 24     Fields:    Translation:HumansCells
    38. Osaki S, Locher MR, Lushaj EB, Akhter SA, Kohmoto T. Functional evaluation of human donation after cardiac death donor hearts using a continuous isolated myocardial perfusion technique: Potential for expansion of the cardiac donor population. J Thorac Cardiovasc Surg. 2014 Sep; 148(3):1123-30; discussion 1130. PMID: 25129607.
      Citations: 6     Fields:    Translation:Humans
    39. Hoque MR, Chakraborty PK, Paul UK, Sarkar S, Akhter S, Shahidullah SM, Gautam B, Sultana S, Ferdous N, Samsunnahar M. Serum albumin and creatinine clearance rate among smear positive pulmonary tuberculosis patients in Bangladesh. Mymensingh Med J. 2014 Jul; 23(3):430-4. PMID: 25178592.
      Citations: 1     Fields:    Translation:Humans
    40. Akhter SA, Salabat MR, Philip JL, Valeroso TB, Russo MJ, Rich JD, Jeevanandam V. Durability of De Vega tricuspid valve annuloplasty for severe tricuspid regurgitation during left ventricular assist device implantation. Ann Thorac Surg. 2014 Jul; 98(1):81-3. PMID: 24820391.
      Citations: 4     Fields:    Translation:Humans
    41. Naik A, Akhter SA, Fedson S, Jeevanandam V, Rich JD, Koyner JL. Acute kidney injury and mortality following ventricular assist device implantation. Am J Nephrol. 2014; 39(3):195-203. PMID: 24556808; PMCID: PMC4000722.
      Citations: 5     Fields:    Translation:Humans
    42. Russo MJ, Merlo A, Johnson EM, Akhter S, McCarney S, Steiman J, Anderson A, Jeevanandam V. Transapical approach for mitral valve repair during insertion of a left ventricular assist device. ScientificWorldJournal. 2013; 2013:925310. PMID: 23878531; PMCID: PMC3710651.
      Citations: 3     Fields:    Translation:Humans
    43. Akhter SA. Invited commentary. Ann Thorac Surg. 2013 Apr; 95(4):1281. PMID: 23522195.
      Citations:    Fields:    Translation:Humans
    44. Akhter S, Abeyratne UR, Swarnkar V. Variations of snoring properties with macro sleep stages in a population of Obstructive Sleep Apnea patients. Annu Int Conf IEEE Eng Med Biol Soc. 2013; 2013:1318-21. PMID: 24109938.
      Citations: 1     Fields:    Translation:Humans
    45. Akhter SA. Invited commentary. Ann Thorac Surg. 2013 Jan; 95(1):61-2. PMID: 23272829.
      Citations:    Fields:    Translation:Humans
    46. Piao L, Fang YH, Parikh KS, Ryan JJ, D'Souza KM, Theccanat T, Toth PT, Pogoriler J, Paul J, Blaxall BC, Akhter SA, Archer SL. GRK2-mediated inhibition of adrenergic and dopaminergic signaling in right ventricular hypertrophy: therapeutic implications in pulmonary hypertension. Circulation. 2012 Dec 11; 126(24):2859-69. PMID: 23124027; PMCID: PMC4459732.
      Citations: 55     Fields:    Translation:HumansAnimalsCells
    47. Iribarne A, Burgener JD, Hong K, Raman J, Akhter S, Easterwood R, Jeevanandam V, Russo MJ. Quantifying the incremental cost of complications associated with mitral valve surgery in the United States. J Thorac Cardiovasc Surg. 2012 Apr; 143(4):864-72. PMID: 22424521.
      Citations: 8     Fields:    Translation:Humans
    48. Akhter SA. The heart and pericardium. Thorac Surg Clin. 2011 May; 21(2):205-17, viii. PMID: 21477771.
      Citations: 2     Fields:    Translation:Humans
    49. D'Souza KM, Malhotra R, Philip JL, Staron ML, Theccanat T, Jeevanandam V, Akhter SA. G protein-coupled receptor kinase-2 is a novel regulator of collagen synthesis in adult human cardiac fibroblasts. J Biol Chem. 2011 Apr 29; 286(17):15507-16. PMID: 21357420; PMCID: PMC3083230.
      Citations: 18     Fields:    Translation:HumansCells
    50. Malhotra R, Valuckaite V, Staron ML, Theccanat T, D'Souza KM, Alverdy JC, Akhter SA. High-molecular-weight polyethylene glycol protects cardiac myocytes from hypoxia- and reoxygenation-induced cell death and preserves ventricular function. Am J Physiol Heart Circ Physiol. 2011 May; 300(5):H1733-42. PMID: 21335476; PMCID: PMC3094071.
      Citations: 19     Fields:    Translation:AnimalsCells
    51. Koyner JL, Vaidya VS, Bennett MR, Ma Q, Worcester E, Akhter SA, Raman J, Jeevanandam V, O'Connor MF, Devarajan P, Bonventre JV, Murray PT. Urinary biomarkers in the clinical prognosis and early detection of acute kidney injury. Clin J Am Soc Nephrol. 2010 Dec; 5(12):2154-65. PMID: 20798258; PMCID: PMC2994075.
      Citations: 140     Fields:    Translation:Humans
    52. Lin E, Boire A, Hemmige V, Husain AN, Sorrentino M, Nathan S, Akhter SA, Dickstein J, Archer SL. Cardiac tamponade mimicking tuberculous pericarditis as the initial presentation of chronic lymphocytic leukemia in a 58-year-old woman: a case report. J Med Case Rep. 2010 Aug 04; 4:246. PMID: 20684780; PMCID: PMC2923171.
      Citations: 1     Fields:    
    53. Akhter SA, D'Souza KM, Malhotra R, Staron ML, Valeroso TB, Fedson SE, Anderson AS, Raman J, Jeevanandam V. Reversal of impaired myocardial beta-adrenergic receptor signaling by continuous-flow left ventricular assist device support. J Heart Lung Transplant. 2010 Jun; 29(6):603-9. PMID: 20202864; PMCID: PMC2876229.
      Citations: 12     Fields:    Translation:HumansCells
    54. Bulcao CF, D'Souza KM, Malhotra R, Staron M, Duffy JY, Pandalai PK, Jeevanandam V, Akhter SA. Activation of JAK-STAT and nitric oxide signaling as a mechanism for donor heart dysfunction. J Heart Lung Transplant. 2010 Mar; 29(3):346-51. PMID: 20022263; PMCID: PMC2833227.
      Citations: 11     Fields:    Translation:HumansCells
    55. Akhter SA, Raman J, Jeevanandam V. Technique for left ventricular apical cannulation for short-term mechanical circulatory support. Ann Thorac Surg. 2010 Mar; 89(3):994-5. PMID: 20172185.
      Citations: 3     Fields:    Translation:Humans
    56. Malhotra R, D'Souza KM, Staron ML, Birukov KG, Bodi I, Akhter SA. G alpha(q)-mediated activation of GRK2 by mechanical stretch in cardiac myocytes: the role of protein kinase C. J Biol Chem. 2010 Apr 30; 285(18):13748-60. PMID: 20194499; PMCID: PMC2859538.
      Citations: 17     Fields:    Translation:AnimalsCells
    57. Rajan S, Jagatheesan G, Karam CN, Alves ML, Bodi I, Schwartz A, Bulcao CF, D'Souza KM, Akhter SA, Boivin GP, Dube DK, Petrashevskaya N, Herr AB, Hullin R, Liggett SB, Wolska BM, Solaro RJ, Wieczorek DF. Molecular and functional characterization of a novel cardiac-specific human tropomyosin isoform. Circulation. 2010 Jan 26; 121(3):410-8. PMID: 20065163; PMCID: PMC2822663.
      Citations: 54     Fields:    Translation:HumansAnimalsCells
    58. Bulcao CF, Pandalai PK, D'Souza KM, Merrill WH, Akhter SA. Uncoupling of myocardial beta-adrenergic receptor signaling during coronary artery bypass grafting: the role of GRK2. Ann Thorac Surg. 2008 Oct; 86(4):1189-94. PMID: 18805158; PMCID: PMC2613564.
      Citations: 3     Fields:    Translation:HumansCells
    59. Pandalai PK, McLean KM, Bulcao CF, Duffy JY, D'Souza KM, Merrill WH, Pearl JM, Akhter SA. Acute beta-blockade prevents myocardial beta-adrenergic receptor desensitization and preserves early ventricular function after brain death. J Thorac Cardiovasc Surg. 2008 Apr; 135(4):792-8. PMID: 18374758.
      Citations: 3     Fields:    Translation:Animals
    60. D'Souza KM, Petrashevskaya NN, Merrill WH, Akhter SA. Inhibition of protein kinase C alpha improves myocardial beta-adrenergic receptor signaling and ventricular function in a model of myocardial preservation. J Thorac Cardiovasc Surg. 2008 Jan; 135(1):172-9, 179.e1. PMID: 18179937.
      Citations: 3     Fields:    Translation:AnimalsCells
    61. McLean KM, Pandalai PK, Pearl JM, Bulcao CF, Lyons JM, Wagner CJ, Akhter SA, Duffy JY. Beta-adrenergic receptor antagonism preserves myocardial function after brain death in a porcine model. J Heart Lung Transplant. 2007 May; 26(5):522-8. PMID: 17449424.
      Citations: 1     Fields:    Translation:Animals
    62. McLean KM, Duffy JY, Pandalai PK, Lyons JM, Bulcao CF, Wagner CJ, Akhter SA, Pearl JM. Glucocorticoids alter the balance between pro- and anti-inflammatory mediators in the myocardium in a porcine model of brain death. J Heart Lung Transplant. 2007 Jan; 26(1):78-84. PMID: 17234521.
      Citations: 7     Fields:    Translation:Animals
    63. Pandalai PK, Bulcao CF, Merrill WH, Akhter SA. Restoration of myocardial beta-adrenergic receptor signaling after left ventricular assist device support. J Thorac Cardiovasc Surg. 2006 May; 131(5):975-80. PMID: 16678578.
      Citations: 9     Fields:    Translation:HumansCells
    64. Akhter SA, D'Souza KM, Petrashevskaya NN, Mialet-Perez J, Liggett SB. Myocardial beta1-adrenergic receptor polymorphisms affect functional recovery after ischemic injury. Am J Physiol Heart Circ Physiol. 2006 Apr; 290(4):H1427-32. PMID: 16537791.
      Citations: 10     Fields:    Translation:AnimalsCells
    65. Bodi I, Mikala G, Koch SE, Akhter SA, Schwartz A. The L-type calcium channel in the heart: the beat goes on. J Clin Invest. 2005 Dec; 115(12):3306-17. PMID: 16322774; PMCID: PMC1297268.
      Citations: 113     Fields:    Translation:HumansAnimalsCells
    66. Lyons JM, Pearl JM, McLean KM, Akhter SA, Wagner CJ, Pandalai PK, Duffy JY. Glucocorticoid administration reduces cardiac dysfunction after brain death in pigs. J Heart Lung Transplant. 2005 Dec; 24(12):2249-54. PMID: 16364878.
      Citations: 5     Fields:    Translation:HumansAnimals
    67. Pandalai PK, Lyons JM, Duffy JY, McLean KM, Wagner CJ, Merrill WH, Pearl JM, Akhter SA. Role of the beta-adrenergic receptor kinase in myocardial dysfunction after brain death. J Thorac Cardiovasc Surg. 2005 Oct; 130(4):1183-9. PMID: 16214537.
      Citations: 2     Fields:    Translation:Animals
    68. Akhter SA, McGinty J, Konys JJ, Giesting RM, Merrill WH, Wagoner LE. Recurrent primary cardiac malignant fibrous histiocytoma following orthotopic heart transplantation. J Heart Lung Transplant. 2004 Dec; 23(12):1447-50. PMID: 15607678.
      Citations:    Fields:    Translation:Humans
    69. Petrashevskaya NN, Bodi I, Koch SE, Akhter SA, Schwartz A. Effects of alpha1-adrenergic stimulation on normal and hypertrophied mouse hearts. Relation to caveolin-3 expression. Cardiovasc Res. 2004 Aug 15; 63(3):561-72. PMID: 15276482.
      Citations: 7     Fields:    Translation:AnimalsCells
    70. Merrill WH, Akhter SA, Wolf RK, Schneeberger EW, Flege JB. Simplified treatment of postoperative mediastinitis. Ann Thorac Surg. 2004 Aug; 78(2):608-12; discussion 608-12. PMID: 15276531.
      Citations: 16     Fields:    Translation:Humans
    71. Schaeffer MW, Buell JF, Gupta M, Conway GD, Akhter SA, Wagoner LE. Strongyloides hyperinfection syndrome after heart transplantation: case report and review of the literature. J Heart Lung Transplant. 2004 Jul; 23(7):905-11. PMID: 15261189.
      Citations: 20     Fields:    Translation:Humans
    72. Akhter S, Kovbasnjuk O, Li X, Cavet M, Noel J, Arpin M, Hubbard AL, Donowitz M. Na(+)/H(+) exchanger 3 is in large complexes in the center of the apical surface of proximal tubule-derived OK cells. Am J Physiol Cell Physiol. 2002 Sep; 283(3):C927-40. PMID: 12176749.
      Citations: 28     Fields:    Translation:AnimalsCells
    73. Kalkeri G, Khalap N, Akhter S, Garry RF, Fermin CD, Dash S. Hepatitis C viral proteins affect cell viability and membrane permeability. Exp Mol Pathol. 2001 Dec; 71(3):194-208. PMID: 11733945.
      Citations: 5     Fields:    Translation:HumansCells
    74. Chen EP, Bittner HB, Akhter SA, Koch WJ, Davis RD. Myocardial function in hearts with transgenic overexpression of the G protein-coupled receptor kinase 5. Ann Thorac Surg. 2001 Apr; 71(4):1320-4. PMID: 11308180.
      Citations: 18     Fields:    Translation:Animals
    75. Janecki AJ, Janecki M, Akhter S, Donowitz M. Quantitation of plasma membrane expression of a fusion protein of Na/H exchanger NHE3 and green fluorescence protein (GFP) in living PS120 fibroblasts. J Histochem Cytochem. 2000 Nov; 48(11):1479-92. PMID: 11036091.
      Citations: 9     Fields:    Translation:AnimalsCells
    76. Islam A, Vladutiu AO, Donahue T, Akhter S, Sands AM, Ambrus JL. CD8 expression on B cells in chronic lymphocytic leukemia: a case report and review of the literature. Arch Pathol Lab Med. 2000 Sep; 124(9):1361-3. PMID: 10975939.
      Citations: 5     Fields:    Translation:HumansCells
    77. Donowitz M, Janecki A, Akhter S, Cavet ME, Sanchez F, Lamprecht G, Zizak M, Kwon WL, Khurana S, Yun CH, Tse CM. Short-term regulation of NHE3 by EGF and protein kinase C but not protein kinase A involves vesicle trafficking in epithelial cells and fibroblasts. Ann N Y Acad Sci. 2000; 915:30-42. PMID: 11193592.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    78. Cavet ME, Akhter S, de Medina FS, Donowitz M, Tse CM. Na(+)/H(+) exchangers (NHE1-3) have similar turnover numbers but different percentages on the cell surface. Am J Physiol. 1999 12; 277(6):C1111-21. PMID: 10600762.
      Citations: 13     Fields:    Translation:AnimalsCells
    79. Akhter SA, Eckhart AD, Rockman HA, Shotwell K, Lefkowitz RJ, Koch WJ. In vivo inhibition of elevated myocardial beta-adrenergic receptor kinase activity in hybrid transgenic mice restores normal beta-adrenergic signaling and function. Circulation. 1999 Aug 10; 100(6):648-53. PMID: 10441103.
      Citations: 27     Fields:    Translation:AnimalsCells
    80. Kypson A, Hendrickson S, Akhter S, Wilson K, McDonald P, Lilly R, Dolber P, Glower D, Lefkowitz R, Koch W. Adenovirus-mediated gene transfer of the beta2-adrenergic receptor to donor hearts enhances cardiac function. Gene Ther. 1999 Jul; 6(7):1298-304. PMID: 10455439.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    81. Chen EP, Akhter SA, Bittner HB, Koch WJ, Davis RD, Van Trigt P. Molecular and functional mechanisms of right ventricular adaptation in chronic pulmonary hypertension. Ann Thorac Surg. 1999 Apr; 67(4):1053-8. PMID: 10320250.
      Citations: 5     Fields:    Translation:Animals
    82. Xiao RP, Avdonin P, Zhou YY, Cheng H, Akhter SA, Eschenhagen T, Lefkowitz RJ, Koch WJ, Lakatta EG. Coupling of beta2-adrenoceptor to Gi proteins and its physiological relevance in murine cardiac myocytes. Circ Res. 1999 Jan 8-22; 84(1):43-52. PMID: 9915773.
      Citations: 116     Fields:    Translation:HumansAnimalsCells
    83. Chen EP, Bittner HB, Akhter SA, Koch WJ, Davis RD. Myocardial recovery after ischemia and reperfusion injury is significantly impaired in hearts with transgenic overexpression of beta-adrenergic receptor kinase. Circulation. 1998 Nov 10; 98(19 Suppl):II249-53; discussion II253-4. PMID: 9852910.
      Citations: 2     Fields:    Translation:Animals
    84. Rockman HA, Choi DJ, Akhter SA, Jaber M, Giros B, Lefkowitz RJ, Caron MG, Koch WJ. Control of myocardial contractile function by the level of beta-adrenergic receptor kinase 1 in gene-targeted mice. J Biol Chem. 1998 Jul 17; 273(29):18180-4. PMID: 9660778.
      Citations: 47     Fields:    Translation:AnimalsCells
    85. Akhter SA, Luttrell LM, Rockman HA, Iaccarino G, Lefkowitz RJ, Koch WJ. Targeting the receptor-Gq interface to inhibit in vivo pressure overload myocardial hypertrophy. Science. 1998 Apr 24; 280(5363):574-7. PMID: 9554846.
      Citations: 112     Fields:    Translation:AnimalsCells
    86. Kypson AP, Peppel K, Akhter SA, Lilly RE, Glower DD, Lefkowitz RJ, Koch WJ. Ex vivo adenovirus-mediated gene transfer to the adult rat heart. J Thorac Cardiovasc Surg. 1998 Mar; 115(3):623-30. PMID: 9535450.
      Citations: 8     Fields:    Translation:AnimalsCells
    87. Koch WJ, Lefkowitz RJ, Milano CA, Akhter SA, Rockman HA. Myocardial overexpression of adrenergic receptors and receptor kinases. Adv Pharmacol. 1998; 42:502-6. PMID: 9327950.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    88. Akhter SA, Skaer CA, Kypson AP, McDonald PH, Peppel KC, Glower DD, Lefkowitz RJ, Koch WJ. Restoration of beta-adrenergic signaling in failing cardiac ventricular myocytes via adenoviral-mediated gene transfer. Proc Natl Acad Sci U S A. 1997 Oct 28; 94(22):12100-5. PMID: 9342369; PMCID: PMC23716.
      Citations: 37     Fields:    Translation:AnimalsCells
    89. Akhter SA, Milano CA, Shotwell KF, Cho MC, Rockman HA, Lefkowitz RJ, Koch WJ. Transgenic mice with cardiac overexpression of alpha1B-adrenergic receptors. In vivo alpha1-adrenergic receptor-mediated regulation of beta-adrenergic signaling. J Biol Chem. 1997 Aug 22; 272(34):21253-9. PMID: 9261135.
      Citations: 28     Fields:    Translation:AnimalsCells
    90. Rockman HA, Choi DJ, Rahman NU, Akhter SA, Lefkowitz RJ, Koch WJ. Receptor-specific in vivo desensitization by the G protein-coupled receptor kinase-5 in transgenic mice. Proc Natl Acad Sci U S A. 1996 Sep 03; 93(18):9954-9. PMID: 8790438; PMCID: PMC38536.
      Citations: 70     Fields:    Translation:Animals
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