 DNA-Directed RNA Polymerases
"DNA-Directed RNA Polymerases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enzymes that catalyze DNA template-directed extension of the 3'-end of an RNA strand one nucleotide at a time. They can initiate a chain de novo. In eukaryotes, three forms of the enzyme have been distinguished on the basis of sensitivity to alpha-amanitin, and the type of RNA synthesized. (From Enzyme Nomenclature, 1992).
| Descriptor ID |
D012321
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| MeSH Number(s) |
D08.811.913.696.445.735.270
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| Concept/Terms |
DNA-Directed RNA Polymerases- DNA-Directed RNA Polymerases
- DNA Directed RNA Polymerases
- Polymerases, DNA-Directed RNA
- RNA Polymerases, DNA-Directed
- RNA Polymerase
- Polymerase, RNA
- Transcriptases
- DNA-Directed RNA Polymerase
- DNA Directed RNA Polymerase
- Polymerase, DNA-Directed RNA
- RNA Polymerase, DNA-Directed
- DNA-Dependent RNA Polymerases
- DNA Dependent RNA Polymerases
- Polymerases, DNA-Dependent RNA
- RNA Polymerases, DNA-Dependent
- RNA Polymerases
- Polymerases, RNA
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Below are MeSH descriptors whose meaning is more general than "DNA-Directed RNA Polymerases".
Below are MeSH descriptors whose meaning is more specific than "DNA-Directed RNA Polymerases".
This graph shows the total number of publications written about "DNA-Directed RNA Polymerases" by people in this website by year, and whether "DNA-Directed RNA Polymerases" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 1980 | 1 | 0 | 1 | | 1981 | 0 | 1 | 1 | | 1983 | 2 | 0 | 2 | | 1985 | 1 | 1 | 2 | | 1986 | 0 | 2 | 2 | | 1987 | 2 | 0 | 2 | | 1988 | 3 | 1 | 4 | | 1990 | 1 | 1 | 2 | | 1991 | 5 | 0 | 5 | | 1992 | 4 | 0 | 4 | | 1995 | 1 | 0 | 1 | | 1996 | 2 | 0 | 2 | | 1997 | 2 | 0 | 2 | | 1998 | 2 | 0 | 2 | | 2000 | 1 | 0 | 1 | | 2001 | 0 | 1 | 1 | | 2002 | 1 | 2 | 3 | | 2003 | 2 | 0 | 2 | | 2005 | 0 | 1 | 1 | | 2006 | 1 | 0 | 1 | | 2007 | 1 | 1 | 2 | | 2008 | 4 | 0 | 4 | | 2009 | 0 | 3 | 3 | | 2010 | 0 | 1 | 1 | | 2011 | 3 | 3 | 6 | | 2012 | 0 | 1 | 1 | | 2013 | 2 | 1 | 3 | | 2014 | 1 | 0 | 1 | | 2015 | 2 | 2 | 4 | | 2016 | 1 | 1 | 2 | | 2017 | 3 | 0 | 3 | | 2018 | 1 | 1 | 2 | | 2019 | 1 | 0 | 1 | | 2020 | 1 | 0 | 1 | | 2021 | 1 | 1 | 2 | | 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "DNA-Directed RNA Polymerases" by people in Profiles.
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Urusova DV, Merriman JA, Gupta A, Chen L, Mathema B, Caparon MG, Khader SA. Rifampin resistance mutations in the rpoB gene of Enterococcus faecalis impact host macrophage cytokine production. Cytokine. 2022 03; 151:155788.
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Dewey JA, Azizi SA, Lu V, Dickinson BC. A System for the Evolution of Protein-Protein Interaction Inducers. ACS Synth Biol. 2021 08 20; 10(8):2096-2110.
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DasGupta S, Nykiel K, Piccirilli JA. The hammerhead self-cleaving motif as a precursor to complex endonucleolytic ribozymes. RNA. 2021 09; 27(9):1017-1024.
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Dewey JA, Dickinson BC. Split T7 RNA polymerase biosensors to study multiprotein interaction dynamics. Methods Enzymol. 2020; 641:413-432.
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Pu J, Disare M, Dickinson BC. Evolution of C-Terminal Modification Tolerance in Full-Length and Split T7 RNA Polymerase Biosensors. Chembiochem. 2019 06 14; 20(12):1547-1553.
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Howard NC, Marin ND, Ahmed M, Rosa BA, Martin J, Bambouskova M, Sergushichev A, Loginicheva E, Kurepina N, Rangel-Moreno J, Chen L, Kreiswirth BN, Klein RS, Balada-Llasat JM, Torrelles JB, Amarasinghe GK, Mitreva M, Artyomov MN, Hsu FF, Mathema B, Khader SA. Mycobacterium tuberculosis carrying a rifampicin drug resistance mutation reprograms macrophage metabolism through cell wall lipid changes. Nat Microbiol. 2018 10; 3(10):1099-1108.
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Kociolek LK, Ozer EA, Gerding DN, Hecht DW, Patel SJ, Hauser AR. Whole-genome analysis reveals the evolution and transmission of an MDR DH/NAP11/106 Clostridium difficile clone in a paediatric hospital. J Antimicrob Chemother. 2018 05 01; 73(5):1222-1229.
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Pu J, Kentala K, Dickinson BC. Multidimensional Control of Cas9 by Evolved RNA Polymerase-Based Biosensors. ACS Chem Biol. 2018 02 16; 13(2):431-437.
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Pu J, Dewey JA, Hadji A, LaBelle JL, Dickinson BC. RNA Polymerase Tags To Monitor Multidimensional Protein-Protein Interactions Reveal Pharmacological Engagement of Bcl-2 Proteins. J Am Chem Soc. 2017 08 30; 139(34):11964-11972.
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Pu J, Zinkus-Boltz J, Dickinson BC. Evolution of a split RNA polymerase as a versatile biosensor platform. Nat Chem Biol. 2017 04; 13(4):432-438.
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