DNA-Directed RNA Polymerases
"DNA-Directed RNA Polymerases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enzymes that catalyze DNA template-directed extension of the 3'-end of an RNA strand one nucleotide at a time. They can initiate a chain de novo. In eukaryotes, three forms of the enzyme have been distinguished on the basis of sensitivity to alpha-amanitin, and the type of RNA synthesized. (From Enzyme Nomenclature, 1992).
| Descriptor ID |
D012321
|
| MeSH Number(s) |
D08.811.913.696.445.735.270
|
| Concept/Terms |
DNA-Directed RNA Polymerases- DNA-Directed RNA Polymerases
- DNA Directed RNA Polymerases
- Polymerases, DNA-Directed RNA
- RNA Polymerases, DNA-Directed
- RNA Polymerase
- Polymerase, RNA
- Transcriptases
- DNA-Directed RNA Polymerase
- DNA Directed RNA Polymerase
- Polymerase, DNA-Directed RNA
- RNA Polymerase, DNA-Directed
- DNA-Dependent RNA Polymerases
- DNA Dependent RNA Polymerases
- Polymerases, DNA-Dependent RNA
- RNA Polymerases, DNA-Dependent
- RNA Polymerases
- Polymerases, RNA
|
Below are MeSH descriptors whose meaning is more general than "DNA-Directed RNA Polymerases".
Below are MeSH descriptors whose meaning is more specific than "DNA-Directed RNA Polymerases".
This graph shows the total number of publications written about "DNA-Directed RNA Polymerases" by people in this website by year, and whether "DNA-Directed RNA Polymerases" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
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| 1995 | 1 | 0 | 1 |
| 1996 | 2 | 0 | 2 |
| 1997 | 2 | 0 | 2 |
| 1998 | 2 | 0 | 2 |
| 2000 | 1 | 0 | 1 |
| 2001 | 0 | 1 | 1 |
| 2002 | 1 | 2 | 3 |
| 2003 | 2 | 0 | 2 |
| 2005 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 4 | 0 | 4 |
| 2009 | 0 | 3 | 3 |
| 2010 | 0 | 1 | 1 |
| 2011 | 3 | 3 | 6 |
| 2012 | 0 | 1 | 1 |
| 2013 | 2 | 1 | 3 |
| 2014 | 1 | 0 | 1 |
| 2015 | 2 | 2 | 4 |
| 2016 | 1 | 1 | 2 |
| 2017 | 3 | 0 | 3 |
| 2018 | 1 | 1 | 2 |
| 2019 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
| 2021 | 1 | 1 | 2 |
| 2022 | 0 | 1 | 1 |
| 2023 | 1 | 1 | 2 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "DNA-Directed RNA Polymerases" by people in Profiles.
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A protective role for type I interferon signaling following infection with Mycobacterium tuberculosis carrying the rifampicin drug resistance-conferring RpoB mutation H445Y. PLoS Pathog. 2024 Apr; 20(4):e1012137.
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Mycobacterium tuberculosis carrying the rifampicin drug-resistance-conferring rpoB mutation H445Y is associated with suppressed immunity through type I interferons. mBio. 2023 Oct 31; 14(5):e0094623.
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Promoter-independent synthesis of chemically modified RNA by human DNA polymerase ? variants. RNA. 2023 08; 29(8):1288-1300.
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Rifampin resistance mutations in the rpoB gene of Enterococcus faecalis impact host macrophage cytokine production. Cytokine. 2022 03; 151:155788.
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A System for the Evolution of Protein-Protein Interaction Inducers. ACS Synth Biol. 2021 08 20; 10(8):2096-2110.
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The hammerhead self-cleaving motif as a precursor to complex endonucleolytic ribozymes. RNA. 2021 09; 27(9):1017-1024.
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Split T7 RNA polymerase biosensors to study multiprotein interaction dynamics. Methods Enzymol. 2020; 641:413-432.
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Evolution of C-Terminal Modification Tolerance in Full-Length and Split T7 RNA Polymerase Biosensors. Chembiochem. 2019 06 14; 20(12):1547-1553.
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Mycobacterium tuberculosis carrying a rifampicin drug resistance mutation reprograms macrophage metabolism through cell wall lipid changes. Nat Microbiol. 2018 10; 3(10):1099-1108.
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Whole-genome analysis reveals the evolution and transmission of an MDR DH/NAP11/106 Clostridium difficile clone in a paediatric hospital. J Antimicrob Chemother. 2018 05 01; 73(5):1222-1229.