 Hydroxymethylglutaryl-CoA Synthase
"Hydroxymethylglutaryl-CoA Synthase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the synthesis of hydroxymethylglutaryl-CoA from acetyl-CoA and acetoacetyl-CoA. This is a key enzyme in steroid biosynthesis. This enzyme was formerly listed as EC 4.1.3.5.
| Descriptor ID |
D006904
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| MeSH Number(s) |
D08.811.913.050.612
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| Concept/Terms |
Hydroxymethylglutaryl-CoA Synthase- Hydroxymethylglutaryl-CoA Synthase
- Hydroxymethylglutaryl CoA Synthase
- Synthase, Hydroxymethylglutaryl-CoA
- 3-hydroxy-3-methylglutaryl-coenzyme A synthase
- HMG-CoA synthase
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Below are MeSH descriptors whose meaning is more general than "Hydroxymethylglutaryl-CoA Synthase".
Below are MeSH descriptors whose meaning is more specific than "Hydroxymethylglutaryl-CoA Synthase".
This graph shows the total number of publications written about "Hydroxymethylglutaryl-CoA Synthase" by people in this website by year, and whether "Hydroxymethylglutaryl-CoA Synthase" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1991 | 0 | 1 | 1 | | 1995 | 0 | 1 | 1 | | 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Hydroxymethylglutaryl-CoA Synthase" by people in Profiles.
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Singh S, McDonough CW, Gong Y, Alghamdi WA, Arwood MJ, Bargal SA, Dumeny L, Li WY, Mehanna M, Stockard B, Yang G, de Oliveira FA, Fredette NC, Shahin MH, Bailey KR, Beitelshees AL, Boerwinkle E, Chapman AB, Gums JG, Turner ST, Cooper-DeHoff RM, Johnson JA. Genome Wide Association Study Identifies the HMGCS2 Locus to be Associated With Chlorthalidone Induced Glucose Increase in Hypertensive Patients. J Am Heart Assoc. 2018 03 09; 7(6).
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Kushwaha RS, Barrett PH, Reardon CA, Lewis DS, Carey KD, Getz GS, McGill HC. Relationships of plasma and hepatic variables with rates of plasma low-density lipoprotein apolipoprotein B metabolism in baboons fed low- and high-fat diets. Metabolism. 1995 Aug; 44(8):1058-66.
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Kushwaha RS, McMahan CA, Mott GE, Carey KD, Reardon CA, Getz GS, McGill HC. Influence of dietary lipids on hepatic mRNA levels of proteins regulating plasma lipoproteins in baboons with high and low levels of large high density lipoproteins. J Lipid Res. 1991 Dec; 32(12):1929-40.
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